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References from MINOS1-mediated mitochondrial remodeling: A critical regulator of apoptosis in hypoxic intestinal epithelium. Local targets link to admitted publications; unresolved targets remain external evidence.
Oxygen metabolism and barrier regulation in the intestinal mucosa
10.1172/jci84429 · 2016 · External reference
The intestinal barrier: a pivotal role in health, inflammation, and cancer
10.1016/s2468-1253(24)00390-x · 2025 · External reference
Hypoxia: an alarm signal during intestinal inflammation
10.1038/nrgastro.2010.39 · 2010 · External reference
High-altitude exposures and intestinal barrier dysfunction
10.1152/ajpregu.00270.2021 · 2022 · External reference
Life and death at the mucosal-luminal interface: new perspectives on human intestinal ischemia-reperfusion
10.3748/wjg.v22.i9.2760 · 2016 · External reference
Regulation of immunity and inflammation by hypoxia in immunological niches
10.1038/nri.2017.103 · 2017 · External reference
Hypoxia, hypoxia-inducible factors and inflammatory bowel diseases
2024 · External reference
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway
10.1038/s41419-021-03896-1 · 2021 · External reference
Intestinal permeability--a new target for disease prevention and therapy
10.1186/s12876-014-0189-7 · 2014 · External reference
The mechanism of Colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment
10.3389/fphys.2022.933659 · 2022 · External reference
High-altitude hypoxia promotes BRD4-mediated activation of the Wnt/β-catenin pathway and disruption of intestinal barrier
10.1016/j.cellsig.2024.111187 · 2024 · External reference
From mechanisms to therapeutics: molecular insights into gastrointestinal injury under high-altitude hypoxia
2026 · External reference
High-altitude hypoxia injury: systemic mechanisms and intervention strategies on immune and inflammatory responses
10.3390/antiox15010036 · 2025 · External reference
Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A review in the theme: cellular responses to hypoxia
10.1152/ajpcell.00191.2015 · 2015 · External reference
Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells
10.1186/1756-9966-31-28 · 2012 · External reference
Mitochondrial composition and function under the control of hypoxia
10.1016/j.redox.2017.02.012 · 2017 · External reference
Oxidative stress, mitochondrial permeability transition pore opening and cell death during hypoxia-reoxygenation in adult cardiomyocytes
10.1016/j.ejphar.2011.11.036 · 2012 · External reference
The use of cobalt chloride as a chemical hypoxia model
10.1002/jat.3749 · 2019 · External reference
Control and dysregulation of redox signalling in the gastrointestinal tract
10.1038/s41575-018-0079-5 · 2019 · External reference
Physiological roles of mitochondrial reactive oxygen species
10.1016/j.molcel.2012.09.025 · 2012 · External reference
10.1021/acsomega.9b01474 · 2019 · Admitted local publication
Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis
2025 · External reference
Effect of vitamin e supplementation on intestinal barrier function in rats exposed to high altitude hypoxia environment
10.4196/kjpp.2014.18.4.313 · 2014 · External reference
Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy
10.1038/s41418-024-01260-2 · 2024 · External reference
Ca(2+)-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak
10.1038/s41418-022-01025-9 · 2022 · External reference
Role of MINOS in mitochondrial membrane architecture and biogenesis
10.1016/j.tcb.2012.01.004 · 2012 · External reference
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization
10.1091/mbc.e11-09-0774 · 2012 · External reference
Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains
10.1016/j.jmb.2012.05.004 · 2012 · External reference
Genetic screen for cell fitness in high or low oxygen highlights mitochondrial and lipid metabolism
10.1016/j.cell.2020.03.029 · 2020 · External reference
Effects of high-altitude hypoxic environment on colonic inflammation, intestinal barrier and gut microbiota in three-way crossbred commercial pigs
10.3389/fmicb.2022.968521 · 2022 · External reference
Hypoxia inducible factor pathway proteins in high-altitude mammals
10.1016/j.tibs.2023.11.002 · 2024 · External reference
Unresolved reference
External reference
Loss-of-Function genetic screening identifies aldolase A as an essential driver for liver cancer cell growth under hypoxia
10.1002/hep.31846 · 2021 · External reference
Inhibition of the mPTP and lipid peroxidation is additively protective against I/R injury
10.1161/circresaha.123.323882 · 2024 · External reference
Mechanisms of cytochrome c release from mitochondria
10.1038/sj.cdd.4401950 · 2006 · External reference
Effects of acute exposure to hypobaric hypoxia on mucosal barrier injury and the gastrointestinal immune axis in rats
