Research graph
References from Quantification of total T4, T3, and reverse T3 in canine serum using UPLC-MS/MS: Analytical validation, reference intervals, and method comparison with traditional chemiluminescence immunoassays. Local targets link to admitted publications; unresolved targets remain external evidence.
Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK
10.1186/s40575-022-00123-8 · 2022 · External reference
Epidemiological, clinical, haematological and biochemical characteristics of canine hypothyroidism
10.1136/vr.145.17.481 · 1999 · External reference
Hypothyroidism in dogs: 66 cases (1987-1992)
10.2460/javma.1994.204.05.761 · 1994 · External reference
10.3390/vetsci13010035
10.3390/vetsci13010035 · 2026 · External reference
Unresolved reference
2004 · External reference
Testing for hypothyroidism in dogs
10.1016/j.cvsm.2007.05.015 · 2007 · External reference
2024 European Thyroid Association guidelines on diagnosis and management of genetic disorders of thyroid hormone transport, metabolism and action
2024 · External reference
2022 European Thyroid Association guideline for the management of pediatric Graves’ disease
2022 · External reference
LT4/LT3 Combination therapy vs. Monotherapy with LT4 for persistent symptoms of hypothyroidism: a systematic review
10.3390/ijms25179218 · 2024 · External reference
Diagnosis of canine hypothyroidism. Perspectives from a testing laboratory
10.1016/s0195-5616(01)50007-8 · 2001 · External reference
Development and evaluation of a reference measurement procedure for the determination of total 3,3¢,5-triiodothyronine in Human serum using isotope-dilution liquid chromatography-tandem mass spectrometry
10.1021/ac049516h · 2004 · External reference
A mass spectrometry-based panel of nine thyroid hormone metabolites in Human serum
10.1093/clinchem/hvaa022 · 2020 · External reference
Mass spectrometry-based determination of thyroid hormones and their metabolites in endocrine diagnostics and biomedical research - implications for Human serum diagnostics
2020 · External reference
Determination of free thyroid hormones in animal serum/plasma using ultrafiltration in combination with ultra-fast liquid chromatography-tandem mass spectrometry
10.1016/j.chroma.2018.01.044 · 2018 · External reference
10.3390/ani15050689
10.3390/ani15050689 · External reference
Reverse triiodothyronine concentrations in hyperthyroid, healthy, and azotemic cats determined by ultra-performance liquid chromatography-tandem mass spectrometry
10.1016/j.domaniend.2025.106956 · 2025 · External reference
Comparison of 2 assays for measuring serum total thyroxine concentration in dogs and cats
10.1111/jvim.15703 · 2020 · External reference
Comparison of the Vcheck and IMMULITE 2000 methods for T4 measurement in canine and feline serum
2022 · External reference
Unresolved reference
External reference
Laboratory indicators of hypothyroidism and TgAA-positivity in the Eurasian dog breed
10.1371/journal.pone.0280906 · 2023 · External reference
Total thyroxine, triiodothyronine, and thyrotropin concentrations during acute nonthyroidal illness and recovery in dogs
10.1111/jvim.17059 · 2024 · External reference
Reference Value Advisor: a new freeware set of macroinstructions to calculate reference intervals with Microsoft Excel
10.1111/j.1939-165x.2011.00287.x · 2011 · External reference
refineR: a novel algorithm for reference interval estimation from real-world data
10.1038/s41598-021-95301-2 · 2021 · External reference
Correlation between serum levels of 3,3′,5′-triiodothyronine and thyroid hormones measured by liquid chromatography-tandem mass spectrometry and immunoassay
10.1371/journal.pone.0138864 · 2015 · External reference
Candidate reference method for total thyroxine in human serum: use of isotope-dilution liquid chromatography-mass spectrometry with electrospray ionization
10.1093/clinchem/48.4.637 · 2002 · External reference
Development and evaluation of a reference measurement procedure for the determination of total 3,3′,5-triiodothyronine in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry
