Research graph
References from Microgravity induces morphological and molecular reprogramming in Atlantic Salmon (Salmo salar) kidney cell line. Local targets link to admitted publications; unresolved targets remain external evidence.
Fish cell spheroids, a promising in vitro model to mimic in vivo research: a review
10.3390/cells13211818 · 2024 · External reference
Recent applications of fish cell culture to biomedical research
10.1002/jez.1402480307 · 1988 · External reference
Beyond the petri dish: fish cell lines pioneering advances in biotechnology, genetic engineering, toxicity and disease solutions
10.1186/s44315-025-00022-0 · 2025 · External reference
The use of fish cell lines as in-vitro ecotoxicological tools: a cellular solution to aquaculture sustainability
10.1016/j.aquaculture.2024.741302 · 2024 · External reference
Role and relevance of fish cell lines in advanced in vitro research
10.1007/s11033-021-06997-4 · 2022 · External reference
Spheroid culture as a tool for creating 3D complex tissues
10.1016/j.tibtech.2012.12.003 · 2013 · External reference
Recent advances in three‐dimensional multicellular spheroid culture for biomedical research
10.1002/biot.200700228 · 2008 · External reference
Integrating novel technologies to fabricate smart scaffolds
10.1163/156856208784089571 · 2008 · External reference
Hydrogels in regenerative medicine
10.1002/adma.200802106 · 2009 · External reference
The fast rotating clinostat: a history of its use in gravitational biology and a comparison of ground-based and flight experiment results
1992 · External reference
3D cell culture model: from ground experiment to microgravity study
10.3389/fbioe.2023.1136583 · 2023 · External reference
Growing tissues in microgravity
10.1038/nm0898-901 · 1998 · External reference
Cellular mechanotransduction of human osteoblasts in microgravity
10.1038/s41526-024-00386-4 · 2024 · External reference
Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
10.3389/fcell.2022.841017 · 2022 · External reference
Cellular agriculture: opportunities and challenges
10.1146/annurev-food-063020-123940 · 2021 · External reference
Optimized suspension culture: the rotating-wall vessel
10.1152/ajprenal.2001.281.1.f12 · 2001 · External reference
An air bubble-isolating rotating wall vessel bioreactor for improved spheroid/organoid formation
10.1089/ten.tec.2019.0088 · 2019 · External reference
Comparison of three-dimensional cell culture techniques of dedifferentiated liposarcoma and their integration with future research
10.3389/fcell.2024.1362696 · 2024 · External reference
Development of 3D cultures of zebrafish liver and embryo cell lines: a comparison of different spheroid formation methods
10.1007/s10646-021-02459-6 · 2021 · External reference
Tissue engineering under microgravity conditions–use of stem cells and specialized cells
10.1089/scd.2017.0242 · 2018 · External reference
Cellular response in three-dimensional spheroids and tissues exposed to real and simulated microgravity: a narrative review
10.1038/s41526-024-00442-z · 2024 · External reference
3D microenvironment attenuates simulated microgravity-mediated changes in T cell transcriptome
10.1007/s00018-022-04531-8 · 2022 · External reference
Cultured meat: advances in stem cell biology, tissue engineering, and bioprocess optimisation for scalable and sustainable production—a review
10.1093/ijfood/vvaf220 · 2025 · External reference
Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways
10.1038/s41598-018-20459-1 · 2018 · External reference
Effect of simulated microgravity on metabolism of HGC-27 gastric cancer cells
2020 · External reference
Effects of temperature on feeding and digestive processes in fish
10.1080/23328940.2020.1765950 · 2020 · External reference
Impacts of low temperature on the teleost immune system
10.3390/biology6040039 · 2017 · External reference
Anatomy of teleost fish immune structures and organs
2022 · External reference
Cell-based fish: a novel approach to seafood production and an opportunity for cellular agriculture
10.3389/fsufs.2019.00043 · 2019 · External reference
A global comprehensive review on cultured seafood
10.1038/s41538-025-00461-4 · 2025 · External reference
Technical, commercial, and regulatory challenges of cellular agriculture for seafood production
10.1016/j.tifs.2024.104341 · 2024 · External reference
The challenges of using fish cells for cultivated seafood production
10.1007/s10068-024-01786-8 · 2025 · External reference
Atlantic salmon cardiac primary cultures: an in vitro model to study viral host pathogen interactions and pathogenesis
10.1371/journal.pone.0181058 · 2017 · External reference
Unresolved reference
2012 · External reference
Local knowledge, social identity and conflicts around traditional marine salmon fisheries–A case from mid‐Norway
10.1111/fme.12522 · 2022 · External reference
FAO the state of world fisheries and aquaculture
2020 · External reference
Xenobiotic metabolizing enzyme activities in aggregate culture of rainbow trout hepatocytes
10.1016/0141-1136(94)00027-m · 1995 · External reference
