References

Pichia pastoris: a highly successful expression system for optimal synthesis of heterologous proteins

10.1002/jcp.29583 · 2020 · External reference

Industrial production of proteins with Pichia pastoris-Komagataella phaffii

10.3390/biom13030441 · 2023 · External reference

10.3389/fmicb.2022.1059777

10.3389/fmicb.2022.1059777 · External reference

10.3389/fmicb.2014.00085

10.3389/fmicb.2014.00085 · External reference

A programmable high-expression yeast platform responsive to user-defined signals

2022 · External reference

Enhancing the production of recombinant acidic α-amylase and phytase in Pichia pastoris under dual promoters [constitutive (GAP) and inducible (AOX)] in mixed fed batch high cell density cultivation

10.1016/j.procbio.2016.07.027 · 2016 · External reference

Expression of recombinant proteins in Pichia pastoris

10.1007/s12010-007-0003-x · 2007 · External reference

Practical methods for expression of recombinant protein in the Pichia pastoris system

10.1002/cpz1.155 · 2021 · External reference

Safety evaluation of a lipase enzyme preparation, expressed in Pichia pastoris, intended for use in the degumming of edible vegetable oil

10.1016/j.yrtph.2006.02.001 · 2006 · External reference

Improving the thermostability of a fungal GH11 xylanase via site-directed mutagenesis guided by sequence and structural analysis

10.1186/s13068-017-0824-y · 2017 · External reference

A novel phytase from Citrobactergillenii: characterization and expression in Pichia pastoris (Komagataella pastoris)

10.1093/femsle/fnaa217 · 2021 · External reference

High level expression of a xyloglucanase from Rhizomucor miehei in Pichia pastoris for production of xyloglucan oligosaccharides and its application in yoghurt

10.1016/j.ijbiomac.2021.09.035 · 2021 · External reference

Yeast-derived potato patatins: biochemical and biophysical characterization

10.1016/j.foodchem.2021.130984 · 2022 · External reference

Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion

10.1016/j.ymben.2022.08.010 · 2022 · External reference

Design and heterologous expression of a novel dimeric LL37 variant in Pichia pastoris

10.1186/s12934-021-01635-x · 2021 · External reference

Effect and mechanism of signal peptide and maltose on recombinant type III collagen production in Pichia pastoris

10.1007/s00253-023-12579-0 · 2023 · External reference

Advances in engineering methylotrophic yeast for biosynthesis of valuable chemicals from methanol

10.1016/j.cclet.2017.11.015 · 2018 · External reference

Combined strategies for improving the heterologous expression of an alkaline lipase from Acinetobacter radioresistens CMC-1 in Pichia pastoris

10.1016/j.procbio.2013.06.021 · 2013 · External reference

Recycling of a selectable marker with a self-excisable plasmid in Pichia pastoris

2017 · External reference

Autonomously replicating plasmid vector containing Pichia pastoris centromeric DNA

10.1128/aem.02882-17 · 2018 · External reference

Pichia pastoris as a host system for transformations

1985 · External reference

An autonomously replicating sequence for use in a wide range of budding yeasts

10.1111/1567-1364.12123 · 2014 · External reference

Comparative genome-scale analysis of Pichia pastoris variants informs selection of an optimal base strain

10.1002/bit.27209 · 2020 · External reference

Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris

1985 · External reference

Advances in the application of the non-conventional yeast Pichia kudriavzevii in food and Biotechnology industries

10.3390/jof9020170 · 2023 · External reference

Functional characterization of the two alcohol oxidase genes from the yeast pichia pastoris

1989 · External reference

Mit1 Transcription factor mediates methanol signaling and regulates the alcohol oxidase 1 (AOX1) promoter in Pichia pastoris

10.1074/jbc.m115.692053 · 2016 · External reference

PpNrg1 is a transcriptional repressor for glucose and glycerol repression of AOX1 promoter in methylotrophic yeast Pichia pastoris

10.1007/s10529-015-1972-4 · 2016 · External reference

Promoter library designed for fine-tuned gene expression in Pichia pastoris

10.1093/nar/gkn369 · 2008 · External reference

Combined strategies for improving expression of Citrobacter amalonaticus phytase in Pichia pastoris

