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References from Pile-fermentation and golden-flower fermentation reshape tea polysaccharides in Tibetan dark tea: structural characteristics and lipid-modulating effects in Caenorhabditis elegans. Local targets link to admitted publications; unresolved targets remain external evidence.
Obesity: A Global Health challenge demanding urgent action
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Application of Caenorhabditis elegans in lipid metabolism research
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The combination of metformin and high glucose increased longevity of Caenorhabditis elegans a DAF-16/FOXO-independent manner: cancer/diabetic model via C. Elegans
10.3389/fendo.2024.1435098 · 2024 · External reference
PGC-1α-mediated imbalance of mitochondria-lipid droplet homeostasis in neomycin-induced ototoxicity and nephrotoxicity
10.1016/j.apsb.2024.05.024 · 2024 · External reference
Multi-omics analysis reveals the sensory quality and fungal communities of Tibetan teas produced by wet- and dry-piling fermentation
10.1016/j.foodres.2025.115690 · 2025 · External reference
Formation, physicochemical properties, and biological activities of theabrownins
10.1016/j.foodchem.2024.139140 · 2024 · External reference
Qimen An tea with different storage years exhibits anti-obesity activity and differently modulates gut microbiota in a year-dependent manner
10.1016/j.fbio.2025.106121 · 2025 · External reference
Colorimetric method for determination of sugars and related substances
10.1021/ac60111a017 · 1956 · External reference
10.1002/fsn3.70523
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Anti-obesity mechanisms of plant and fungal polysaccharides: The impact of structural diversity
10.3390/biom15081140 · 2025 · External reference
Conversion of (poly)phenolic compounds in food fermentations by lactic acid bacteria: Novel insights into metabolic pathways and functional metabolites
10.1016/j.crfs.2023.100448 · 2023 · External reference
Caenorhabditis elegans as a screening model for probiotics with properties against metabolic syndrome
10.3390/ijms25021321 · 2024 · External reference
Reshaped local microbiology metabolism by raw tea according to pile fermentation in the dark tea
10.1016/j.jare.2025.02.039 · 2025 · External reference
Lipoxygenase and leukotriene pathways: Biochemistry, biology, and roles in disease
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Extraction methods, chemical compositions, molecular structure, health functions, and potential applications of tea polysaccharides as a promising biomaterial: A review
10.1016/j.ijbiomac.2024.134150 · 2024 · External reference
Nuclear receptors in health and disease: Signaling pathways, biological functions and pharmaceutical interventions
10.1038/s41392-025-02270-3 · 2025 · External reference
Low molecular weight polysaccharide of Tremella fuciformis exhibits stronger antioxidant and immunomodulatory activities than high molecular weight polysaccharide
10.1016/j.ijbiomac.2024.136097 · 2024 · External reference
Trends in insulin resistance: Insights into mechanisms and therapeutic strategy
10.1038/s41392-022-01073-0 · 2022 · External reference
Effects of pile fermentation on the physicochemical, functional, and biological properties of tea polysaccharides
10.1016/j.foodchem.2022.135353 · 2023 · External reference
Perfluorooctane sulfonate promotes hepatic lipid accumulation and steatosis in high-fat diet mice through AMP-activated protein kinase/acetyl-CoA carboxylase (AMPK/ACC) pathway
10.1002/jat.4383 · 2023 · External reference
Theabrownin: The ‘rich hue’ of Chinese dark tea, its extraction, and role in regulating inflammation and immune response
10.1016/j.foodres.2025.116185 · 2025 · External reference
Composition, antioxidant and development-promoting activity of fermentation modified crude polysaccharides from stem and leaves of Chenopodium album L
10.1186/s40538-024-00610-z · 2024 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method
10.1006/meth.2001.1262 · 2001 · External reference
Instant steam-priming as a novel pre-brewing strategy: Unraveling the metabolomic basis for modulating taste attributes across six tea categories
10.1016/j.foodres.2026.118489 · 2026 · External reference
Effects of microbial fermentation on tea in alleviating obesity symptoms: Insights from microbiome and metabolomics
10.1016/j.foodres.2025.116111 · 2025 · External reference
