Research graph
References from Integrated multi-omics and experimental analyses reveal VIPR1 as a potential mediator linking environmental bisphenol A exposure to MASH-HCC progression. Local targets link to admitted publications; unresolved targets remain external evidence.
Environmental pollutants, occupational exposures, and liver disease
10.1055/a-2540-2861 · 2025 · External reference
beta-Arrestin-independent endosomal cAMP signaling by a polypeptide hormone GPCR
10.1038/s41589-023-01412-4 · 2024 · External reference
VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins
10.1111/j.1476-5381.2011.01676.x · 2012 · External reference
Unveiling the ESR1 dysfunction orchestrates the link per- and polyfluoroalkyl substances exposure to osteoarthritis: Insights from multi-scale evidence
10.1016/j.ecoenv.2025.119538 · 2026 · External reference
The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan
10.1007/s00535-020-01748-x · 2021 · External reference
Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030
10.1016/j.jhep.2018.05.036 · 2018 · External reference
The role of Aurora kinase A in hepatocellular carcinoma: Unveiling the intriguing functions of a key but still underexplored factor in liver cancer
10.1111/cpr.13641 · 2024 · External reference
MASLD and MASLD-associated HCC: emerging biomarkers and therapeutic avenues
10.1016/j.scib.2026.04.048 · 2026 · External reference
Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma
10.1124/jpet.118.255018 · 2019 · External reference
Worldwide burden of liver cancer due to metabolic dysfunction-associated steatohepatitis from 1990 to 2019: insights from the Global Burden of Disease study
2024 · External reference
Targeting RBM39 with Tasisulam enhances TRAIL-induced apoptosis through DR5 upregulation and Bcl-2 downregulation in renal cell carcinoma
10.1016/j.bcp.2025.116877 · 2025 · External reference
The maximal affinity of ligands
10.1073/pnas.96.18.9997 · 1999 · External reference
VIPR1 acts as an enteric neural checkpoint that suppresses intestinal stem cell-driven epithelial regeneration and exacerbates colitis
10.1016/j.stem.2026.01.009 · 2026 · External reference
Bisphenols exposure and non-alcoholic fatty liver disease: from environmental trigger to molecular pathogenesis
2025 · External reference
Mapping the association between environmental pollutants and steatotic liver disease: a systematic review and meta-analysis
2025 · External reference
Multi omics analysis reveals senescence associated genes in metabolic dysfunction associated steatohepatitis related liver cancer and their functional validation
10.1016/j.ijbiomac.2026.151713 · 2026 · External reference
Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization
10.1158/1535-7163.mct-11-0323 · 2011 · External reference
Human exposure to Bisphenol A and liver health status: Quantification of urinary and circulating levels by LC-MS/MS
10.1016/j.jpba.2017.02.058 · 2017 · External reference
Integrating network toxicology and experimental validation to elucidate the molecular mechanism basis of chondrotoxicity of Benzo[a]pyrene in osteoarthritis
10.1016/j.ecoenv.2026.120177 · 2026 · External reference
Systematic review of the potential carcinogenicity of bisphenol A in humans
10.1016/j.yrtph.2023.105414 · 2023 · External reference
Global burden of primary liver cancer in 2020 and predictions to 2040
10.1016/j.jhep.2022.08.021 · 2022 · External reference
Bisphenol A Alters the Expression of Genes Involved in Lipogenesis, Inflammation, and Oxidative Stress in the Liver of Adult Zebrafish
2025 · External reference
Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring
10.1038/s42255-024-01019-6 · 2024 · External reference
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 · External reference
Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A
10.1590/s1413-81232012000200015 · 2012 · External reference
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development
10.20892/j.issn.2095-3941.2019.0335 · 2020 · External reference
Mechanistic exploration of bisphenol A in primary Sjogren's syndrome using network toxicology, molecular docking, molecular dynamics simulations and experimental validation
10.1186/s40360-025-01070-3 · 2025 · External reference
Stat3 is a candidate epigenetic biomarker of perinatal Bisphenol A exposure associated with murine hepatic tumors with implications for human health
10.1080/15592294.2015.1107694 · 2015 · External reference
Multiscale identification of DNASE1L3 as a key target in MASLD progression to hepatocellular carcinoma
10.1016/j.prp.2025.156192 · 2025 · External reference
First evidence in the association of phenolic endocrine-disrupting chemicals with secondary non-alcoholic fatty liver disease: A case-control study in South China
