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References from Inhibitory properties of grapefruit juice components on human cytochrome P450 3A5 activity. Local targets link to admitted publications; unresolved targets remain external evidence.
Analysis of inhibition kinetics of three beverage ingredients, bergamottin, dihydroxybergamottin and resveratrol, on CYP2C9 activity
10.1016/j.dmpk.2021.100429 · 2022 · External reference
10.1016/s0021-9258(18)81632-5
10.1016/s0021-9258(18)81632-5 · 1989 · External reference
Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin
10.1038/clpt.1993.84 · 1993 · External reference
Interaction of citrus juices with felodipine and nifedipine
10.1016/0140-6736(91)90872-m · 1991 · External reference
Mata-analysis of the turnover of intestinal epithelia in preclinical animal species and humans
10.1124/dmd.114.058404 · 2014 · External reference
Identification and functional characterization of eight CYP3A4 protein variants
10.1097/00008571-200107000-00008 · 2001 · External reference
Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population
10.1097/00008571-200206000-00009 · 2002 · External reference
Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population
10.1002/humu.9210 · 2004 · External reference
Determination of CYP450 expression levels in the human small intestine by mass spectrometry-based targeted proteomics
10.3390/ijms222312791 · 2021 · External reference
Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines
2004 · External reference
Grapefruit juice inhibits the metabolic activation of clopidogrel
10.1038/clpt.2013.192 · 2014 · External reference
High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli
10.1016/s0006-2952(97)00643-6 · 1998 · External reference
Effect of CYP3A5 gene polymorphisms on tacrolimus blood concentrations and adverse events in allogeneic hematopoietic stem cell transplant patients
10.1016/j.transproceed.2024.08.012 · 2024 · External reference
Drug interaction of efavirenz and midazolam: Efavirenz activates the CYP3A-mediated midazolam 1'-hydroxylation in vitro
10.1124/dmd.111.043844 · 2012 · External reference
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
10.1038/86882 · 2001 · External reference
Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
10.1097/00008571-200203000-00006 · 2002 · External reference
Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups
10.1097/00008571-200308000-00004 · 2003 · External reference
Influence of CYP3A5 and MDR1 genetic polymorphisms on urinary 6 beta-hydroxycortisol/cortisol ratio after grapefruit juice intake in healthy Chinese
10.1177/0091270009354997 · 2010 · External reference
In vitro and in silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
10.1016/j.toxrep.2022.03.040 · 2022 · External reference
Protein-Ligand identification and in vitro inhibitory effects of cathine on 11 major human drug metabolizing cytochrome P450s
10.1177/10915818221103790 · 2022 · External reference
The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5
10.1124/jpet.104.079608 · 2005 · External reference
Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men
10.1007/s002280050263 · 1997 · External reference
Comparison of the contributions of cytochromes P450 3A4 and 3A5 in drug oxidation rates and substrate inhibition
10.1248/jhs.56.239 · 2010 · External reference
Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions
10.1124/dmd.106.012633 · 2007 · External reference
The carbon monoxide-binding pigment of liver microsomes. II. SOLUBILIZATION, purification, and properties
10.1016/s0021-9258(20)82245-5 · 1964 · External reference
Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties
10.1124/dmd.104.000547 · 2004 · External reference
The human intestinal cytochrome P450 "pie"
10.1124/dmd.105.008672 · 2006 · External reference
Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice
10.1111/j.1365-2125.1993.tb00396.x · 1993 · External reference
Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices
10.1016/s0026-895x(24)12051-2 · 2000 · External reference
Contents of furanocoumarins in grapefruit juice and health foods
10.3358/shokueishi.49.326 · 2008 · External reference
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity
10.1067/mcp.2000.104391 · 2000 · External reference
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins
1997 · External reference
Inhibitory kinetics of fruit components on CYP2C19 activity
10.1016/j.dmpk.2019.02.002 · 2019 · External reference
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians
10.1016/s0022-3565(25)22379-5 · 1994 · External reference
Simultaneous determination of •-agonists and psychiatric drugs in feeds by LC-MS-MS
10.1093/chromsci/bmt084 · 2014 · External reference
Impact of CYP3A5 genetic polymorphism on pharmacokinetics of tacrolimus in healthy Japanese subjects
10.1111/j.1365-2125.2008.03162.x · 2008 · External reference
Relationship between time after intake of grapefruit juice and the effect on pharmacokinetics and pharmacodynamics of nisoldipine in healthy subjects
10.1067/mcp.2000.104215 · 2000 · External reference