Research graph
References from Biomarkers of experimental Toxocara canis infection are context-dependent: A systematic review of murine models. Local targets link to admitted publications; unresolved targets remain external evidence.
Histopathological changes, dynamics of macrophage polarization and deposition of type I and III collagen along the course of experimental hepatic toxocariasis
10.1016/j.exppara.2025.109082 · 2026 · External reference
Neurobehavioral disorders and pathological changes in the brain of mice are caused by chronic Toxocara canis larval invasion with low to moderate inoculum
10.1007/s11686-024-00869-0 · 2024 · External reference
Toxocara canis infections in mice: from subtle to severe consequences in 100 weeks
2025 · External reference
Acute and chronic immunomodulatory response mechanisms against Toxocara canis larvae infection in mice
10.1590/s1984-29612022056 · 2022 · External reference
Toxocara canis-induced murine pulmonary inflammation: analysis of cells and proteins in lung tissue and bronchoalveolar lavage fluid
10.1111/j.1365-3024.1994.tb00297.x · 1994 · External reference
Renal involvement in mice experimentally infected with Toxocara canis embryonated eggs
10.1016/0304-4017(92)90068-k · 1992 · External reference
Toxocariasis: a silent threat with a progressive public health impact
10.1186/s40249-018-0437-0 · 2018 · External reference
10.1590/s0036-46651995000300001
10.1590/s0036-46651995000300001 · External reference
Enhanced neurodegeneration-associated factors in mice infected with Toxocara canis
10.1186/s13071-017-2578-6 · 2017 · External reference
Dynamics of ex vivo cytokine transcription during experimental Toxocara canis infection in Balb/c mice
2024 · External reference
Immunomodulative effect of muramyldipeptide in mice with larval toxocarosis
10.1007/s004360050678 · 1999 · External reference
Immunopathological changes in the brain of immunosuppressed mice experimentally infected with Toxocara canis
10.3347/kjp.2015.53.1.51 · 2015 · External reference
Evaluation of a di-O-methylated glycan as a potential antigenic target for serodiagnosis of human toxocariasis
10.1111/pim.12311 · 2016 · External reference
The behavior and pathogenicity of Toxacara canis larvae in mice of different strains
10.1007/bf00932955 · 1994 · External reference
Infectivity and pathogenicity of 14-month-cultured embryonated eggs of Toxocara canis in mice
10.1016/s0304-4017(03)00046-3 · 2003 · External reference
Enhanced expression of transforming growth factor-β1 in inflammatory cells and secretory granules in Paneth cells in the small intestine of mice infected with Toxocara canis
10.1007/s00436-004-1233-2 · 2004 · External reference
Enhanced inducible nitric oxide synthase expression and nitrotyrosine accumulation in experimental granulomatous hepatitis caused by Toxocara canis in mice
10.1111/j.0141-9838.2004.00708.x · 2004 · External reference
Relationship between parasitical inoculum and immunological parameters in experimental toxocariasis
10.1016/s0934-8840(11)80720-6 · 1995 · External reference
A dual role for macrophages during Toxocara canis infection
10.3390/pathogens8040280 · 2019 · External reference
Experimental ocular toxocariasis: a mouse model
10.1136/bjo.68.2.89 · 1984 · External reference
Cytokine expression in the brains of Toxocara canis-infected mice
10.1111/j.1365-3024.2007.01002.x · 2008 · External reference
Evidence for asthma in the lungs of mice inoculated with different doses of Toxocara canis
10.4269/ajtmh.20-0484 · 2020 · External reference
Neurotoxocarosis alters myelin protein gene transcription and expression
10.1007/s00436-015-4407-1 · 2015 · External reference
Effects of Toxocara canis infection on hemopoietic stem cells and hemopoietic factors in mice
1990 · External reference
SYRCLE’s risk of bias tool for animal studies
10.1186/1471-2288-14-43 · 2014 · External reference
Neurotoxocarosis: marked preference of Toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse
10.1186/1756-3305-7-194 · 2014 · External reference
Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes
10.1016/j.ijpara.2015.02.009 · 2015 · External reference
