Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Tissue- and time-dependent deployment of Toll- and Imd-associated immune responses in Manduca sexta larvae. Local targets link to admitted publications; unresolved targets remain external evidence.
Insect fat body: energy, metabolism, and regulation
10.1146/annurev-ento-112408-085356 · 2010 · External reference
Fast unfolding of communities in large networks
2008 · External reference
Immunity in Drosophila melanogaster - from microbial recognition to whole-organism physiology
10.1038/nri3763 · 2014 · External reference
The immune signaling pathways of
10.1016/j.ibmb.2015.03.006 · 2015 · External reference
Sequence conservation, phylogenetic relationships, and expression profiles of nondigestive serine proteases and serine protease homologs in Manduca sexta
10.1016/j.ibmb.2014.10.006 · 2015 · External reference
An analysis of 67 RNA-seq datasets from various tissues at different stages of a model insect
10.1186/s12864-017-4147-y · 2017 · External reference
Immunity-related genes and gene families in Anopheles gambiae
10.1126/science.1077136 · 2002 · External reference
Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
10.1073/pnas.221458698 · 2001 · External reference
The Toll and Imd pathways are the major regulators of the immune response in Drosophila
10.1093/emboj/21.11.2568 · 2002 · External reference
Molecular regulations of metabolism during immune response in insects
10.1016/j.ibmb.2019.04.005 · 2019 · External reference
Fate of bacteria injected into naive and immunized larvae of the tobacco hornworm
10.1016/0022-2011(83)90238-0 · 1983 · External reference
A comprehensive analysis of Manduca sexta immunotranscriptome
10.1016/j.dci.2012.10.004 · 2013 · External reference
A genome-wide analysis of antimicrobial effector genes and their transcription patterns in Manduca sexta
10.1016/j.ibmb.2015.01.015 · 2015 · External reference
Insect immunology and hematopoiesis
10.1016/j.dci.2015.12.006 · 2016 · External reference
Extracellular nutrient digestion and absorption in the insect gut
10.1007/s00441-019-03031-9 · 2019 · External reference
Pattern recognition, hemolymph protease-14 activation, and enhancement of lysozyme-mediated bacteria killing by soluble peptidoglycan recognition proteins in Manduca sexta
10.1016/j.ibmb.2025.104297 · 2025 · External reference
The circulating protease Persephone is an immune sensor for microbial proteolytic activities upstream of the Drosophila Toll pathway
10.1016/j.molcel.2018.01.029 · 2018 · External reference
Immunity in lepidopteran insects
10.1007/978-1-4419-8059-5_10 · 2010 · External reference
Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta
10.1016/j.ibmb.2016.07.005 · 2016 · External reference
Preferential binding of DAP-PGs by major peptidoglycan recognition proteins found in cell-free hemolymph of Manduca sexta
10.1016/j.ibmb.2022.103827 · 2022 · External reference
Insect antiviral innate immunity: pathways, effectors, and connections
10.1016/j.jmb.2013.10.006 · 2013 · External reference
GOATOOLS: a Python library for Gene Ontology analyses
10.1038/s41598-018-28948-z · 2018 · External reference
The Drosophila melanogaster Toll pathway participates in resistance to infection by the Gram-negative human pathogen Pseudomonas aeruginosa
10.1128/iai.71.7.4059-4066.2003 · 2003 · External reference
Insect hemocytes and their role in immunity
10.1016/s0965-1748(02)00092-9 · 2002 · External reference
The host defense of Drosophila melanogaster
10.1146/annurev.immunol.25.022106.141615 · 2007 · External reference
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
10.1038/ni922 · 2003 · External reference
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
10.1186/1471-2105-12-323 · 2011 · External reference
The Manduca sexta serpinome: analysis of serpin genes and proteins in the tobacco hornworm
10.1016/j.ibmb.2018.09.008 · 2018 · External reference
Sensing microbial infections in the Drosophila melanogaster genetic model organism
10.1007/s00251-021-01239-0 · 2022 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Identification of immunity-related genes distinctly regulated by Manduca sexta Spӓtzle-1/2 and Escherichia coli peptidoglycan
10.1016/j.ibmb.2024.104108 · 2024 · External reference
The Drosophila imd signaling pathway
10.4049/jimmunol.1303309 · 2014 · External reference
An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila
10.1126/sciadv.adk2756 · 2023 · External reference
Fat body, multifunctional insect tissue
10.3390/insects12060547 · 2021 · External reference
Beyond cellular immunity: on the biological significance of insect hemocytes
10.3390/cells12040599 · 2023 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
The Drosophila Toll signaling pathway
10.4049/jimmunol.1002302 · 2011 · External reference
Accessibility to peptidoglycan is important for the recognition of Gram-positive bacteria in Drosophila
10.1016/j.celrep.2019.04.103 · 2019 · External reference
Prophenoloxidase activation and antimicrobial peptide expression induced by the recombinant microbe binding protein of Manduca sexta
10.1016/j.ibmb.2016.10.006 · 2017 · External reference
A mechanistic analysis of bacterial recognition and serine protease cascade initiation in larval hemolymph of Manduca sexta
10.1016/j.ibmb.2022.103818 · 2022 · External reference
Toll9 from Bombyx mori functions as a pattern recognition receptor that shares features with Toll-like receptor 4 from mammals
2021 · External reference
Pyrosequencing-based expression profiling and identification of differentially regulated genes from Manduca sexta, a lepidopteran model insect
10.1016/j.ibmb.2011.05.005 · 2011 · External reference
Phylogenetic analysis and expression profiling of the pattern recognition receptors: insights into molecular recognition of invading pathogens in Manduca sexta
10.1016/j.ibmb.2015.02.001 · 2015 · External reference
Comparative genome analysis of the Tribolium immune system
10.1186/gb-2007-8-8-r177 · 2007 · External reference
