Research graph
References from Multi-omics prioritization identifies ISG20 as a candidate molecular target of patulin in colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Changes of reduced glutathione and glutathione S-transferase levels in colorectal cancer patients undergoing treatment
10.5301/tj.5000674 · 2018 · External reference
Oxidative stress, inflammation and colorectal cancer: an overview
2023 · External reference
The role of oxidative stress and its counteractive utility in colorectal cancer (CRC)
10.3390/cancers12113336 · 2020 · External reference
ISG20 stimulates anti-tumor immunity via a double-stranded RNA-induced interferon response in ovarian cancer
2023 · External reference
The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals
10.3389/fimmu.2022.958898 · 2022 · External reference
ISG20: an enigmatic antiviral RNase targeting multiple viruses
10.1002/2211-5463.13382 · 2022 · External reference
Commission Regulation (EU) 2023/915 of 25 April 2023 on maximum levels for certain contaminants in food and repealing Regulation (EC) No 1881/2006
2023 · External reference
ISG20 promotes local tumor immunity and contributes to poor survival in human glioma
10.1080/2162402x.2018.1534038 · 2019 · External reference
A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential
10.1186/s12885-019-5768-0 · 2019 · External reference
Molecular cloning of a new interferon-induced PML nuclear body-associated protein
10.1074/jbc.272.31.19457 · 1997 · External reference
Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets
10.1007/s13277-013-0842-8 · 2013 · External reference
International Agency for Research on Cancer
2014 · External reference
p53 activation contributes to patulin-induced nephrotoxicity via modulation of reactive oxygen species generation
2016 · External reference
Glutathione S-transferase (GST) gene polymorphisms, cigarette smoking and colorectal cancer risk among Chinese in Singapore
10.1093/carcin/bgr175 · 2011 · External reference
10-Eicosanol alleviates patulin-induced cell cycle arrest and apoptosis by activating AKT (protein kinase B) in porcine intestinal epithelial cells
2024 · External reference
Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
10.1016/j.tranon.2021.101221 · 2021 · External reference
Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA
10.1371/journal.ppat.1006296 · 2017 · External reference
The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro
10.1021/bi010141t · 2001 · External reference
Toxicological effects of patulin mycotoxin on the mammalian system: an overview
10.1039/c7tx00138j · 2017 · External reference
Inflammatory cytokines and oxidative stress markers in relation to colorectal cancer risk: a case-cohort study in a Korean population
10.3390/cancers18030470 · 2026 · External reference
The characteristics, occurrence, and toxicological effects of patulin
10.1016/j.fct.2019.04.036 · 2019 · External reference
Reduction of blood oxidative stress following colorectal cancer resection
10.3390/cancers16203550 · 2024 · External reference
The inflammatory pathogenesis of colorectal cancer
10.1038/s41577-021-00534-x · 2021 · External reference
COX-2/EP2-EP4/β-catenin signaling regulates patulin-induced intestinal cell proliferation and inflammation
10.1016/j.taap.2018.08.009 · 2018 · External reference
Transcriptomic and proteomic insights into patulin mycotoxin-induced cancer-like phenotypes in normal intestinal epithelial cells
10.1007/s11010-022-04387-3 · 2022 · External reference
MMP3 and CXCL1 are potent stromal protein markers of dysplasia-carcinoma transition in sporadic colorectal cancer
10.1097/cej.0000000000000058 · 2014 · External reference
Deletion and single nucleotide polymorphisms in common Glutathione-S transferases contribute to colorectal cancer development
10.1007/s12253-019-00589-1 · 2019 · External reference
The role of glutathione-S-transferase in anti-cancer drug resistance
10.1038/sj.onc.1206940 · 2003 · External reference
Matrix metalloproteinase 3: a promoting and destabilizing factor in the pathogenesis of disease and cell differentiation
10.3389/fphys.2021.663978 · 2021 · External reference
Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by upregulating STAT3
10.17219/acem/142461 · 2022 · External reference
Significance of serum total oxidant/antioxidant status in patients with colorectal cancer
2017 · External reference
ISG20 serves as a potential biomarker and drives tumor progression in clear cell renal cell carcinoma
10.18632/aging.102714 · 2020 · External reference
Integrated transcriptomics and metabolomics reveal the mechanism of intestinal damage upon acute patulin exposure in mice
10.1016/j.ecoenv.2024.116270 · 2024 · External reference