10.1089/ham.2018.0031 · 2019 · External reference
Establishment and evaluation of an experimental rat model for high-altitude intestinal barrier injury
10.3892/etm.2016.4012 · 2017 · External reference
Ancient homology of the mitochondrial contact site and cristae organizing system points to an endosymbiotic origin of mitochondrial cristae
10.1016/j.cub.2015.04.006 · 2015 · External reference
Role of hypoxia-induced bax translocation and cytochrome c release in reoxygenation injury
10.1038/sj.onc.1202590 · 1998 · External reference
Hypoxia-mediated programmed cell death is involved in the formation of wooden breast in broilers
10.1186/s40104-024-01036-1 · 2024 · External reference
Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress
10.7554/elife.52291 · 2020 · External reference
Caspases and kinases in a death grip
10.1016/j.cell.2009.08.021 · 2009 · External reference
Advances in pathogenesis and treatment of vascular endothelial injury-related diseases mediated by mitochondrial abnormality
2024 · External reference
Emerging insights into the pathogenesis and therapeutic strategies for vascular endothelial injury-associated diseases: focus on mitochondrial dysfunction
2024 · External reference
A novel ligustrazine-based nanodelivery system protects against doxorubicin-induced cardiotoxicity by targeting the SIRT5–DUSP1 axis for mitochondrial repair
2025 · External reference
Ginsenoside Rb1 attenuates coronary microvascular inflammatory injury via NDUFS4-SIRT5-DUSP1-mediated mitochondrial quality control in a murine ischemia-reperfusion model
2025 · External reference
Astragaloside VI attenuates mechanical stress-induced cardiac remodeling through piezo1-VDAC1 dependent endoplasmic reticulum unfolded protein response
2025 · External reference
Ligustrazine nano-drug delivery system ameliorates doxorubicin-mediated myocardial injury via piezo-type mechanosensitive ion channel component 1-prohibitin 2-mediated mitochondrial quality surveillance
2025 · External reference
Nuclear receptor subfamily 4 group A member 1 promotes myocardial ischemia/reperfusion injury through inducing mitochondrial fission factor-mediated mitochondrial fragmentation and inhibiting FUN14 domain containing 1-depedent mitophagy
2024 · External reference
Targeting mitochondria by lipid-selenium conjugate drug results in malate/fumarate exhaustion and induces mitophagy-mediated necroptosis suppression
2024 · External reference
DNA-PKcs-Driven YAP1 phosphorylation and nuclear translocation: a key regulator of ferroptosis in hyperglycemia-induced cardiac dysfunction in type 1 diabetes
2024 · External reference
Genome-wide CRISPR/Cas9 deletion screen defines mitochondrial gene essentiality and identifies routes for tumour cell viability in hypoxia
10.1038/s42003-021-02098-x · 2021 · External reference
Matrine attenuating cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity through improved mitochondrial membrane potential and activation of mitochondrial respiratory chain complex I pathway
10.1016/j.biopha.2024.116464 · 2024 · External reference
The mechanism of bound hydroxyl radical formation and degradation pathway of acid Orange II in Fenton-like Co2+-HCO3− system
10.1016/j.apcata.2013.09.045 · 2014 · External reference
Tanshinone IIA modulates Sirt5 and Metll3 interaction to govern mitochondria-endoplasmic reticulum unfolded protein response in coronary microvascular injury
2025 · External reference
Potential candidates of natural antioxidants from herbs for treating lung disorders: focus on redox balance and natural products
2025 · External reference
Potential of natural drug modulation of endoplasmic reticulum stress in the treatment of myocardial injury
2024 · External reference
Mitochondria and cell death: outer membrane permeabilization and beyond
10.1038/nrm2952 · 2010 · External reference
Cytochrome c: functions beyond respiration
10.1038/nrm2434 · 2008 · External reference
Mitochondrial membrane permeabilization in cell death
10.1152/physrev.00013.2006 · 2007 · External reference
Control of mitochondrial remodeling by the ATPase inhibitory factor 1 unveils a pro-survival relay via OPA1
10.1016/j.celrep.2017.01.070 · 2017 · External reference
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
10.1074/jbc.c200677200 · 2003 · External reference
Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis
10.1016/j.molcel.2014.10.028 · 2015 · External reference
The effect of unhealthy lifestyle on the pathogenesis of sick sinus syndrome A life-guiding review
2024 · External reference
Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis
2025 · External reference
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia
10.1016/j.cell.2013.04.048 · 2013 · External reference