Research graph
References from A teleost - Specific Sema4E - like protein promotes grass carp reovirus infection by upregulating HSP70 expression. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2024 · External reference
Maintenance of fish health in aquaculture: review of epidemiological approaches for prevention and control of infectious disease of fish
10.1155/2018/5432497 · 2018 · External reference
Emerging viruses in aquaculture
10.1016/j.coviro.2018.12.008 · 2019 · External reference
Grass carp reovirus encoding circular RNAs with antiviral activity
10.1016/j.aquaculture.2020.736135 · 2021 · External reference
Insights into the antiviral immunity against grass carp ( Ctenopharyngodon idella ) reovirus (GCRV) in grass carp
10.1155/2015/670437 · 2015 · External reference
Immunotherapies targeting fish mucosal immunity – current knowledge and future perspectives
10.3389/fimmu.2015.00643 · 2016 · External reference
The antiviral innate immune response in fish: evolution and conservation of the IFN system
10.1016/j.jmb.2013.09.033 · 2013 · External reference
Grass carp reovirus (GCRV) giving its all to suppress IFN production by countering MAVS signaling transduction
10.3389/fimmu.2020.545302 · 2020 · External reference
Grass carp reovirus VP56 allies VP4, recruits, blocks, and degrades RIG-I to more effectively attenuate IFN responses and facilitate viral evasion
10.1128/spectrum.01000-21 · 2021 · External reference
Reticulon 4a facilitates grass carp reovirus replication by integrating membrane remodeling and viral protein recruitment via its reticulon homology domain
10.1016/j.fsi.2025.111036 · 2026 · External reference
Cyprinid-specific duplicated membrane TLR5 senses dsRNA as functional homodimeric receptors
10.15252/embr.202154281 · 2022 · External reference
The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules
10.1016/0092-8674(93)90625-z · 1993 · External reference
Immunological functions of the neuropilins and plexins as receptors for semaphorins
10.1038/nri3545 · 2013 · External reference
Semaphorins in immune cell function, inflammatory and infectious diseases
10.1016/j.crimmu.2023.100060 · 2023 · External reference
Unresolved reference
2015 · External reference
Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation
10.1073/pnas.93.21.11780 · 1996 · External reference
Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis
10.1073/pnas.0508825103 · 2006 · External reference
Class IV semaphorin Sema4A enhances T-cell activation and interacts with tim-2
10.1038/nature01037 · 2002 · External reference
Zebrafish hox clusters and vertebrate genome evolution
10.1126/science.282.5394.1711 · 1998 · External reference
Semaphorin/neuropilin binding specificities are stable over 400 million years of evolution
10.1016/j.bbrc.2019.06.133 · 2019 · External reference
Transmembrane Sema4E guides branchiomotor axons to their targets in zebrafish
10.1523/jneurosci.23-10-04190.2003 · 2003 · External reference
Semaphorins and their receptors in immune cell interactions
10.1038/ni1553 · 2008 · External reference
NS38 is required for aquareovirus replication via interaction with viral core proteins and host eIF3A
10.1016/j.virol.2019.01.029 · 2019 · External reference
An aquareovirus exploits membrane-anchored HSP70 to promote viral entry
10.1128/spectrum.04055-22 · 2023 · External reference
Aquareovirus NS80 initiates efficient viral replication by retaining core proteins within replication-associated viral inclusion bodies
2015 · External reference
Targeting heat shock protein 70 as an antiviral strategy against grass carp reovirus infection
10.1016/j.virusres.2018.01.005 · 2018 · External reference
Mitogen-activated protein kinases in innate immunity
10.1038/nri3495 · 2013 · External reference
p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
10.1016/j.canlet.2013.11.019 · 2014 · External reference
Axon guidance: semaphorin/neuropilin/plexin signaling
2020 · External reference
Semaphorins in interactions between T cells and antigen-presenting cells
10.1038/nri1003 · 2003 · External reference
miR-2188-5p promotes GCRV replication by the targeted degradation of klf2a in ctenopharyngodon idellus
10.1016/j.dci.2022.104516 · 2023 · External reference
From 2R to 3R: evidence for a fish-specific genome duplication (FSGD)
10.1002/bies.20293 · 2005 · External reference
The medaka draft genome and insights into vertebrate genome evolution
10.1038/nature05846 · 2007 · External reference
Isolation, identification, and genomic analysis of a novel reovirus from healthy grass carp and its dynamic proliferation in vitro and in vivo
10.3390/v13040690 · 2021 · External reference
Analysis of GCRV pathogenesis and therapeutic measures through proteomic and metabolomic investigations in GCRV-infected tissues of grass carp (ctenopharyngodon idella)
10.3390/ijms252111852 · 2024 · External reference
Identification and characterization of a novel reovirus strain isolated fromgrass carp (ctenopharyngodon idella)
10.1186/s12985-025-02716-8 · 2025 · External reference
Class IV semaphorins promote angiogenesis by stimulating rho-initiated pathways through plexin-B
10.1158/0008-5472.can-04-0126 · 2004 · External reference
Signalling and crosstalk of rho GTPases in mediating axon guidance
10.1038/ncb895 · 2003 · External reference
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology
10.1016/s0896-6273(02)00750-x · 2002 · External reference
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
10.1152/physrev.2001.81.2.807 · 2001 · External reference
Chapter 9 viral strategies to subvert the mammalian translation machinery
2009 · External reference
Emerging translation strategies during virus–host interaction
10.1002/wrna.1619 · 2021 · External reference
Regulation of translation initiation in eukaryotes: mechanisms and biological targets
10.1016/j.cell.2009.01.042 · 2009 · External reference
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
10.1038/sj.onc.1210412 · 2007 · External reference
Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
10.1016/j.ccr.2012.06.031 · 2012 · External reference
Heat shock factors: integrators of cell stress, development and lifespan
10.1038/nrm2938 · 2010 · External reference
Heat shock protein 70 kDa molecular biology, biochemistry, and physiology
10.1016/s0163-7258(98)00028-x · 1998 · External reference
Hsp70 chaperones: cellular functions and molecular mechanism
10.1007/s00018-004-4464-6 · 2005 · External reference
Heat shock proteins and virus replication: hsp70s as mediators of the antiviral effects of prostaglandins
10.1007/bf01923459 · 1994 · External reference
