Research graph
References from Biomarker discovery and diagnostic modeling in diabetic retinopathy: A bioinformatics analysis targeting inflammatory-angiogenic pathways. Local targets link to admitted publications; unresolved targets remain external evidence.
The molecular basis of human retinal and vitreoretinal diseases
10.1016/j.preteyeres.2010.03.004 · 2010 · External reference
Metabolic pathways of the warburg effect in health and disease: perspectives of choice, chain or chance
10.3390/ijms18122755 · 2017 · External reference
Unresolved reference
2000 · External reference
An angiogenesis-associated gene-based signature predicting prognosis and immunotherapy efficacy of head and neck squamous cell carcinoma patients
10.1007/s00432-024-05606-8 · 2024 · External reference
Association of THBS1 genetic variants and mRNA expression with the risks of ischemic stroke and long-term death after stroke
10.3389/fnagi.2022.1006473 · 2022 · External reference
New gene targets for diagnosis and therapy of diabetic retinopathy
10.5152/eurasianjmed.2025.24559 · 2025 · External reference
GEOquery: a bridge between the gene expression omnibus (GEO) and BioConductor
2007 · External reference
Vitreous expression of cytokines and growth factors in patients with diabetic retinopathy-An investigation of their expression based on clinical diabetic retinopathy grade
10.1371/journal.pone.0248439 · 2021 · External reference
Statistical predictions with glmnet
10.1186/s13148-019-0730-1 · 2019 · External reference
Predicting molecular mechanisms, pathways, and health outcomes induced by Juul e-cigarette aerosol chemicals using the comparative toxicogenomics database
10.1016/j.crtox.2021.08.001 · 2021 · External reference
Comprehensive analysis of angiogenesis-related genes and pathways in early diabetic retinopathy
10.1186/s12920-020-00799-6 · 2020 · External reference
Evaluation of microaneurysms as predictors of therapeutic response to anti-VEGF therapy in patients with DME
10.1371/journal.pone.0277920 · 2022 · External reference
Construction and validation of a prognostic model of angiogenesis-related genes in multiple myeloma
10.1186/s12885-024-13024-9 · 2024 · External reference
Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy
10.1167/iovs.14-15589 · 2015 · External reference
Endothelium expression of Bcl-2 is essential for normal and pathological ocular vascularization
2015 · External reference
Identification of a new gene signature for prognostic evaluation in cervical cancer: based on cuproptosis-associated angiogenesis and multi-omics analysis
10.1186/s12935-023-03189-x · 2024 · External reference
Inflammatory and angiogenic biomarkers in diabetic retinopathy
10.11613/bm.2020.030502 · 2020 · External reference
The pathology associated with diabetic retinopathy
10.1016/j.visres.2017.04.003 · 2017 · External reference
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-seq data
10.1093/nar/gkt1248 · 2014 · External reference
Comprehensive analysis of angiogenesis associated genes and tumor microenvironment infiltration characterization in cervical cancer
2024 · External reference
THBS1 in macrophage-derived exosomes exacerbates cerebral ischemia-reperfusion injury by inducing ferroptosis in endothelial cells
10.1186/s12974-025-03382-x · 2025 · External reference
Identification and verification of inflammatory biomarkers for primary Sjögren's syndrome
10.1007/s10067-024-06901-y · 2024 · External reference
Identification of unique biomarkers for proliferative diabetic retinopathy with tractional retinal detachment by proteomics profiling of vitreous humor
2025 · External reference
Secreted protein acidic and rich in cysteine mediates the development and progression of diabetic retinopathy
10.3389/fendo.2022.869519 · 2022 · External reference
Silencing of miR-20b-5p exerts inhibitory effect on diabetic retinopathy via inactivation of THBS1 gene induced VEGF/Akt/PI3K pathway
10.2147/dmso.s299143 · 2021 · External reference
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
10.1093/nar/gky1038 · 2019 · External reference
An ocular view of the IGF-IGFBP system
10.1016/j.ghir.2013.03.001 · 2013 · External reference
PAI-1 is a vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal neovascularization in diabetic patients
10.1126/sciadv.abm1896 · 2022 · External reference
Limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
pROC: an open-source package for R and S+ to analyze and compare ROC curves
10.1186/1471-2105-12-77 · 2011 · External reference
SVM-RFE: selection and visualization of the most relevant features through non-linear kernels
10.1186/s12859-018-2451-4 · 2018 · External reference
The GeneCards suite: from gene data mining to disease genome sequence analyses
10.1002/cpbi.5 · 2016 · External reference
IDF diabetes atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045
10.1016/j.diabres.2021.109119 · 2022 · External reference
Reporting and interpreting decision curve analysis: a guide for investigators
10.1016/j.eururo.2018.08.038 · 2018 · External reference
DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions
10.1093/nar/gku1215 · 2015 · External reference
The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy
10.1038/s41392-025-02176-0 · 2025 · External reference
Application of an angiogenesis-related genes risk model in lung adenocarcinoma prognosis and immunotherapy
2023 · External reference
High glucose treatment induces nuclei aggregation of microvascular endothelial cells via the foxo1a- klf2a pathway
10.1161/atvbaha.124.321719 · 2025 · External reference
GOSemSim: an R package for measuring semantic similarity among GO terms and gene products
10.1093/bioinformatics/btq064 · 2010 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway
10.4081/ejh.2022.3522 · 2022 · External reference
Identification of biomarkers related to angiogenesis in myocardial ischemia-reperfusion injury and prediction of potential drugs
2024 · External reference
High glucose aggravates retinal endothelial cell dysfunction by activating the RhoA/ROCK1/pMLC/Connexin43 signaling pathway
2022 · External reference
Constructing models for Crohn's disease diagnosis and prediction of infliximab non-response based on angiogenesis-related genes
2024 · External reference
Immunological characterization of stroke-heart syndrome and identification of inflammatory therapeutic targets
10.3389/fimmu.2023.1227104 · 2023 · External reference