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References from Dual-layer interface-engineered milk extracellular vesicles improve the gastrointestinal stability and endothelial protective activity of the egg white-derived peptide QIGLF. Local targets link to admitted publications; unresolved targets remain external evidence.
Role of structural properties of bioactive peptides in their stability during simulated gastrointestinal digestion: A systematic review
10.1016/j.tifs.2022.01.008 · 2022 · External reference
Fenugreek-derived exosome-like nanovesicles containing bioavailable phytoferritin for the management of iron deficiency anemia
10.1016/j.foodchem.2025.145088 · 2025 · External reference
Physicochemical and in vitro digestion properties of gelatin/low-methoxyl pectin synbiotic microgels co-encapsulating Lacticaseibacillus casei and pectic oligosaccharides via double-crosslinking with transglutaminase and calcium ions
10.1016/j.foodhyd.2023.108757 · 2023 · External reference
The formulation and the release of low-methoxyl pectin liquid-core beads containing an emulsion of soybean isoflavones
10.1016/j.foodhyd.2022.107722 · 2022 · External reference
Sonication is a suitable method for loading nanobody into glioblastoma small extracellular vesicles
10.1016/j.heliyon.2023.e15674 · 2023 · External reference
The instability of pectin-based emulsions in the upper digestive tract investigated based on the molecular structure and interfacial properties of pectin
10.1016/j.carbpol.2024.122852 · 2025 · External reference
Advanced targeted curcumin delivery using biodegradable hierarchical microspheres with calcium pectinate matrix and hyaluronic acid moieties for enhancing colitis amelioration
10.1016/j.carbpol.2025.123273 · 2025 · External reference
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
10.1016/j.addr.2021.114097 · 2022 · External reference
Type A gelatin-amidated low methoxyl pectin complex coacervates for probiotics protection: Formation, characterization, and viability
10.1016/j.foodchem.2024.139644 · 2024 · External reference
Potential impact of bioactive peptides from foods in the treatment of hypertension
10.1002/mnfr.202400084 · 2024 · External reference
Endothelial dysfunction due to eNOS uncoupling: Molecular mechanisms as potential therapeutic targets
10.1186/s11658-023-00423-2 · 2023 · External reference
Impact of the drug loading method on the drug distribution and biological efficacy of exosomes
10.1208/s12249-023-02624-6 · 2023 · External reference
Endothelial dysfunction in obesity-induced inflammation: Molecular mechanisms and clinical implications
10.3390/biom10020291 · 2020 · External reference
Dual-Carriers of tartary buckwheat-derived exosome-like nanovesicles synergistically regulate glucose metabolism in the intestine-liver axis
10.1002/smll.202410124 · 2025 · External reference
Progress in peptide and protein therapeutics: Challenges and strategies
10.1016/j.apsb.2025.10.026 · 2025 · External reference
Targeted therapy using engineered extracellular vesicles: Principles and strategies for membrane modification
10.1186/s12951-023-02081-0 · 2023 · External reference
Milk extracellular vesicles: A burgeoning new presence in nutraceuticals and drug delivery
10.1002/btm2.10756 · 2025 · External reference
Effects of natural peptides from food proteins on angiotensin converting enzyme activity and hypertension
10.1080/10408398.2017.1402750 · 2019 · External reference
Multifunctional peptides from Spanish dry-cured pork ham: Endothelial responses and molecular modeling studies
10.3390/ijms20174204 · 2019 · External reference
Photoswitchable calixarene activators for controlled peptide transport across lipid membranes
10.1021/jacs.3c01829 · 2023 · External reference
Cartilage-targeting exosomes for delivery of receptor antagonist of interleukin-1 in osteoarthritis treatment
10.1016/j.joca.2025.02.785 · 2025 · External reference
Ultrasonication for production of nanoliposomes with encapsulated soy protein concentrate hydrolysate: Process optimization, vesicle characteristics and in vitro digestion
10.1016/j.fochx.2022.100370 · 2022 · External reference
Exploiting the role of milk extracellular vesicles: A comprehensive analysis on isolation methods, characterization, surface modifications, and their therapeutic applications
10.1186/s12951-026-04058-1 · 2026 · External reference
Therapeutic potential of bovine milk-derived extracellular vesicles
10.3390/ijms25105543 · 2024 · External reference
Current trends and applications of food-derived antihypertensive peptides for the management of cardiovascular disease
10.2174/0929866529666220106100225 · 2022 · External reference
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota
10.7150/thno.62046 · 2021 · External reference
