Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol elicit MASLD-related lipid metabolic perturbations in HepG2 cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Cytotoxic and antimicrobial analysis of biosynthesized selenium nanoparticles from Solanum tuberosum peels
2025 · External reference
Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models
10.1016/j.envint.2024.108820 · 2024 · External reference
Organophosphate pesticides: Another silent liver hazard?
10.1111/liv.15492 · 2023 · External reference
TANK-binding kinase 1 protects against MASH progression via mitochondrial quality control
10.1038/s12276-026-01672-9 · 2026 · External reference
Effect of intoxication by gavage with pyrethroid and neonicotinoid insecticides on the liver in adult male rats of the Wistar strain
2022 · External reference
Studying the Antimicrobial Effects of Silver Nanoparticles (AgNPs) Derived from the Agricultural Byproduct of Rhus coriaria L. (Sumac)
2026 · External reference
The nexus of environmental endocrine-disrupting chemical exposure and metabolic dysfunction-associated steatotic liver disease: An emerging public health challenge
10.1016/j.ecoenv.2025.119513 · 2026 · External reference
Liver transplantation in patients with metabolic dysfunction and alcohol-related liver disease (MetALD)
2026 · External reference
Hepatotoxicity and nephrotoxicity induced by the chlorpyrifos and chlorpyrifos-methyl metabolite, 3,5,6-trichloro-2-pyridinol, in orally exposed mice
10.1016/j.scitotenv.2015.11.162 · 2016 · External reference
Acute toxicity of chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol alone and in combination using a battery of bioassays
10.1007/s11356-020-09392-x · 2020 · External reference
Single and joint toxicity of ethoprophos and bispyribac-sodium to Oreochromis niloticus: biochemical and genotoxic responses
10.1007/s10695-025-01490-2 · 2025 · External reference
The AMPK pathway in fatty liver disease
10.3389/fphys.2022.970292 · 2022 · External reference
Exposure to the environmental pollutant chlorpyrifos induces hepatic toxicity through activation of the JAK/STAT and MAPK pathways
2024 · External reference
MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion
2024 · External reference
Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector
10.1016/j.exger.2023.112134 · 2023 · External reference
Hepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis
10.1038/s41467-025-58790-7 · 2025 · External reference
LPI-GPR55 promotes endothelial cell activation and inhibits autophagy through inducing LINC01235 expression
10.1080/07853890.2024.2407525 · 2024 · External reference
Metabolic dysfunction-associated steatotic liver disease in adults
10.1038/s41572-025-00599-1 · 2025 · External reference
Pesticide metabolite 3, 5, 6-trichloro-2-pyridinol causes massive damage to the cochlea resulting in hearing loss in adult mice
10.1016/j.envpol.2024.124691 · 2024 · External reference
Evaluation of in Vivo Wound Healing Activity of Pistacia vera L. Hull Extract on Excision Wound Model in Rats
2026 · External reference
Lipotoxicity-driven metabolic dysfunction-associated steatotic liver disease (MASLD)
10.1016/j.atherosclerosis.2024.119053 · 2025 · External reference
Serial Cross-Sectional Human Biomonitoring Analysis of Pesticide Exposure Patterns and Their Association with Lipid Metabolism Biomarkers: The Mediating Role of Liver Function
10.1021/envhealth.5c00030 · 2025 · External reference
Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism
10.1016/j.cmet.2025.01.016 · 2025 · External reference
HSD17beta11 regulates PLIN5-ATGL mediated lipolysis, but not hepatic lipid metabolism in mice
10.1016/j.jlr.2025.100943 · 2025 · External reference
The Expectation and Reality of the HepG2 Core Metabolic Profile
10.3390/metabo13080908 · 2023 · External reference
Attenuation of high-fat diet-induced weight gain by apolipoprotein A4
10.1002/oby.24155 · 2024 · External reference
Membrane phospholipid remodeling modulates nonalcoholic steatohepatitis progression by regulating mitochondrial homeostasis
10.1097/hep.0000000000000375 · 2024 · External reference
Developmental neurotoxic effects of dibutyl phthalate and its metabolite mono-n-butyl phthalate on Danio rerio
10.1016/j.ecoenv.2025.119634 · 2026 · External reference
Liver muscle bone axis in metabolic dysfunction-associated steatotic liver disease
2026 · External reference
Association of Di(2-ethylhexyl) Terephthalate and Its Metabolites with Nonalcoholic Fatty Liver Disease: An Epidemiology and Toxicology Study
10.1021/acs.est.3c09503 · 2024 · External reference
Analysis of environmental chemical mixtures and nonalcoholic fatty liver disease: NHANES 1999-2014
10.1016/j.envpol.2022.119915 · 2022 · External reference
Impact of per- and polyfluoroalkyl substances structure on oxidative stress and lipid metabolism disruption in HepG2 cells
10.1016/j.tox.2025.154218 · 2025 · External reference
