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References from Co-exposure to polystyrene nanoplastics and di(2-ethylhexyl) phthalate: Effects and mechanistic insights into hepatic lipid metabolism in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
The Endoplasmic Reticulum and the Cellular Reticular Network
2017 · External reference
Di-2-Ethylhexyl Phthalate (DEHP) Toxicity: Organ-Specific Impacts and Human-Relevant Findings in Animal Models & Humans - Review
2025 · External reference
Global concentrations of microplastics in soils – a review
10.5194/soil-6-649-2020 · 2020 · External reference
Combustion and friction-derived nanoparticles and industrial-sourced nanoparticles: The culprit of Alzheimer and Parkinson’s diseases
10.1016/j.envres.2019.108574 · 2019 · External reference
Mapping the hidden journey of microplastics: Multi-organ deposition patterns and organ-specific health risks revealed by AI-driven analysis
2025 · External reference
LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models
10.1161/circresaha.119.316424 · 2020 · External reference
Polystyrene nanoplastics-induced altered glycolipid metabolism in the liver: A comparative study between pregnant and non-pregnant mice
10.1016/j.ecoenv.2025.119440 · 2025 · External reference
Polystyrene microplastics induce hepatotoxicity and disrupt lipid metabolism in the liver organoids
10.1016/j.scitotenv.2021.150328 · 2022 · External reference
Subchronic oral exposure to polystyrene microplastics affects hepatic lipid metabolism, inflammation, and oxidative balance in gilthead seabream (Sparus aurata)
10.1016/j.ecoenv.2024.116455 · 2024 · External reference
Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut
10.1016/j.envint.2020.105916 · 2020 · External reference
Synthetic fibers in atmospheric fallout: A source of microplastics in the environment?
10.1016/j.marpolbul.2016.01.006 · 2016 · External reference
Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota
10.1007/s12602-024-10439-5 · 2025 · External reference
Impact of DEHP on mitochondria-associated endoplasmic reticulum membranes and reproductive toxicity in ovary
10.1016/j.ecoenv.2024.116679 · 2024 · External reference
An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling
10.1016/j.jhazmat.2017.10.014 · 2018 · External reference
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
10.1186/s12989-020-00387-7 · 2020 · External reference
Microplastics detected in cirrhotic liver tissue
10.1016/j.ebiom.2022.104147 · 2022 · External reference
Chronic exposure to environmentally relevant levels of di(2-ethylhexyl) phthalate (DEHP) disrupts lipid metabolism associated with SBP-1/SREBP and ER stress in C. elegans
10.1016/j.envpol.2022.119579 · 2022 · External reference
In-depth profiling of di(2-ethylhexyl) phthalate metabolic footprints in rats using click chemistry-mass spectrometry probes
10.1016/j.jhazmat.2023.131190 · 2023 · External reference
Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver via activating the LXR/SREBP-1c/PPARα/γ and NF-κB signaling pathway
10.1016/j.fct.2022.113119 · 2022 · External reference
Plastic nanoparticles cause proteome stress and aggregation by compromising cellular protein homeostasis ex vivo and in vivo
10.1016/j.ecoenv.2023.115347 · 2023 · External reference
Non-invasive assessment of liver steatosis in non-alcoholic fatty liver disease
10.1111/hepr.12330 · 2014 · External reference
A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens
10.3389/fendo.2021.724989 · 2021 · External reference
Characterisation of nanoplastics during the degradation of polystyrene
10.1016/j.chemosphere.2015.11.078 · 2016 · External reference
Exposure scenarios for human health risk assessment of nano- and microplastic particles
10.1186/s43591-025-00134-9 · 2025 · External reference
Long-Term Exposure to Low-Dose Di-(2-ethylhexyl) Phthalate Impairs Cholesterol Metabolism in Hepatic Stellate Cells and Exacerbates Liver Fibrosis
10.3390/ijerph17113802 · 2020 · External reference
Short-term exposure to di(2-ethylhexyl)phthalate may disrupt hepatic lipid metabolism through modulating the oxidative stress in male adolescent rats
10.5620/eaht.2024007 · 2024 · External reference
Di(2-ethylhexyl) phthalate disturbs cholesterol metabolism through oxidative stress in rat liver
10.1016/j.etap.2022.103958 · 2022 · External reference
