Research graph
References from Cyclometalated iridium complex with red-light activation for dual ferroptosis-apoptosis cancer therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Exploring treatment options in cancer: tumor treatment strategies
10.1038/s41392-024-01856-7 · 2024 · External reference
Neoantigens: promising targets for cancer therapy
10.1038/s41392-022-01270-x · 2023 · External reference
Understanding the novel approach of nanoferroptosis for cancer therapy
10.1007/s40820-024-01399-0 · 2024 · External reference
Targeting apoptotic pathways for cancer therapy
10.1172/jci179570 · 2024 · External reference
Cellular stress response and apoptosis in cancer therapy
10.1182/blood.v98.9.2603 · 2001 · External reference
Dual-locked targeted alpha-emitter enhanced tumor immunotherapy via Diels-Alder reaction-based self-immolative molecular cage strategy
10.1186/s40779-025-00673-5 · 2025 · External reference
Stressed to death: mitochondrial stress responses connect respiration and apoptosis in cancer
10.1016/j.molcel.2022.07.012 · 2022 · External reference
Recommendations for robust and reproducible research on ferroptosis
10.1038/s41580-025-00843-2 · 2025 · External reference
Pyroptosis-inducing Platinum(IV) prodrugs via GSDME pathway for chemoimmunotherapy and metastasis inhibition in triple-negative breast cancer
2025 · External reference
The therapeutic potential of targeting regulated non-apoptotic cell death
10.1038/s41573-023-00749-8 · 2023 · External reference
The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions
10.1016/j.ccell.2024.03.011 · 2024 · External reference
Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
10.1186/s13045-022-01392-3 · 2022 · External reference
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
10.1038/s41568-024-00674-x · 2024 · External reference
Endothelial heterogeneity in the response to autophagy drives small vessel muscularization in pulmonary hypertension
10.1161/circulationaha.124.068726 · 2024 · External reference
Sublethal cytochrome c release generates drug-tolerant persister cells
10.1016/j.cell.2022.07.025 · 2022 · External reference
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
10.1038/s41392-023-01720-0 · 2023 · External reference
Recent progress in ferroptosis inducers for cancer therapy
10.1002/adma.201904197 · 2019 · External reference
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest
10.1016/j.ccell.2025.09.010 · 2026 · External reference
Halofuginone disrupted collagen deposition via mTOR-eIF2α-ATF4 axis to enhance chemosensitivity in ovarian cancer
2025 · External reference
Engineering asymmetric and highly exposed Fe single-atom nanozymes for siMMP13 delivery and ferroptosis inhibition in osteoarthritis therapy
10.1002/adma.202520951 · 2026 · External reference
Biomimetic nanomotors for deep ischemia penetration and ferroptosis inhibition in neuroprotective therapy of ischemic stroke
2025 · External reference
A dual stimuli-responsive nanoplatform loaded Pt(IV) -Triptolide prodrug for achieving synergistic therapy toward breast cancer
10.1002/adhm.202301328 · 2023 · External reference
A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy
10.1016/j.biomaterials.2024.122574 · 2024 · External reference
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
10.1038/s41392-024-01769-5 · 2024 · External reference
PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8(+) T cell ferroptosis
10.1016/j.immuni.2024.08.003 · 2024 · External reference
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer
10.1038/s41392-024-01772-w · 2024 · External reference
Ultrathin clay nanoparticles-mediated mutual reinforcement of ferroptosis and cancer immunotherapy
2024 · External reference
Sickle cell disease induces chromatin introversion and ferroptosis in CD8(+) T cells to suppress anti-tumor immunity
10.1016/j.immuni.2025.04.020 · 2025 · External reference
DHODH modulates immune evasion of cancer cells via CDP-choline dependent regulation of phospholipid metabolism and ferroptosis
10.1038/s41467-025-59307-y · 2025 · External reference
Ferroptosis of T cell in inflammation and tumour immunity
10.1002/ctm2.70253 · 2025 · External reference
A new oxaliplatin(IV) prodrug inducing ferroptosis through a triple-pathway mechanism and activating anti-cancer immunity
10.1007/s11426-024-2683-9 · 2025 · External reference
Broadening Horizons: the role of ferroptosis in cancer
10.1038/s41571-020-00462-0 · 2021 · External reference
Ferroptotic therapy in cancer: benefits, side effects, and risks
10.1186/s12943-024-01999-9 · 2024 · External reference
Ferroptosis of tumour neutrophils causes immune suppression in cancer
10.1038/s41586-022-05443-0 · 2022 · External reference
Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: perspectives for immunotherapy of SCLC
10.1016/j.semcancer.2022.03.009 · 2022 · External reference
VDR activation attenuates renal tubular epithelial cell ferroptosis by regulating Nrf2/HO-1 signaling pathway in diabetic nephropathy
10.4028/b-wjqrp6 · 2024 · External reference
Cell death in pancreatic cancer: from pathogenesis to therapy
10.1038/s41575-021-00486-6 · 2021 · External reference
