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References from Involvement of LTB4 and a CXCR4-like protein in extracellular trap formation in Ruditapes philippinarum. Local targets link to admitted publications; unresolved targets remain external evidence.
ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production
2022 · External reference
Transcriptomic responses in rainbow trout gills upon infection with viral hemorrhagic septicemia virus (VHSV)
10.1016/j.dci.2013.11.006 · 2014 · External reference
Cloning, characterization and expression analysis of a CXCR1-like gene from mandarin fish Siniperca chuatsi
10.1007/s10695-008-9283-5 · 2009 · External reference
Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species
10.1007/s10059-011-1021-7 · 2011 · External reference
Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish
10.1189/jlb.1012534 · 2013 · External reference
Reactive oxygen species: a novel antimicrobial
10.1016/j.ijantimicag.2017.08.029 · 2018 · External reference
Oxidative stress response of the black tiger shrimp Penaeus monodon to Vibrio parahaemolyticus challenge
10.1016/j.fsi.2015.06.032 · 2015 · External reference
Role of a ficolin in the innate immune mechanisms of Penaeus vannamei against Vibrio parahaemolyticus
10.1016/j.fsi.2025.110950 · 2026 · External reference
Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum
10.1016/j.dci.2021.104094 · 2021 · External reference
In vitro study of deltamethrin-induced extracellular traps in hemocytes of Ruditapes philippinarum
10.1016/j.ecoenv.2023.114909 · 2023 · External reference
The role of the LTB4-BLT1 axis in health and disease
10.1016/j.phrs.2020.104857 · 2020 · External reference
Pathogen recognition and mechanisms in Atlantic cod (Gadus morhua) head kidney cells: Bacteria (LPS) and virus (poly I:C) signals through different pathways and affect distinct genes
10.1016/j.fsi.2012.05.013 · 2012 · External reference
β-naphthoflavone interferes with cyp1c1, cox2 and IL-8 gene transcription and leukotriene B4 secretion in Atlantic cod (Gadus morhua) head kidney cells during inflammation
10.1016/j.fsi.2016.03.043 · 2016 · External reference
Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis
10.1186/s12929-023-00957-9 · 2023 · External reference
Extracellular trap formation in kuruma shrimp (Marsupenaeus japonicus) hemocytes is coupled with c-type lysozyme
10.1016/j.fsi.2016.03.039 · 2016 · External reference
10.1126/sciadv.aeb8034
10.1126/sciadv.aeb8034 · External reference
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation
10.7150/thno.63751 · 2022 · External reference
Profiles of extracellular vesicle shutter proteins from Chlamys farreri stimulated by lipopolysaccharide
10.1016/j.dci.2025.105435 · 2025 · External reference
Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway
10.1002/ctm2.1483 · 2023 · External reference
Grouper (Epinephelus coioides) CXCR4 is expressed in response to pathogens infection and early stage of development
10.1016/j.dci.2011.06.009 · 2012 · External reference
Neutrophil-activating therapy for the treatment of cancer
10.1016/j.ccell.2023.01.002 · 2023 · External reference
Environmental influence on summer survival of Manila Clam Ruditapes philippinarum: a case study in an aquaculture bay
10.1016/j.marenvres.2023.106242 · 2023 · External reference
CXCR family and hematologic malignancies in the bone marrow microenvironment
10.3390/biom15050716 · 2025 · External reference
CXCR4s in teleosts: two paralogous chemokine receptors and their roles in hematopoietic Stem/Progenitor cell homeostasis
10.4049/jimmunol.1901100 · 2020 · External reference
LTB4 promotes acute lung injury via upregulating the PLCε-1/TLR4/NF-κB pathway in one-lung ventilation
10.1155/2022/1839341 · 2022 · External reference
Nonylphenol displays immunotoxicity by triggering hemocyte extracellular traps in Manila clam via ROS burst, ERK pathway and glycolysis
10.1016/j.ecoenv.2024.117145 · 2024 · External reference
RNA-Seq in Mytilus galloprovincialis: comparative transcriptomics and expression profiles among different tissues
10.1186/s12864-015-1817-5 · 2015 · External reference
Extracellular traps: an Ancient weapon of multiple kingdoms
10.3390/biology9020034 · 2020 · External reference
Shrimp hemocytes release extracellular traps that kill bacteria
10.1016/j.dci.2013.06.014 · 2013 · External reference
Abstract 197: LPS-induced superoxide anion-dependent macrophage extracellular traps by store-operated calcium entry
2026 · External reference
Transcriptome analysis reveals differential immune related genes expression in Ruditapes philippinarum under hypoxia stress: potential HIF and NF-κB crosstalk in immune responses in clam
10.1186/s12864-020-6734-6 · 2020 · External reference
Chemokine CXCb1 stimulates formation of NETs in trunk kidney neutrophils of common carp
10.1016/j.dci.2019.103521 · 2020 · External reference
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
10.1016/j.cellsig.2012.01.008 · 2012 · External reference
Extracellular traps (ETosis) can be activated through NADPH-dependent and -independent mechanisms in bivalve mollusks
10.1016/j.dci.2019.103585 · 2020 · External reference
Biosynthesis of 20,20,20-trifluoroleukotriene B4 from 20,20,20-trifluoroarachidonic acid: a metabolically stable analog of leukotriene B4 and its application to a study of stimulation of leukotriene B4 synthesis by immunoglobulin G1,2
10.1016/0003-9861(88)90626-1 · 1988 · External reference
Neutrophils as critical orchestrators of chronic inflammation
10.1038/s41423-025-01380-w · 2026 · External reference
Extracellular DNA traps in a ctenophore demonstrate immune cell behaviors in a non-bilaterian
10.1038/s41467-024-46807-6 · 2024 · External reference
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper
10.1016/j.fsi.2019.02.046 · 2019 · External reference
RNA chemistry and therapeutics
10.1038/s41573-025-01237-x · 2025 · External reference
Increased expression of the potential proapoptotic molecule DD2 and increased synthesis of leukotriene B4 during allograft rejection in a marine sponge
10.1038/sj.cdd.4400671 · 2000 · External reference
Hmdb 5.0: the Human Metabolome Database for 2022
10.1093/nar/gkab1062 · 2022 · External reference
Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis
10.1074/jbc.m104766200 · 2002 · External reference
Mechanistic target of rapamycin (mTOR) regulates extracellular trap production in clam Ruditapes philippinarum
10.1016/j.fsi.2026.111467 · 2026 · External reference
Various cellular responses of different shrimp haemocyte subpopulations to lipopolysaccharide stimulation
10.1016/j.fsi.2017.08.025 · 2017 · External reference
Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice
10.1182/blood-2018-05-850859 · 2018 · External reference
Different molecular responses of Mytilus mantle to lipopolysaccharide and peptidoglycan challenges
10.1016/j.fsi.2025.110246 · 2025 · External reference
Nitric oxide mediates distinct effects of various LPS chemotypes on phagocytosis and leukotriene synthesis in human neutrophils
10.1016/j.biocel.2010.01.025 · 2010 · External reference
Two paralogs of CXCR4 in the Japanese sea bass (Lateolabrax japonica) are involved in the immune response of B lymphocytes
10.1016/j.molimm.2022.01.001 · 2022 · External reference
Involvement of metabotropic glutamate receptors in regulation of immune response in the Pacific oyster Crassostrea gigas
10.1016/j.fsi.2024.109709 · 2024 · External reference
Leukotriene B4-induced neutrophil extracellular traps impede the clearance of Pneumocystis
10.1002/eji.202350779 · 2024 · External reference