10.1016/j.envpol.2025.126086 · 2025 · External reference
Tumor microenvironment and metabolic reprogramming in MASLD-related hepatocellular carcinoma
10.1016/j.molmed.2026.04.010 · 2026 · External reference
The role of vasoactive intestinal peptide in pulmonary diseases
10.1016/j.lfs.2023.122121 · 2023 · External reference
The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan
10.1007/s00535-020-01748-x · ExternalCitation · doi-reference
Targeting RBM39 with Tasisulam enhances TRAIL-induced apoptosis through DR5 upregulation and Bcl-2 downregulation in renal cell carcinoma
10.1016/j.bcp.2025.116877 · ExternalCitation · doi-reference
Unveiling the ESR1 dysfunction orchestrates the link per- and polyfluoroalkyl substances exposure to osteoarthritis: Insights from multi-scale evidence
10.1016/j.ecoenv.2025.119538 · ExternalCitation · doi-reference
Integrating network toxicology and experimental validation to elucidate the molecular mechanism basis of chondrotoxicity of Benzo[a]pyrene in osteoarthritis
10.1016/j.ecoenv.2026.120177 · ExternalCitation · doi-reference
First evidence in the association of phenolic endocrine-disrupting chemicals with secondary non-alcoholic fatty liver disease: A case-control study in South China
10.1016/j.envpol.2025.126086 · ExternalCitation · doi-reference
Multi omics analysis reveals senescence associated genes in metabolic dysfunction associated steatohepatitis related liver cancer and their functional validation
10.1016/j.ijbiomac.2026.151713 · ExternalCitation · doi-reference
Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030
10.1016/j.jhep.2018.05.036 · ExternalCitation · doi-reference
Global burden of primary liver cancer in 2020 and predictions to 2040
10.1016/j.jhep.2022.08.021 · ExternalCitation · doi-reference
Human exposure to Bisphenol A and liver health status: Quantification of urinary and circulating levels by LC-MS/MS
10.1016/j.jpba.2017.02.058 · ExternalCitation · doi-reference
The role of vasoactive intestinal peptide in pulmonary diseases
10.1016/j.lfs.2023.122121 · ExternalCitation · doi-reference
Tumor microenvironment and metabolic reprogramming in MASLD-related hepatocellular carcinoma
10.1016/j.molmed.2026.04.010 · ExternalCitation · doi-reference
Multiscale identification of DNASE1L3 as a key target in MASLD progression to hepatocellular carcinoma
10.1016/j.prp.2025.156192 · ExternalCitation · doi-reference
MASLD and MASLD-associated HCC: emerging biomarkers and therapeutic avenues
10.1016/j.scib.2026.04.048 · ExternalCitation · doi-reference
VIPR1 acts as an enteric neural checkpoint that suppresses intestinal stem cell-driven epithelial regeneration and exacerbates colitis
10.1016/j.stem.2026.01.009 · ExternalCitation · doi-reference
Systematic review of the potential carcinogenicity of bisphenol A in humans
10.1016/j.yrtph.2023.105414 · ExternalCitation · doi-reference
beta-Arrestin-independent endosomal cAMP signaling by a polypeptide hormone GPCR
10.1038/s41589-023-01412-4 · ExternalCitation · doi-reference
Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring
10.1038/s42255-024-01019-6 · ExternalCitation · doi-reference
Environmental pollutants, occupational exposures, and liver disease
10.1055/a-2540-2861 · ExternalCitation · doi-reference
The maximal affinity of ligands
10.1073/pnas.96.18.9997 · ExternalCitation · doi-reference
Stat3 is a candidate epigenetic biomarker of perinatal Bisphenol A exposure associated with murine hepatic tumors with implications for human health
10.1080/15592294.2015.1107694 · ExternalCitation · doi-reference
The role of Aurora kinase A in hepatocellular carcinoma: Unveiling the intriguing functions of a key but still underexplored factor in liver cancer
10.1111/cpr.13641 · ExternalCitation · doi-reference
VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins
10.1111/j.1476-5381.2011.01676.x · ExternalCitation · doi-reference
Deregulation of the Genes that Are Involved in Drug Absorption, Distribution, Metabolism, and Excretion in Hepatocellular Carcinoma
10.1124/jpet.118.255018 · ExternalCitation · doi-reference
Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization
10.1158/1535-7163.mct-11-0323 · ExternalCitation · doi-reference
Mechanistic exploration of bisphenol A in primary Sjogren's syndrome using network toxicology, molecular docking, molecular dynamics simulations and experimental validation
10.1186/s40360-025-01070-3 · ExternalCitation · doi-reference
Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A
10.1590/s1413-81232012000200015 · ExternalCitation · doi-reference
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development
10.20892/j.issn.2095-3941.2019.0335 · ExternalCitation · doi-reference
