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References from The role of α2-adrenoceptors in podocyte damage caused by puromycin aminonucleoside-induced nephrotic syndrome in rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Glomerulosclerosis and progression: effect of subantihypertensive doses of alpha and beta blockers
10.1046/j.1523-1755.2001.00936.x · 2001 · External reference
Role of the β(2)-adrenergic receptor in podocyte injury and recovery
10.1007/s43440-024-00594-5 · 2024 · External reference
Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury
10.1016/j.kint.2019.03.023 · 2019 · External reference
Discovery of kidney disease targets using multimodal human podocyte injury models
10.1016/j.stemcr.2026.102868 · 2026 · External reference
Renin secretion and total body sodium: pathways of integrative control
10.1111/j.1440-1681.2009.05316.x · 2010 · External reference
Sympathetic overactivity in patients with chronic renal failure
10.1056/nejm199212313272704 · 1992 · External reference
Studies of the mechanism of oliguria in a model of unilateral acute renal failure
10.1172/jci107705 · 1974 · External reference
Transforming growth factor β1-induced apoptosis in podocytes via the extracellular signal-regulated kinase-mammalian target of Rapamycin complex 1-NADPH oxidase 4 axis
10.1074/jbc.m115.703116 · 2015 · External reference
A fatal case report of acute yohimbine intoxication
10.1007/s11419-019-00512-y · 2020 · External reference
Renal denervation has blood pressure-independent protective effects on kidney and heart in a rat model of chronic kidney disease
10.1038/ki.2014.220 · 2015 · External reference
The role of renal denervation for the treatment of hypertension in patients with chronic kidney disease: a position paper of the Italian Society of Nephrology
10.1007/s40620-025-02406-2 · 2025 · External reference
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response
10.1371/journal.pone.0004414 · 2009 · External reference
Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease
10.1038/ki.2011.306 · 2012 · External reference
Diverse role of TGF-β in kidney disease
10.3389/fcell.2020.00123 · 2020 · External reference
Inhibition of α(2)-adrenoceptor is renoprotective in 5/6 nephrectomy-induced chronic kidney injury rats
10.1016/j.jphs.2020.11.001 · 2021 · External reference
Renal denervation in moderate to severe CKD
10.1681/asn.2011111062 · 2012 · External reference
Nephrotic syndrome in adults
10.1136/bmj.39576.709711.80 · 2008 · External reference
Prioritization of bioactive compounds envisaging yohimbine as a multi targeted anticancer agent: insight from molecular docking and molecular dynamics simulation
10.1080/07391102.2022.2158137 · 2023 · External reference
Renal sympathetic nerve activation via α(2)-adrenergic receptors in chronic kidney disease progression
10.23876/j.krcp.18.0143 · 2019 · External reference
Yohimbine treatment improves pulmonary fibrosis by attenuating the inflammation and oxidative stress via modulating the MAPK pathway
10.1016/j.bcp.2024.116613 · 2024 · External reference
Renal nerves drive interstitial fibrogenesis in obstructive nephropathy
10.1681/asn.2012070678 · 2013 · External reference
Renal denervation prevents long-term sequelae of ischemic renal injury
10.1038/ki.2014.300 · 2015 · External reference
Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase
10.1038/ki.2011.282 · 2011 · External reference
Sympathetic hyperactivity in chronic renal failure: a wake-up call
10.1097/01.asn.0000113320.57127.b9 · 2004 · External reference
The podocyte’s response to stress: the enigma of foot process effacement
10.1152/ajprenal.00478.2012 · 2013 · External reference
Integrating traditional Chinese medicine in the management of podocytopathies: pathological insights and therapeutic
2025 · External reference
IL-20 in acute kidney injury: role in pathogenesis and potential as a therapeutic target
10.3390/ijms21031009 · 2020 · External reference
Oxidative stress and inflammation in renal fibrosis: novel molecular mechanisms and therapeutic targets
10.1016/j.cbi.2025.111784 · 2025 · External reference
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease
10.1186/s13020-024-00903-3 · 2024 · External reference
Role of podocyte injury in glomerulosclerosis
10.1007/978-981-13-8871-2_10 · 2019 · External reference
Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension
10.1161/hypertensionaha.112.193870 · 2012 · External reference
The glomerular filtration barrier: components and crosstalk
2012 · External reference
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway
10.1038/s41401-023-01148-w · 2024 · External reference
Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy
10.3389/fphar.2022.969930 · 2022 · External reference
Yohimbine hydrochloride ameliorates collagen type-II-induced arthritis targeting oxidative stress and inflammatory cytokines in Wistar rats
10.1002/tox.22264 · 2017 · External reference
Multifaced Nature of Yohimbine-A promising therapeutic potential or a risk?
