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References from Untargeted lipidomics-guided characterization of neuroprotective and neurotrophic activities of ethanol-modified supercritical carbon dioxide coffee pulp extracts. Local targets link to admitted publications; unresolved targets remain external evidence.
Enhanced extraction of spent coffee grounds oil using high-pressure CO2 plus ethanol solvents
10.1016/j.indcrop.2019.111723 · 2019 · External reference
CLAW-MRM: Comprehensive lipidomics automation workflow for multiple reaction monitoring using large language models
10.1021/acs.analchem.4c05039 · 2025 · External reference
Coffee pulp, a by-product of coffee production, modulates gut microbiota and improves metabolic syndrome in high-carbohydrate, high-fat diet-fed rats
10.3390/pathogens10111369 · 2021 · External reference
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
10.1016/0003-2697(76)90527-3 · 1976 · External reference
Quantitative lipidomics in green robusta coffees from the Brazilian Amazon by LC-HRMS
10.1016/j.fbio.2023.103472 · 2024 · External reference
Coffee pulp simulated digestion enhances its in vitro ability to decrease emulsification and digestion of fats, and attenuates lipid accumulation in HepG2 cell model
10.1016/j.crfs.2024.100804 · 2024 · External reference
INFOGEST static in vitro simulation of gastrointestinal food digestion
10.1038/s41596-018-0119-1 · 2019 · External reference
Neuroprotective properties of coffee: An update
10.1016/j.tifs.2021.04.052 · 2021 · External reference
Supercritical CO2 extraction of spent coffee grounds. Influence of co-solvents and characterization of the extracts
10.1016/j.supflu.2020.104825 · 2020 · External reference
Food grade extraction of Chlorella vulgaris polar lipids: A comparative lipidomic study
10.1016/j.foodchem.2021.131685 · 2022 · External reference
Potential of microalgal lipids to prevent intestinal barrier disruption: A case study exploring the response of Caco-2 cells to the food contaminant deoxynivalenol
10.1016/j.jff.2025.107125 · 2025 · External reference
Mechanistic insights into aroma enhancement of Robusta coffee through ultrasound synergistic oil-solvent pretreatment: A combined lipidomics and volatilomics approach
10.1016/j.foodchem.2025.146134 · 2025 · External reference
Lipidomics insight on differences in lipid profiles and phytosterol compositions of coconut oils extracted by classical and green solvents
10.1016/j.foodres.2023.113653 · 2023 · External reference
Bioavailability and bioaccessibility of food bioactive compounds; overview and assessment by in vitro methods
10.1111/1541-4337.12623 · 2020 · External reference
Gut–brain communication mediates the impact of dietary lipids on cognitive capacity
10.1039/d3fo05288e · 2024 · External reference
A simple method for the isolation and purification of total lipides from animal tissues
10.1016/s0021-9258(18)64849-5 · 1957 · External reference
Unveiling the nutritional profile and safety of coffee pulp as a first step in its valorization strategy
10.3390/foods13183006 · 2024 · External reference
Metabolic effects of gastric bypass surgery: Is it all about calories?