10.1186/s12896-015-0204-2 · 2015 · External reference

High-efficiency patatin expression strategies in Komagataella phaffii (Pichia pastoris): expression cassette toolbox and regulation of protein secretion

10.1016/j.synbio.2025.01.003 · 2025 · External reference

Enhancing D-lactic acid production by optimizing the expression of D-LDH gene in methylotrophic yeast Komagataella phaffii

10.1186/s13068-024-02596-0 · 2024 · External reference

GAP promoter library for fine-tuning of gene expression in Pichia pastoris

10.1128/aem.02843-10 · 2011 · External reference

Identification and characterization of PGCW14: a novel, strong constitutive promoter of Pichia pastoris

10.1007/s10529-013-1265-8 · 2013 · External reference

Key regulatory elements of a strong constitutive promoter, PGCW14, from Pichia pastoris

10.1007/s10529-013-1312-5 · 2013 · External reference

Isolation of the pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter

10.1016/s0378-1119(96)00675-0 · 1997 · External reference

Recent advances on the GAP promoter derived expression system of Pichia pastoris

10.1007/s11033-008-9359-4 · 2009 · External reference

Role of alpha-factor and the MF alpha 1 alpha-factor precursor in mating in yeast

10.1093/genetics/127.2.299 · 1991 · External reference

Structural characterization of the α-mating factor prepro-peptide for secretion of recombinant proteins in Pichia pastoris

10.1016/j.gene.2016.10.040 · 2017 · External reference

Targeting of proteins for translocation at the endoplasmic reticulum

10.3390/ijms23073773 · 2022 · External reference

Structure of the post-translational protein translocation machinery of the ER membrane

10.1038/s41586-018-0856-x · 2019 · External reference

Expression of hybrid peptide EF-1 in Pichia pastoris, its purification, and antimicrobial characterization

10.3390/molecules25235538 · 2020 · External reference

Expression of the Zebrafish β-defensin 3 mature peptide in Pichia pastoris and its purification and antibacterial activity

10.1134/s0003683817060126 · 2017 · External reference

Design of an improved universal signal peptide based on the α-factor mating secretion signal for enzyme production in yeast

10.1007/s00018-021-03793-y · 2021 · External reference

Avoiding entry into intracellular protein degradation pathways by signal mutations increases protein secretion in Pichia pastoris

10.1111/1751-7915.14061 · 2022 · External reference

Codon optimization of Saccharomyces cerevisiae mating factor alpha prepro-leader to improve recombinant protein production in Pichia pastoris

10.1007/s10529-016-2203-3 · 2016 · External reference

Efficient expression of an alkaline pectin lyase from Bacillus licheniformis in Pichia pastoris

10.1186/s40643-024-00752-w · 2024 · External reference

An improved secretion signal enhances the secretion of model proteins from Pichia pastoris

10.1186/s12934-018-1009-5 · 2018 · External reference

Screening endogenous signal peptides and protein folding factors to promote the secretory expression of heterologous proteins in Pichia pastoris

10.1016/j.jbiotec.2019.06.297 · 2019 · External reference

Potential of the signal peptide derived from the PAS_chr3_0030 gene product for secretory expression of valuable enzymes in Pichia pastoris

10.1128/aem.00296-22 · 2022 · External reference

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

10.1101/gad.824700 · 2000 · External reference

Uniform transitions of the general RNA polymerase II transcription complex

10.1038/nsmb.1903 · 2010 · External reference

An allosteric mechanism of rho-dependent transcription termination

10.1038/nature08669 · 2010 · External reference

Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast

10.1016/j.cell.2013.12.026 · 2014 · External reference

A genome-wide activity assessment of terminator regions in saccharomyces cerevisiae provides a "terminatome" toolbox

10.1021/sb300116y · 2013 · External reference

Exchange of endogenous and heterogeneous yeast terminators in Pichia pastoris to tune mRNA stability and gene expression

10.1093/nar/gkaa1066 · 2020 · External reference

Transcriptional control of gene expression in Pichia pastoris by manipulation of terminators

10.1007/s00253-020-10785-8 · 2020 · External reference

A toolbox of diverse promoters related to methanol utilization: functionally verified parts for heterologous pathway expression in Pichia pastoris

10.1021/acssynbio.5b00199 · 2016 · External reference

Optimization of multiple combinations of early secretion pathways to enhance extracellular protein secretion in Komagataella phaffii

