Research graph
References from Inhalation exposure and uptake modeling of particle-associated phthalate: from respiratory deposition and clearance to organ toxicokinetics. Local targets link to admitted publications; unresolved targets remain external evidence.
Overview of known plastic packaging-associated chemicals and their hazards
10.1016/j.scitotenv.2018.10.015 · 2019 · External reference
Human health impacts of exposure to phthalate plasticizers: an overview of reviews
10.1016/j.envint.2021.106903 · 2022 · External reference
In utero exposure to di-(2-ethylhexyl) phthalate decreases mineralocorticoid receptor expression in the adult testis
10.1210/en.2009-0847 · 2009 · External reference
Daily exposure to di(2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice1
10.1095/biolreprod.114.119032 · 2014 · External reference
Effects of uterine and lactational exposure to di-(2-ethylhexyl) phthalate on spatial memory and NMDA receptor of hippocampus in mice
10.1016/j.yhbeh.2015.03.008 · 2015 · External reference
Exposure to diethylhexyl phthalate (DEHP) and monoethylhexyl phthalate (MEHP) promotes the loss of alveolar epithelial phenotype of A549 cells
10.1016/j.toxlet.2018.05.012 · 2018 · External reference
DEHP and DINP induce tissue- and gender-specific disturbances in fatty acid and lipidomic profiles in neonatal mice: a comparative study
10.1021/acs.est.9b04369 · 2019 · External reference
Reproductive effects of phthalates and microplastics on marine mussels based on adverse outcome pathway
10.1021/acs.est.4c12212 · 2025 · External reference
Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP
10.1007/s00204-003-0522-3 · 2004 · External reference
New metabolites of di(2-ethylhexyl)phthalate (DEHP) in human urine and serum after single oral doses of deuterium-labelled DEHP
10.1007/s00204-004-0642-4 · 2005 · External reference
Intravenous exposure to di(2-ethylhexyl)phthalate (DEHP): metabolites of DEHP in urine after a voluntary platelet donation
10.1007/s00204-005-0004-x · 2005 · External reference
Inhalation and dermal uptake of particle and gas-phase phthalates—a human exposure study
10.1021/acs.est.8b03761 · 2018 · External reference
Excretion of urinary metabolites of the phthalate esters DEP and DEHP in 16 volunteers after inhalation and dermal exposure
10.3390/ijerph15112514 · 2018 · External reference
Unresolved reference
2022 · External reference
Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: a bottom up modeling approach
10.1016/j.toxlet.2018.06.1217 · 2018 · External reference
Modeling di (2-ethylhexyl) phthalate (DEHP) and its metabolism in a body’s organs and tissues through different intake pathways into human body
10.3390/ijerph19095742 · 2022 · External reference
A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure
10.1038/s41598-022-05108-y · 2022 · External reference
Predicting regional respiratory tissue and systemic concentrations of orally inhaled drugs through a novel PBPK model
10.1124/dmd.121.000789 · 2022 · External reference
Physiologically based pharmacokinetic modeling for chlorinated paraffins in rats and humans: importance of biliary excretion
10.1021/acs.est.9b03991 · 2020 · External reference
Integration of toxicogenomics and physiologically based pharmacokinetic modeling in human health risk assessment of perfluorooctane sulfonate
10.1021/acs.est.1c06479 · 2022 · External reference
Development of a physiologically based pharmacokinetic (PBPK) model for F-53B in pregnant mice and its extrapolation to humans
10.1021/acs.est.4c05405 · 2024 · External reference
Development of a physiologically based pharmacokinetic model for inorganic mercury salts in rodents and humans and its application in the derivation of health-based toxicity metrics
10.1021/acs.est.5c00627 · 2025 · External reference
Modeling the bioaccessibility of inhaled semivolatile organic compounds in the human respiratory tract
10.1016/j.ijheh.2019.113436 · 2020 · External reference
Long-term inhalation exposure: a model for phthalate accumulation in the respiratory tract
10.1016/j.ecoenv.2024.117207 · 2024 · External reference
Use of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry comparisons of ester vapors
10.1006/taap.2002.9451 · 2002 · External reference
Development of a hybrid CFD-PBPK model to predict the transport of xenon gas around a human respiratory system to systemic regions
10.1016/j.heliyon.2019.e01461 · 2019 · External reference
CFPD-PK simulation of inhaled delta-9-tetrahydrocannabinol aerosol dynamics: transport, deposition, and translocation in a mouth-to-G10 subject-specific human airway
10.1016/j.jaerosci.2024.106334 · 2024 · External reference
