References

The last decade of air pollution. epidemiology and the challenges of quantitative risk assessment

10.1186/s12940-024-01136-5 · 2024 · External reference

Impact of air pollution on the burden of. chronic respiratory diseases in China: time for urgent action

10.1016/s0140-6736(16)31597-5 · 2016 · External reference

PM2.5 increases susceptibility to acute exacerbation of. COPD via NOX4/Nrf2 redox imbalance-mediated mitophagy

10.1016/j.redox.2022.102587 · 2023 · External reference

New insight into air pollution-related cardiovascular. disease: an adverse outcome pathway framework of PM2.5-associated vascular calcification

10.1093/cvr/cvae082 · 2024 · External reference

Long-term Exposure to Ambient PM2.5 and Its Components Associated With Diabetes: Evidence From a Large Population-Based Cohort From China

10.2337/dc22-1585 · 2023 · External reference

Neurotoxicity of the air-borne particles: From. molecular events to human diseases

10.1016/j.jhazmat.2023.131827 · 2023 · External reference

Ambient PM2.5 Exposure and Bone Homeostasis: Analysis of UK Biobank Data and Experimental Studies in Mice and in Vitro

10.1289/ehp11646 · 2023 · External reference

Outdoor air pollution exposure, bone mineral. density, osteoporosis, and osteoporotic fractures: A systematic review and meta-analysis

10.1016/j.scitotenv.2022.161117 · 2023 · External reference

Association of Ambient and Household. Air Pollution With Bone Mineral Content Among Adults in Peri-urban South India

10.1001/jamanetworkopen.2019.18504 · 2020 · External reference

Ambient PM(2.5) components might. exacerbate bone loss among middle-aged and elderly women: evidence from a population-based cross-sectional study

10.1007/s00420-024-02090-y · 2024 · External reference

PM(2.5). exposure inhibits osteoblast differentiation by increasing the ubiquitination and degradation of Smad4

10.1016/j.toxlet.2024.06.010 · 2024 · External reference

Magnetic Graphene Oxide Nanocomposites Boosts Craniomaxillofacial Bone Regeneration by Modulating circAars/miR-128-3p/SMAD5 Signaling Axis

10.2147/ijn.s454718 · 2024 · External reference

CD137 Regulates Bone Loss via the p53 Wnt/β-Catenin Signaling Pathways in Aged Mice

10.3389/fendo.2022.922501 · 2022 · External reference

Tobacco toxins induce osteoporosis through ferroptosis

10.1016/j.redox.2023.102922 · 2023 · External reference

Geraniin promotes. osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) via activating β-catenin: a comparative study between BMSCs from normal and osteoporotic rats

10.1007/s11418-018-1242-6 · 2019 · External reference

Immunomodulatory properties of bone marrow. mesenchymal stem cells

10.1007/s12038-020-00068-9 · 2020 · External reference

Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells

10.7150/thno.16637 · 2017 · External reference

A multi-omics. Mendelian randomization study identifies new therapeutic targets for alcohol use disorder and problem drinking

10.1038/s41562-024-02040-1 · 2025 · External reference

integrated with metabolomics reveals the effect of benzo[a]pyrene exposure on acute lung injury

10.1016/j.ecoenv.2024.117323 · 2024 · External reference

Transcriptome analysis identifies IL24 as an autophagy modulator in PM2.5 caused lung dysfunction

10.1016/j.ecoenv.2022.114039 · 2022 · External reference

Serum metabolomics. analysis of mice that received repeated airway exposure to a water-soluble PM2.5 extract

10.1016/j.ecoenv.2018.10.068 · 2019 · External reference

Prenatal and Early Life Exposure to Ambient Air Pollutants Is Associated with the Fecal Metabolome in the First Two Years of Life

10.1021/acs.est.4c02929 · 2024 · External reference

Transcriptomic, epigenomic, and spatial metabolomic cell profiling redefines regional human kidney anatomy

10.1016/j.cmet.2024.02.015 · 2024 · External reference

Spatial multimodal analysis of transcriptomes and metabolomes in tissues

10.1038/s41587-023-01937-y · 2024 · External reference

Unraveling the. impact of PFOA toxicity on Zostera marina using a multi-omics approach: Insights from growth, physiological, transcriptomic, and metabolomic signatures

10.1016/j.jhazmat.2024.137024 · 2025 · External reference

Multi-omics. reveals ferroptosis as a key mechanism in PM2.5-exacerbated periodontitis via gingival fibroblast damage

10.1016/j.envint.2026.110139 · 2026 · External reference

PM2.5 contributed to pulmonary epithelial senescence. and ferroptosis by regulating USP3-SIRT3-P53 axis

10.1016/j.freeradbiomed.2023.06.017 · 2023 · External reference

The effects of estrogen deficiency on cortical bone microporosity and mineralization

10.1016/j.bone.2018.01.019 · 2018 · External reference

An overview and management of osteoporosis

10.5152/eurjrheum.2016.048 · 2017 · External reference

Skeletal muscle-derived extracellular vesicles transport glycolytic enzymes to mediate muscle-to-bone crosstalk

10.1016/j.cmet.2023.10.013 · 2023 · External reference

WTAP-mediated. m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis

10.1038/s41419-023-05565-x · 2023 · External reference

Effects of. environmental air pollutants on CFTR expression and function in human airway epithelial cells

10.1016/j.tiv.2021.105253 · 2021 · External reference

A Novel PTH-Related Peptide Combined With 3D Printed Macroporous Titanium Alloy Scaffold Enhances Osteoporotic Osseointegration

10.1002/adhm.202301604 · 2023 · External reference

The combined effects of. nanotopography and Sr ion for enhanced osteogenic activity of bone marrow mesenchymal stem cells (BMSCs)