Exposure to submicroplastics promotes the progression of nonalcoholic fatty liver disease in ApoE-deficient mice
10.1016/j.tox.2025.154137 · 2025 · External reference
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation
2025 · External reference
Di-2-ethylhexyl phthalate disrupts hepatic lipid metabolism in obese mice by activating the LXR/SREBP-1c and PPAR-α signaling pathways
10.1016/j.scitotenv.2024.169919 · 2024 · External reference
Impacts of polypropylene microplastics on lipid profiles of mouse liver uncovered by lipidomics analysis and Raman spectroscopy
10.1016/j.jhazmat.2023.131918 · 2023 · External reference
Effects of aging on environmental behavior of plastic additives: Migration, leaching, and ecotoxicity
10.1016/j.scitotenv.2022.157951 · 2022 · External reference
Untargeted lipidomics uncover hepatic lipid signatures induced by long-term exposure to polystyrene microplastics in vivo
10.1016/j.toxlet.2024.07.914 · 2024 · External reference
Microplastics in the Environment: Intake through the Food Web, Human Exposure and Toxicological Effects
10.3390/toxics9090224 · 2021 · External reference
Microplastics research—from sink to source
10.1126/science.aar7734 · 2018 · External reference
Combined exposure to di(2-ethylhexyl) phthalate and polystyrene microplastics induced renal autophagy through the ROS/AMPK/ULK1 pathway
10.1016/j.fct.2022.113521 · 2023 · External reference
Lost at Sea: Where Is All the Plastic?
10.1126/science.1094559 · 2004 · External reference
Beyond Mechanical Recycling: Giving New Life to Plastic Waste
10.1002/anie.201915651 · 2020 · External reference
Toxic effects of DEHP and MEHP on gut-liver axis in rats via intestinal flora and metabolomics
10.1016/j.isci.2024.111135 · 2024 · External reference
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis
10.1016/j.cmet.2012.09.003 · 2012 · External reference
Phthalates and Their Impacts on Human Health
10.3390/healthcare9050603 · 2021 · External reference
Microplastics and di (2-ethylhexyl) phthalate synergistically induce apoptosis in mouse pancreas through the GRP78/CHOP/Bcl-2 pathway activated by oxidative stress
10.1016/j.fct.2022.113315 · 2022 · External reference
Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation
10.1038/ncb3551 · 2017 · External reference
Nano polystyrene microplastics could accumulate in Nile tilapia (Oreochromis niloticus): Negatively impacts on the intestinal and liver health through water exposure
10.1016/j.jes.2023.02.018 · 2024 · External reference
Polystyrene-microplastics and DEHP co-exposure induced DNA damage, cell cycle arrest and necroptosis of ovarian granulosa cells in mice by promoting ROS production
10.1016/j.scitotenv.2023.161962 · 2023 · External reference
Di(2-ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study
10.1002/tox.23648 · 2022 · External reference
Concurrent increase in fatty acid oxidation and fatty acid synthesis: a unique metabolic state in a pig model of pediatric steatotic liver disease
10.1152/ajpendo.00299.2025 · 2026 · External reference
Microplastics and nanoplastics: Emerging drivers of hepatic pathogenesis and metabolic dysfunction
10.14744/hf.2025.58577 · 2025 · External reference
Transcriptome Sequencing and Metabolite Analysis Revealed the Single and Combined Effects of Microplastics and Di-(2-ethylhexyl) Phthalate on Mouse Liver
10.3390/ijms26104943 · 2025 · External reference
Microplastics and nanoplastics in drinking water and beverages: occurrence and human exposure
10.20517/jeea.2024.37 · 2024 · External reference
Identification of Poly(ethylene terephthalate) Nanoplastics in Commercially Bottled Drinking Water Using Surface-Enhanced Raman Spectroscopy
10.1021/acs.est.3c00842 · 2023 · External reference
Network toxicology and machine learning revealed the association between non-alcoholic fatty liver disease induced by polystyrene nanoplastics
10.1016/j.ecoenv.2026.120058 · 2026 · External reference
Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity
10.1039/d1fo00478f · 2021 · External reference
The effect of di-2-ethylhexyl phthalate on inflammation and lipid metabolic disorder in rats
10.1016/j.ecoenv.2018.12.009 · 2019 · External reference
PPARγ mediated lysosomal membrane permeabilization and lipophagy blockage were involved in microplastics and di (2-ethylhexyl) phthalate co-exposure induced immature testis injury
10.1016/j.freeradbiomed.2025.06.023 · 2025 · External reference
