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Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

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G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

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The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network

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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

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Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

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ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

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Mammalian IRE1α dynamically and functionally coalesces with stress granules

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Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases

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Calcium signaling from damaged lysosomes induces cytoprotective stress granules

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Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules

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Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

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ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

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RNA damage compartmentalization by DHX9 stress granules

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Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress

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Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD

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Listerin promotes cGAS protein degradation through the ESCRT pathway to negatively regulate cGAS-mediated immune response

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Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage

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G3BP1 promotes DNA binding and activation of cGAS

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TIA1-Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL-31RA Signaling

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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells

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TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

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Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling

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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits

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Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition

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Yin and yang regulation of stress granules by Caprin-1

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TRIM25 predominately associates with anti-viral stress granules

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ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

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Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly

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Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

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Efficient proximity labeling in living cells and organisms with TurboID

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