Comprehensive integration framework of CFD – local and whole body hybrid PBPK in indoor chemical exposure modeling: an inhalation exposure study
10.1016/j.scs.2025.106463 · 2025 · External reference
Impact of mold growth on di(2-ethylhexyl) phthalate emission from moist wallpaper
10.1016/j.heliyon.2022.e10404 · 2022 · External reference
A novel method for assessing indoor di 2-ethylhexyl phthalate (DEHP) contamination and exposure based on dust-phase concentration
10.1016/j.chemosphere.2023.140994 · 2024 · External reference
Exposure to SVOCs from inhaled particles: impact of desorption
10.1021/acs.est.6b05864 · 2017 · External reference
Mucociliary respiratory epithelium integrity in molecular defense and susceptibility to pulmonary viral infections
10.3390/biology10020095 · 2021 · External reference
In vivo detection of pulmonary mucociliary clearance: present challenges and future directions
10.1183/16000617.0073-2024 · 2024 · External reference
Effect of transient breathing cycle on the deposition of micro and nanoparticles on respiratory walls
10.1016/j.cmpb.2023.107501 · 2023 · External reference
Computational fluid-particle dynamics modeling of ultrafine to coarse particles deposition in the human respiratory system, down to the terminal bronchiole
10.1016/j.cmpb.2023.107589 · 2023 · External reference
Computational fluid-particle dynamics method in predicting the particle aspiration and deposition in the comprehensive monkey respiratory tract
2025 · External reference
SARS-CoV-2 dynamics in the mucus layer of the human upper respiratory tract based on host–cell dynamics
10.3390/su14073896 · 2022 · External reference
In silico identification of viral loads in cough-generated droplets – seamless integrated analysis of CFPD-HCD-EWF
10.1016/j.cmpb.2024.108073 · 2024 · External reference
Allometric comparison of viral dynamics in the nasal cavity-nasopharyngeal mucus layer of human and rhesus monkey by CFD-HCD approach
10.1016/j.cmpb.2024.108354 · 2024 · External reference
A numerical investigation of the potential effects of e-cigarette smoking on local tissue dosimetry and the deterioration of indoor air quality
10.1111/ina.12666 · 2020 · External reference
A pilot numerical study of odorant transport to the olfactory region during sensory evaluations following ISO 16000-28
10.1016/j.buildenv.2023.110868 · 2023 · External reference
Experimental and computational predictions of odorant transport dynamics from indoor environment to olfactory tissue
10.1016/j.scs.2025.106397 · 2025 · External reference
Respiratory retention of 35 toxicants from E-cigarette gaseous emissions: comprehensive numerical study
10.1016/j.buildenv.2025.113663 · 2025 · External reference
Development of a computational fluid dynamics model for mucociliary clearance in the nasal cavity
10.1016/j.jbiomech.2019.01.015 · 2019 · External reference
Prediction of nasal spray drug absorption influenced by mucociliary clearance
10.1371/journal.pone.0246007 · 2021 · External reference
Computational analysis of a 3D mucociliary clearance model predicting nasal drug uptake
10.1016/j.jaerosci.2021.105757 · 2021 · External reference
Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa
10.1016/j.compchemeng.2023.108458 · 2023 · External reference
Numerical investigation of mucociliary clearance using power law and thixotropic mucus layers under discrete and continuous cilia motion
10.1007/s10237-022-01645-7 · 2023 · External reference
Nonlinear simulation of mucociliary clearance: a three- dimensional study
10.1016/j.jnnfm.2021.104727 · 2022 · External reference
Investigation of drug ciliary attachment dynamics and their impact on nanoparticle therapeutics in airway surface liquid
10.1164/ajrccm.2025.211.abstracts.a3079 · 2025 · External reference
The rate of solution of solid substances in their own solutions
10.1021/ja02086a003 · 1897 · External reference
Absorption and clearance of pharmaceutical aerosols in the human nose: development of a CFD model
10.1089/jamp.2015.1252 · 2016 · External reference
Absorption and clearance of pharmaceutical aerosols in the human nose: effects of nasal spray suspension particle size and properties
10.1007/s11095-015-1837-5 · 2016 · External reference
CFD-PK model for nasal suspension sprays: validation with human adult in vivo data for triamcinolone acetonide
10.1016/j.ijpharm.2024.124660 · 2024 · External reference
CFD-DEM modeling of particle dissolution behavior in stirred tanks
10.1016/j.powtec.2024.119894 · 2024 · External reference
CFD-DEM study of heat transfer and particle dissolution in stirred tanks
10.1016/j.ces.2025.121858 · 2025 · External reference