Maintenance of cytochrome P450 content and phase I and phase II enzyme activities in trout hepatocytes cultured as spheroidal aggregates
10.1016/0742-8413(95)02093-4 · 1996 · External reference
Towards a more representative in vitro method for fish ecotoxicology: morphological and biochemical characterisation of three-dimensional spheroidal hepatocytes
10.1007/s10646-012-0965-5 · 2012 · External reference
Performance of three‐dimensional rainbow trout (Oncorhynchus mykiss) hepatocyte spheroids for evaluating biotransformation of pyrene
10.1002/etc.4476 · 2019 · External reference
Functional xenobiotic metabolism and efflux transporters in trout hepatocyte spheroid cultures
10.1039/c4tx00160e · 2015 · External reference
Development of a 3D spheroid cell culture system from fish cell lines for in vitro infection studies: evaluation with Saprolegnia parasitica
10.1111/jfd.13331 · 2021 · External reference
In vitro toxicity of glyphosate in Atlantic salmon evaluated with a 3D hepatocyte-kidney co-culture model
10.1016/j.fct.2022.113012 · 2022 · External reference
Development of three-dimensional (3D) spheroid culture system from rainbow trout kidney cell line (RTK) for in vitro production of fish viral pathogen
10.1007/s10499-024-01414-6 · 2024 · External reference
Immune transcriptional response in head kidney primary cell cultures isolated from the three most important species in Chilean salmonids aquaculture
10.3390/biology12070924 · 2023 · External reference
Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on 1H NMR
10.1016/j.fsi.2016.08.055 · 2016 · External reference
Ion transporters and osmoregulation in the kidney of teleost fishes as a function of salinity
10.3389/fphys.2021.664588 · 2021 · External reference
Fish hepatocyte spheroids–A powerful (though underexplored) alternative in vitro model to study hepatotoxicity
10.1016/j.cbpc.2022.109470 · 2022 · External reference
Renibacterium salmoninarum iron‐acquisition mechanisms and ASK cell line infection: virulence and immune response
10.1111/jfd.13051 · 2019 · External reference
Culturing and applications of rotating wall vessel bioreactor derived 3D epithelial cell models
2012 · External reference
Structural and molecular changes of human chondrocytes exposed to the rotating wall vessel bioreactor
10.3390/biom14010025 · 2023 · External reference
Three-dimensional rotating wall vessel-derived cell culture models for studying virus-host interactions
10.3390/v8110304 · 2016 · External reference
Haemato-Immunological response of immunized Atlantic salmon (Salmo salar) to Moritella viscosa challenge and antigens
10.3390/vaccines12010070 · 2024 · External reference
A formaldehyde glutaraldehyde fixative of high osmolality for use in electron microscopy
1965 · External reference
Aeromonas salmonicida infects Atlantic salmon (Salmo salar) erythrocytes
10.1111/jfd.13077 · 2019 · External reference
Flow cytometry in clinical pathology
10.1258/acb.2011.011128 · 2012 · External reference
A novel marine pathogen isolated from wild cunners (Tautogolabrus adspersus): comparative genomics and transcriptome profiling of Pseudomonas sp. strain J380
10.3390/microorganisms9040812 · 2021 · External reference
RNA-seq gene expression estimation with read mapping uncertainty
10.1093/bioinformatics/btp692 · 2010 · External reference
A benchmark for RNA-seq quantification pipelines
10.1186/s13059-016-0940-1 · 2016 · External reference
Comparison of normalization methods for the analysis of metagenomic gene abundance data
10.1186/s12864-018-4637-6 · 2018 · External reference
edgeR: a bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
Cytoscape: a software environment for integrated models of biomolecular interaction networks
10.1101/gr.1239303 · 2003 · External reference
ClueGO: a cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
10.1093/bioinformatics/btp101 · 2009 · External reference
CluePedia cytoscape plugin: pathway insights using integrated experimental and in silico data
10.1093/bioinformatics/btt019 · 2013 · External reference
The dietary replacement of marine ingredients by terrestrial animal and plant alternatives modulates the antiviral immune response of Atlantic salmon (Salmo salar)
10.1016/j.fsi.2017.02.040 · 2017 · External reference
Primer3—new capabilities and interfaces
10.1093/nar/gks596 · 2012 · External reference
Primer3_masker: integrating masking of template sequence with primer design software
10.1093/bioinformatics/bty036 · 2018 · External reference
Enhancements and modifications of primer design program Primer3
10.1093/bioinformatics/btm091 · 2007 · External reference
A new mathematical model for relative quantification in real-time RT–PCR
10.1093/nar/29.9.e45 · 2001 · External reference
10.1186/gb-2002-3-7-research0034 · 2002 · Admitted local publication
Unresolved reference
2009 · External reference
SGLT1/2 as the potential biomarkers of renal damage under Apoe−/− and chronic stress via the BP neural network model and support vector machine
10.3389/fcvm.2022.948909 · 2022 · External reference