Abnormal neurobehaviour and impaired memory function as a consequence of Toxocara canis- as well as Toxocara cati-induced neurotoxocarosis
10.1371/journal.pntd.0005594 · 2017 · External reference
Toxocara canis: failure to find IgE receptors (FcεR) on eosinophils from infected mice suggests that murine eosinophils do not kill helminth larvae by an IgE-dependent mechanism
10.1006/expr.1994.1006 · 1994 · External reference
Analysis of seroreactivity and seropositivity in BALB/c mice experimentally infected with Toxocara canis using two recombinant (rTc-CTL-1 and rTES-120) antigens
10.1007/s11686-024-00940-w · 2025 · External reference
Toxocara canis: T lymphocyte function in murine visceral larva migrans and eosinophilia onset
10.1016/0014-4894(80)90055-7 · 1980 · External reference
Immune responses of CBA/J mice to graded infections with Toxocara canis
10.1128/iai.48.3.697-703.1985 · 1985 · External reference
Nonspecific allergic granulomatosis in the lungs of mice infected with large but not small inocula of the canine ascarid, Toxocara canis
10.1016/0090-1229(86)90051-6 · 1986 · External reference
Organ-specific Toxocara canis larvae migration and host immune response in experimentally infected mice. Parasites
10.3347/phd.23125 · 2024 · External reference
Mechanisms of eosinophilia in BALB/c-nu/+ and congenitally athymic BALB/c-nu/nu mice infected with Toxocara canis
1995 · External reference
COX-2/PGE2 signaling drives Toxocara canis-induced lung pathology by enhancing plasminogen activator activity and collagen VI degradation
10.1038/s41598-025-22711-x · 2025 · External reference
Detrimental role of IL-33/ST2 pathway sustaining a chronic eosinophil-dependent Th2 inflammatory response, tissue damage and parasite burden during Toxocara canis infection in mice
10.1371/journal.pntd.0009639 · 2021 · External reference
IL-17RA receptor signaling contributes to lung inflammation and parasite burden during Toxocara canis infection in mice
10.3389/fimmu.2022.864632 · 2022 · External reference
Tissue eosinophilia correlates with mice susceptibility, granuloma formation and damage during Toxocara canis infection
10.1017/s0031182022000075 · 2022 · External reference
Characteristics of Toxocara canis induced lung inflammation in C57BL/6 mice
10.3389/fimmu.2025.1597778 · 2025 · External reference
IgG antibody responses in mice coinfected with Toxocara canis and other helminths or protozoan parasites
10.1590/s0036-46652012000300006 · 2012 · External reference
Matrix metalloproteinases activation in Toxocara canis-induced pulmonary pathogenesis
10.1016/j.jmii.2020.07.022 · 2021 · External reference
Short communication: experimental toxocarosis in Chinese Kun Ming mice: dose-dependent larval distribution and modulation of immune responses
10.1016/j.rvsc.2015.09.002 · 2015 · External reference
Pooling of animal experimental data reveals influence of study design and publication bias
10.1161/01.str.0000125719.25853.20 · 2004 · External reference
The epidemiology and public health importance of toxocariasis: a zoonosis of global importance
10.1016/j.ijpara.2013.07.004 · 2013 · External reference
Detection of Toxocara canis DNA in tissues of experimentally infected mice
10.1016/j.actatropica.2018.07.017 · 2018 · External reference
Quantification of Toxocara canis DNA by qPCR in mice inoculated with different infective doses
10.1016/j.parint.2020.102134 · 2020 · External reference
10.1016/bs.apar.2020.01.003
10.1016/bs.apar.2020.01.003 · External reference
Humoral response of mice infected with Toxocara canis following different infection schemes
10.1515/ap-2017-0099 · 2017 · External reference
Toxocara canis infection worsens the course of experimental autoimmune encephalomyelitis in mice
10.1017/s0031182022001238 · 2022 · External reference
Biochemical and immunopathological changes in experimental neurotoxocariasis
10.1016/j.molbiopara.2010.03.006 · 2010 · External reference
Toxocara-induced hepatic inflammation: immunohistochemical characterization of lymphocyte subpopulations and Bcl-2 expression
10.1016/j.exppara.2013.02.001 · 2013 · External reference
