Research graph
References from Atomoxetine facilitates attentional set shifting in adolescent rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression
10.1038/sj.npp.1300962 · 2006 · External reference
Trajectories of brain developnment: point of vulnerability or window of opportunity?
10.1016/s0149-7634(03)00005-8 · 2008 · External reference
Catecholamine modulation of prefrontal cortical cognitive function
10.1016/s1364-6613(98)01240-6 · 1998 · External reference
Fundamentals of attention-deficit/hyperactivity disorder: circuits and pathways
2006 · External reference
Stimulants: therapeutic actions in ADHD
10.1038/sj.npp.1301164 · 2006 · External reference
A neural circuit for circadian regulation of arousal
10.1038/89522 · 2001 · External reference
An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance
10.1146/annurev.neuro.28.061604.135709 · 2005 · External reference
Locus coeruleus and regulation of behavioral flexibility and attention
10.1016/s0079-6123(00)26013-5 · 2000 · External reference
Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD
10.1037/0033-2909.121.1.65 · 1997 · External reference
Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rats
10.1037/0735-7044.109.4.714 · 1995 · External reference
Addiction, dopamine and the molecular mechanisms of memory
10.1016/s0896-6273(00)81056-9 · 2000 · External reference
The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes
10.1016/s0165-0173(03)00143-7 · 2003 · External reference
Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function
10.1016/j.biopsych.2006.04.022 · 2006 · External reference
Efficacy of atomoxetine versus placebo in school-age girls with attention-deficit/hyperactivity disorder
10.1542/peds.110.6.e75 · 2002 · External reference
Medial frontal cortex mediates perceptual attentional set shifting in the rat
10.1523/jneurosci.20-11-04320.2000 · 2000 · External reference
Altered attention and prefrontal cortex gene expression in rats after binge-like exposure to cocaine during adolescence
10.1523/jneurosci.2391-06.2006 · 2006 · External reference
Reward expectation, orientation of attention and locus coeruleus-medial frontal cortex interplay during learning
10.1111/j.1460-9568.2004.03526.x · 2004 · External reference
Network reset: a simplified overarching theory of locus coeruleus noradrenaline function
10.1016/j.tins.2005.09.002 · 2005 · External reference
Extracellular dopamine and norepinephrine in the developing rat prefrontal cortex: transient effects of early partial loss of dopamine
10.1016/j.brainresbull.2009.01.012 · 2009 · External reference
Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults
10.1037/0735-7044.122.2.460 · 2008 · External reference
Transient D1 dopamine receptor expression on prefrontal cortex projection neurons: relationship to enhanced motivational salience of drug cues in adolescence
10.1523/jneurosci.5064-07.2008 · 2008 · External reference
Glutamate-dopamine interactions in the ventral striatum: role in locomotor activity and responding with conditioned reinforcement
10.1007/bf02245576 · 1994 · External reference
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder
10.1016/s0893-133x(02)00346-9 · 2002 · External reference
Neuroscience of attention deficit/hyperactivity disorder: the search for endophenotypes
2002 · External reference
Atomoxetine modulates right inferior frontal activation during inhibitory control: a pharmacological functional magnetic resonance imaging study
2008 · External reference
Atomoxetine improved response inhibition in adults with attention deficit/hyperactivity disorder
10.1016/j.biopsych.2007.03.003 · 2007 · External reference
Atomoxetine, a novel treatment for attention-deficit-hyperactivity disorder
10.1592/phco.24.11.1020.36146 · 2004 · External reference
Cognitive inflexibility after prefrontal serotonin depletion
10.1126/science.1094987 · 2004 · External reference
Prefrontal serotonin depletion affects reversal learning but not attentional set shifting
10.1523/jneurosci.3690-04.2005 · 2005 · External reference
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands
10.1093/cercor/11.12.1136 · 2001 · External reference
Mechanisms of cognitive set flexibility in Parkinson's disease
10.1093/brain/124.12.2503 · 2001 · External reference
Differential responses in human striatum and prefrontal cortex to changes in object and rule relevance
10.1523/jneurosci.4312-03.2004 · 2004 · External reference
Dopamine-β-hydroxylase in the rat brain: developmental characteristics
10.1111/j.1471-4159.1972.tb01354.x · 1972 · External reference
Prefrontal executive functions in rodents: neural and neurochemical substrates
10.1016/j.neubiorev.2004.09.006 · 2004 · External reference
Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and non-contingent performance of a visual attentional task
10.1523/jneurosci.21-13-04908.2001 · 2001 · External reference
A cognitive deficit induced in rats by chronic intermittent cold stress is reversed by chronic antidepressant treatment
2010 · External reference
Cognition-enhancing doses of methylphenidate preferentially increase prefrontal cortex neuronal responsiveness
10.1016/j.biopsych.2008.04.037 · 2008 · External reference
Impaired probabilistic reversal learning in youths with mood and anxiety disorders
10.1017/s0033291709991462 · 2009 · External reference
Methylphenidate improves performance on the radial arm in periadolescent rats
10.1016/j.ntt.2008.04.001 · 2008 · External reference
Decision making in adolescents with behavior disorders and adults with substance abuse
10.1176/appi.ajp.160.1.33 · 2003 · External reference
Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning
10.1001/archpsyc.65.5.586 · 2008 · External reference
Methylphenidate and atomoxetine enhance prefrontal function through α2-adrenergic and dopamine D1 receptors
10.1016/j.jaac.2010.06.015 · 2010 · External reference
Attention deficit hyperactivity disorder across the lifespan: the child, adolescent, and adult
10.1016/j.disamonth.2007.01.001 · 2007 · External reference
Ontogeny of B -adrenergic receptors in rat cerebral cortex
10.1016/0006-8993(77)90362-6 · 1977 · External reference
Operant performance and cortical acetylcholine release: role of response rate, reward density, and non-contingent stimuli
10.1016/s0926-6410(97)00014-1 · 1997 · External reference
Increases in cortical acetylcholine release during sustained attention performance in rats
10.1016/s0926-6410(00)00012-4 · 2000 · External reference
The effects of manipulations of attentional demand on cortical acetylcholine release
10.1016/s0926-6410(01)00064-7 · 2001 · External reference
Association studies of −3081(A/T) polymorphism of norepinephrine transporter gene with attention deficit/hyperactivity disorder in Korean population
10.1002/ajmg.b.31012 · 2009 · External reference
Neurobiology of attention deficit hyperactivity disorder
10.1016/j.chc.2007.11.012 · 2008 · External reference
Atomoxetine: a selective noradrenergic reuptake inhibitor for the treatment of attention-deficit/hyperactivity disorder
10.1517/14656566.4.7.1165 · 2003 · External reference
Effects of long-term atomoxetine treatment for young children with attention-deficit/hyperactivity disorder
10.1097/01.chi.0000222788.34229.68 · 2006 · External reference
Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine
10.1523/jneurosci.22-16-07264.2002 · 2002 · External reference
Effects of reward and response costs on inhibition in ADHD children
10.1037/0021-843x.104.1.232 · 1995 · External reference
Differential postnatal development of catecholamine and serotonin inputs to identified neurons in prefrontal cortex of rhesus monkey
10.1523/jneurosci.20-23-08780.2000 · 2000 · External reference
Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats
10.1007/s00213-008-1224-6 · 2009 · External reference
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test
10.1038/sj.npp.1301235 · 2007 · External reference
Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability
10.1016/j.neuroscience.2005.09.031 · 2006 · External reference
Psychobiological risk factors for vulnerability to psychostimulants in human adolescents and animal models
10.1016/s0149-7634(99)00032-9 · 1999 · External reference
Development of the noradrenergic innervation of the neocortex
10.1016/0006-8993(79)90287-7 · 1979 · External reference
Fronto-limbic functioning in children and adolescents with and without autism
10.1016/j.neuropsychologia.2007.08.017 · 2008 · External reference
Orbital prefrontal cortex mediates reversal learning and not attentional set-shifting
10.1016/j.bbr.2003.09.019 · 2003 · External reference
Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a 5 choice serial reaction time task
10.1523/jneurosci.22-05-01905.2002 · 2002 · External reference
Behavioral vigilance following infusions of 192 IgG-saporin into the basal forebrain: selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density
10.1037/0735-7044.110.2.247 · 1996 · External reference
Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting
10.1016/j.neuroscience.2008.01.064 · 2008 · External reference
Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain
10.1523/jneurosci.20-06-j0004.2000 · 2000 · External reference
Selective depletion of cortical noradrenaline by anti-dopamine beta-hydroxylase impairs attentional function and enhances the effects of guanfacine in the rat