Benchmarking of RNA-sequencing analysis workflows using whole-transcriptome RT-qPCR expression data
10.1038/s41598-017-01617-3 · 2017 · External reference
Transcriptome profiling of lumpfish (Cyclopterus lumpus) head kidney to Renibacterium salmoninarum at early and chronic infection stages
10.1016/j.dci.2024.105165 · 2024 · External reference
Quantitative evaluation of the site-dependent cell viability in three-dimensional hepatocyte spheroids based on dynamic optical coherence tomography
10.1117/1.jbo.30.3.035003 · 2025 · External reference
Establishing brown trout primary hepatocyte spheroids as a new alternative experimental model—Testing the effects of 5α-dihydrotestosterone on lipid pathways
10.1016/j.aquatox.2022.106331 · 2022 · External reference
A step forward in the characterization of primary brown trout hepatocytic spheroids as experimental models
10.3390/ani13142277 · 2023 · External reference
Estrogenic responsiveness of brown trout primary hepatocyte spheroids to environmental levels of 17α-Ethinylestradiol
10.3390/jox14030060 · 2024 · External reference
Transcriptomic and physiological analysis of endocrine disrupting chemicals impacts on 3D Zebrafish liver cell culture system
10.1016/j.aquatox.2022.106105 · 2022 · External reference
Development of three-dimensional (3D) spheroid cultures of the continuous rainbow trout liver cell line RTL-W1
10.1016/j.ecoenv.2018.10.009 · 2019 · External reference
Lympho-hematopoietic microenvironments and fish immune system
10.3390/biology11050747 · 2022 · External reference
Melanogenesis in visceral tissues of Salmo salar. A link between immunity and pigment production?
10.1139/o2012-033 · 2012 · External reference
A multidisciplinary study of the extracutaneous pigment system of European sea bass (Dicentrarchus labrax L.). A possible relationship between kidney disease and dopa oxidase activity level
10.1016/j.fsi.2014.10.031 · 2015 · External reference
Microgravity and cellular biology: insights into cellular responses and implications for human health
10.3390/ijms26073058 · 2025 · External reference
Simulated microgravity condition alters the gene expression of some ECM and adhesion molecules in adipose derived stem cells
2018 · External reference
The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells
10.1002/sctm.20-0084 · 2020 · External reference
Modeling the impact of microgravity at the cellular level: implications for human disease
10.3389/fcell.2020.00096 · 2020 · External reference
Simulated microgravity inhibits the proliferation of chang liver cells by attenuation of the major cell cycle regulators and cytoskeletal proteins
10.3390/ijms22094550 · 2021 · External reference
Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells
10.1038/s41526-023-00339-3 · 2023 · External reference
Genome wide expression profiling of cancer cell lines cultured in microgravity reveals significant dysregulation of cell cycle and MicroRNA gene networks
10.1371/journal.pone.0135958 · 2015 · External reference
Simulated microgravity induces DNA damage concurrent with impairment of DNA repair and activation of cell-type specific DNA damage response in microglial and glioblastoma cells
10.1016/j.bbamcr.2024.119679 · 2024 · External reference
Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes
10.1002/jcb.22171 · 2009 · External reference
Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing
10.1371/journal.pone.0022214 · 2011 · External reference
A microRNA signature and TGF-β1 response were identified as the key master regulators for spaceflight response
10.1371/journal.pone.0199621 · 2018 · External reference
Simulated microgravity reduces focal adhesions and alters cytoskeleton and nuclear positioning leading to enhanced apoptosis via suppressing FAK/RhoA-mediated mTORC1/NF-κB and ERK1/2 pathways
10.3390/ijms19071994 · 2018 · External reference
Simulated microgravity significantly altered metabolism in epidermal stem cells
10.1007/s11626-020-00435-8 · 2020 · External reference
Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis
10.1007/s00018-022-04243-z · 2022 · External reference
Extracellular matrix-cell interactions: focus on therapeutic applications
10.1016/j.cellsig.2019.109487 · 2020 · External reference
Electron-microscopic study of innervation of smooth muscle cells surrounding collecting tubules of the fish kidney
10.1007/bf00217302 · 1984 · External reference
The melano-macrophage: the black leukocyte of fish immunity
10.1016/j.fsi.2024.109523 · 2024 · External reference
The role of peroxisome proliferator-activated receptors (PPAR) in immune responses
10.1016/j.metabol.2020.154338 · 2021 · External reference
Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation
10.1038/s41598-019-51410-7 · 2019 · External reference
TRPML1 ion channel promotes HepaRG cell differentiation under simulated microgravity conditions
10.1038/s41526-025-00461-4 · 2025 · External reference
Melanosomes—Dark organelles enlighten endosomal membrane transport
10.1038/nrm2258 · 2007 · External reference
