Research graph
References from Association between prenatal trace element and toxic metal exposures and autism spectrum disorder symptoms in children: Potential mediating role of cord serum metabolites. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2025 · External reference
An exposome connectivity paradigm for the mechanistic assessment of the effects of prenatal and early life exposure to metals on neurodevelopment
2022 · External reference
Monoamines: dopamine, norepinephrine, and serotonin, beyond modulation, "switches" that alter the state of target networks
10.1177/1073858420974336 · 2022 · External reference
Metal profiles in autism spectrum disorders: a crosstalk between toxic and essential metals
10.3390/ijms24010308 · 2022 · External reference
Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals
10.1186/s13148-021-01198-z · 2021 · External reference
Prenatal exposure to metals and autism spectrum disorder: current status and future directions
10.1016/j.cotox.2021.04.001 · 2021 · External reference
Neurodevelopmental effects of maternal folic acid supplementation: a systematic review and meta-analysis
10.1080/10408398.2021.1993781 · 2023 · External reference
Relationship between pregnant women's combined exposure to heavy metals and their offspring's congenital heart defects in Lanzhou, China
2024 · External reference
Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs)
10.1093/exposome/osae001 · 2024 · External reference
Cord blood manganese concentrations in relation to birth outcomes and childhood physical growth: a prospective birth cohort study
10.3390/nu13124304 · 2021 · External reference
Autism spectrum disorder, social anxiety and obsessive-compulsive disorders: beyond the comorbidity
10.1186/s12888-024-06340-8 · 2025 · External reference
Antenatal nutritional supplementation and autism spectrum disorders in the Stockholm youth cohort: population based cohort study
2017 · External reference
Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis
10.3389/fped.2023.1169733 · 2023 · External reference
Exposure to heavy metals in utero and autism spectrum disorder at age 3: a meta-analysis of two longitudinal cohorts of siblings of children with autism
10.1186/s12940-024-01101-2 · 2024 · External reference
Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder
10.1038/s41398-020-00905-3 · 2020 · External reference
Ketone bodies in the brain beyond fuel metabolism: from excitability to gene expression and cell signaling
10.3389/fnmol.2021.732120 · 2021 · External reference
Prenatal mercury exposure and features of autism: a prospective population study
10.1186/s13229-018-0215-7 · 2018 · External reference
Persistence of autism spectrum disorder from early childhood through school age
10.1001/jamapediatrics.2023.4003 · 2023 · External reference
Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu birth cohort for mothers and children (HBC study)
10.1111/pcn.13710 · 2024 · External reference
Cohort profile: the Ma'anshan birth cohort (MABC) study
10.1093/ije/dyae142 · 2024 · External reference
The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities
10.1089/ars.2011.4145 · 2012 · External reference
Dopaminergic perturbation in the aetiology of neurodevelopmental disorders
10.1007/s12035-024-04418-8 · 2025 · External reference
A general approach to causal mediation analysis
10.1037/a0020761 · 2010 · External reference
Prenatal maternal stress, breastfeeding and offspring ADHD symptoms
10.1007/s00787-024-02451-5 · 2024 · External reference
Prenatal exposure to a wide range of environmental chemicals and child behaviour between 3 and 7 years of age - an exposome-based approach in 5 European cohorts
10.1016/j.scitotenv.2020.144115 · 2021 · External reference
Epidemiological investigation on autism spectrum disorders among preschool children in Shanghai
2015 · External reference
Prevalence of autism spectrum disorder in mainland China over the past 6 years: a systematic review and meta-analysis
10.1186/s12888-024-05729-9 · 2024 · External reference
A quantile-based g-computation approach to addressing the effects of exposure mixtures
10.1289/ehp5838 · 2020 · External reference
Impact of prenatal exposure to mercury and selenium on neurodevelopmental delay in children in the Japan environment and Children's study using the ASQ-3 questionnaire: a prospective birth cohort
10.1016/j.envint.2022.107448 · 2022 · External reference
Comparison of the clancy autism behavior scale and autism behavior checklist for screening autism spectrum disorder
2023 · External reference
The copper-zinc superoxide dismutase activity in selected diseases
10.1111/eci.13036 · 2019 · External reference
Determine multiple elements simultaneously in the sera of umbilical cord blood Samples-a very simple method
10.1007/s12011-016-0853-6 · 2017 · External reference
Trace element profiles in pregnant women's sera and umbilical cord sera and influencing factors: repeated measurements
10.1016/j.chemosphere.2018.11.115 · 2019 · External reference
Associations of prenatal metal exposures with autism-related outcomes in the ECHO cohort
10.1097/ee9.0000000000000500 · 2026 · External reference
Parental major life events before or during pregnancy and autistic behaviors among preschool children
2025 · External reference
Prenatal OPEs Trimester- and sex-specifically linked to trajectories of preschoolers' emotional and behavioral problems: insights from cord blood metabolomics
10.1021/acs.est.5c08732 · 2025 · External reference
Autism spectrum disorder
10.1038/s41572-019-0138-4 · 2020 · External reference
How does multiple testing correction work?