10.3390/ijms252312856 · 2024 · External reference
Calcium channel blocker in patients with chronic kidney disease
10.1007/s10157-021-02153-1 · 2022 · External reference
Mesenchymal stromal cells induce podocyte protection in the Puromycin Injury model
10.1038/s41598-019-55284-7 · 2019 · External reference
Roles of the podocyte in glomerular function
10.1152/ajprenal.2000.278.2.f173 · 2000 · External reference
Contribution of the renal nerves to hypertension in a rabbit model of chronic kidney disease
10.1161/hypertensionaha.120.15769 · 2020 · External reference
Renal denervation in end-stage renal disease: current evidence and perspectives
10.1007/s40292-023-00621-1 · 2024 · External reference
Renal denervation in patients with chronic kidney disease: current evidence and future perspectives
10.1093/ndt/gfac189 · 2023 · External reference
Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation
10.1046/j.1523-1755.2000.00213.x · 2000 · External reference
Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway
10.1016/j.phymed.2023.155182 · 2024 · External reference
Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models
2016 · External reference
Subcellular distribution of α2-adrenoceptor subtypes in the rodent kidney
10.1007/s00441-021-03558-w · 2022 · External reference
Renoprotective effect of yohimbine on ischaemia/reperfusion-induced acute kidney injury through α2C-adrenoceptors in rats
10.1016/j.ejphar.2016.03.059 · 2016 · External reference
Post-treatment with JP-1302 protects against renal ischemia/reperfusion-induced acute kidney injury in rats
10.1016/j.jphs.2018.12.008 · 2019 · External reference
Yohimbine ameliorates lipopolysaccharide-induced acute kidney injury in rats
10.1016/j.ejphar.2020.172917 · 2020 · External reference
Associations between the concentrations of CD68, TGF-β1, renal injury index and prognosis in glomerular diseases
10.3892/etm.2020.9184 · 2020 · External reference
Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis
10.1080/13880209.2020.1711782 · 2020 · External reference
Mechanisms of podocyte detachment, podocyturia, and risk of progression of glomerulopathies
10.1159/000507997 · 2020 · External reference
GDF-15 suppresses Puromycin aminonucleoside-induced podocyte injury by reducing endoplasmic reticulum stress and glomerular inflammation
10.3390/cells13070637 · 2024 · External reference
Efficacy and safety of renal denervation for hypertension in patients with chronic kidney disease: a meta-analysis
10.1080/02656736.2021.1916100 · 2021 · External reference
Yohimbine hydrochloride inhibits benign prostatic hyperplasia by downregulating steroid 5α-reductase type 2
10.1016/j.ejphar.2021.174334 · 2021 · External reference
Yohimbine hydrochloride ameliorates collagen type-II-induced arthritis targeting oxidative stress and inflammatory cytokines in Wistar rats
10.1002/tox.22264 · ExternalCitation · doi-reference
Role of podocyte injury in glomerulosclerosis
10.1007/978-981-13-8871-2_10 · ExternalCitation · doi-reference
Subcellular distribution of α2-adrenoceptor subtypes in the rodent kidney
10.1007/s00441-021-03558-w · ExternalCitation · doi-reference
Calcium channel blocker in patients with chronic kidney disease
10.1007/s10157-021-02153-1 · ExternalCitation · doi-reference
A fatal case report of acute yohimbine intoxication
10.1007/s11419-019-00512-y · ExternalCitation · doi-reference
Renal denervation in end-stage renal disease: current evidence and perspectives
10.1007/s40292-023-00621-1 · ExternalCitation · doi-reference
The role of renal denervation for the treatment of hypertension in patients with chronic kidney disease: a position paper of the Italian Society of Nephrology
10.1007/s40620-025-02406-2 · ExternalCitation · doi-reference
Role of the β(2)-adrenergic receptor in podocyte injury and recovery
10.1007/s43440-024-00594-5 · ExternalCitation · doi-reference
Yohimbine treatment improves pulmonary fibrosis by attenuating the inflammation and oxidative stress via modulating the MAPK pathway
10.1016/j.bcp.2024.116613 · ExternalCitation · doi-reference
Oxidative stress and inflammation in renal fibrosis: novel molecular mechanisms and therapeutic targets
10.1016/j.cbi.2025.111784 · ExternalCitation · doi-reference
Renoprotective effect of yohimbine on ischaemia/reperfusion-induced acute kidney injury through α2C-adrenoceptors in rats
10.1016/j.ejphar.2016.03.059 · ExternalCitation · doi-reference
Yohimbine ameliorates lipopolysaccharide-induced acute kidney injury in rats
10.1016/j.ejphar.2020.172917 · ExternalCitation · doi-reference
Yohimbine hydrochloride inhibits benign prostatic hyperplasia by downregulating steroid 5α-reductase type 2
10.1016/j.ejphar.2021.174334 · ExternalCitation · doi-reference
Post-treatment with JP-1302 protects against renal ischemia/reperfusion-induced acute kidney injury in rats
10.1016/j.jphs.2018.12.008 · ExternalCitation · doi-reference
Inhibition of α(2)-adrenoceptor is renoprotective in 5/6 nephrectomy-induced chronic kidney injury rats
10.1016/j.jphs.2020.11.001 · ExternalCitation · doi-reference
Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury
10.1016/j.kint.2019.03.023 · ExternalCitation · doi-reference
Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway
10.1016/j.phymed.2023.155182 · ExternalCitation · doi-reference
Discovery of kidney disease targets using multimodal human podocyte injury models
10.1016/j.stemcr.2026.102868 · ExternalCitation · doi-reference
Selective albuminuria via podocyte albumin transport in puromycin nephrotic rats is attenuated by an inhibitor of NADPH oxidase
10.1038/ki.2011.282 · ExternalCitation · doi-reference
Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease
10.1038/ki.2011.306 · ExternalCitation · doi-reference
Renal denervation has blood pressure-independent protective effects on kidney and heart in a rat model of chronic kidney disease
10.1038/ki.2014.220 · ExternalCitation · doi-reference
Renal denervation prevents long-term sequelae of ischemic renal injury
10.1038/ki.2014.300 · ExternalCitation · doi-reference
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway
10.1038/s41401-023-01148-w · ExternalCitation · doi-reference
Mesenchymal stromal cells induce podocyte protection in the Puromycin Injury model
10.1038/s41598-019-55284-7 · ExternalCitation · doi-reference
Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation
10.1046/j.1523-1755.2000.00213.x · ExternalCitation · doi-reference
Glomerulosclerosis and progression: effect of subantihypertensive doses of alpha and beta blockers
10.1046/j.1523-1755.2001.00936.x · ExternalCitation · doi-reference
Sympathetic overactivity in patients with chronic renal failure
10.1056/nejm199212313272704 · ExternalCitation · doi-reference
Transforming growth factor β1-induced apoptosis in podocytes via the extracellular signal-regulated kinase-mammalian target of Rapamycin complex 1-NADPH oxidase 4 axis
10.1074/jbc.m115.703116 · ExternalCitation · doi-reference
Efficacy and safety of renal denervation for hypertension in patients with chronic kidney disease: a meta-analysis
10.1080/02656736.2021.1916100 · ExternalCitation · doi-reference
Prioritization of bioactive compounds envisaging yohimbine as a multi targeted anticancer agent: insight from molecular docking and molecular dynamics simulation
10.1080/07391102.2022.2158137 · ExternalCitation · doi-reference
Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis
10.1080/13880209.2020.1711782 · ExternalCitation · doi-reference
Renal denervation in patients with chronic kidney disease: current evidence and future perspectives
10.1093/ndt/gfac189 · ExternalCitation · doi-reference
Sympathetic hyperactivity in chronic renal failure: a wake-up call
10.1097/01.asn.0000113320.57127.b9 · ExternalCitation · doi-reference
Renin secretion and total body sodium: pathways of integrative control
10.1111/j.1440-1681.2009.05316.x · ExternalCitation · doi-reference
Nephrotic syndrome in adults
10.1136/bmj.39576.709711.80 · ExternalCitation · doi-reference
The podocyte’s response to stress: the enigma of foot process effacement
10.1152/ajprenal.00478.2012 · ExternalCitation · doi-reference
Roles of the podocyte in glomerular function
10.1152/ajprenal.2000.278.2.f173 · ExternalCitation · doi-reference
Mechanisms of podocyte detachment, podocyturia, and risk of progression of glomerulopathies
10.1159/000507997 · ExternalCitation · doi-reference
Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension
10.1161/hypertensionaha.112.193870 · ExternalCitation · doi-reference
Contribution of the renal nerves to hypertension in a rabbit model of chronic kidney disease
10.1161/hypertensionaha.120.15769 · ExternalCitation · doi-reference
Studies of the mechanism of oliguria in a model of unilateral acute renal failure
10.1172/jci107705 · ExternalCitation · doi-reference
Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease
10.1186/s13020-024-00903-3 · ExternalCitation · doi-reference
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response
10.1371/journal.pone.0004414 · ExternalCitation · doi-reference
Renal denervation in moderate to severe CKD
10.1681/asn.2011111062 · ExternalCitation · doi-reference
Renal nerves drive interstitial fibrogenesis in obstructive nephropathy
10.1681/asn.2012070678 · ExternalCitation · doi-reference
Renal sympathetic nerve activation via α(2)-adrenergic receptors in chronic kidney disease progression
10.23876/j.krcp.18.0143 · ExternalCitation · doi-reference
Diverse role of TGF-β in kidney disease
10.3389/fcell.2020.00123 · ExternalCitation · doi-reference
Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy
10.3389/fphar.2022.969930 · ExternalCitation · doi-reference
GDF-15 suppresses Puromycin aminonucleoside-induced podocyte injury by reducing endoplasmic reticulum stress and glomerular inflammation
10.3390/cells13070637 · ExternalCitation · doi-reference
IL-20 in acute kidney injury: role in pathogenesis and potential as a therapeutic target
10.3390/ijms21031009 · ExternalCitation · doi-reference
Multifaced Nature of Yohimbine-A promising therapeutic potential or a risk?
10.3390/ijms252312856 · ExternalCitation · doi-reference
Associations between the concentrations of CD68, TGF-β1, renal injury index and prognosis in glomerular diseases
10.3892/etm.2020.9184 · ExternalCitation · doi-reference
