References

Acute liver failure

10.1016/s0140-6736(24)00693-7 · 2024 · External reference

Acute Liver Failure Guidelines

10.14309/ajg.0000000000002340 · 2023 · External reference

Global, regional, and national burden of stroke and its risk factors, 1990-2021: a systematic analysis for the global Burden of Disease Study 2021

10.1016/s1474-4422(24)00369-7 · 2024 · External reference

Liver transplantation for fulminant hepatic failure: experience with more than 200 patients over a 17-year period

10.1097/01.sla.0000064365.54197.9e · 2003 · External reference

Acetylcorynoline alleviates acute liver injury via inhibiting TLR4/JNK/NF-ĸB pathway based on RNA-seq and molecular docking in vivo and in vitro

10.1016/j.intimp.2024.113550 · 2024 · External reference

Prevention of D-GalN/LPS-induced ALI by 18β-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation

10.1038/s41419-021-03768-8 · 2021 · External reference

Acute liver failure

10.1016/s0140-6736(19)31894-x · 2019 · External reference

Ultra-small quercetin-based nanotherapeutics ameliorate acute liver failure by combatting inflammation/cellular senescence cycle

10.7150/thno.103746 · 2025 · External reference

Endotoxic septic shock: diagnosis and treatment

10.3390/ijms242216185 · 2023 · External reference

Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice

10.1016/j.fct.2018.07.053 · 2018 · External reference

S100A9(-/-) alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFκB signaling axis

10.1016/j.biopha.2024.116233 · 2024 · External reference

Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux

10.1016/j.redox.2025.103557 · 2025 · External reference

The effects of galactosamine on UTP levels in the livers of young, adult and old rats

10.18388/abp.2000_4014 · 2000 · External reference

Luteolin detoxifies DEHP and prevents liver injury by degrading Uroc1 protein in mice

10.1038/s44321-024-00160-9 · 2024 · External reference

Framework and practice of network-based studies for Chinese herbal formula

10.3736/jcim20070501 · 2007 · External reference

Glycyrrhizic acid mitigates tripterygium-glycoside-tablet-induced acute liver injury via PKM2 regulated oxidative stress

10.3390/metabo12111128 · 2022 · External reference

Preclinical validation of silibinin/albumin nanoparticles as an applicable system against acute liver injury

10.1016/j.actbio.2022.04.021 · 2022 · External reference

Glycyrrhizic acid alleviates concanavalin a-induced acute liver injury by regulating monocyte-derived macrophages

10.1016/j.phymed.2024.155586 · 2024 · External reference

Silymarin protects against acute liver injury induced by acetaminophen by downregulating the expression and activity of the CYP2E1 enzyme

10.3390/molecules27248855 · 2022 · External reference

Oxysophocarpine attenuates inflammatory osteolysis by modulating the NF-κb pathway and the reactive oxygen species-related Nrf2 signaling pathway

10.1007/s10787-024-01552-6 · 2024 · External reference

Oxysophocarpine inhibits airway inflammation and mucus hypersecretion through JNK/AP-1 pathway in vivo and in vitro

10.1016/j.fitote.2022.105278 · 2022 · External reference

Oxysophocarpine suppresses TRAF6 level to ameliorate oxidative stress and inflammatory factors secretion in mice with dextran sulphate sodium (DSS) induced-ulcerative colitis

10.1016/j.micpath.2023.106244 · 2023 · External reference

Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties

10.1021/jm000942e · 2000 · External reference

Pharmacokinetics of actinoymcin D in patients with malignant melanoma

10.1002/cpt1975176701 · 1975 · External reference

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease

10.1016/j.jep.2012.09.051 · 2013 · External reference

Abrogation of MAPK and Akt signaling by AEE788 synergistically potentiates histone deacetylase inhibitor-induced apoptosis through reactive oxygen species generation

10.1158/1078-0432.ccr-06-1751 · 2007 · External reference

Association of reactive oxygen species levels and radioresistance in cancer stem cells