Characterization of selenium tea polysaccharides from black tea
10.1016/j.foodchem.2026.149045 · 2026 · External reference
Maintenance of C. Elegans
2006 · External reference
Metabolomic and transcriptomic analyses reveal comparisons against liquid-state fermentation of primary dark tea, green tea and white tea by aspergillus cristatus
10.1016/j.foodres.2023.113115 · 2023 · External reference
Differential characteristics of chemical composition, fermentation metabolites and antioxidant effects of polysaccharides from Eurotium Cristatum and Fu-brick tea
10.1016/j.foodchem.2024.140934 · 2024 · External reference
Lipid peroxidation and antioxidant protection
10.3390/biom13091291 · 2023 · External reference
Tea polysaccharide’s role in inhibited protein alterations of <i>Hypophthalmichthys molitrix</i> and in-depth molecular interaction mechanism during fluctuated frozen storage
10.1016/j.lwt.2025.117568 · 2025 · External reference
Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans
10.1038/s41467-022-28469-4 · 2022 · External reference
Comprehensive evaluation of extraction process, physicochemical properties and bioactivities of hawk tea polysaccharides: Comparison of ultrasonic and hot water extraction
10.1016/j.ultsonch.2025.107477 · 2025 · External reference
Impact of aspergillus cristatus dominated fermentation on fungal communities and metabolite profiling in large-leaf tea: Insights into quality formation via post-fermentation “flowering” process
10.1016/j.fbio.2025.106890 · 2025 · External reference
Structural characterization and in vitro antioxidant, hypoglycemic and hypolipemic activities of a natural polysaccharide from Liupao tea
10.3390/foods12112226 · 2023 · External reference
Multidimensional analysis reveals the flavor quality formation mechanism during the primary pile fermentation of dark tea
10.3390/foods15020212 · 2026 · External reference
Ultrasonic modification on the physicochemical, in vitro simulated digestion and colonic fermentation properties of Golden flower Tibetan tea polysaccharides
10.1016/j.lwt.2025.118256 · 2025 · External reference
Antioxidant and hypoglycemic activity of tea polysaccharides with different degrees of fermentation
10.1016/j.ijbiomac.2022.12.114 · 2023 · External reference
Compositions and antioxidant activity of tea polysaccharides extracted from different tea (Camellia sinensis L.) varieties
10.3390/foods12193584 · 2023 · External reference
The preventive effect of Theabrownin from ya’an Tibetan tea against UVB-induced skin Photodamage in BALB/c mice via the MAPK/NF-κB and Nrf2 signaling pathways
10.3390/foods14040600 · 2025 · External reference
The mechanism of traditional medicine in alleviating ulcerative colitis: Regulating intestinal barrier function
10.3389/fphar.2023.1228969 · 2023 · External reference
A polysaccharide from green tea (Camellia sinensis L.) protects human retinal endothelial cells against hydrogen peroxide-induced oxidative injury and apoptosis
10.1016/j.ijbiomac.2018.04.011 · 2018 · External reference
Structural characterization and combined immunomodulatory activity of fermented Chinese yam polysaccharides with probiotics
10.1016/j.ijbiomac.2025.142290 · 2025 · External reference
Phytochemicals from fractioned dark tea water extract enhance the digestive enzyme inhibition, antioxidant capacities and glucose-lipid balance
10.1016/j.foodres.2025.115957 · 2025 · External reference
Golden flower Tibetan tea polysaccharides alleviate constipation in mice by regulating Aquaporins-mediated water transport system and gut microbiota
10.3390/foods13172749 · 2024 · External reference
Polystyrene microplastics (PS-MPs) toxicity induced oxidative stress and intestinal injury in nematode Caenorhabditis elegans
10.1016/j.scitotenv.2020.138679 · 2020 · External reference
Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice
10.1016/j.tox.2021.153088 · 2022 · External reference
Resveratrol alleviates inflammatory bowel disease by inhibiting JAK2/STAT3 pathway activity via the reduction of O-GlcNAcylation of STAT3 in intestinal epithelial cells
2024 · External reference
Recent insights into the physicochemical properties, bioactivities and their relationship of tea polysaccharides
10.1016/j.foodchem.2023.137223 · 2024 · External reference
Fermented food-polysaccharides as gut health regulators: Sources, optimization, structural characteristics and mechanism
10.3390/foods14234108 · 2025 · External reference