Damaging mutations in liver X receptor-alpha are hepatotoxic and implicate cholesterol sensing in liver health
10.1038/s42255-024-01126-4 · 2024 · External reference
DGAT1 and DGAT2 Inhibitors for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management: Benefits for Their Single or Combined Application
10.3390/ijms25169074 · 2024 · External reference
PLIN1 suppresses glioma progression through regulating lipid metabolism
10.1038/s41419-025-07347-z · 2025 · External reference
Association of urinary chlorpyrifos, paraquat, and cyproconazole levels with the severity of fatty liver based on MRI
10.1186/s12889-024-18129-1 · 2024 · External reference
Lipid-associated macrophages in metabolic dysfunction-associated steatotic liver disease: immune regulation of lipid burden
2026 · External reference
Protective effects of indole-3-propionic acid against TCP-induced hearing loss in mice by mitigating oxidative stress and promoting neutrophil recruitment
10.1038/s41598-025-90655-3 · 2025 · External reference
Pesticide and Liver Biomarkers Among Ecuadorian Adolescents and Adults Living in Agricultural Settings
10.3390/toxics13080685 · 2025 · External reference
Chlorpyrifos induces cytotoxicity via oxidative stress and mitochondrial dysfunction in HepG2 cells
10.1016/j.fct.2024.114933 · 2024 · External reference
Effects of environmentally relevant concentrations of glyphosate and aminomethylphosphonic acid on biotransformation and stress response proteins in the liver of zebrafish (Danio rerio)
2025 · External reference
The Multifaceted Role of Cytochrome P450 Isoenzymes in Alcoholic and Metabolic (Dysfunction) Fatty Liver Diseases
10.2174/0113892002422091251125072745 · 2026 · External reference
Different effects of polyethylene microplastics on bioaccumulation of three fungicides in maize (Zea mays L.)
10.1007/s44297-024-00028-x · 2024 · External reference
A multisociety Delphi consensus statement on new fatty liver disease nomenclature
10.1016/j.jhep.2023.06.003 · 2023 · External reference
A comprehensive review on environmental dynamics of chlorpyrifos: Fate, toxicity, remediation, and regulatory aspects
10.1016/j.ecoenv.2025.119484 · 2025 · External reference
Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge
10.1186/s13059-023-03075-9 · 2023 · External reference
Functional, eco-friendly, and starch-based nanocarriers with sustained release of carvacrol for persistent control of tomato gray mold
10.1007/s44297-023-00014-9 · 2023 · External reference
The human testis-enriched HSPA2 interacts with HIF-1alpha in epidermal keratinocytes, yet HIF-1alpha stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity
10.1016/j.bbamcr.2024.119735 · 2024 · External reference
Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model
10.1093/toxsci/kfae110 · 2024 · External reference
A Simple Physiologically Based Toxicokinetic Model for Multi-Route In Vitro–In Vivo Extrapolation
10.1021/acs.estlett.4c00967 · 2025 · External reference
Agrochemical exposure-induced seed microbiome response in barley
10.1007/s44297-023-00013-w · 2023 · External reference
Mogat1 drives metabolic adaptations to evade immune surveillance
10.1038/s41467-025-62134-w · 2025 · External reference
Dose-dependent effects of chlorpyrifos on liver injury, intestinal dysbiosis, and metabolic perturbations in C57BL/6J mice
10.1016/j.toxlet.2025.03.011 · 2025 · External reference
Effects of the organochlorine pesticide metabolite p,p′-DDE on the gastrointestinal lipidome in fish: A novel toxicity pathway for a legacy pollutant☆
10.1016/j.envpol.2024.125191 · 2024 · External reference
Benzopyrene Aggravates Nonalcoholic Liver Fatty Diseases in Female Mice Via the AHR/ERα Axis
10.2174/0115665240338923241219152329 · 2025 · External reference
Polychlorinated Biphenyl Quinone Promotes Atherosclerosis through Lipid Accumulation and Endoplasmic Reticulum Stress via CD36
10.1021/acs.chemrestox.0c00123 · 2020 · External reference
Targeted inhibition of hepatic de novo ceramide synthesis ameliorates MASH
10.1126/sciadv.adx2681 · 2025 · External reference
Imidacloprid Transformation Products Exhibit Stronger Developmental Neurotoxicity than the Parent Compound in Zebrafish (Danio rerio) via the Glutamate Signaling Pathway
10.1021/acs.est.6c00401 · 2026 · External reference
Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms
10.1016/j.ecoenv.2025.117747 · 2025 · External reference
Lipid metabolism in liver transplantation: from challenge to chance
2025 · External reference
Deciphering the impact of greenhouse pesticides on hepatic metabolism profile: Toxicity experiments on HepG2 cells using chlorpyrifos and emamectin benzoate
10.1016/j.ecoenv.2024.116230 · 2024 · External reference
Absolute quantitative lipidomics reveals lipids profiling in liver of mice with early-stage alcoholic liver disease
10.1186/s12986-022-00679-z · 2022 · External reference
α-Lipoic acid ameliorates arsenic-induced lipid disorders by promoting peroxisomal β-oxidation and reducing lipophagy in chicken hepatocyte
2025 · External reference