Rayyan—a web and mobile app for systematic reviews
10.1186/s13643-016-0384-4 · 2016 · External reference
Production of eosinophil chemotactic factor by CD8+ T-cells in Toxocara canis-infected mice
10.1007/s004360050370 · 1998 · External reference
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
2021 · External reference
Influence of murine Toxocara canis infection on plasma and bronchoalveolar lavage fluid eosinophil numbers and its correlation with cytokine levels
10.1016/j.vetpar.2005.06.022 · 2005 · External reference
Persistent airway hyper-responsiveness and inflammation in Toxocara canis-infected BALB/c mice
10.1111/j.1365-2222.2005.02250.x · 2005 · External reference
Toxocara canis: effect of inoculum size on pulmonary pathology and cytokine expression in BALB/c mice
10.1016/j.exppara.2006.06.002 · 2007 · External reference
Infection with the roundworm Toxocara canis leads to exacerbation of experimental allergic airway inflammation
10.1111/j.1365-2222.2007.02908.x · 2008 · External reference
New insights into the immunopathology of early Toxocara canis infection in mice
10.1186/s13071-015-0962-7 · 2015 · External reference
Influence of maternal infection on offspring immune response in murine larval toxocariasis
10.1046/j.1365-3024.2003.00642.x · 2003 · External reference
Experimental toxocariasis in BALB/c mice: relationship between parasite inoculum and the IgG immune response
10.1590/0074-02760160341 · 2017 · External reference
Human toxocariasis – a look at a neglected disease through an epidemiological ‘prism’
10.1016/j.meegid.2019.104002 · 2019 · External reference
Human toxocariasis: diagnosis, worldwide seroprevalences and clinical expression of the systemic and ocular forms
10.1179/136485910x12607012373957 · 2010 · External reference
Immune response to chronic Toxocara canis infection in a mice model
10.1111/pim.12672 · 2019 · External reference
MMP-2/MMP-9 ocular toxocariasis
10.1007/s00436-018-06196-4 · 2019 · External reference
How common is human toxocariasis? Towards standardizing our knowledge
10.1016/j.pt.2009.01.006 · 2009 · External reference
Histopathological characterization of Toxocara canis- and T. cati-induced neurotoxocarosis in the mouse model
10.1007/s00436-019-06395-7 · 2019 · External reference
10.1016/bs.apar.2020.01.006
10.1016/bs.apar.2020.01.006 · External reference
Neuropathological studies of experimental toxocariasis in lead exposed mice
10.1016/0361-9230(83)90153-3 · 1983 · External reference
Eosinophilia, parasite burden and lung damage in Toxocara canis infection in C57BL/6 mice genetically deficient in IL-5
10.1046/j.1365-2567.1997.00208.x · 1997 · External reference
The role of ICAM-1/LFA-1 and VCAM-1/VLA-4 interactions on T helper 2 cytokine production by lung T cells of Toxocara canis-infected mice
10.1046/j.1365-2567.1998.00616.x · 1998 · External reference
No evidence of Alzheimer’s disease pathology in mice infected with Toxocara canis
10.1051/parasite/2025019 · 2025 · External reference
Neuroinvasion of Toxocara canis and T. cati larvae mediates dynamic changes in brain cytokine and chemokine profile
10.1186/s12974-019-1537-x · 2019 · External reference
Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and Toxocara cati-induced neurotoxocarosis
10.1371/journal.pntd.0007706 · 2019 · External reference
Toxocara canis- and Toxocara cati-induced neurotoxocarosis is associated with comprehensive brain transcriptomic alterations
10.3390/microorganisms10010177 · 2022 · External reference
Enhanced expression of transforming growth factor-β1 in inflammatory cells, α-smooth muscle actin in stellate cells, and collagen accumulation in experimental granulomatous hepatitis caused by Toxocara canis in mice
10.1016/j.actatropica.2007.11.005 · 2008 · External reference
Alterations of plasma circulating microRNAs in BALB/c mice with Toxocara canis visceral and cerebral larva migrans
10.1186/s13071-024-06327-0 · 2024 · External reference
Spatial transcriptomic atlas of murine neurotoxocariasis reveals region-specific host responses and dysfunction in the brain
10.1038/s41467-026-72114-3 · 2026 · External reference