10.1021/acs.jafc.5c03402 · 2025 · External reference

Engineering the early secretory pathway for increased protein secretion in Saccharomyces cerevisiae

10.1016/j.ymben.2019.06.010 · 2019 · External reference

Short synthetic terminators for improved heterologous gene expression in yeast

10.1021/sb5003357 · 2015 · External reference

Yeast terminator function can Be modulated and designed on the basis of predictions of nucleosome occupancy

10.1021/acssynbio.7b00138 · 2017 · External reference

Use of expression-enhancing terminators in Saccharomyces cerevisiae to increase mRNA half-life and improve gene expression control for metabolic engineering applications

10.1016/j.ymben.2013.07.001 · 2013 · External reference

Combined strategies to improve the heterologous expression of glucose oxidase from Aspergillus cristatus in Komagataella phaffii

10.1016/j.bej.2025.109856 · 2025 · External reference

Automated design of thousands of nonrepetitive parts for engineering stable genetic systems

10.1038/s41587-020-0584-2 · 2020 · External reference

Polycistronic cellulase gene expression in Pichia pastoris

10.1007/s13399-021-01765-7 · 2023 · External reference

Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus

10.1111/j.1567-1364.2009.00561.x · 2009 · External reference

A systematical investigation on the genetic stability of multi-copy Pichia pastoris strains

10.1007/s10529-009-9917-4 · 2009 · External reference

Heterologous protein production in methylotrophic yeasts

10.1007/s002530000464 · 2000 · External reference

Heterologous protein expression in the methylotrophic yeast Pichia pastoris

10.1111/j.1574-6976.2000.tb00532.x · 2000 · External reference

Transcription factor Mxr1 promotes the expression of Aox1 by repressing glycerol transporter 1 in Pichia pastoris

10.1093/femsyr/fox015 · 2017 · External reference

Unresolved reference

External reference

Overexpression of the transcriptional activators Mxr1 and Mit1 enhances lactic acid production on methanol in Komagataella phaffii

10.1016/j.ymben.2024.07.013 · 2024 · External reference

Transcriptome and metabolome analyses reveal global behaviour of a genetically engineered methanol-independent Pichia pastoris strain

10.1016/j.procbio.2018.10.014 · 2019 · External reference

Unresolved reference

External reference

Role of eIF2α kinases in translational control and adaptation to cellular stress

10.1101/cshperspect.a032870 · 2018 · External reference

Probing the closed-loop model of mRNA translation in living cells

10.1080/15476286.2015.1017242 · 2015 · External reference

Protein synthesis initiation in eukaryotic cells

10.1101/cshperspect.a033092 · 2018 · External reference

The ribosome in action: tuning of translational efficiency and protein folding

10.1002/pro.2950 · 2016 · External reference

Going beyond the limit: increasing global translation activity leads to increased productivity of recombinant secreted proteins in Pichia pastoris

10.1016/j.ymben.2022.01.010 · 2022 · External reference

Combined strategies for improving the heterologous expression of a novel xylanase from fusarium oxysporum Fo47 in Pichia pastoris

10.1016/j.synbio.2024.03.012 · 2024 · External reference

Spatial expression of the genome: the signal hypothesis at forty

10.1038/nrm3105 · 2011 · External reference

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

10.1038/nature06384 · 2007 · External reference

Pathway engineering facilitates efficient protein expression in Pichia pastoris

10.1007/s00253-022-12139-y · 2022 · External reference

ERO1-PDI redox signaling in health and disease

10.1089/ars.2021.0018 · 2021 · External reference

Defining the mechanism of PDI interaction with disulfide-free amyloidogenic proteins: implications for exogenous protein expression and neurodegenerative disease

10.1016/j.ijbiomac.2021.01.172 · 2021 · External reference

Effects of co-overexpression of secretion helper factors on the secretion of a HSA fusion protein (IL2-HSA) in pichia pastoris

10.1002/yea.3183 · 2016 · External reference

Co-expression of chaperones for improvement of recombinant geobacillus stearothermophilus lipase production in Pichia pastoris

10.1002/bab.70017 · 2025 · External reference

Effect of gene copy number and chaperone coexpression on recombinant hydrophobin HFBI biosurfactant production in Pichia pastoris

