Research graph
References from Impact of serum PFAS levels on chronic obstructive pulmonary disease: A comprehensive analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
NCBI GEO: archive for functional genomics data sets--update
10.1093/nar/gks1193 · 2013 · External reference
Absorption, distribution, and toxicity of per- and polyfluoroalkyl substances (PFAS) in the brain: a review
10.1039/d1em00228g · 2021 · External reference
Association between chronic obstructive pulmonary disease and cardiovascular disease in adults aged 40 years and above: data from NHANES 2013-2018
10.1186/s12890-023-02606-1 · 2023 · External reference
DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease
10.1038/s41392-024-01881-6 · 2024 · External reference
Impact of polyfluoroalkyl chemicals and volatile organic compounds exposure on lung function of American adults
10.1016/j.envpol.2024.125152 · 2024 · External reference
Assessment of weighted quantile sum regression for modeling chemical mixtures and cancer risk
2015 · External reference
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
10.1093/nar/gkz382 · 2019 · External reference
Perfluoroalkyl Substances (PFAS) Affect Inflammation in Lung Cells and Tissues
10.3390/ijms24108539 · 2023 · External reference
Plasma levels of per- and polyfluoroalkyl substances (PFAS) and cardiovascular disease - Results from two independent population-based cohorts and a meta-analysis
10.1016/j.envint.2023.108250 · 2023 · External reference
AutoDock Vina 1.2.0: new docking methods, expanded force field, and python bindings
10.1021/acs.jcim.1c00203 · 2021 · External reference
Gene expression networks in COPD: microRNA and mRNA regulation
10.1136/thoraxjnl-2011-200089 · 2012 · External reference
Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
10.26508/lsa.202201535 · 2023 · External reference
Role for cathepsin K in emphysema in smoke-exposed guinea pigs
10.3109/01902140902822304 · 2009 · External reference
Goto S. KEGG: kyoto encyclopedia of genes and genomes
10.1093/nar/28.1.27 · 2000 · External reference
PubChem in 2021: new data content and improved web interfaces
10.1093/nar/gkaa971 · 2021 · External reference
Associations of PFAS and pesticides with lung function changes from adolescence to young adulthood in the ESPINA study
10.1016/j.ijheh.2025.114526 · 2025 · External reference
The sva package for removing batch effects and other unwanted variation in high-throughput experiments
2012 · External reference
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema
10.2147/copd.s354896 · 2022 · External reference
Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways
10.1016/j.ecoenv.2023.114980 · 2023 · External reference
CB-Dock2: improved protein-ligand blind docking by integrating cavity detection, docking and homologous template fitting
10.1093/nar/gkac394 · 2022 · External reference
Exposure to perfluorodecanoic acid impairs follicular development via inducing granulosa cell necroptosis
10.1016/j.ecoenv.2024.117268 · 2024 · External reference
Increased perfluorooctanoic acid accumulation facilitates the migration and invasion of lung cancer cells via remodeling cell mechanics
10.1073/pnas.2408575121 · 2024 · External reference
The Association of Toll-like Receptor-9 Gene Single-Nucleotide Polymorphism and AK155(IL-26) Serum Levels with Chronic Obstructive Pulmonary Disease Exacerbation Risk: A Case-Controlled Study with Bioinformatics Analysis
10.3390/biomedicines13030613 · 2025 · External reference
Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue
10.1038/srep44232 · 2017 · External reference
Dihydroartemisinin, a potential PTGS1 inhibitor, potentiated cisplatin-induced cell death in non-small cell lung cancer through activating ROS-mediated multiple signaling pathways
10.1016/j.neo.2024.100991 · 2024 · External reference
Moderate-intensity physical activity reduces the role of serum PFAS on COPD: A cross-sectional analysis with NHANES data
10.1371/journal.pone.0308148 · 2024 · External reference
Polycyclic aromatic hydrocarbon exposure burden: Individual and mixture analyses of associations with chronic obstructive pulmonary disease risk
10.1016/j.envres.2023.115334 · 2023 · External reference
Asthma and decreased lung function in children exposed to perfluoroalkyl and polyfluoroalkyl substances (PFAS): An updated meta-analysis unveiling research gaps
10.1016/j.envres.2024.119827 · 2024 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
Perfluoroalkyl/Polyfluoroalkyl Substances: Links to Cardiovascular Disease Risk
10.1161/circresaha.124.323697 · 2024 · External reference
Cytoscape: a software environment for integrated models of biomolecular interaction networks
10.1101/gr.1239303 · 2003 · External reference
Developing an interpretable machine learning predictive model of chronic obstructive pulmonary disease by serum PFAS concentration
10.3389/fpubh.2025.1602566 · 2025 · External reference
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
10.1093/nar/gkab1061 · 2022 · External reference
GOLD COPD report: 2025 update
10.1016/s2213-2600(24)00413-2 · 2025 · External reference
Gut microbiome and transcriptomic changes in cigarette smoke-exposed mice compared to COPD and CD patient datasets
2024 · External reference
Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
10.1038/s41467-021-23201-0 · 2021 · External reference
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)
10.1007/s00204-023-03477-5 · 2023 · External reference
Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment
10.1016/s2213-2600(21)00506-3 · 2022 · External reference
TargetNet: a web service for predicting potential drug-target interaction profiling via multi-target SAR models
10.1007/s10822-016-9915-2 · 2016 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
Unveiling the role of cathepsins on lung function in chronic obstructive pulmonary disease: a Mendelian randomization analysis
10.2147/copd.s507283 · 2025 · External reference
Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways
10.1016/j.molimm.2023.10.007 · 2023 · External reference
Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
10.1186/s12931-023-02598-w · 2023 · External reference
National health and nutrition examination survey: plan and operations, 1999-2010
2013 · External reference