10.1177/0885328217692140 · 2017 · External reference

Effect. of magnetic graphene oxide on cellular behaviors and osteogenesis under a moderate static magnetic field

2021 · External reference

Circular RNA circSTX12 regulates osteo-adipogenic balance and proliferation of BMSCs in senile osteoporosis

10.1007/s00018-025-05684-y · 2025 · External reference

3D. printed polycaprolactone/beta-tricalcium phosphate/magnesium peroxide oxygen releasing scaffold enhances osteogenesis and implanted BMSCs survival in repairing the large bone defect

10.1039/d1tb00178g · 2021 · External reference

Extracellular vesicles from apoptotic BMSCs ameliorate osteoporosis via transporting regenerative signals

10.7150/thno.96174 · 2024 · External reference

Icariin Promotes the Migration. of BMSCs In Vitro and In Vivo via the MAPK Signaling Pathway

10.1155/2018/2562105 · 2018 · External reference

Role of N-Cadherin in a Niche-Mimicking. Microenvironment for Chondrogenesis of Mesenchymal Stem Cells In Vitro

10.1021/acsbiomaterials.0c00149 · 2020 · External reference

TGF-β1-induced bone marrow mesenchymal stem cells (BMSCs) migration via histone demethylase KDM6B mediated inhibition of methylation marker H3K27me3

10.1038/s41420-022-01132-z · 2022 · External reference

Integrin α4 is involved in the regulation of. glioma-induced motility of bone marrow mesenchymal stem cells

10.3892/or.2015.4012 · 2015 · External reference

PTH(1-34) activates the migration and. adhesion of BMSCs through the rictor/mTORC2 pathway

10.3892/ijmm.2020.4754 · 2020 · External reference

A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow

10.1182/blood-2004-02-0526 · 2004 · External reference

Mitochondria from osteolineage cells regulate myeloid cell-mediated bone resorption

10.1038/s41467-024-49159-3 · 2024 · External reference

Mitochondrial quality control. and its role in osteoporosis

2023 · External reference

Q10. Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway

10.1007/s00223-023-01161-5 · 2024 · External reference

Mitochondria-specific antioxidant MitoTEMPO. alleviates senescence of bone marrow mesenchymal stem cells in ovariectomized rats

10.1002/jcp.31323 · 2024 · External reference

The involvement of mitochondrial fission in maintenance. of the stemness of bone marrow mesenchymal stem cells

10.1177/1535370218821063 · 2019 · External reference

Dynamin-related protein 1. has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

10.1038/s41467-018-07543-w · 2018 · External reference

Mdivi-1 alleviates nicotine-induced human. periodontal ligament cells injury by inhibiting mitochondrial fission and dysfunction through the JNK/Drp1 pathway

10.1016/j.ecoenv.2024.117338 · 2024 · External reference

Drp1-dependent mitochondrial fission mediates. osteogenic dysfunction in inflammation through elevated production of reactive oxygen species

10.1371/journal.pone.0175262 · 2017 · External reference

Mitochondrial dynamics: overview of molecular. mechanisms

10.1042/ebc20170104 · 2018 · External reference

Estrogen promotes lncRNA H19 expression to regulate. osteogenic differentiation of BMSCs and reduce osteoporosis via miR-532-3p/SIRT1 axis

10.1016/j.mce.2021.111171 · 2021 · External reference

Lycium barbarum polysaccharide protects BMSCs against cadmium-induced suppression of osteogenic differentiation by modulating autophagy

10.1016/j.ecoenv.2025.118148 · 2025 · External reference

Chronic exposure to polystyrene. microplastics triggers osteoporosis by breaking the balance of osteoblast and osteoclast differentiation

10.1016/j.tox.2024.154017 · 2025 · External reference

Evaluation of the Effects of Airborne Particulate Matter on Bone Marrow-Mesenchymal Stem Cells (BM-MSCs): Cellular, Molecular and Systems Biological Approaches

10.3390/ijerph14040440 · 2017 · External reference

G-protein-coupled receptor 124 promotes osteogenic differentiation of. BMSCs through the Wnt/β-catenin pathway

10.1007/s11626-022-00684-9 · 2022 · External reference

Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2

10.3390/ijms20071694 · 2019 · External reference

bFGF-Loaded Mesoporous. Silica Nanoparticles Promote Bone Regeneration Through the Wnt/β-Catenin Signalling Pathway

10.2147/ijn.s366926 · 2022 · External reference

β-Catenin Limits Osteogenesis on Regenerative Materials in a Stiffness-Dependent Manner

10.1002/adhm.202101467 · 2021 · External reference

KLF2. regulates osteoblast differentiation by targeting of Runx2

10.1038/s41374-018-0149-x · 2019 · External reference

Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies

10.1159/000166277 · 2009 · External reference

Ca(2+)-stimulated adenylyl cyclases as therapeutic targets for. psychiatric and neurodevelopmental disorders

2022 · External reference

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate. signalling cross-talk, desensitization and compartmentalization

2003 · External reference

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

10.1038/24884 · 1998 · External reference

Transcriptional regulation by the phosphorylation-dependent factor CREB

10.1038/35085068 · 2001 · External reference

Anchored PKA synchronizes adrenergic phosphoregulation of cardiac Ca(v)1.2 channels

10.1016/j.jbc.2024.107656 · 2024 · External reference

Forskolin: unique diterpene activator of adenylate cyclase. in membranes and in intact cells

10.1073/pnas.78.6.3363 · 1981 · External reference

cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo

10.1073/pnas.0711190105 · 2008 · External reference

cAMP and mitochondria

2013 · External reference