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References from Mitochondria-ER-lipid droplet crosstalk regulates metabolic adaptation to shear stress via VMP1. Local targets link to admitted publications; unresolved targets remain external evidence.
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells
10.1073/pnas.1015751107 · 2010 · External reference
Sensing of tubular flow and renal electrolyte transport
10.1038/s41581-020-0259-8 · 2020 · External reference
The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells
10.1038/s41556-020-0566-0 · 2020 · External reference
Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow
10.1038/ncb3360 · 2016 · External reference
Beyond fission and fusion-Diving into the mysteries of mitochondrial shape
10.1371/journal.pbio.3002671 · 2024 · External reference
Endoplasmic reticulum membrane and contact site dynamics in autophagy regulation and stress response
10.3389/fcell.2020.00343 · 2020 · External reference
The functional universe of membrane contact sites
10.1038/s41580-019-0180-9 · 2020 · External reference
The ER-mitochondria interface, where Ca2+ and cell death meet
10.1016/j.ceca.2023.102743 · 2023 · External reference
Endoplasmic reticulum-mitochondria contacts: Function of the junction
10.1038/nrm3440 · 2012 · External reference
Mitochondrial organization in the developing proximal tubule is controlled by LRRK2
10.1038/s41467-025-64598-2 · 2025 · External reference
Mitochondrial dynamics regulates Drosophila intestinal stem cell differentiation
10.1038/s41420-018-0083-0 · 2018 · External reference
Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases
10.1186/s12967-024-05041-w · 2024 · External reference
Mitochondrial dynamics in postmitotic cells regulate neurogenesis
10.1126/science.aba9760 · 2020 · External reference
Primary cilia regulate mTORC1 activity and cell size through Lkb1
10.1038/ncb2117 · 2010 · External reference
Visualization and quantification of mitochondrial structure in the endothelium of intact arteries
10.1093/cvr/cvy294 · 2019 · External reference
Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
10.1172/jci37829 · 2009 · External reference
Quantitative Super-Resolution Microscopy Reveals Promoting Mitochondrial Interconnectivity Protects against AKI
10.34067/kid.0001602021 · 2021 · External reference
Primary cilium-dependent autophagy in the response to shear stress
10.1042/bst20210810 · 2021 · External reference
Determinants and outcomes of mitochondrial dynamics
10.1016/j.molcel.2023.02.012 · 2023 · External reference
Computational classification of mitochondrial shapes reflects stress and redox state
10.1038/cddis.2012.213 · 2013 · External reference
Fluid flow-induced shear stress controls the metabolism of proximal tubule kidney epithelial cells through primary cilium-dependent lipophagy and mitochondria biogenesis
10.1080/15548627.2020.1823125 · 2020 · External reference
The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros
10.1016/j.ydbio.2007.06.022 · 2007 · External reference
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
10.1242/dev.125.23.4655 · 1998 · External reference
A guide to characterizing the dynamic mitochondria-endoplasmic reticulum contact sites
10.1111/febs.70184 · 2025 · External reference
The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy
10.1016/j.cub.2016.12.038 · 2017 · External reference
Modulation of ER-mitochondria tethering complex VAPB-PTPIP51: Novel therapeutic targets for aging-associated diseases
10.1016/j.arr.2024.102320 · 2024 · External reference
Split-TurboID enables contact-dependent proximity labeling in cells
10.1073/pnas.1919528117 · 2020 · External reference
Here, there, and everywhere: The importance of ER membrane contact sites
10.1126/science.aan5835 · 2018 · External reference
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
10.1038/nature07534 · 2008 · External reference
Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed
10.1073/pnas.1504487112 · 2015 · External reference
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites
10.1083/jcb.201807019 · 2018 · External reference
In situ architecture of the lipid transport protein VPS13C at ER-lysosome membrane contacts
10.1073/pnas.2203769119 · 2022 · External reference
The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage
10.1038/s41556-025-01653-6 · 2025 · External reference
A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane
10.1073/pnas.2205425119 · 2022 · External reference
A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets
10.1038/s44319-024-00266-8 · 2024 · External reference
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
10.1038/s41467-025-57405-5 · 2025 · External reference
Mfn2/Hsc70 Complex Mediates the Formation of Mitochondria-Lipid Droplets Membrane Contact and Regulates Myocardial Lipid Metabolism
10.4028/b-7tthnx · 2024 · External reference
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites
10.1083/jcb.202112107 · 2022 · External reference
Molecular Interactions at Lipid Droplet–Mitochondria Membrane Contact Sites in Mammalian Cells
10.3390/lipidology2030016 · 2025 · External reference
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport
10.1016/j.devcel.2023.05.006 · 2023 · External reference
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine
10.1083/jcb.202103105 · 2021 · External reference
VMP1 establishes ER-microdomains that regulate membrane contact sites and autophagy
10.1371/journal.pone.0166499 · 2016 · External reference
ER-plasma membrane contact sites contribute to autophagosome biogenesis by regulation of local PI3P synthesis
10.15252/embj.201797006 · 2017 · External reference
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection
10.1083/jcb.202112081 · 2022 · External reference
TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection
10.1371/journal.ppat.1010763 · 2022 · External reference
Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis
10.1016/j.jhep.2022.04.010 · 2022 · External reference
The scramblases VMP1 and TMEM41B are required for primitive endoderm specification by targeting WNT signaling
10.1038/s41418-024-01435-x · 2024 · External reference
Loss of hepatic VMP1 trapped VLDL in the bilayer of endoplasmic reticulum membrane☆
10.1016/j.livres.2023.04.001 · 2023 · External reference
Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts
10.1016/0885-4505(92)90056-5 · 1992 · External reference
Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis
10.1016/j.cmet.2023.01.003 · 2023 · External reference
Mitochondrial plasticity in cell fate regulation
10.1074/jbc.rev118.000828 · 2019 · External reference
Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and disease
10.1016/j.cub.2021.04.062 · 2021 · External reference
Renal tubular VMP1 protects against acute kidney injury via modulating autophagy and autophagy-independent pathway
10.1080/15548627.2025.2533306 · 2025 · External reference
The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells
10.1038/s41467-023-43775-1 · 2023 · External reference
Autophagosomes form at ER-mitochondria contact sites
10.1038/nature11910 · 2013 · External reference
ER-endosome contacts generate a local environment promoting phagophore formation
10.1016/j.celrep.2025.115993 · 2025 · External reference
Autophagosomes contribute to intracellular lipid distribution in enterocytes
10.1091/mbc.e13-06-0324 · 2014 · External reference
VMP1 attenuates ferroptosis and mitochondrial dysfunction in nucleus pulposus cells through the PINK1/Parkin-mediated mitophagy pathway
2025 · External reference
Mitochondrial Dynamics and VMP1-Related Selective Mitophagy in Experimental Acute Pancreatitis
10.3389/fcell.2021.640094 · 2021 · External reference
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation
10.1016/j.molcel.2017.08.005 · 2017 · External reference
A third-generation lentivirus vector with a conditional packaging system
10.1128/jvi.72.11.8463-8471.1998 · 1998 · External reference
Ubiquitination Is a Novel Post-Translational Modification of VMP1 in Autophagy of Human Tumor Cells
10.3390/ijms241612981 · 2023 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Icy: an open bioimage informatics platform for extended reproducible research
10.1038/nmeth.2075 · 2012 · External reference
