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References from Development of the motivational system during adolescence, and its sensitivity to disruption by nicotine. Local targets link to admitted publications; unresolved targets remain external evidence.
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The role of CYP2A6 in the emergence of nicotine dependence in adolescents
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Age-dependent effects of nicotine on locomotor activity and conditioned place preference in rats
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Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats
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Myelination of cortical-hippocampal relays during late adolescence
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Evidence that tobacco smoking increases the density of (-)-[3H]nicotine binding sites in human brain
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Impulsivity and cigarette smoking: delay discounting in current, never, and ex-smokers
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Synaptogenesis in the prefrontal cortex of rhesus monkeys
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Effect of smoking history on [3H]nicotine binding in human postmortem brain
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Delayed extinction and stronger reinstatement of cocaine conditioned place preference in adolescent rats, compared to adults
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Immediate and long-term behavioral effects of a single nicotine injection in adolescent and adult rats
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Drug use and the risk of major depressive disorder, alcohol dependence, and substance use disorders
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Which adolescent experimenters progress to established smoking in the United States
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Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence
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Changes in molecular composition of rat medial prefrontal cortex synapses during adolescent development
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Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats
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Increasing Interaction of amygdalar afferents with GABAergic interneurons between birth and adulthood
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Delay discounting predicts cigarette smoking in a laboratory model of abstinence reinforcement
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A survey of adolescent smoking patterns
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Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats
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Recollections and repercussions of the first inhaled cigarette
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Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure
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Effect of subtype selective nicotinic compounds on attention as assessed by the five-choice serial reaction time task
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Nicotine use and dependence and their association to psychiatric disorders in a large sample of adolescent psychiatric inpatients
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Synaptic activity-dependent developmental regulation of NMDA receptor subunit expression in cultured neocortical neurons
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Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat
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Mechanisms of eye-specific visual circuit development
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Synaptic density in human frontal cortex - developmental changes and effects of aging
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Morphometric study of human cerebral cortex development
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Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers
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Maturation of human cerebrum observed in vivo during adolescence
10.1093/brain/114.5.2037 · 1991 · External reference
Developmental expression, subcellular localization, and tyrosine phosphorylation of NR2A and NR2B in the rat brain
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Inhalants to heroin: a prospective analysis from adolescence to adulthood
10.1016/0376-8716(95)01201-x · 1995 · External reference
Association between cigarette smoking and anxiety disorders during adolescence and early adulthood
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Metabotropic glutamate receptors mGluR1alpha and mGluR2/3 display dynamic expression patterns in developing rat striatum
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Development of the dopaminergic innervation in the prefrontal cortex of the rat
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Stages in adolescent involvement in drug use
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Extent of smoking and nicotine dependence in the United States: 1991–1993
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Stages of progression in drug involvement from adolescence to adulthood: further evidence for the gateway theory
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Behavioral consequences of repeated nicotine during adolescence in alcohol-preferring AA and alcohol-avoiding ANA rats
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Depressive symptoms and cigarette smoking in a college sample
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Development of the cholinergic fibres innervating the cerebral cortex of the rat
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Development of a superior frontal-intraparietal network for visuo-spatial working memory
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Enhanced nicotine reward in adulthood after exposure to nicotine during early adolescence in mice
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Behavioral impulsivity predicts treatment outcome in a smoking cessation program for adolescent smokers
10.1016/j.drugalcdep.2006.09.006 · 2007 · External reference
Calcium-dependent inactivation of recombinant N-methyl-D-aspartate receptors is NR2 subunit specific
10.1016/s0026-895x(25)09630-0 · 1996 · External reference
Roles of accessory subunits in alpha4beta2(*) nicotinic receptors
10.1124/mol.108.046789 · 2008 · External reference
Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice
10.1124/mol.104.006429 · 2005 · External reference
Communication in neuronal networks
10.1126/science.1089662 · 2003 · External reference
A functional magnetic resonance imaging (FMRI) study of cue-induced smoking craving in virtual environments
10.1007/s10484-005-6377-z · 2005 · External reference
Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates
10.1016/j.ntt.2007.02.002 · 2007 · External reference
Adolescent-onset nicotine self-administration modeled in female rats
10.1007/s00213-003-1486-y · 2003 · External reference
Level of current and past adolescent cigarette smoking as predictors of future substance use disorders in young adulthood
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Synapse elimination and indelible memory