10.1002/bit.26982 · 2019 · External reference

Oligosaccharyltransferase structures provide novel insight into the mechanism of asparagine-linked glycosylation in prokaryotic and eukaryotic cells

10.1093/glycob/cwy093 · 2019 · External reference

Engineering of glycosylation in yeast and other fungi: current state and perspectives

10.1007/s00253-010-2721-1 · 2010 · External reference

The unfolded protein response: detecting and responding to fluctuations in the protein-folding capacity of the endoplasmic reticulum

10.1101/cshperspect.a033886 · 2019 · External reference

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

10.1038/16729 · 1999 · External reference

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

10.1083/jcb.200907074 · 2009 · External reference

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

10.1016/s0092-8674(00)80835-1 · 2000 · External reference

Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays

10.1186/1471-2164-9-390 · 2008 · External reference

The impact of ERAD on recombinant protein secretion in Pichia pastoris (syn Komagataella spp.)

10.1099/mic.0.000630 · 2018 · External reference

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

10.1126/science.1254312 · 2014 · External reference

Unfolded proteins are Ire1-activating ligands that directly induce the Unfolded protein response

10.1126/science.1209126 · 2011 · External reference

Endoplasmic stress sensor Ire1 is involved in cytosolic/nuclear protein quality control in Pichia pastoris cells independent of HAC1

10.3389/fmicb.2023.1157146 · 2023 · External reference

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

10.1038/415092a · 2002 · External reference

Translation control of HAC1 by regulation of splicing in saccharomyces cerevisiae

10.3390/ijms20122860 · 2019 · External reference

Getting RIDD of RNA: IRE1 in cell fate regulation

10.1016/j.tibs.2014.02.008 · 2014 · External reference

Regulating unfolded protein response activator HAC1p for production of thermostable raw-starch hydrolyzing α-amylase in Pichia pastoris

10.1007/s00449-016-1701-y · 2017 · External reference

Optimizing expression of Nanobody® molecules in Pichia pastoris through co-expression of auxiliary proteins under methanol and methanol-free conditions

10.1186/s12934-023-02132-z · 2023 · External reference

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

10.1074/jbc.m402468200 · 2004 · External reference

Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking

10.1016/j.febslet.2011.04.009 · 2011 · External reference

Investigating the role of ERAD on antibody processing in glycoengineered Saccharomyces cerevisiae

10.1093/femsyr/foaa002 · 2020 · External reference

Effects of UPR and ERAD pathway on the prolyl endopeptidase production in Pichia pastoris by controlling of nitrogen source

10.1007/s10295-017-1938-8 · 2017 · External reference

COPII-mediated vesicle formation at a glance

10.1242/jcs.069773 · 2011 · External reference

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

10.1371/journal.pbio.2005140 · 2018 · External reference

Structure and organization of coat proteins in the COPII cage

10.1016/j.cell.2007.05.036 · 2007 · External reference

The structure of the COPII transport-vesicle coat assembled on membranes

10.7554/elife.00951 · 2013 · External reference

Insights into COPII coat nucleation from the structure of Sec23•Sar1 complexed with the active fragment of sec31

10.1016/j.devcel.2007.10.006 · 2007 · External reference

Crystal structures of Uso1 membrane tether reveal an alternative conformation in the globular head domain

2020 · External reference

SNAREs, tethers and SM proteins: how to overcome the final barriers to membrane fusion?

10.1042/bcj20190050 · 2020 · External reference

Direct interaction between a Myosin V motor and the rab GTPases Ypt31/32 is required for polarized secretion

10.1091/mbc.e08-02-0220 · 2008 · External reference

Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

10.1038/nsmb.3146 · 2016 · External reference

High-resolution secretory timeline from vesicle formation at the Golgi to fusion at the plasma membrane in S. cerevisiae

10.7554/elife.78750 · 2022 · External reference

Enhance protein secretion pathway and energy metabolism to improved protein activity in recombinant Pichia pastoris

10.1016/j.bej.2025.109935 · 2026 · External reference

Multistep engineering of the secretory pathway for enhanced leghemoglobin expression in Kluyveromyces marxianus

10.1016/j.biortech.2026.134275 · 2026 · External reference

Improved secretory production of glucoamylase in Pichia pastoris by combination of genetic manipulations

