Research graph
References from NOX4-related ROS couples PET micro- and nanoplastic exposure to JAK2/STAT3 activation in clear cell renal cell carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
The emerging role of microplastics in systemic toxicity: involvement of reactive oxygen species (ROS)
10.1016/j.scitotenv.2023.165076 · 2023 · External reference
Quality criteria for microplastic effect studies in the context of risk assessment: A critical review
10.1021/acs.est.0c03057 · 2020 · External reference
KIF2C promotes clear cell renal cell carcinoma progression via activating JAK2/STAT3 signaling pathway
10.1016/j.mcp.2023.101938 · 2023 · External reference
Production, use, and fate of all plastics ever made
10.1126/sciadv.1700782 · 2017 · External reference
Addressing the relevance of polystyrene nano- and microplastic particles used to support exposure, toxicity and risk assessment: Implications and recommendations
10.1186/s12989-024-00599-1 · 2024 · External reference
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis
10.1016/j.tox.2024.153996 · 2024 · External reference
Detection of microplastics in human lung tissue using μFTIR spectroscopy
10.1016/j.scitotenv.2022.154907 · 2022 · External reference
Microplastics and oxidative stress-current problems and prospects
10.3390/antiox13050579 · 2024 · External reference
Microplastic diagnostics in humans: “the 3Ps” progress, problems, and prospects
10.1016/j.scitotenv.2022.159164 · 2023 · External reference
Microplastic exposure studies should be environmentally realistic
10.1073/pnas.1606615113 · 2016 · External reference
Discovery and quantification of plastic particle pollution in human blood
10.1016/j.envint.2022.107199 · 2022 · External reference
IL1R2 promotes tumor progression via JAK2/STAT3 pathway in human clear cell renal cell carcinoma
10.1016/j.prp.2022.154069 · 2022 · External reference
MicroRaman spectroscopy detects the presence of microplastics in human urine and kidney tissue
10.1016/j.envint.2024.108444 · 2024 · External reference
Effects of nano- and microplastics on kidney: Physicochemical properties, bioaccumulation, oxidative stress and immunoreaction
10.1016/j.chemosphere.2021.132631 · 2022 · External reference
Environmental exposure to microplastics: An overview on possible human health effects
10.1016/j.scitotenv.2019.134455 · 2020 · External reference
Plasticenta: First evidence of microplastics in human placenta
10.1016/j.envint.2020.106274 · 2021 · External reference
Potential benefits and harms of NADPH oxidase type 4 in the kidneys and cardiovascular system
10.1093/ndt/gfy161 · 2019 · External reference
Detection of microplastics in human tissues and organs: A scoping review
10.7189/jogh.14.04179 · 2024 · External reference
Microplastics as both a driver of genitourinary cancers and a deliverer of treatments
10.1038/s43856-026-01675-7 · 2026 · External reference
Microplastics and nanoplastics: Size, surface and dispersant - what causes the effect?
10.1016/j.tiv.2022.105314 · 2022 · External reference
Uptake and cellular effects of PE, PP, PET and PVC microplastic particles
10.1016/j.tiv.2020.105021 · 2021 · External reference
Lost at sea: Where is all the plastic?
10.1126/science.1094559 · 2004 · External reference
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress
10.1038/s41374-019-0203-3 · 2019 · External reference
The kidney-related effects of polystyrene microplastics on human kidney proximal tubular epithelial cells HK-2 and male C57BL/6 mice
10.1289/ehp7612 · 2021 · External reference
PBX1 promotes the cell proliferation via JAK2/STAT3 signaling in clear cell renal carcinoma
10.1016/j.bbrc.2018.04.127 · 2018 · External reference
Micro- and nanoplastics concepts for particle and fibre toxicologists
10.1186/s12989-024-00581-x · 2024 · External reference
Single-cell RNA-seq analysis decodes the kidney microenvironment induced by polystyrene microplastics in mice receiving a high-fat diet
10.1186/s12951-023-02266-7 · 2024 · External reference
Polystyrene microplastics exposure aggravates clear cell renal cell carcinoma progression via the NF-κB and TGF-β signaling pathways
10.1002/advs.202518500 · 2026 · External reference
Revisiting STAT3 signalling in cancer: New and unexpected biological functions
10.1038/nrc3818 · 2014 · External reference
Exposure to polystyrene microplastic differentially affects the colon and liver in adult male mice
10.1002/tox.24486 · 2025 · External reference
Multimodal detection and analysis of microplastics in human clear cell renal cell carcinoma
10.1016/j.envpol.2025.126729 · 2025 · External reference
Detection and quantification of microplastics in various types of human tumor tissues
10.1016/j.ecoenv.2024.116818 · 2024 · External reference