10.1038/nbt1209-1135 · 2009 · External reference
The plausibility of maternal toxicant exposure and nutritional status as contributing factors to the risk of autism spectrum disorders
10.1080/1028415x.2015.1103437 · 2017 · External reference
Missing data imputation method combining random forest and generative adversarial imputation network
10.3390/s24041112 · 2024 · External reference
Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses' health study II participants
10.1289/ehp.1206187 · 2013 · External reference
Maternal intake of supplemental iron and risk of autism spectrum disorder
10.1093/aje/kwu208 · 2014 · External reference
Prenatal exposure to mixtures of heavy metals and neurodevelopment in infants at 6 months
10.1016/j.envres.2020.109122 · 2020 · External reference
Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 years - autism and developmental disabilities monitoring network, 16 sites, United States, 2022
10.15585/mmwr.ss7402a1 · 2025 · External reference
Metal and essential element concentrations during pregnancy and associations with autism spectrum disorder and attention-deficit/hyperactivity disorder in children
10.1016/j.envint.2021.106468 · 2021 · External reference
Prenatal exposure to metal mixtures and newborn neurobehavior in the Rhode Island child health study
10.1097/ee9.0000000000000194 · 2022 · External reference
Ketosis elevates antioxidants and enhances neural function through improved bioenergetics: a 1HMR spectroscopy study
2024 · External reference
Sex- and trimester-specific associations of prenatal Co-Exposure to organophosphate esters and phthalates with preschoolers' trajectories of Co-Occurring ADHD and ASD symptoms: Cord blood metabolomic study in the Ma'anshan birth cohort
10.1021/acs.est.6c01402 · 2026 · External reference
Selenium in thyroid disorders - essential knowledge for clinicians
10.1038/s41574-019-0311-6 · 2020 · External reference
Associations of prenatal metal exposure with child neurodevelopment and mediation by perturbation of metabolic pathways
10.1038/s41467-025-57253-3 · 2025 · External reference
Prenatal and neonatal peripheral blood mercury levels and autism spectrum disorders
10.1016/j.envres.2014.04.034 · 2014 · External reference
Joint trajectories of ADHD and autistic traits in preschoolers linked to prenatal phthalate exposure: insights from the cord blood metabolome
10.1016/j.envint.2026.110402 · 2026 · External reference
Risk of neurodevelopmental disorders in preschool children associated with the longitudinal trajectory of phthalates during pregnancy: potential mechanisms based on metabonomics of cord blood
10.1021/acs.est.5c00115 · 2025 · External reference
Global prevalence of autism: a systematic review update
10.1002/aur.2696 · 2022 · External reference
A metabolome-wide association study of in utero metal and trace element exposures with cord blood metabolome profile: findings from the Boston birth cohort
10.1016/j.envint.2021.106976 · 2022 · External reference
Genetic evidence of gender difference in autism spectrum disorder supports the female-protective effect
10.1038/s41398-020-0699-8 · 2020 · External reference
Persistence of autism spectrum disorder from early childhood through school age
10.1001/jamapediatrics.2023.4003 · ExternalCitation · doi-reference
