Research graph
References from SIRT6-COX6A1 axis mediates prenatal 6:2 FTOH-induced neuronal damage via mitochondrial dysfunction. Local targets link to admitted publications; unresolved targets remain external evidence.
Chlorinated polyfluoroalkyl ether sulfonic acids in matched maternal, cord, and placenta samples: a study of transplacental transfer
10.1021/acs.est.6b06049 · 2017 · External reference
Mitochondria at the neuronal presynapse in health and disease
10.1038/nrn.2017.170 · 2018 · External reference
Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies
10.1136/gut.2006.119180 · 2008 · External reference
SIRT6 through the brain evolution, development, and aging
10.3389/fnagi.2021.747989 · 2021 · External reference
Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
10.1016/s1474-4422(24)00038-3 · 2024 · External reference
Occurrence of PFAS in cow's milk: a comparative study of Swedish farms near contaminated sites and regional dairy production facilities
10.1021/acs.jafc.5c07211 · 2026 · External reference
Neurobehavioural effects of developmental toxicity
10.1016/s1474-4422(13)70278-3 · 2014 · External reference
Synaptic energy use and supply
10.1016/j.neuron.2012.08.019 · 2012 · External reference
Arsenic speciation transported through the placenta from mother mice to their newborn pups
10.1016/j.envres.2005.11.006 · 2006 · External reference
Internal exposure-based pharmacokinetic evaluation of potential for biopersistence of 6:2 fluorotelomer alcohol (FTOH) and its metabolites
10.1016/j.fct.2018.01.012 · 2018 · External reference
Neuroprotective functions for the histone deacetylase SIRT6
10.1016/j.celrep.2017.03.008 · 2017 · External reference
Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis
10.1101/gad.13.11.1475 · 1999 · External reference
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
10.1038/nature05292 · 2006 · External reference
Deoxynivalenol and Aflatoxin B(1) coexposure aggravated intestinal damage via ER stress-meditated mitochondrial dyshomeostasis and apoptosis
10.1021/acs.jafc.5c08063 · 2025 · External reference
CB-Dock2: improved protein-ligand blind docking by integrating cavity detection, docking and homologous template fitting
10.1093/nar/gkac394 · 2022 · External reference
Combined stress from thiamethoxam and pyrethroids exacerbates metabolic dysregulation and quality deterioration in Pak Choi (Brassica chinensis L)
10.1021/acs.jafc.5c10177 · 2026 · External reference
Mitochondria: in sickness and in health
10.1016/j.cell.2012.02.035 · 2012 · External reference
Evaluation of the reproductive and developmental toxicity of 6:2 fluorotelomer alcohol in rats
10.1016/j.tox.2014.01.002 · 2014 · External reference
Activity-driven local ATP synthesis is required for synaptic function
10.1016/j.cell.2013.12.042 · 2014 · External reference
Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
10.1016/j.fct.2023.114333 · 2024 · External reference
Inhalation and oral toxicokinetics of 6:2 FTOH and its metabolites in mammals
10.1016/j.chemosphere.2014.07.092 · 2015 · External reference
DART isotope dilution high resolution mass spectrometry and (19)F NMR detection of fluorotelomeric alcohols in hydrolyzed food contact paper
10.1080/19440049.2024.2423868 · 2025 · External reference
Toxicological evaluation of 6:2 fluorotelomer alcohol
10.1016/j.tox.2014.01.009 · 2014 · External reference
SIRT6 is a key regulator of mitochondrial function in the brain
10.1038/s41419-022-05542-w · 2023 · External reference
A mutation of COX6A1 causes a recessive axonal or mixed form of Charcot-Marie-Tooth disease
10.1016/j.ajhg.2014.07.013 · 2014 · External reference
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
10.1073/pnas.250422697 · 2000 · External reference
The role of mitochondria in apoptosis*
10.1146/annurev-genet-102108-134850 · 2009 · External reference
Embryonic 6:2 fluorotelomer alcohol exposure disrupts the blood-brain barrier by causing endothelial-to-mesenchymal transition in the male mice
10.1007/s12035-024-04540-7 · 2025 · External reference
Gestational exposure to a fluorotelomer alcohol causes behavioral abnormalities by disrupting the blood-brain barrier in offspring
10.1007/s10311-024-01707-5 · 2024 · External reference
Embryonic exposure to 6:2 fluorotelomer alcohol mediates autism spectrum disorder-like behavior by dysfunctional microbe-gut-brain axis in mice
10.1016/j.jhazmat.2024.136739 · 2025 · External reference
In utero exposure to DBP stimulates release of GnRH by increasing the secretion of PGE2 in the astrocytes of the hypothalamus in the offspring mice
10.1016/j.ecoenv.2020.110698 · 2020 · External reference
Emerging poly- and perfluoroalkyl substances in the aquatic environment: a review of current literature
10.1016/j.watres.2017.07.024 · 2017 · External reference
Pyrethroid insecticide cypermethrin accelerates pubertal onset in male mice via disrupting hypothalamic-pituitary-gonadal axis
10.1021/acs.est.7b02739 · 2017 · External reference
Ubiquitous occurrence of fluorotelomer alcohols in eco-friendly paper-made food-contact materials and their implication for human exposure
10.1021/acs.est.5b03806 · 2016 · External reference
