Research graph
References from Non-muscle actinopathy-associated loss-of-function actin variants modulate cytoskeletal reorganization. Local targets link to admitted publications; unresolved targets remain external evidence.
A time- and cost-efficient system for high-level protein production in mammalian cells
10.1107/s0907444906029799 · 2006 · External reference
Structural insights into actin isoforms
10.7554/elife.82015 · 2023 · External reference
Focal adhesions are controlled by microtubules through local contractility regulation
10.1038/s44318-024-00114-4 · 2024 · External reference
Further delineation of putative ACTB loss-of-function variants: A 4-patient series
10.1002/humu.23970 · 2020 · External reference
Extreme phenotypic variability of ACTG1-related disorders in hearing loss
2024 · External reference
Non-muscle myosin 2A (NM2A): structure, regulation and function
10.3390/cells9071590 · 2020 · External reference
Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro models
10.1242/dev.163766 · 2019 · External reference
ACTB loss-of-function mutations result in a pleiotropic developmental disorder
10.1016/j.ajhg.2017.11.006 · 2017 · External reference
[Overview of cytoskeletal actin mutations associated with rare diseases]
10.1556/650.2026.33533 · 2026 · External reference
Quantifying cytoskeletal organization from optical microscopy data
2023 · External reference
Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies
10.1016/j.ajhg.2025.12.007 · 2026 · External reference
Polarization of myosin ii refines tissue material properties to buffer mechanical stress
10.1016/j.devcel.2018.12.020 · 2019 · External reference
Stabilization of the actomyosin complex by negative charges on myosin
10.1021/bi000985x · 2000 · External reference
Quantitative and unbiased analysis of directional persistence in cell migration
10.1038/nprot.2014.131 · 2014 · External reference
The baraitser-winter cerebrofrontofacial syndrome recurrent r196h variant in cytoplasmic beta-actin impairs its cellular polymerization and stability
10.1096/fj.202502196r · 2026 · External reference
Molecular mechanisms of hotspot variants in cytoskeletal beta-actin associated with Baraitser-Winter syndrome
10.1111/febs.70018 · 2025 · External reference
The non-muscle actinopathy-associated mutation E334Q in cytoskeletal gamma-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins
10.7554/elife.93013 · 2024 · External reference
Multiscale characterization of Caenorhabditis elegans mutants to probe functional mechanisms of human actin pathological variants
10.1016/j.isci.2025.113652 · 2025 · External reference
BRAF modulates stretch-induced intercellular gap formation through localized actin reorganization
10.3390/ijms22168989 · 2021 · External reference
Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments
10.1073/pnas.1915987117 · 2020 · External reference
Calibration of atomic-force microscope tips
10.1063/1.1143970 · 1993 · External reference
Conventional and non-conventional roles of non-muscle myosin ii-actin in neuronal development and degeneration
10.3390/cells9091926 · 2020 · External reference
Spatially and temporally synchronized atomic force and total internal reflection fluorescence microscopy for imaging and manipulating cells and biomolecules
10.1529/biophysj.106.085456 · 2006 · External reference
Atomic force microscopy for university students: applications in biomaterials
10.1088/1361-6404/aa5cd6 · 2017 · External reference
Characterization of microtubule destabilizing drugs: a quantitative cell-based assay that bridges the gap between tubulin based- and cytotoxicity assays
10.3390/cancers13205226 · 2021 · External reference
The role of the microtubule cytoskeleton in neurodevelopmental disorders
10.3389/fncel.2018.00165 · 2018 · External reference
Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
10.1038/s41467-018-06713-0 · 2018 · External reference
New insights into FAK structure and function in focal adhesions
10.1242/jcs.259089 · 2022 · External reference
Methods for cell and particle tracking
10.1016/b978-0-12-391857-4.00009-4 · 2012 · External reference
Forces to drive neuronal migration steps
10.3389/fcell.2020.00863 · 2020 · External reference
Novel ACTG1 mutations in patients identified by massively parallel DNA sequencing cause progressive hearing loss
10.1038/s41598-020-63690-5 · 2020 · External reference
Non-muscle myosin II in disease: mechanisms and therapeutic opportunities
2015 · External reference
Crosstalk between myosin II and formin functions in the regulation of force generation and actomyosin dynamics in stress fibers
10.1016/j.cdev.2021.203736 · 2021 · External reference
Structural insights into actin filament turnover
10.1016/j.tcb.2024.12.009 · 2025 · External reference
Molecular mechanism of actin filament elongation by formins
10.1126/science.adn9560 · 2024 · External reference
Sculpting the dendritic landscape: actin, microtubules, and the art of arborization
10.1016/j.ceb.2023.102214 · 2023 · External reference
Essential nucleotide- and protein-dependent functions of Actb/beta-actin
10.1073/pnas.1807895115 · 2018 · External reference
A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia
10.1086/504271 · 2006 · External reference
Intellectual disability: dendritic anomalies and emerging genetic perspectives
10.1007/s00401-020-02244-5 · 2021 · External reference
Probing mechanical properties of living cells by atomic force microscopy with blunted pyramidal cantilever tips
10.1103/physreve.72.021914 · 2005 · External reference
Characterization of a beta-actin mRNA zipcode-binding protein
10.1128/mcb.17.4.2158 · 1997 · External reference
Actin: from structural plasticity to functional diversity
10.1016/j.ejcb.2011.05.002 · 2011 · External reference
Myosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration
10.1016/j.neuron.2009.05.028 · 2009 · External reference
Structural basis for cofilin binding and actin filament disassembly
10.1038/s41467-018-04290-w · 2018 · External reference
Regulation of cell adhesion and migration via microtubule cytoskeleton organization, cell polarity, and phosphoinositide signaling
10.3390/biom13101430 · 2023 · External reference
Multiple mechanisms to regulate actin functions: "fundamental" versus lineage-specific mechanisms and hierarchical relationships
10.3390/biom15020279 · 2025 · External reference
The amino acid sequence of Physarum actin
10.1038/276720a0 · 1978 · External reference
Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence
10.7554/elife.31661 · 2017 · External reference
10.1101/2023.03.27.534392
10.1101/2023.03.27.534392 · External reference
Baraitser-Winter cerebrofrontofacial syndrome: delineation of the spectrum in 42 cases
10.1038/ejhg.2014.95 · 2015 · External reference
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
10.1038/nature18295 · 2016 · External reference