10.2337/db20-0131 · 2020 · External reference
Valorization of coffee pulp as bioactive food ingredient by sustainable extraction methodologies
10.1016/j.crfs.2023.100475 · 2023 · External reference
Tailored recovery of antioxidant fractions enriched in caffeine and phenolic compounds from coffee pulp using ethanol-modified supercritical carbon dioxide
10.1016/j.foodres.2024.115433 · 2025 · External reference
Intestinal oxidative stress mitigation and transepithelial anti-inflammatory bioactivity mediated by EtOH-modified supercritical-CO2 coffee pulp extract
10.1039/d6fo00489j · 2026 · External reference
Lipids as biomarkers of brain disorders
10.1080/10408398.2018.1529653 · 2020 · External reference
Unresolved reference
2009 · External reference
Ether lipid-mediated antioxidant defense in Alzheimer's disease
10.3390/antiox12020293 · 2023 · External reference
Emerging analytical techniques for lipid profiling in food products: Insights into processing effects and quality control
2025 · External reference
Coupling in vitro food digestion with in vitro epithelial absorption; recommendations for biocompatibility
2024 · External reference
Coffee cherry on the top: Disserting valorization of coffee pulp and husk
10.1007/s12393-023-09352-4 · 2024 · External reference
Neurogenesis using P19 embryonal carcinoma cells
2019 · External reference
Effects of ultra-high pressure processing on microstructure, water distribution and lipidomics variances of Arabica coffee beans
10.1016/j.lwt.2024.116784 · 2024 · External reference
Enhancing lipidomics with high-resolution ion mobility-mass spectrometry
10.1002/pmic.70026 · 2026 · External reference
Valorisation of coffee roasting by-products: Recovery of silverskin fat by supercritical CO2 extraction
10.1007/s12649-021-01435-9 · 2021 · External reference
Nootropic foods in neurodegenerative diseases: Mechanisms, challenges, and future
10.1186/s40035-025-00476-7 · 2025 · External reference
Lipidomic alterations in the cerebral cortex and white matter in sporadic Alzheimer’s disease
10.14336/ad.2023.0217 · 2023 · External reference
Lipophilic and hydrophilic metabolites as descriptors of different coffee beverages
10.1021/acs.jafc.4c03347 · 2024 · External reference
Effect of the roast level on lipophilic and hydrophilic compounds in pot and filter coffee beverages
10.1021/acsfoodscitech.5c00066 · 2025 · External reference
pkCSM: Predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
10.1021/acs.jmedchem.5b00104 · 2015 · External reference
Caffeine inhibits acetylcholinesterase, but not butyrylcholinesterase
10.3390/ijms14059873 · 2013 · External reference
Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
10.1038/s44321-025-00349-6 · 2026 · External reference
Supercritical fluid extraction to obtain ceramides from wool fibers
10.1016/j.seppur.2008.06.014 · 2008 · External reference
Interactions of dietary polyphenols with epithelial lipids: Advances from membrane and cell models in the study of polyphenol absorption, transport and delivery to the epithelium
10.1080/10408398.2020.1791794 · 2021 · External reference
Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects
10.1017/s0007114512005338 · 2013 · External reference
Coffee oil extraction methods: A review
10.3390/foods13162601 · 2024 · External reference
Supercritical CO2 extraction of lipids from coffee silverskin: From laboratory optimization to industrial scale-up
10.1016/j.scp.2025.102001 · 2025 · External reference
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets
10.1371/journal.pbio.3003349 · 2025 · External reference
Plasma sphingolipids and risk of cardiovascular diseases: A large-scale lipidomic analysis
10.1007/s11306-020-01709-8 · 2020 · External reference
Comparison of chemical compositions, antioxidant activities, and acetylcholinesterase inhibitory activities between coffee flowers and leaves as potential novel foods
10.1002/fsn3.3126 · 2023 · External reference
Comprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
10.1016/j.foodres.2020.109727 · 2020 · External reference