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡdelta to inhibit ROS-mediated NF-kappaB/NLRP3 in cardiomyocytes
10.1016/j.redox.2024.103223 · 2024 · External reference
Oral administration of Robinia pseudoacacia L. flower exosome-like nanoparticles attenuates gastric and small intestinal mucosal ferroptosis caused by hypoxia through inhibiting HIF-1α- and HIF-2α-mediated lipid peroxidation
2024 · External reference
Engineering extracellular vesicles as delivery systems in therapeutic applications
10.1002/advs.202300552 · 2023 · External reference
Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway
10.1093/cvr/cvad086 · 2023 · External reference
Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective properties: In silico and in vitro studies
10.1016/j.crfs.2025.101135 · 2025 · External reference
A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function
10.1016/j.jare.2025.02.005 · 2025 · External reference
Potential antihypertensive mechanisms of the egg white-derived peptide QIGLF in spontaneously hypertensive rats revealed using untargeted serum metabolomics
10.1021/acs.jafc.1c05599 · 2021 · External reference
Short- and long-term antihypertensive effect of egg protein-derived peptide QIGLF
10.1002/jsfa.7762 · 2017 · External reference
Underlying antihypertensive mechanism of egg white-derived peptide QIGLF using renal metabolomics analysis
10.1016/j.foodres.2022.111457 · 2022 · External reference
Sodium alginate/low methoxyl pectin composite hydrogel beads prepared gas-shearing technology for enhancing the colon-targeted delivery of probiotics and modulating gut microbiota
10.1016/j.ijbiomac.2025.140375 · 2025 · External reference
Dual crosslinking of folic acid-modified pectin nanoparticles for enhanced oral insulin delivery
10.1016/j.bioadv.2022.212746 · 2022 · External reference
Food-derived exosomes as a new generation of targeted colonic delivery materials: Advantages and potential
2026 · External reference
Gut-liver axis: Potential mechanisms of action of food-derived extracellular vesicles
10.1002/jev2.12466 · 2024 · External reference
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: Innovative strategies of therapeutic and drug delivery
10.7150/thno.97096 · 2024 · External reference
Multifunctional milk-derived small extracellular vesicles and their biomedical applications
10.3390/pharmaceutics15051418 · 2023 · External reference
Potential antihypertensive mechanism of egg white-derived peptide QIGLF revealed by proteomic analysis (vol 218, pg 439, 2022)
10.1016/j.ijbiomac.2024.130925 · 2024 · External reference
Engineering extracellular vesicles as delivery systems in therapeutic applications
10.1002/advs.202300552 · ExternalCitation · doi-reference
Milk extracellular vesicles: A burgeoning new presence in nutraceuticals and drug delivery
10.1002/btm2.10756 · ExternalCitation · doi-reference
Gut-liver axis: Potential mechanisms of action of food-derived extracellular vesicles
10.1002/jev2.12466 · ExternalCitation · doi-reference
Short- and long-term antihypertensive effect of egg protein-derived peptide QIGLF
10.1002/jsfa.7762 · ExternalCitation · doi-reference
Potential impact of bioactive peptides from foods in the treatment of hypertension
10.1002/mnfr.202400084 · ExternalCitation · doi-reference
Dual-Carriers of tartary buckwheat-derived exosome-like nanovesicles synergistically regulate glucose metabolism in the intestine-liver axis
10.1002/smll.202410124 · ExternalCitation · doi-reference
Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
10.1016/j.addr.2021.114097 · ExternalCitation · doi-reference
Progress in peptide and protein therapeutics: Challenges and strategies
10.1016/j.apsb.2025.10.026 · ExternalCitation · doi-reference
Dual crosslinking of folic acid-modified pectin nanoparticles for enhanced oral insulin delivery
10.1016/j.bioadv.2022.212746 · ExternalCitation · doi-reference
The instability of pectin-based emulsions in the upper digestive tract investigated based on the molecular structure and interfacial properties of pectin
10.1016/j.carbpol.2024.122852 · ExternalCitation · doi-reference
Advanced targeted curcumin delivery using biodegradable hierarchical microspheres with calcium pectinate matrix and hyaluronic acid moieties for enhancing colitis amelioration
10.1016/j.carbpol.2025.123273 · ExternalCitation · doi-reference
Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (Juglans sigillata Dode) protein hydrolysates and their vascular endothelial protective properties: In silico and in vitro studies
10.1016/j.crfs.2025.101135 · ExternalCitation · doi-reference
Ultrasonication for production of nanoliposomes with encapsulated soy protein concentrate hydrolysate: Process optimization, vesicle characteristics and in vitro digestion
10.1016/j.fochx.2022.100370 · ExternalCitation · doi-reference