10.1021/ac049516h · 2004 · External reference
Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry
10.1007/s00216-010-3705-9 · 2010 · External reference
Determination of six thyroid hormones in dog brain and liver using acidic extraction, mixed-mode cleanup, and liquid chromatography-tandem mass spectrometry
10.1016/j.chroma.2021.462686 · 2022 · External reference
Unresolved reference
2019 · External reference
ASVCP. ASVCP guidelines: allowable total error guidelines for biochemistry
10.1111/vcp.12101 · 2013 · External reference
Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs
10.2460/javma.1997.211.11.1396 · 1997 · External reference
Effect of time of sample collection on serum thyroid-stimulating hormone concentrations in euthyroid and hypothyroid dogs
10.2460/javma.1998.212.10.1572 · 1998 · External reference
Circadian variations of serum thyroxine, free thyroxine and 3,5,3′triiodothyronine concentrations in healthy dogs
10.4142/jvs.2006.7.1.25 · 2006 · External reference
A plea for intra-laboratory reference limits. Part 1. General considerations and concepts for determination
10.1515/cclm.2007.249 · 2007 · External reference
Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia
10.1016/j.vetpar.2015.04.023 · 2015 · External reference
Analytic bias of thyroid function tests: analysis of a College of American Pathologists fresh frozen serum pool by 3900 clinical laboratories
10.5858/2005-129-310-abotft · 2005 · External reference
Isotope dilution tandem mass spectrometric method for T4/T3
10.1016/j.cccn.2004.01.007 · 2004 · External reference
Effects of propranolol on thyroid function in the dog
10.2460/ajvr.1984.45.01.109 · 1984 · External reference
Effect of endotoxin on hormonal responses to thyrotropin and thyrotropin-releasing hormone in dogs
10.2460/ajvr.1998.59.02.186 · 1998 · External reference
Serum free and total iodothyronine concentrations in dogs with hyperadrenocorticism
10.2460/ajvr.1992.53.09.1636 · 1992 · External reference
Effects of oral administration of anti-inflammatory doses of prednisone on thyroid hormone response to thyrotropin-releasing hormone and thyrotropin in clinically normal dogs
10.2460/ajvr.1993.54.01.130 · 1993 · External reference
Thyroid function in dogs with spontaneous and induced congestive heart failure
1994 · External reference
Evaluation of the effects of clomipramine on canine thyroid function tests
10.1111/j.1939-1676.2003.tb01322.x · 2003 · External reference
Endotoxin-induced nonthyroidal illness in dogs
10.2460/ajvr.2003.64.229 · 2003 · External reference
Evaluation of thyroid function in obese dogs and in dogs undergoing a weight loss protocol
10.1046/j.1439-0442.2003.00534.x · 2003 · External reference
Assessment of criteria used by veterinary practitioners to diagnose hypothyroidism in sighthounds and investigation of serum thyroid hormone concentrations in healthy Salukis
10.2460/javma.236.3.302 · 2010 · External reference
Breed-specific reference intervals for assessing thyroid function in seven dog breeds
10.1177/1040638715606953 · 2015 · External reference
Relationship between thyroid function and sex hormones in female German shepherd dogs
10.1111/jvim.16959 · 2024 · External reference
American Society for Veterinary Clinical Pathology. ASVCP reference interval guidelines: determination of de novo reference intervals in veterinary species and other related topics
10.1111/vcp.12006 · 2012 · External reference
Thyroid function testing in Greyhounds
10.2460/ajvr.2001.62.1130 · 2001 · External reference
Thyroid hormone concentrations in young, healthy, pretraining greyhounds
10.1136/vr.161.18.616 · 2007 · External reference
Serum thyroid hormone concentrations and thyroglobulin autoantibodies in trained and non-trained healthy whippets
10.1016/j.tvjl.2005.03.007 · 2006 · External reference
Thyroid testing in Sloughis
10.1111/j.1939-1676.2008.0155.x · 2008 · External reference
Evaluation of the thyroid status of Basenji dogs in Australia
10.1111/j.1751-0813.2008.00357.x · 2008 · External reference