10.1038/nature07733 · 2009 · External reference

Target identification using drug affinity responsive target stability (DARTS)

10.1073/pnas.0910040106 · 2009 · External reference

Esculin inhibits hepatic stellate cell activation and CCl(4)-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway

10.1016/j.phymed.2024.155465 · 2024 · External reference

Structure-Based identification of a potent KDM7A inhibitor exerts anticancer activity through transcriptionally reducing MKRN1 in taxol- resistant and -sensitive triple-negative breast cancer cells

10.1016/j.bioorg.2024.107945 · 2024 · External reference

Marine staurosporine analogues: activity and target identification in triple-negative breast cancer

10.3390/md22100459 · 2024 · External reference

Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice

10.1002/hep.22284 · 2008 · External reference

Small molecule Pin 1 inhibitor blocking NF-κB signaling in prostate cancer cells

10.1002/asia.201701216 · 2018 · External reference

Evaluation on the antibacterial activity of glycyrrhizin against Pseudomonas plecoglossicida in ayu fish ( Plecoglossus altivelis)

2025 · External reference

Marine staurosporine analogues: activity and target identification in triple-negative breast cancer

10.3390/md22100459 · 2024 · External reference

Embelin mitigates the impact of perinatal inflammation on Neuron development by inhibiting 5-Lipoxygenase-Mediated ferroptosis

10.1002/ptr.70052 · 2025 · External reference

HDAC11 inhibition as a potential therapeutic strategy for AML: target identification, lead discovery, Antitumor potency, and mechanism investigation

10.1021/acs.jmedchem.4c02550 · 2025 · External reference

Perls/DAB staining to examine iron distribution in arabidopsis embryos

10.1007/978-1-0716-3183-6_13 · 2023 · External reference

Pectolinarigenin ameliorates acetaminophen-induced acute liver injury via attenuating oxidative stress and inflammatory response in Nrf2 and PPARa dependent manners

10.1016/j.phymed.2023.154726 · 2023 · External reference

Fructose-1,6-bisphosphatase 1 in cancer: dual roles, mechanistic insights, and therapeutic potential - a comprehensive review

10.1016/j.ijbiomac.2024.139273 · 2025 · External reference

PPARα alleviates iron overload-induced ferroptosis in mouse liver

10.15252/embr.202052280 · 2022 · External reference

ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis

10.1007/s00204-023-03476-6 · 2023 · External reference

Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1

10.1016/j.apsb.2021.12.007 · 2022 · External reference

Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death, and lipolysis

10.1016/j.jcmgh.2022.10.002 · 2023 · External reference

Neuroprotective effects of oxysophocarpine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion

10.3109/13880209.2013.877039 · 2014 · External reference

Thonningianin A ameliorates acetaminophen-induced liver injury by activating GPX4 and modulating endoplasmic reticulum stress

10.3389/fphar.2025.1531277 · 2025 · External reference

Deletion of TLR4 attenuates lipopolysaccharide-induced acute liver injury by inhibiting inflammation and apoptosis

10.1038/s41401-020-00597-x · 2021 · External reference

Apoptosis and necrosis in the liver: a tale of two deaths?

10.1002/hep.21062 · 2006 · External reference

LPS-induced apoptosis is dependent upon mitochondrial dysfunction

10.1023/b:appt.0000031453.90821.6a · 2004 · External reference

Apoptosis and necroptosis in the liver: a matter of life and death

10.1038/s41575-018-0065-y · 2018 · External reference

Liver transplantation for acute liver failure and acute-on-chronic liver failure

10.1016/j.ajt.2024.07.012 · 2024 · External reference

Med 1 inhibits ferroptosis and alleviates liver injury in acute liver failure via Nrf2 activation

10.1186/s13578-024-01234-4 · 2024 · External reference

Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth

10.1038/s41556-022-01009-4 · 2022 · External reference

Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness

10.1016/j.cmet.2023.03.021 · 2023 · External reference