10.1007/s00213-006-0594-x · 2007 · External reference
Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood
10.1016/s0165-3806(99)00182-0 · 2000 · External reference
Noradrenergic innervation patterns in three regions of medial cortex: an immunofluorescence characterization
10.1016/0361-9230(79)90022-4 · 1979 · External reference
The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers
10.1007/s00213-002-1128-9 · 2002 · External reference
Comparison of the maturation of the adrenergic and serotonergic neurotransmitter systems in the brain: implications for differential drug effects on juveniles and adults
10.1016/j.bcp.2007.01.028 · 2007 · External reference
Atomoxetine and osmotically released methylphenidate for the treatment of attention deficit hyperactivity disorder: acute comparison and differential response
10.1176/appi.ajp.2007.05091676 · 2008 · External reference
Atomoxetine reverses attentional deficits produced by noradrenergic deafferentation of medial prefrontal cortex
10.1007/s00213-008-1097-8 · 2008 · External reference
Adolescent rats show cognitive rigidity in a test of attentional set shifting
10.1002/dev.20537 · 2011 · External reference
Prefrontal acetylcholine release controls cue detection on multiple time scales
10.1016/j.neuron.2007.08.025 · 2007 · External reference
Early life stress and novelty seeking behavior in adolescent monkeys
10.1016/j.psyneuen.2007.05.008 · 2007 · External reference
Chemical neuromodulation of frontal-executive functions in humans and other animals
10.1007/s002210000407 · 2000 · External reference
Drug addiction: bad habits add up
10.1038/19208 · 1999 · External reference
Executive cognitive functions and impulsivity as correlates of risk taking and problem behavior in preadolescents
10.1016/j.neuropsychologia.2009.06.019 · 2009 · External reference
Attention deficit/hyperactivity disorder-from branin dysfuncitons to behaviour
1998 · External reference
Development of the norepinephrine transporter in the rat CNS
10.1016/j.neuroscience.2004.09.014 · 2005 · External reference
Unraveling the attentional functions of cortical cholinergic inputs: interactions between signal-driven and cognitive modulation of signal detection
10.1016/j.brainresrev.2004.08.006 · 2005 · External reference
Differential prefrontal cortex activation during inhibitory control in adolescents with and without childhood attention-deficit/hyperactivity disorder
10.1037/0894-4105.19.3.390 · 2005 · External reference
Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys
10.1007/s00213-008-1250-4 · 2008 · External reference
The effects of methylphenidate on neural systems of attention in attention deficit hyperactivity disorder
10.1176/appi.ajp.161.11.1990 · 2004 · External reference
Neuropharmacological basis of stimulant drug action in attention deficit disorder with hyperactivity: a review and synthesis
10.1037/0033-2909.95.3.387 · 1984 · External reference
Executive dysfunction and delay aversion in attention deficit hyperactivity disorder: nosologic and diagnostic implications
10.1016/j.chc.2007.11.008 · 2008 · External reference
Effectiveness and tolerability of tomoxetine in adults with attention deficit hyperactivity disorder
10.1176/ajp.155.5.693 · 1998 · External reference
Lesions of the dorsal noradrenergic bundle impair attentional set shifting in the rat
10.1111/j.1460-9568.2007.05612.x · 2007 · External reference
The orbitofrontal cortex and ventral tegmental area are necessary for learning from unexpected outcomes
10.1016/j.neuron.2009.03.005 · 2009 · External reference
Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine
10.1038/sj.mp.4001763 · 2007 · External reference
The role of locus coeruleus in the regulation of cognitive performance
10.1126/science.283.5401.549 · 1999 · External reference
Distribution of the catecholaminergic neurons in the central nervous system of human embryos and fetuses
10.1002/(sici)1097-0029(19990701)46:1<24::aid-jemt3>3.0.co;2-e · 1999 · External reference
Dysfunction in dopamine systems and ADHD: evidence from animals and modeling
10.1155/np.2004.97 · 2004 · External reference
The involvement of the noradrenergic system arising from the locus coeruleus in the postnatal development of the cortex in rat brain
10.1016/0006-8993(77)90355-9 · 1977 · External reference
A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain
10.1016/s0022-3565(25)33153-8 · 1982 · External reference
Replication of a rare protective allele in the noradrenaline transporter gene and ADHD
10.1002/ajmg.b.30872 · 2008 · External reference
Uncertainty neuromodulation and attention
10.1016/j.neuron.2005.04.026 · 2005 · External reference