Human hematopoietic stem cell vulnerability to ferroptosis
10.1016/j.cell.2023.01.020 · 2023 · External reference
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria
10.1038/s41419-024-07237-w · 2024 · External reference
A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis
10.1038/s41556-025-01722-w · 2025 · External reference
Mitochondrion-targeted type I photodynamic therapy for agonist independent cGAS-STING activation
2025 · External reference
Cationization to boost both type I and type II ROS generation for photodynamic therapy
10.1016/j.biomaterials.2021.121255 · 2022 · External reference
Tailoring photosensitive ROS for advanced photodynamic therapy
10.1038/s12276-021-00599-7 · 2021 · External reference
Synergistic copper-Coordination/Glutathione reduction drives an in situ type II-to-Type I photodynamic switch in iridium-based photosensitizer nanocomposites for potentiated cancer immunotherapy
2025 · External reference
De Novo Design of Efficient NIR-II-Activated Heavy-Atom-Free Type-I Photosensitizer for Anti-Tumor Photoimmunotherapy
2025 · External reference
Rational design of Type-I photodynamic agents
10.1002/anie.202509416 · 2025 · External reference
A self-assembly-induced exciton delocalization strategy for converting a perylene diimide derivative from a Type-II to Type-I photosensitizer
2024 · External reference
Iridium(III) complexes as type I photosensitizers for hypoxic two-photon photodynamic therapy
10.1016/j.jinorgbio.2025.113006 · 2025 · External reference
Efficient enhancement of the visible-light absorption of cyclometalated Ir(III) complexes triplet photosensitizers with Bodipy and applications in photooxidation and triplet-triplet annihilation upconversion
10.1021/ic302210b · 2013 · External reference
In-Cell NAD(P)H photocatalysis with a metal complex for photocatalytic anticancer therapy
10.1021/acs.accounts.5c00455 · 2025 · External reference
Shedding light on photo-redox catalysis of a NIR iridium(III) complex for high photocytotoxicity against cisplatin resistant ovarian cancer in 3D tumor spheroids
10.1039/d5tb02239h · 2026 · External reference
Wavelength engineerable porous organic polymer photosensitizers with protonation triggered ROS generation
10.1038/s41467-023-37156-x · 2023 · External reference
Deep near infrared light-excited stable synergistic photodynamic and photothermal therapies based on P-IR890 nano-photosensitizer constructed via a non-cyanine dye
2024 · External reference
The course of immune stimulation by photodynamic therapy: bridging fundamentals of photochemically induced immunogenic cell death to the enrichment of T-Cell repertoire
10.1111/php.13173 · 2019 · External reference
Photodynamic priming with triple-receptor targeted nanoconjugates that trigger T cell-mediated immune responses in a 3D in vitro heterocellular model of pancreatic cancer
10.1515/nanoph-2021-0304 · 2021 · External reference
Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes
10.1016/j.jinorgbio.2019.110976 · 2020 · External reference
Multispecific Platinum(IV) complex deters breast cancer via interposing inflammation and immunosuppression as an inhibitor of COX-2 and PD-L1
10.1002/anie.202011273 · 2020 · External reference
A dual stimuli-responsive nanoplatform loaded Pt(IV) -Triptolide prodrug for achieving synergistic therapy toward breast cancer
10.1002/adhm.202301328 · ExternalCitation · doi-reference
Recent progress in ferroptosis inducers for cancer therapy
10.1002/adma.201904197 · ExternalCitation · doi-reference
Engineering asymmetric and highly exposed Fe single-atom nanozymes for siMMP13 delivery and ferroptosis inhibition in osteoarthritis therapy
10.1002/adma.202520951 · ExternalCitation · doi-reference
Multispecific Platinum(IV) complex deters breast cancer via interposing inflammation and immunosuppression as an inhibitor of COX-2 and PD-L1
10.1002/anie.202011273 · ExternalCitation · doi-reference
Rational design of Type-I photodynamic agents
10.1002/anie.202509416 · ExternalCitation · doi-reference
Ferroptosis of T cell in inflammation and tumour immunity
10.1002/ctm2.70253 · ExternalCitation · doi-reference
A new oxaliplatin(IV) prodrug inducing ferroptosis through a triple-pathway mechanism and activating anti-cancer immunity
10.1007/s11426-024-2683-9 · ExternalCitation · doi-reference
Understanding the novel approach of nanoferroptosis for cancer therapy
10.1007/s40820-024-01399-0 · ExternalCitation · doi-reference
Cationization to boost both type I and type II ROS generation for photodynamic therapy
10.1016/j.biomaterials.2021.121255 · ExternalCitation · doi-reference
A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy
10.1016/j.biomaterials.2024.122574 · ExternalCitation · doi-reference
The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions
10.1016/j.ccell.2024.03.011 · ExternalCitation · doi-reference
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest
10.1016/j.ccell.2025.09.010 · ExternalCitation · doi-reference
Sublethal cytochrome c release generates drug-tolerant persister cells
10.1016/j.cell.2022.07.025 · ExternalCitation · doi-reference
Human hematopoietic stem cell vulnerability to ferroptosis
10.1016/j.cell.2023.01.020 · ExternalCitation · doi-reference
PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8(+) T cell ferroptosis
10.1016/j.immuni.2024.08.003 · ExternalCitation · doi-reference
Sickle cell disease induces chromatin introversion and ferroptosis in CD8(+) T cells to suppress anti-tumor immunity
10.1016/j.immuni.2025.04.020 · ExternalCitation · doi-reference
Synthesis, photophysical and anticancer properties of mitochondria-targeted phosphorescent cyclometalated iridium(III) N-heterocyclic carbene complexes
10.1016/j.jinorgbio.2019.110976 · ExternalCitation · doi-reference
Iridium(III) complexes as type I photosensitizers for hypoxic two-photon photodynamic therapy
10.1016/j.jinorgbio.2025.113006 · ExternalCitation · doi-reference
Stressed to death: mitochondrial stress responses connect respiration and apoptosis in cancer
10.1016/j.molcel.2022.07.012 · ExternalCitation · doi-reference
Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: perspectives for immunotherapy of SCLC
10.1016/j.semcancer.2022.03.009 · ExternalCitation · doi-reference
In-Cell NAD(P)H photocatalysis with a metal complex for photocatalytic anticancer therapy
10.1021/acs.accounts.5c00455 · ExternalCitation · doi-reference
Efficient enhancement of the visible-light absorption of cyclometalated Ir(III) complexes triplet photosensitizers with Bodipy and applications in photooxidation and triplet-triplet annihilation upconversion
10.1021/ic302210b · ExternalCitation · doi-reference
Tailoring photosensitive ROS for advanced photodynamic therapy
10.1038/s12276-021-00599-7 · ExternalCitation · doi-reference
Neoantigens: promising targets for cancer therapy
10.1038/s41392-022-01270-x · ExternalCitation · doi-reference
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
10.1038/s41392-023-01720-0 · ExternalCitation · doi-reference
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
10.1038/s41392-024-01769-5 · ExternalCitation · doi-reference
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer
10.1038/s41392-024-01772-w · ExternalCitation · doi-reference
Exploring treatment options in cancer: tumor treatment strategies
10.1038/s41392-024-01856-7 · ExternalCitation · doi-reference
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria
10.1038/s41419-024-07237-w · ExternalCitation · doi-reference
Wavelength engineerable porous organic polymer photosensitizers with protonation triggered ROS generation
10.1038/s41467-023-37156-x · ExternalCitation · doi-reference
DHODH modulates immune evasion of cancer cells via CDP-choline dependent regulation of phospholipid metabolism and ferroptosis
10.1038/s41467-025-59307-y · ExternalCitation · doi-reference
A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis
10.1038/s41556-025-01722-w · ExternalCitation · doi-reference
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
10.1038/s41568-024-00674-x · ExternalCitation · doi-reference
Broadening Horizons: the role of ferroptosis in cancer
10.1038/s41571-020-00462-0 · ExternalCitation · doi-reference
The therapeutic potential of targeting regulated non-apoptotic cell death
10.1038/s41573-023-00749-8 · ExternalCitation · doi-reference
Cell death in pancreatic cancer: from pathogenesis to therapy
10.1038/s41575-021-00486-6 · ExternalCitation · doi-reference
Recommendations for robust and reproducible research on ferroptosis
10.1038/s41580-025-00843-2 · ExternalCitation · doi-reference
Ferroptosis of tumour neutrophils causes immune suppression in cancer
10.1038/s41586-022-05443-0 · ExternalCitation · doi-reference
Shedding light on photo-redox catalysis of a NIR iridium(III) complex for high photocytotoxicity against cisplatin resistant ovarian cancer in 3D tumor spheroids
10.1039/d5tb02239h · ExternalCitation · doi-reference
The course of immune stimulation by photodynamic therapy: bridging fundamentals of photochemically induced immunogenic cell death to the enrichment of T-Cell repertoire
10.1111/php.13173 · ExternalCitation · doi-reference
Endothelial heterogeneity in the response to autophagy drives small vessel muscularization in pulmonary hypertension
10.1161/circulationaha.124.068726 · ExternalCitation · doi-reference
Targeting apoptotic pathways for cancer therapy
10.1172/jci179570 · ExternalCitation · doi-reference
Cellular stress response and apoptosis in cancer therapy
10.1182/blood.v98.9.2603 · ExternalCitation · doi-reference
Ferroptotic therapy in cancer: benefits, side effects, and risks
10.1186/s12943-024-01999-9 · ExternalCitation · doi-reference
Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
10.1186/s13045-022-01392-3 · ExternalCitation · doi-reference
Dual-locked targeted alpha-emitter enhanced tumor immunotherapy via Diels-Alder reaction-based self-immolative molecular cage strategy
10.1186/s40779-025-00673-5 · ExternalCitation · doi-reference
Photodynamic priming with triple-receptor targeted nanoconjugates that trigger T cell-mediated immune responses in a 3D in vitro heterocellular model of pancreatic cancer
10.1515/nanoph-2021-0304 · ExternalCitation · doi-reference
VDR activation attenuates renal tubular epithelial cell ferroptosis by regulating Nrf2/HO-1 signaling pathway in diabetic nephropathy
10.4028/b-wjqrp6 · ExternalCitation · doi-reference