Type A gelatin-amidated low methoxyl pectin complex coacervates for probiotics protection: Formation, characterization, and viability
10.1016/j.foodchem.2024.139644 · ExternalCitation · doi-reference
Fenugreek-derived exosome-like nanovesicles containing bioavailable phytoferritin for the management of iron deficiency anemia
10.1016/j.foodchem.2025.145088 · ExternalCitation · doi-reference
The formulation and the release of low-methoxyl pectin liquid-core beads containing an emulsion of soybean isoflavones
10.1016/j.foodhyd.2022.107722 · ExternalCitation · doi-reference
Physicochemical and in vitro digestion properties of gelatin/low-methoxyl pectin synbiotic microgels co-encapsulating Lacticaseibacillus casei and pectic oligosaccharides via double-crosslinking with transglutaminase and calcium ions
10.1016/j.foodhyd.2023.108757 · ExternalCitation · doi-reference
Underlying antihypertensive mechanism of egg white-derived peptide QIGLF using renal metabolomics analysis
10.1016/j.foodres.2022.111457 · ExternalCitation · doi-reference
Sonication is a suitable method for loading nanobody into glioblastoma small extracellular vesicles
10.1016/j.heliyon.2023.e15674 · ExternalCitation · doi-reference
Potential antihypertensive mechanism of egg white-derived peptide QIGLF revealed by proteomic analysis (vol 218, pg 439, 2022)
10.1016/j.ijbiomac.2024.130925 · ExternalCitation · doi-reference
Sodium alginate/low methoxyl pectin composite hydrogel beads prepared gas-shearing technology for enhancing the colon-targeted delivery of probiotics and modulating gut microbiota
10.1016/j.ijbiomac.2025.140375 · ExternalCitation · doi-reference
A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function
10.1016/j.jare.2025.02.005 · ExternalCitation · doi-reference
Cartilage-targeting exosomes for delivery of receptor antagonist of interleukin-1 in osteoarthritis treatment
10.1016/j.joca.2025.02.785 · ExternalCitation · doi-reference
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡdelta to inhibit ROS-mediated NF-kappaB/NLRP3 in cardiomyocytes
10.1016/j.redox.2024.103223 · ExternalCitation · doi-reference
Role of structural properties of bioactive peptides in their stability during simulated gastrointestinal digestion: A systematic review
10.1016/j.tifs.2022.01.008 · ExternalCitation · doi-reference
Potential antihypertensive mechanisms of the egg white-derived peptide QIGLF in spontaneously hypertensive rats revealed using untargeted serum metabolomics
10.1021/acs.jafc.1c05599 · ExternalCitation · doi-reference
Photoswitchable calixarene activators for controlled peptide transport across lipid membranes
10.1021/jacs.3c01829 · ExternalCitation · doi-reference
Effects of natural peptides from food proteins on angiotensin converting enzyme activity and hypertension
10.1080/10408398.2017.1402750 · ExternalCitation · doi-reference
Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway
10.1093/cvr/cvad086 · ExternalCitation · doi-reference
Endothelial dysfunction due to eNOS uncoupling: Molecular mechanisms as potential therapeutic targets
10.1186/s11658-023-00423-2 · ExternalCitation · doi-reference
Targeted therapy using engineered extracellular vesicles: Principles and strategies for membrane modification
10.1186/s12951-023-02081-0 · ExternalCitation · doi-reference
Exploiting the role of milk extracellular vesicles: A comprehensive analysis on isolation methods, characterization, surface modifications, and their therapeutic applications
10.1186/s12951-026-04058-1 · ExternalCitation · doi-reference
Impact of the drug loading method on the drug distribution and biological efficacy of exosomes
10.1208/s12249-023-02624-6 · ExternalCitation · doi-reference
Current trends and applications of food-derived antihypertensive peptides for the management of cardiovascular disease
10.2174/0929866529666220106100225 · ExternalCitation · doi-reference
Endothelial dysfunction in obesity-induced inflammation: Molecular mechanisms and clinical implications
10.3390/biom10020291 · ExternalCitation · doi-reference
Multifunctional peptides from Spanish dry-cured pork ham: Endothelial responses and molecular modeling studies
10.3390/ijms20174204 · ExternalCitation · doi-reference
Therapeutic potential of bovine milk-derived extracellular vesicles
10.3390/ijms25105543 · ExternalCitation · doi-reference
Multifunctional milk-derived small extracellular vesicles and their biomedical applications
10.3390/pharmaceutics15051418 · ExternalCitation · doi-reference
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota
10.7150/thno.62046 · ExternalCitation · doi-reference
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: Innovative strategies of therapeutic and drug delivery
10.7150/thno.97096 · ExternalCitation · doi-reference