Simulation of drug transport in airway surface liquid considering mucus flow and ciliary interaction
10.1038/s41598-025-16822-8 · 2025 · External reference
Unresolved reference
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Unresolved reference
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Solubilities and surface activities of phthalates investigated by surface tension measurements
10.1002/etc.5620200113 · 2001 · External reference
Transient absorption of inhaled vapors into a multilayer mucus–tissue–blood system
10.1007/s10439-009-9808-9 · 2010 · External reference
Development of a CFD boundary condition to model transient vapor absorption in the respiratory airways
10.1115/1.4001045 · 2010 · External reference
Unresolved reference
External reference
Mechanosensitive ATP release maintains proper mucus hydration of airways
10.1126/scisignal.2003755 · 2013 · External reference
Physicochemical properties of mucus and their impact on transmucosal drug delivery
10.1016/j.ijpharm.2017.09.018 · 2017 · External reference
Diffusion of nonelectrolytes in the canine trachea: effect of tight junction
10.1152/jappl.1996.80.5.1687 · 1996 · External reference
10.1111/j.1365-2605.2005.00607.x
10.1111/j.1365-2605.2005.00607.x · External reference
Structure and function relationships of mucociliary clearance in human and rat airways
10.1038/s41467-025-57667-z · 2025 · External reference
Barrier function of airway tract epithelium
10.4161/tisb.24997 · 2013 · External reference
Cilia and mucociliary clearance
10.1101/cshperspect.a028241 · 2017 · External reference
Roles of airway and intestinal epithelia in responding to pathogens and maintaining tissue homeostasis
10.3389/fcimb.2024.1346087 · 2024 · External reference
Inhalation bioacessibility and lung cell penetration of indoor PM2.5-bound PAEs and its implication in risk assessment
10.1016/j.envpol.2023.121216 · 2023 · External reference
Inhalation bioaccessibility of multi-class organic pollutants associated to atmospheric PM2.5: correlation with PM2.5 properties and health risk assessment
10.1016/j.envpol.2022.119577 · 2022 · External reference
Lipid-based mucus penetrating nanoparticles and their biophysical interactions with pulmonary mucus layer
10.1016/j.ejpb.2020.01.017 · 2020 · External reference
Mucin biopolymers and their barrier function at airway surfaces
10.1021/acs.langmuir.0c02410 · 2020 · External reference
Size shifting of solid lipid nanoparticle system triggered by alkaline phosphatase for site specific mucosal drug delivery
10.1016/j.ejpb.2021.03.012 · 2021 · External reference
Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity
2023 · External reference
Development of nanoparticle-based mucosal drug delivery systems for controlling pharmacokinetic behaviors
10.1248/bpb.b25-00071 · 2025 · External reference
Update on macrophage clearance of inhaled micro- and nanoparticles
10.1089/jamp.2009.0797 · 2010 · External reference
Translocation of gold nanoparticles across the lung epithelial tissue barrier: combining in vitro and in silico methods to substitute in vivo experiments
10.1186/s12989-015-0090-8 · 2015 · External reference
Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver
10.1080/10408440600779065 · 2006 · External reference
In vitro intestinal and hepatic metabolism of di(2-ethylhexyl) phthalate (DEHP) in human and rat
10.1016/j.tiv.2013.03.012 · 2013 · External reference
Hydrolysis of dibutyl phthalate and di(2-ethylhexyl) phthalate in human liver, small intestine, kidney, and lung: an in vitro analysis using organ subcellular fractions and recombinant carboxylesterases
10.1016/j.cbi.2023.110353 · 2023 · External reference
Secondary indoor air pollution and passive smoking associated with cannabis smoking using electric cigarette device–demonstrative in silico study
10.1371/journal.pcbi.1009004 · 2021 · External reference
Toxic effects of DEHP and MEHP on gut-liver axis in rats via intestinal flora and metabolomics
10.1016/j.isci.2024.111135 · 2024 · External reference
Determination of phthalates in particulate matter and gaseous phase emitted into the air of the working environment
10.1007/s13762-019-02435-y · 2020 · External reference
The glymphatic system: a beginner’s guide
10.1007/s11064-015-1581-6 · 2015 · External reference
The lymphatic system in the brain clearance mechanisms - new therapeuticperspectives for alzheimer’s disease
10.2174/1570159x20666220411091332 · 2023 · External reference
Di-2-ethylhexyl phthalate (DEHP) toxicity: organ-specific impacts and human-relevant findings in animal models & humans - review
10.23937/2572-4061.1510062 · 2025 · External reference