Lipid characterization of Arabica and Robusta coffee beans by liquid chromatography-ion mobility-mass spectrometry
10.1016/j.jfca.2022.104587 · 2022 · External reference
Phospholipid and lipid derivatives as potential neuroprotective compounds
10.3390/molecules23092257 · 2018 · External reference
Supercritical carbon dioxide and ethanol-assisted extraction of bioactive compounds from Bourbon, Catimor, and Caturra coffee pulp for maximized antioxidant and therapeutic properties
10.1016/j.fufo.2024.100381 · 2024 · External reference
Fatty acid composition and sensory properties as descriptors of differentiation of specialty coffees based on spontaneous and induced processing methods
10.1016/j.afres.2024.100512 · 2024 · External reference
Lipidomic characterization of polar and non-polar lipids in egg yolk and their anti-inflammatory and analgesic activities in zebrafish
10.1016/j.foodchem.2025.142855 · 2025 · External reference
Quantitative lipidomics reveals the effects of roasting degree on Arabica coffee beans lipid profiles
10.1016/j.foodcont.2024.111015 · 2025 · External reference
Comparative lipidomics analysis reveals changes in lipid profile of Arabica coffee at different maturity
2024 · External reference
Guidelines for in vitro simulated digestion and absorption of food
10.1002/fft2.186 · 2023 · External reference
Brain lipidomics: From functional landscape to clinical significance
10.1126/sciadv.adc9317 · 2022 · External reference
Comparative characterization of lipid composition and minor components in coffee oils from Arabica and Robusta spent coffee grounds
10.3390/foods15122129 · 2026 · External reference
Lipidomics reveals the effects of various processing parameters on the lipid composition and activity of roasted coffee oil
10.1016/j.lwt.2024.116938 · 2024 · External reference
Coffee and tea intake, dementia risk, and cognitive function
10.1001/jama.2025.27259 · 2026 · External reference
Dietary bioactive lipids: A review on absorption, metabolism, and health properties
10.1021/acs.jafc.1c01369 · 2021 · External reference
Insights into the role of copper in neurodegenerative diseases and the therapeutic potential of natural compounds
10.2174/1570159x22666231103085859 · 2024 · External reference
Applications of the INFOGEST in vitro digestion model to foods: A review
10.1146/annurev-food-060721-012235 · 2023 · External reference
Revealing the dynamic changes of lipids in coffee beans during roasting based on UHPLC-QE-HR-AM/MS/MS
10.1016/j.foodres.2023.113507 · 2023 · External reference
PI3K/Akt and ERK1/2 signalling are involved in quercetin-mediated neuroprotection against copper-induced injury
10.1155/2020/9834742 · 2020 · External reference
Coffee and tea intake, dementia risk, and cognitive function
10.1001/jama.2025.27259 · ExternalCitation · doi-reference
Guidelines for in vitro simulated digestion and absorption of food
10.1002/fft2.186 · ExternalCitation · doi-reference
Comparison of chemical compositions, antioxidant activities, and acetylcholinesterase inhibitory activities between coffee flowers and leaves as potential novel foods
10.1002/fsn3.3126 · ExternalCitation · doi-reference
Enhancing lipidomics with high-resolution ion mobility-mass spectrometry
10.1002/pmic.70026 · ExternalCitation · doi-reference
Plasma sphingolipids and risk of cardiovascular diseases: A large-scale lipidomic analysis
10.1007/s11306-020-01709-8 · ExternalCitation · doi-reference
Coffee cherry on the top: Disserting valorization of coffee pulp and husk
10.1007/s12393-023-09352-4 · ExternalCitation · doi-reference
Valorisation of coffee roasting by-products: Recovery of silverskin fat by supercritical CO2 extraction
10.1007/s12649-021-01435-9 · ExternalCitation · doi-reference
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
10.1016/0003-2697(76)90527-3 · ExternalCitation · doi-reference
Fatty acid composition and sensory properties as descriptors of differentiation of specialty coffees based on spontaneous and induced processing methods
10.1016/j.afres.2024.100512 · ExternalCitation · doi-reference
