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References from Cardiac injury and purine metabolic remodeling in Carassius auratus under environmentally relevant carbonate alkalinity exposure. Local targets link to admitted publications; unresolved targets remain external evidence.
Diatom community response to inland water salinization: a review
10.1007/s10750-023-05167-w · 2023 · External reference
A review of the defining chemical properties of soda lakes and pans: An assessment on a large geographic scale of Eurasian inland saline surface waters
10.1371/journal.pone.0202205 · 2018 · External reference
Assessment of saline-alkaline water quality and rice-crab co-culture improvement effects in the Songnen Plain
10.1038/s41598-026-37967-0 · 2026 · External reference
Effects of Different Saline-Alkaline Conditions on the Characteristics of Phytoplankton Communities in the Lakes of Songnen Plain, China
10.1371/journal.pone.0164734 · 2016 · External reference
Carbonic anhydrase 2-like and Na+-K+-ATPase α gene expression in medaka (Oryzias latipes) under carbonate alkalinity stress
10.1007/s10695-015-0101-6 · 2015 · External reference
Lysine deacetylase inhibitors (KDACi) enhance the adaptability of tilapia (Oreochromis niloticus) to carbonate alkalinity stress
10.1016/j.aquaculture.2025.742492 · 2025 · External reference
Variation in pH, HCO3−, carbonic anhydrases, and HCO3− transporters in Nile tilapia during carbonate alkalinity stress
10.1007/s10750-022-05020-6 · 2023 · External reference
Study on the physiological responses and tolerance mechanisms to subchronic carbonate alkalinity exposure in the gills of Paramisgurnus dabryanus
10.1016/j.ecoenv.2024.117319 · 2024 · External reference
Effects of Saline-Alkaline Stress on Metabolome, Biochemical Parameters, and Histopathology in the Kidney of Crucian Carp (Carassius auratus)
10.3390/metabo13020159 · 2023 · External reference
Stress response and tolerance mechanisms of NaHCO3 exposure based on biochemical assays and multi-omics approach in the liver of crucian carp (Carassius auratus)
10.1016/j.ecoenv.2023.114633 · 2023 · External reference
Metabolism responses in the intestine of Oreochromis mossambicus exposed to salinity, alkalinity and salt-alkalinity stress using LC-MS/MS-based metabolomics
2023 · External reference
Ammonia nitrogen accumulation and metabolic regulation in large-scale loach (Paramisgurnus dabryanus) exposed to sub-chronic carbonate alkalinity: Insights from biochemical and omics analyses
10.1016/j.aquaculture.2025.743426 · 2026 · External reference
Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling
10.1016/s0301-0082(00)00043-5 · 2001 · External reference
Cardiac Hypoxia Tolerance in Fish: From Functional Responses to Cell Signals
10.3390/ijms24021460 · 2023 · External reference
Effects of environmental hypoxia on cardiac energy metabolism and performance in tilapia
10.1152/ajpregu.00418.2009 · 2010 · External reference
10.1002/cphy.c230011
10.1002/cphy.c230011 · External reference
AMPK: a nutrient and energy sensor that maintains energy homeostasis
10.1038/nrm3311 · 2012 · External reference
The purine nucleotide cycle as two temporally separated metabolic units: A study on trout muscle
10.1016/0026-0495(88)90170-9 · 1988 · External reference
Structure and function of xanthine oxidoreductase: where are we now?
10.1016/s0891-5849(02)00956-5 · 2002 · External reference
Ammonia accumulation triggers hepatic metabolic dysregulation and oxidative damage in grass carp (Ctenopharyngodon idellus) exposed to carbonate alkalinity: A metabolomic insight
2026 · External reference
Mechanisms by which α-ketoglutarate alleviates intestinal injury caused by carbonate-alkaline stress in crucian carp (Carassius auratus): Insights from metabolomics and microbiomics
2026 · External reference
Growth performance, antioxidant capacity, intestinal microbiota, and metabolomics analysis of Nile tilapia (Oreochromis niloticus) under carbonate alkalinity stress
10.1016/j.aquaculture.2024.741675 · 2025 · External reference
Exploring Disparities in Gill Physiological Responses to NaHCO3-Induced Habitat Stress in Triploid and Diploid Crucian Carp (Carassius auratus): A Comprehensive Investigation Through Multi-Omics and Biochemical Analyses
10.3390/metabo15010005 · 2024 · External reference
Integrated application of multi-omics approach and biochemical assays provides insights into physiological responses to saline-alkaline stress in the gills of crucian carp (Carassius auratus)
10.1016/j.scitotenv.2022.153622 · 2022 · External reference
Cardiac Energy Metabolism in Heart Failure
10.1161/circresaha.121.318241 · 2021 · External reference
The assembly, regulation and function of the mitochondrial respiratory chain
10.1038/s41580-021-00415-0 · 2022 · External reference
Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
10.1016/j.cell.2013.08.032 · 2013 · External reference
Maintained mitochondrial integrity without oxygen in the anoxia-tolerant crucian carp
10.1242/jeb.247409 · 2024 · External reference
The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste
10.1152/physrev.00050.2003 · 2005 · External reference
Ammonia production, excretion, toxicity, and defense in fish: a review
10.3389/fphys.2010.00134 · 2010 · External reference
Ammonia excretion and urea handling by fish gills: present understanding and future research challenges
10.1002/jez.10123 · 2002 · External reference
Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence
10.1172/jci.insight.154089 · 2021 · External reference
Ammonia-induced mitochondrial dysfunction and energy metabolism disturbances in isolated brain and liver mitochondria, and the effect of taurine administration: relevance to hepatic encephalopathy treatment
10.5114/ceh.2017.68833 · 2017 · External reference
Effects of prolonged NaHCO3 exposure on the serum immune function, antioxidant capacity, intestinal tight junctions, microbiota, mitochondria, and autophagy in crucian carp (Carassius auratus)
10.1016/j.ecoenv.2024.117571 · 2025 · External reference
AMP-activated protein kinase: nature’s energy sensor
10.1038/nchembio.610 · 2011 · External reference
Interplay between adenylate metabolizing enzymes and AMP‐activated protein kinase
10.1111/febs.14508 · 2018 · External reference
Inosine and hypoxanthine as novel biomarkers for cardiac ischemia: From bench to point-of-care
10.1177/1535370215584931 · 2015 · External reference
The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors
2021 · External reference
Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion
10.1073/pnas.97.20.10723 · 2000 · External reference
Mammalian xanthine oxidoreductase – mechanism of transition from xanthine dehydrogenase to xanthine oxidase
10.1111/j.1742-4658.2008.06489.x · 2008 · External reference
The Reaction of Reduced Xanthine Dehydrogenase with Molecular Oxygen
10.1074/jbc.272.13.8370 · 1997 · External reference
Hydrogen peroxide is the major oxidant product of xanthine oxidase
10.1016/j.freeradbiomed.2009.11.012 · 2010 · External reference
Modification of the xanthine-converting enzyme of perfused rat heart during ischemia and oxidative stress
10.1016/0891-5849(88)90024-x · 1988 · External reference