10.1016/s0896-6273(00)80893-4 · 2000 · External reference
Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits
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Nicotinic modulation of neuronal networks: from receptors to cognition
10.1007/s00213-005-0070-z · 2006 · External reference
Neuron number decreases in the rat ventral, but not dorsal, medial prefrontal cortex between adolescence and adulthood
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Effects of chronic nicotine infusion on tolerance development and nicotinic receptors
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Age matters
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A longitudinal study of cannabis use and mental health from adolescence to early adulthood
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Low dose nicotine treatment during early adolescence increases subsequent cocaine reward
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Myelination in the hippocampus during development and following lesion
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Measures of impulsivity in cigarette smokers and non-smokers
10.1007/pl00005491 · 1999 · External reference
[123I]5-IA-85380 SPECT imaging of beta2-nicotinic acetylcholine receptor availability in the aging human brain
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A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes
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Selective down-regulation of [(125)I]Y0-alpha-conotoxin MII binding in rat mesostriatal dopamine pathway following continuous infusion of nicotine
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Smoking impacts on prefrontal attentional network function in young adult brains
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Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path
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A psychobiological framework of the substrates that mediate nicotine use during adolescence
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Nicotine withdrawal in adolescent and adult rats
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Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction
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Rodent models of nicotine reward: what do they tell us about tobacco abuse in humans?
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Adolescent nicotine exposure produces less affective measures of withdrawal relative to adult nicotine exposure in male rats
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Strain specificity and cholinergic modulation of visuospatial attention in three inbred mouse strains
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The neuropharmacology of impulsive behaviour
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Mapping brain maturation and cognitive development during adolescence
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Structural maturation of neural pathways in children and adolescents: in vivo study
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Smoking, nicotine dependence and mental health among young adults: a 13-year population-based longitudinal study
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Nicotine withdrawal symptoms in adolescent and adult twins
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Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies
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Chronic nicotine differentially regulates alpha6- and beta3-containing nicotinic cholinergic receptors in rat brain
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Effects of transdermal nicotine on attention in adult non-smokers with and without attentional deficits
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Measuring nicotine dependence among high-risk adolescent smokers
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10.1002/cne.903580306 · 1995 · External reference
Smoking-related cue-induced brain activation in adolescent light smokers
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Nicotine self-administration, extinction responding and reinstatement in adolescent and adult male rats: evidence against a biological vulnerability to nicotine addiction during adolescence
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Interactions between age and the aversive effects of nicotine withdrawal under mecamylamine-precipitated and spontaneous conditions in male Wistar rats
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Impulsivity in smoking, nonsmoking, and ex-smoking alcoholics
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Increased anxiety-like behavior in adult rats exposed to nicotine as adolescents
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Increased CRF-like and NPY-like immunoreactivity in adult rats exposed to nicotine during adolescence: relation to anxiety-like and depressive-like behavior
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Long-term changes in fear conditioning and anxiety-like behavior following nicotine exposure in adult versus adolescent rats
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Nicotine patch therapy in adolescent smokers
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Diffusion tensor imaging of neurodevelopment in children and young adults
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Mapping continued brain growth and gray matter density reduction in dorsal frontal cortex: inverse relationships during postadolescent brain maturation
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The adolescent brain and age-related behavioral manifestations
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Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development
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Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions
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D2 dopamine receptors recruit a GABA component for their attenuation of excitatory synaptic transmission in the adult rat prefrontal cortex
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Beta3 subunits promote expression and nicotine-induced up-regulation of human nicotinic alpha6* nicotinic acetylcholine receptors expressed in transfected cell lines
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Unresolved reference
2003 · External reference
Heterotopic cortical afferents to the medial prefrontal cortex in the rat. A combined retrograde and anterograde tracer study
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Behavioral disinhibition requires dopamine receptor activation
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Nicotine-induced conditioned place preference in adolescent and adult rats
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The association of current smoking behavior with the smoking behavior of parents, siblings, friends and spouses
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Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex
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Unresolved reference
External reference
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Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice
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Sensitivity to cocaine conditioned reward depends on sex and age
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