Valorization of coffee pulp as bioactive food ingredient by sustainable extraction methodologies
10.1016/j.crfs.2023.100475 · ExternalCitation · doi-reference
Coffee pulp simulated digestion enhances its in vitro ability to decrease emulsification and digestion of fats, and attenuates lipid accumulation in HepG2 cell model
10.1016/j.crfs.2024.100804 · ExternalCitation · doi-reference
Quantitative lipidomics in green robusta coffees from the Brazilian Amazon by LC-HRMS
10.1016/j.fbio.2023.103472 · ExternalCitation · doi-reference
Food grade extraction of Chlorella vulgaris polar lipids: A comparative lipidomic study
10.1016/j.foodchem.2021.131685 · ExternalCitation · doi-reference
Lipidomic characterization of polar and non-polar lipids in egg yolk and their anti-inflammatory and analgesic activities in zebrafish
10.1016/j.foodchem.2025.142855 · ExternalCitation · doi-reference
Mechanistic insights into aroma enhancement of Robusta coffee through ultrasound synergistic oil-solvent pretreatment: A combined lipidomics and volatilomics approach
10.1016/j.foodchem.2025.146134 · ExternalCitation · doi-reference
Quantitative lipidomics reveals the effects of roasting degree on Arabica coffee beans lipid profiles
10.1016/j.foodcont.2024.111015 · ExternalCitation · doi-reference
Comprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
10.1016/j.foodres.2020.109727 · ExternalCitation · doi-reference
Revealing the dynamic changes of lipids in coffee beans during roasting based on UHPLC-QE-HR-AM/MS/MS
10.1016/j.foodres.2023.113507 · ExternalCitation · doi-reference
Lipidomics insight on differences in lipid profiles and phytosterol compositions of coconut oils extracted by classical and green solvents
10.1016/j.foodres.2023.113653 · ExternalCitation · doi-reference
Tailored recovery of antioxidant fractions enriched in caffeine and phenolic compounds from coffee pulp using ethanol-modified supercritical carbon dioxide
10.1016/j.foodres.2024.115433 · ExternalCitation · doi-reference
Supercritical carbon dioxide and ethanol-assisted extraction of bioactive compounds from Bourbon, Catimor, and Caturra coffee pulp for maximized antioxidant and therapeutic properties
10.1016/j.fufo.2024.100381 · ExternalCitation · doi-reference
Enhanced extraction of spent coffee grounds oil using high-pressure CO2 plus ethanol solvents
10.1016/j.indcrop.2019.111723 · ExternalCitation · doi-reference
Lipid characterization of Arabica and Robusta coffee beans by liquid chromatography-ion mobility-mass spectrometry
10.1016/j.jfca.2022.104587 · ExternalCitation · doi-reference
Potential of microalgal lipids to prevent intestinal barrier disruption: A case study exploring the response of Caco-2 cells to the food contaminant deoxynivalenol
10.1016/j.jff.2025.107125 · ExternalCitation · doi-reference
Effects of ultra-high pressure processing on microstructure, water distribution and lipidomics variances of Arabica coffee beans
10.1016/j.lwt.2024.116784 · ExternalCitation · doi-reference
Lipidomics reveals the effects of various processing parameters on the lipid composition and activity of roasted coffee oil
10.1016/j.lwt.2024.116938 · ExternalCitation · doi-reference
Supercritical CO2 extraction of lipids from coffee silverskin: From laboratory optimization to industrial scale-up
10.1016/j.scp.2025.102001 · ExternalCitation · doi-reference
Supercritical fluid extraction to obtain ceramides from wool fibers
10.1016/j.seppur.2008.06.014 · ExternalCitation · doi-reference
Supercritical CO2 extraction of spent coffee grounds. Influence of co-solvents and characterization of the extracts
10.1016/j.supflu.2020.104825 · ExternalCitation · doi-reference
Neuroprotective properties of coffee: An update
10.1016/j.tifs.2021.04.052 · ExternalCitation · doi-reference
A simple method for the isolation and purification of total lipides from animal tissues
10.1016/s0021-9258(18)64849-5 · ExternalCitation · doi-reference
Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects
10.1017/s0007114512005338 · ExternalCitation · doi-reference