Clinical pathology of greyhounds and other sighthounds
10.1111/j.1939-165x.2011.00360.x · 2011 · External reference
Breed-specific biochemical reference intervals for the adult Dogue de Bordeaux
10.1111/vcp.12067 · 2013 · External reference
Haematological and biochemical values in North American Scottish deerhounds
10.1111/jsap.12086 · 2013 · External reference
QimmeqHealth-thyroid status of Greenland sled dogs (Canis lupus familiaris borealis)
10.1186/s13028-021-00617-8 · 2021 · External reference
Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry
10.1007/s00216-010-3705-9 · ExternalCitation · doi-reference
Isotope dilution tandem mass spectrometric method for T4/T3
10.1016/j.cccn.2004.01.007 · ExternalCitation · doi-reference
Determination of free thyroid hormones in animal serum/plasma using ultrafiltration in combination with ultra-fast liquid chromatography-tandem mass spectrometry
10.1016/j.chroma.2018.01.044 · ExternalCitation · doi-reference
Determination of six thyroid hormones in dog brain and liver using acidic extraction, mixed-mode cleanup, and liquid chromatography-tandem mass spectrometry
10.1016/j.chroma.2021.462686 · ExternalCitation · doi-reference
Testing for hypothyroidism in dogs
10.1016/j.cvsm.2007.05.015 · ExternalCitation · doi-reference
Reverse triiodothyronine concentrations in hyperthyroid, healthy, and azotemic cats determined by ultra-performance liquid chromatography-tandem mass spectrometry
10.1016/j.domaniend.2025.106956 · ExternalCitation · doi-reference
Serum thyroid hormone concentrations and thyroglobulin autoantibodies in trained and non-trained healthy whippets
10.1016/j.tvjl.2005.03.007 · ExternalCitation · doi-reference
Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia
10.1016/j.vetpar.2015.04.023 · ExternalCitation · doi-reference
Diagnosis of canine hypothyroidism. Perspectives from a testing laboratory
10.1016/s0195-5616(01)50007-8 · ExternalCitation · doi-reference
Development and evaluation of a reference measurement procedure for the determination of total 3,3′,5-triiodothyronine in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry
10.1021/ac049516h · ExternalCitation · doi-reference
refineR: a novel algorithm for reference interval estimation from real-world data
10.1038/s41598-021-95301-2 · ExternalCitation · doi-reference
Evaluation of thyroid function in obese dogs and in dogs undergoing a weight loss protocol
10.1046/j.1439-0442.2003.00534.x · ExternalCitation · doi-reference
Candidate reference method for total thyroxine in human serum: use of isotope-dilution liquid chromatography-mass spectrometry with electrospray ionization
10.1093/clinchem/48.4.637 · ExternalCitation · doi-reference
A mass spectrometry-based panel of nine thyroid hormone metabolites in Human serum
10.1093/clinchem/hvaa022 · ExternalCitation · doi-reference
Evaluation of the thyroid status of Basenji dogs in Australia
10.1111/j.1751-0813.2008.00357.x · ExternalCitation · doi-reference
Reference Value Advisor: a new freeware set of macroinstructions to calculate reference intervals with Microsoft Excel
10.1111/j.1939-165x.2011.00287.x · ExternalCitation · doi-reference
Clinical pathology of greyhounds and other sighthounds
10.1111/j.1939-165x.2011.00360.x · ExternalCitation · doi-reference
Evaluation of the effects of clomipramine on canine thyroid function tests
10.1111/j.1939-1676.2003.tb01322.x · ExternalCitation · doi-reference
Thyroid testing in Sloughis
10.1111/j.1939-1676.2008.0155.x · ExternalCitation · doi-reference
Haematological and biochemical values in North American Scottish deerhounds
10.1111/jsap.12086 · ExternalCitation · doi-reference
Comparison of 2 assays for measuring serum total thyroxine concentration in dogs and cats
10.1111/jvim.15703 · ExternalCitation · doi-reference
Relationship between thyroid function and sex hormones in female German shepherd dogs
10.1111/jvim.16959 · ExternalCitation · doi-reference
Total thyroxine, triiodothyronine, and thyrotropin concentrations during acute nonthyroidal illness and recovery in dogs
