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References from Polydatin Encapsulated in Human Serum Albumin Nanoparticles Attenuates Oxidative Damage and Protects Rotenone-Induced Neuroblastoma cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy
10.1016/j.neuint.2020.104671 · 2020 · External reference
Prevalence, incidence, and mortality of PD: a door-to-door survey in Ilan county, Taiwan
10.1212/wnl.57.9.1679 · 2001 · External reference
Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson's disease
10.1186/1750-1326-10-4 · 2015 · External reference
Polydatin and Nicotinamide Rescue the Cellular Phenotype of Mitochondrial Diseases by Mitochondrial Unfolded Protein Response (mtUPR) Activation
10.3390/biom14050598 · 2024 · External reference
Treatment of patients with essential tremor
10.1016/s1474-4422(10)70322-7 · 2011 · External reference
The role of oxidative stress in Parkinson's disease
10.3233/jpd-130230 · 2013 · External reference
Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions
10.1038/s41392-023-01353-3 · 2023 · External reference
Albumin-based nanoparticles as potential controlled release drug delivery systems
10.1016/j.jconrel.2011.07.031 · 2012 · External reference
The Neuroprotective Role of Polydatin: Neuropharmacological Mechanisms, Molecular Targets, Therapeutic Potentials, and Clinical Perspective
10.3390/molecules26195985 · 2021 · External reference
Nitrite and nitrate measurement by Griess reagent in human plasma: evaluation of interferences and standardization
10.1016/s0076-6879(07)00823-3 · 2008 · External reference
Oscillatory activity in the basal ganglia and deep brain stimulation
10.1002/mds.26714 · 2017 · External reference
Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3β-Nrf2/NF-κB Signaling Axis
10.3389/fimmu.2018.02527 · 2018 · External reference
Polystyrene nanoplastic exposure induces excessive mitophagy by activating AMPK/ULK1 pathway in differentiated SH-SY5Y cells and dopaminergic neurons in vivo
10.1186/s12989-023-00556-4 · 2023 · External reference
Rotenone-Induced Model of Parkinson's Disease: Beyond Mitochondrial Complex I Inhibition
10.1007/s12035-022-03193-8 · 2023 · External reference
Current trends in etiology, prognosis and therapeutic aspects of Parkinson's disease: a review
2017 · External reference
Polydatin: Pharmacological Mechanisms, Therapeutic Targets, Biological Activities, and Health Benefits
10.3390/molecules27196474 · 2022 · External reference
Polydatin: Pharmacological Mechanisms, Therapeutic Targets, Biological Activities, and Health Benefits
10.3390/molecules27196474 · 2022 · External reference
ZLN005 Alleviates the Dopaminergic Degeneration via PGC-1alpha-Mediated Mitochondrial Homeostasis in Parkinson's Disease
10.1007/s12035-025-05612-y · 2025 · External reference
Human serum albumin (HSA) nanoparticles: reproducibility of preparation process and kinetics of enzymatic degradation
10.1016/j.ijpharm.2007.06.028 · 2008 · External reference
Human Serum Albumin-Based Nanoparticle-Mediated In Vitro Gene Delivery
10.1371/journal.pone.0107603 · 2014 · External reference
Neuroprotective effects of polyphyllin VI against rotenone-induced toxicity in SH-SY5Y cells
10.1016/j.brainres.2024.148824 · 2024 · External reference
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
10.1074/jbc.m210432200 · 2003 · External reference
ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis
10.1007/s12035-025-04824-6 · 2025 · External reference
Nanocarriers for effective nutraceutical delivery to the brain
10.1016/j.neuint.2020.104851 · 2020 · External reference
Decitabine enclosed biotin-zein conjugated nanoparticles: synthesis, characterization, in vitro and in vivo evaluation
2024 · External reference
Dopaminergic neuron-specific oxidative stress caused by dopamine itself
2008 · External reference
Human serum albumin nanoparticles for efficient delivery of Cu, Zn superoxide dismutase gene
2007 · External reference
Neurotrophic function of phytochemicals for neuroprotection in aging and neurodegenerative disorders: modulation of intracellular signaling and gene expression
10.1007/s00702-017-1797-5 · 2017 · External reference
Albumin-Based Nanocarriers for the Simultaneous Delivery of Antioxidant Gene and Phytochemical to Combat Oxidative Stress
10.3389/fcell.2022.846175 · 2022 · External reference
A Simple Microplate Assay for Reactive Oxygen Species Generation and Rapid Cellular Protein Normalization
10.21769/bioprotoc.3877 · 2021 · External reference
Alzheimer's disease and Parkinson's disease
10.1056/nejm2003ra020003 · 2003 · External reference
New insights into the function and regulation of mitochondrial fission
10.1016/j.bbamcr.2013.02.002 · 2013 · External reference
Synthesis and cytotoxicity against tumor cells of pincer N-heterocyclic ligands and their transition metal complexes
10.1039/d1ra05918a · 2021 · External reference
Neuropathology of the Basal Ganglia in SNCA Transgenic Rat Model of Parkinson's Disease: Involvement of Parvalbuminergic Interneurons and Glial-Derived Neurotropic Factor
10.3390/ijms231710126 · 2022 · External reference
Anti-proliferate and apoptosis triggering potential of methotrexate-transferrin conjugate encapsulated PLGA nanoparticles with enhanced cellular uptake by high-affinity folate receptors
10.1080/21691401.2018.1468768 · 2018 · External reference
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
10.1038/nprot.2006.378 · 2006 · External reference
The Impairments of alpha-Synuclein and Mechanistic Target of Rapamycin in Rotenone-Induced SH-SY5Y Cells and Mice Model of Parkinson's Disease
10.3389/fnins.2019.01028 · 2019 · External reference
Polydatin Prevents Electron Transport Chain Dysfunction and ROS Overproduction Paralleled by an Improvement in Lipid Peroxidation and Cardiolipin Levels in Iron-Overloaded Rat Liver Mitochondria
10.3390/ijms252011104 · 2024 · External reference
Challenges in the diagnosis of Parkinson's disease
10.1016/s1474-4422(21)00030-2 · 2021 · External reference
Parkinson's Disease: Cells Succumbing to Lifelong Dopamine-Related Oxidative Stress and Other Bioenergetic Challenges
10.3390/ijms25042009 · 2024 · External reference
Protective effects of polydatin amphiphilic chitosan nanocarriers against an aluminum chloride-induced model of Alzheimer's disease in rats: relevance to its anti-inflammatory and antioxidant effects
10.1007/s00210-024-03696-2 · 2025 · External reference
Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications
10.1016/j.fct.2020.111714 · 2020 · External reference
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons
10.1016/j.neuint.2020.104815 · 2020 · External reference