CLAW-MRM: Comprehensive lipidomics automation workflow for multiple reaction monitoring using large language models
10.1021/acs.analchem.4c05039 · ExternalCitation · doi-reference
Dietary bioactive lipids: A review on absorption, metabolism, and health properties
10.1021/acs.jafc.1c01369 · ExternalCitation · doi-reference
Lipophilic and hydrophilic metabolites as descriptors of different coffee beverages
10.1021/acs.jafc.4c03347 · ExternalCitation · doi-reference
pkCSM: Predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
10.1021/acs.jmedchem.5b00104 · ExternalCitation · doi-reference
Effect of the roast level on lipophilic and hydrophilic compounds in pot and filter coffee beverages
10.1021/acsfoodscitech.5c00066 · ExternalCitation · doi-reference
INFOGEST static in vitro simulation of gastrointestinal food digestion
10.1038/s41596-018-0119-1 · ExternalCitation · doi-reference
Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
10.1038/s44321-025-00349-6 · ExternalCitation · doi-reference
Gut–brain communication mediates the impact of dietary lipids on cognitive capacity
10.1039/d3fo05288e · ExternalCitation · doi-reference
Intestinal oxidative stress mitigation and transepithelial anti-inflammatory bioactivity mediated by EtOH-modified supercritical-CO2 coffee pulp extract
10.1039/d6fo00489j · ExternalCitation · doi-reference
Lipids as biomarkers of brain disorders
10.1080/10408398.2018.1529653 · ExternalCitation · doi-reference
Interactions of dietary polyphenols with epithelial lipids: Advances from membrane and cell models in the study of polyphenol absorption, transport and delivery to the epithelium
10.1080/10408398.2020.1791794 · ExternalCitation · doi-reference
Bioavailability and bioaccessibility of food bioactive compounds; overview and assessment by in vitro methods
10.1111/1541-4337.12623 · ExternalCitation · doi-reference
Brain lipidomics: From functional landscape to clinical significance
10.1126/sciadv.adc9317 · ExternalCitation · doi-reference
Applications of the INFOGEST in vitro digestion model to foods: A review
10.1146/annurev-food-060721-012235 · ExternalCitation · doi-reference
PI3K/Akt and ERK1/2 signalling are involved in quercetin-mediated neuroprotection against copper-induced injury
10.1155/2020/9834742 · ExternalCitation · doi-reference
Nootropic foods in neurodegenerative diseases: Mechanisms, challenges, and future
10.1186/s40035-025-00476-7 · ExternalCitation · doi-reference
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets
10.1371/journal.pbio.3003349 · ExternalCitation · doi-reference
Lipidomic alterations in the cerebral cortex and white matter in sporadic Alzheimer’s disease
10.14336/ad.2023.0217 · ExternalCitation · doi-reference
Insights into the role of copper in neurodegenerative diseases and the therapeutic potential of natural compounds
10.2174/1570159x22666231103085859 · ExternalCitation · doi-reference
Metabolic effects of gastric bypass surgery: Is it all about calories?
10.2337/db20-0131 · ExternalCitation · doi-reference
Ether lipid-mediated antioxidant defense in Alzheimer's disease
10.3390/antiox12020293 · ExternalCitation · doi-reference
Coffee oil extraction methods: A review
10.3390/foods13162601 · ExternalCitation · doi-reference
Unveiling the nutritional profile and safety of coffee pulp as a first step in its valorization strategy
10.3390/foods13183006 · ExternalCitation · doi-reference
Comparative characterization of lipid composition and minor components in coffee oils from Arabica and Robusta spent coffee grounds
10.3390/foods15122129 · ExternalCitation · doi-reference
Caffeine inhibits acetylcholinesterase, but not butyrylcholinesterase
10.3390/ijms14059873 · ExternalCitation · doi-reference
Phospholipid and lipid derivatives as potential neuroprotective compounds
10.3390/molecules23092257 · ExternalCitation · doi-reference
Coffee pulp, a by-product of coffee production, modulates gut microbiota and improves metabolic syndrome in high-carbohydrate, high-fat diet-fed rats
10.3390/pathogens10111369 · ExternalCitation · doi-reference