10.1016/j.bbrc.2004.11.112 · 2005 · External reference

Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1′ site

2013 · External reference

Coexpression of Kex2 endoproteinase and Hac1 transcription factor to improve the secretory expression of bovine lactoferrin in Pichia pastoris

10.1007/s12257-019-0176-5 · 2019 · External reference

Investigation on the processing and improving the cleavage efficiency of furin cleavage sites in Pichia pastoris

10.1186/s12934-018-1020-x · 2018 · External reference

Modifications in the Kex2 P1′ cleavage site in the α-MAT secretion signal lead to higher production of human granulocyte colony-stimulating factor in Pichia pastoris

10.1007/s11274-021-03167-3 · 2021 · External reference

Identification of a new family of genes involved in β-1,2-mannosylation of glycans in Pichia pastoris and Candida albicans

10.1074/jbc.m708825200 · 2008 · External reference

The impact of O-glycan chemistry on the stability of intrinsically disordered proteins

10.1039/c7sc05016j · 2018 · External reference

Binding of DC-SIGN to glycoproteins expressed in glycoengineered Pichia pastoris

10.1016/j.jim.2012.08.015 · 2012 · External reference

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

10.1038/nprot.2008.213 · 2009 · External reference

Humanization of yeasts for glycan-type end-products

2022 · External reference

Biosynthesis of a functional fragment of Human collagen II in Pichia pastoris

10.1021/acssynbio.4c00345 · 2024 · External reference

Oxidative stress tolerance contributes to heterologous protein production in Pichia pastoris

10.1186/s13068-021-02013-w · 2021 · External reference

N-acetyltransferase co-expression increases a-glucosidase expression level in Pichia pastoris

10.1016/j.jbiotec.2018.11.006 · 2019 · External reference

Differential secretion pathways of proteins fused to the Escherichia coli maltose binding protein (MBP) in Pichia pastoris

10.1016/j.pep.2016.04.005 · 2016 · External reference

Enhancing production and assessing IgE reactivity of dog allergen Can f 6 in Pichia pastoris and Escherichia coli

10.1007/s00253-025-13465-7 · 2025 · External reference

Fusion partner facilitates expression of cell-penetrating peptide L2 in Pichia pastoris

2024 · External reference

High-level expression of Aspergillus niger lipase in Pichia pastoris: characterization and gastric digestion in vitro

10.1016/j.foodchem.2018.09.020 · 2019 · External reference

Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris

10.1007/s00253-023-12606-0 · 2023 · External reference

Fusion expression of cecropin B-like antibacterial peptide in Pichia GS115 and its antibacterial mechanism

10.1007/s10529-015-1978-y · 2016 · External reference

Establishment and application of an RNAi system in Pichia pastoris

10.3389/fbioe.2025.1548187 · 2025 · External reference

Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris

10.1002/biot.201600584 · 2017 · External reference

Disruption of vacuolar protein sorting components of the HOPS complex leads to enhanced secretion of recombinant proteins in Pichia pastoris

10.1186/s12934-019-1155-4 · 2019 · External reference

Yap1-Regulated glutathione redox system curtails accumulation of formaldehyde and reactive oxygen species in methanol metabolism of Pichia pastoris

10.1128/ec.00007-09 · 2009 · External reference

Development of a general defined medium for Pichia pastoris

10.1002/bit.26440 · 2018 · External reference

Metabolic flux analysis for recombinant protein production by Pichia pastoris using dual carbon sources: effects of methanol feeding rate

10.1002/bit.22543 · 2010 · External reference

Medium optimization for enhanced production of recombinant lignin peroxidase in Pichia pastoris

10.1007/s10529-022-03321-3 · 2023 · External reference

Production and purification of soy leghemoglobin from Pichia pastoris cultivated in different expression Media

10.3390/pr11113215 · 2023 · External reference

Expression and characterization of the antimicrobial peptide ABP-dHC-cecropin A in the methylotrophic yeast Pichia pastoris

10.1016/j.pep.2017.08.001 · 2017 · External reference

An engineered Pichia pastoris platform for the biosynthesis of silk-based nanomaterials with therapeutic potential

10.1016/j.ijbiomac.2024.131954 · 2024 · External reference

Microbial astaxanthin synthesis by Komagataella phaffii through Metabolic and Fermentation engineering