Global prevalence of autism: a systematic review update
10.1002/aur.2696 · ExternalCitation · doi-reference
Prenatal maternal stress, breastfeeding and offspring ADHD symptoms
10.1007/s00787-024-02451-5 · ExternalCitation · doi-reference
Determine multiple elements simultaneously in the sera of umbilical cord blood Samples-a very simple method
10.1007/s12011-016-0853-6 · ExternalCitation · doi-reference
Dopaminergic perturbation in the aetiology of neurodevelopmental disorders
10.1007/s12035-024-04418-8 · ExternalCitation · doi-reference
Trace element profiles in pregnant women's sera and umbilical cord sera and influencing factors: repeated measurements
10.1016/j.chemosphere.2018.11.115 · ExternalCitation · doi-reference
Prenatal exposure to metals and autism spectrum disorder: current status and future directions
10.1016/j.cotox.2021.04.001 · ExternalCitation · doi-reference
Metal and essential element concentrations during pregnancy and associations with autism spectrum disorder and attention-deficit/hyperactivity disorder in children
10.1016/j.envint.2021.106468 · ExternalCitation · doi-reference
A metabolome-wide association study of in utero metal and trace element exposures with cord blood metabolome profile: findings from the Boston birth cohort
10.1016/j.envint.2021.106976 · ExternalCitation · doi-reference
Impact of prenatal exposure to mercury and selenium on neurodevelopmental delay in children in the Japan environment and Children's study using the ASQ-3 questionnaire: a prospective birth cohort
10.1016/j.envint.2022.107448 · ExternalCitation · doi-reference
Joint trajectories of ADHD and autistic traits in preschoolers linked to prenatal phthalate exposure: insights from the cord blood metabolome
10.1016/j.envint.2026.110402 · ExternalCitation · doi-reference
Prenatal and neonatal peripheral blood mercury levels and autism spectrum disorders
10.1016/j.envres.2014.04.034 · ExternalCitation · doi-reference
Prenatal exposure to mixtures of heavy metals and neurodevelopment in infants at 6 months
10.1016/j.envres.2020.109122 · ExternalCitation · doi-reference
Prenatal exposure to a wide range of environmental chemicals and child behaviour between 3 and 7 years of age - an exposome-based approach in 5 European cohorts
10.1016/j.scitotenv.2020.144115 · ExternalCitation · doi-reference
Risk of neurodevelopmental disorders in preschool children associated with the longitudinal trajectory of phthalates during pregnancy: potential mechanisms based on metabonomics of cord blood
10.1021/acs.est.5c00115 · ExternalCitation · doi-reference
Prenatal OPEs Trimester- and sex-specifically linked to trajectories of preschoolers' emotional and behavioral problems: insights from cord blood metabolomics
10.1021/acs.est.5c08732 · ExternalCitation · doi-reference
Sex- and trimester-specific associations of prenatal Co-Exposure to organophosphate esters and phthalates with preschoolers' trajectories of Co-Occurring ADHD and ASD symptoms: Cord blood metabolomic study in the Ma'anshan birth cohort
10.1021/acs.est.6c01402 · ExternalCitation · doi-reference
A general approach to causal mediation analysis
10.1037/a0020761 · ExternalCitation · doi-reference
How does multiple testing correction work?