10.1111/jvim.17059 · ExternalCitation · doi-reference
American Society for Veterinary Clinical Pathology. ASVCP reference interval guidelines: determination of de novo reference intervals in veterinary species and other related topics
10.1111/vcp.12006 · ExternalCitation · doi-reference
Breed-specific biochemical reference intervals for the adult Dogue de Bordeaux
10.1111/vcp.12067 · ExternalCitation · doi-reference
ASVCP. ASVCP guidelines: allowable total error guidelines for biochemistry
10.1111/vcp.12101 · ExternalCitation · doi-reference
Epidemiological, clinical, haematological and biochemical characteristics of canine hypothyroidism
10.1136/vr.145.17.481 · ExternalCitation · doi-reference
Thyroid hormone concentrations in young, healthy, pretraining greyhounds
10.1136/vr.161.18.616 · ExternalCitation · doi-reference
Breed-specific reference intervals for assessing thyroid function in seven dog breeds
10.1177/1040638715606953 · ExternalCitation · doi-reference
QimmeqHealth-thyroid status of Greenland sled dogs (Canis lupus familiaris borealis)
10.1186/s13028-021-00617-8 · ExternalCitation · doi-reference
Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK
10.1186/s40575-022-00123-8 · ExternalCitation · doi-reference
Correlation between serum levels of 3,3′,5′-triiodothyronine and thyroid hormones measured by liquid chromatography-tandem mass spectrometry and immunoassay
10.1371/journal.pone.0138864 · ExternalCitation · doi-reference
Laboratory indicators of hypothyroidism and TgAA-positivity in the Eurasian dog breed
10.1371/journal.pone.0280906 · ExternalCitation · doi-reference
A plea for intra-laboratory reference limits. Part 1. General considerations and concepts for determination
10.1515/cclm.2007.249 · ExternalCitation · doi-reference
Effects of propranolol on thyroid function in the dog
10.2460/ajvr.1984.45.01.109 · ExternalCitation · doi-reference
Serum free and total iodothyronine concentrations in dogs with hyperadrenocorticism
10.2460/ajvr.1992.53.09.1636 · ExternalCitation · doi-reference
Effects of oral administration of anti-inflammatory doses of prednisone on thyroid hormone response to thyrotropin-releasing hormone and thyrotropin in clinically normal dogs
10.2460/ajvr.1993.54.01.130 · ExternalCitation · doi-reference
Effect of endotoxin on hormonal responses to thyrotropin and thyrotropin-releasing hormone in dogs
10.2460/ajvr.1998.59.02.186 · ExternalCitation · doi-reference
Thyroid function testing in Greyhounds
10.2460/ajvr.2001.62.1130 · ExternalCitation · doi-reference
Endotoxin-induced nonthyroidal illness in dogs
10.2460/ajvr.2003.64.229 · ExternalCitation · doi-reference
Hypothyroidism in dogs: 66 cases (1987-1992)
10.2460/javma.1994.204.05.761 · ExternalCitation · doi-reference
Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs
10.2460/javma.1997.211.11.1396 · ExternalCitation · doi-reference
Effect of time of sample collection on serum thyroid-stimulating hormone concentrations in euthyroid and hypothyroid dogs
10.2460/javma.1998.212.10.1572 · ExternalCitation · doi-reference
Assessment of criteria used by veterinary practitioners to diagnose hypothyroidism in sighthounds and investigation of serum thyroid hormone concentrations in healthy Salukis
10.2460/javma.236.3.302 · ExternalCitation · doi-reference
10.3390/ani15050689
10.3390/ani15050689 · ExternalCitation · doi-reference
LT4/LT3 Combination therapy vs. Monotherapy with LT4 for persistent symptoms of hypothyroidism: a systematic review
10.3390/ijms25179218 · ExternalCitation · doi-reference
10.3390/vetsci13010035
10.3390/vetsci13010035 · ExternalCitation · doi-reference
Circadian variations of serum thyroxine, free thyroxine and 3,5,3′triiodothyronine concentrations in healthy dogs
10.4142/jvs.2006.7.1.25 · ExternalCitation · doi-reference
Analytic bias of thyroid function tests: analysis of a College of American Pathologists fresh frozen serum pool by 3900 clinical laboratories
10.5858/2005-129-310-abotft · ExternalCitation · doi-reference