10.1021/acs.jafc.4c10113 · 2025 · External reference

Biocalorimetric monitoring of glycoengineered P. pastoris cultivation for the production of recombinant huIFNα2b: a quantitative study based on mixed feeding strategies

10.1002/btpr.2971 · 2020 · External reference

Development of a dual specific growth rate-based fed-batch process for production of recombinant human granulocyte colony-stimulating factor inPichia pastoris

10.1007/s00449-020-02427-0 · 2021 · External reference

Enhanced human lysozyme production by Pichia pastoris via periodic glycerol and dissolved oxygen concentrations control

10.1007/s00253-021-11100-9 · 2021 · External reference

Controlling specific growth rate for recombinant protein production by Pichia pastoris under oxidation stress in fed-batch fermentation

10.1007/s12010-022-04022-3 · 2022 · External reference

Accuracy and data efficiency in deep learning models of protein expression

10.1038/s41467-022-34902-5 · 2022 · External reference

Presep: predicting the propensity of a protein being secreted into the supernatant when expressed in Pichia pastoris

10.1371/journal.pone.0079749 · 2013 · External reference

Effective gene expression prediction and optimization from protein sequences

2025 · External reference

Accurate design of translational output by a neural network model of ribosome distribution

10.1038/s41594-018-0080-2 · 2018 · External reference

AggreProt: a web server for predicting and engineering aggregation prone regions in proteins

10.1093/nar/gkae420 · 2024 · External reference

Accurate and cost-effective prediction of HBsAg titer in industrial scale fermentation process of recombinant Pichia pastoris by using neural network based soft sensor

10.1002/bab.1785 · 2019 · External reference

Deployment of metabolic heat rate based soft sensor for estimation and control of specific growth rate in glycoengineered Pichia pastoris for human interferon alpha 2b production

10.1016/j.jbiotec.2022.10.006 · 2022 · External reference

Soft sensor modeling method for pichia pastoris fermentation process based on domain adaptation ensemble LSTM

10.1016/j.aej.2025.05.078 · 2025 · External reference

A robust feeding control strategy adjusted and optimized by a neural network for enhancing of alpha 1-antitrypsin production in Pichia pastoris

10.1016/j.bej.2019.01.005 · 2019 · External reference

Modeling and optimization of recombinant Tocilizumab production from Pichia pastoris using response surface methodology and artificial neural network

10.1002/bit.29024 · 2025 · External reference

Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast pichia pastoris for strain improvement

10.1186/1475-2859-9-50 · 2010 · External reference

Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production

10.1002/biot.201000078 · 2010 · External reference

Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials

10.1186/1752-0509-6-24 · 2012 · External reference

Integration and validation of the genome-scale metabolic models of Pichia pastoris: a comprehensive update of protein glycosylation pathways, lipid and energy metabolism

10.1371/journal.pone.0148031 · 2016 · External reference

Genome-scale metabolic model analysis of Pichia pastoris for enhancing the production of S-adenosyl-L-methionine

10.1007/s00449-023-02913-1 · 2023 · External reference

Modeling meets metabolic engineering: the iPichia consensus model as basis for metabolic studies in Komagataella phaffii

10.1016/j.bej.2025.109940 · 2026 · External reference

A versatile toolbox for CRISPR-based genome engineering in Pichia pastoris

10.1007/s00253-021-11688-y · 2021 · External reference

Screening and characterization of integration sites based on CRISPR-Cpf1 in Pichia pastoris

10.1016/j.synbio.2024.06.002 · 2024 · External reference

Synthetic biology toolkit for marker-less integration of multigene pathways into Pichia pastoris via CRISPR/Cas9

10.1021/acssynbio.1c00307 · 2022 · External reference

Systematic Engineering of Komagataella phaffii for efficient kestose biosynthesis: integrating expression optimization with Secretory pathway engineering

10.1021/acs.jafc.6c02107 · 2026 · External reference

10.1016/j.csbj.2022.02.030 · 2022 · Admitted local publication

Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli

10.1038/nbt.4238 · 2018 · External reference

Efficient secretory expression of type III recombinant human collagen with triple-helical structure in Komagataella phaffii

10.1007/s00253-025-13566-3 · 2025 · External reference