10.1038/nbt1209-1135 · ExternalCitation · doi-reference
Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder
10.1038/s41398-020-00905-3 · ExternalCitation · doi-reference
Genetic evidence of gender difference in autism spectrum disorder supports the female-protective effect
10.1038/s41398-020-0699-8 · ExternalCitation · doi-reference
Associations of prenatal metal exposure with child neurodevelopment and mediation by perturbation of metabolic pathways
10.1038/s41467-025-57253-3 · ExternalCitation · doi-reference
Autism spectrum disorder
10.1038/s41572-019-0138-4 · ExternalCitation · doi-reference
Selenium in thyroid disorders - essential knowledge for clinicians
10.1038/s41574-019-0311-6 · ExternalCitation · doi-reference
The plausibility of maternal toxicant exposure and nutritional status as contributing factors to the risk of autism spectrum disorders
10.1080/1028415x.2015.1103437 · ExternalCitation · doi-reference
Neurodevelopmental effects of maternal folic acid supplementation: a systematic review and meta-analysis
10.1080/10408398.2021.1993781 · ExternalCitation · doi-reference
The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities
10.1089/ars.2011.4145 · ExternalCitation · doi-reference
Maternal intake of supplemental iron and risk of autism spectrum disorder
10.1093/aje/kwu208 · ExternalCitation · doi-reference
Decoding the exposome: data science methodologies and implications in exposome-wide association studies (ExWASs)
10.1093/exposome/osae001 · ExternalCitation · doi-reference
Cohort profile: the Ma'anshan birth cohort (MABC) study
10.1093/ije/dyae142 · ExternalCitation · doi-reference
Prenatal exposure to metal mixtures and newborn neurobehavior in the Rhode Island child health study
10.1097/ee9.0000000000000194 · ExternalCitation · doi-reference
Associations of prenatal metal exposures with autism-related outcomes in the ECHO cohort
10.1097/ee9.0000000000000500 · ExternalCitation · doi-reference
The copper-zinc superoxide dismutase activity in selected diseases
10.1111/eci.13036 · ExternalCitation · doi-reference
Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu birth cohort for mothers and children (HBC study)
10.1111/pcn.13710 · ExternalCitation · doi-reference
Monoamines: dopamine, norepinephrine, and serotonin, beyond modulation, "switches" that alter the state of target networks
10.1177/1073858420974336 · ExternalCitation · doi-reference
Prevalence of autism spectrum disorder in mainland China over the past 6 years: a systematic review and meta-analysis
10.1186/s12888-024-05729-9 · ExternalCitation · doi-reference
Autism spectrum disorder, social anxiety and obsessive-compulsive disorders: beyond the comorbidity
10.1186/s12888-024-06340-8 · ExternalCitation · doi-reference
Exposure to heavy metals in utero and autism spectrum disorder at age 3: a meta-analysis of two longitudinal cohorts of siblings of children with autism
10.1186/s12940-024-01101-2 · ExternalCitation · doi-reference
Prenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals
10.1186/s13148-021-01198-z · ExternalCitation · doi-reference
Prenatal mercury exposure and features of autism: a prospective population study
10.1186/s13229-018-0215-7 · ExternalCitation · doi-reference
Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses' health study II participants
10.1289/ehp.1206187 · ExternalCitation · doi-reference
A quantile-based g-computation approach to addressing the effects of exposure mixtures
10.1289/ehp5838 · ExternalCitation · doi-reference
Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 years - autism and developmental disabilities monitoring network, 16 sites, United States, 2022
10.15585/mmwr.ss7402a1 · ExternalCitation · doi-reference
Ketone bodies in the brain beyond fuel metabolism: from excitability to gene expression and cell signaling
10.3389/fnmol.2021.732120 · ExternalCitation · doi-reference
Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis
10.3389/fped.2023.1169733 · ExternalCitation · doi-reference
Metal profiles in autism spectrum disorders: a crosstalk between toxic and essential metals
10.3390/ijms24010308 · ExternalCitation · doi-reference
Cord blood manganese concentrations in relation to birth outcomes and childhood physical growth: a prospective birth cohort study
10.3390/nu13124304 · ExternalCitation · doi-reference
Missing data imputation method combining random forest and generative adversarial imputation network
10.3390/s24041112 · ExternalCitation · doi-reference
