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References from Involvement of LTC4 and NADPH oxidase 5 in extracellular trap formation in Ruditapes philippinarum. Local targets link to admitted publications; unresolved targets remain external evidence.
Ruditapes philippinarum and Ruditapes decussatus under Hg environmental contamination
10.1007/s11356-015-4397-7 · 2015 · External reference
Immune priming reshapes the microbiota and modulates pathogen dynamics in the Manila clam (Ruditapes philippinarum)
10.3389/fmicb.2026.1803024 · 2026 · External reference
Role of a ficolin in the innate immune mechanisms of Penaeus vannamei against Vibrio parahaemolyticus
10.1016/j.fsi.2025.110950 · 2026 · External reference
Effect of dissolved oxygen concentration changes on the ultrastructure of blood cells in Manila clam (Ruditapes philippinarum)
10.1016/j.fsi.2025.110570 · 2025 · External reference
ROS signaling in innate immunity via oxidative protein modifications
10.3389/fimmu.2024.1359600 · 2024 · External reference
Extracellular traps involved in invertebrate immune mechanisms
10.1016/j.fsi.2022.01.024 · 2022 · External reference
Extracellular traps (ETosis) can be activated through NADPH-dependent and -independent mechanisms in bivalve mollusks
10.1016/j.dci.2019.103585 · 2020 · External reference
Extracellular DNA traps in a ctenophore demonstrate immune cell behaviors in a non-bilaterian
10.1038/s41467-024-46807-6 · 2024 · External reference
Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: production characteristics and antibacterial effects
10.1016/j.dci.2020.103953 · 2021 · External reference
Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum
10.1016/j.dci.2021.104094 · 2021 · External reference
In vitro study of deltamethrin-induced extracellular traps in hemocytes of Ruditapes philippinarum
10.1016/j.ecoenv.2023.114909 · 2023 · External reference
Nonylphenol displays immunotoxicity by triggering hemocyte extracellular traps in Manila clam via ROS burst, ERK pathway and glycolysis
10.1016/j.ecoenv.2024.117145 · 2024 · External reference
NOX family: regulators of reactive oxygen Species balance in tumor cells
10.1096/fj.202500238rrr · 2025 · External reference
Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)
10.1007/s13105-023-00955-3 · 2023 · External reference
Ca2+-binding-region-dependent cell surface localization of NADPH oxidase Nox5
10.1002/1873-3468.14577 · 2023 · External reference
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs
2013 · External reference
Structural basis of human NOX5 activation
10.1038/s41467-024-48467-y · 2024 · External reference
Grass carp Il-2 promotes neutrophil extracellular traps formation via inducing ROS production and autophagy in vitro
10.1016/j.fsi.2023.109261 · 2024 · External reference
Targeting NADPH oxidase and Integrin α5β1 to inhibit neutrophil extracellular traps-mediated metastasis in colorectal cancer
10.3390/ijms242116001 · 2023 · External reference
Florfenicol alleviated lipopolysaccharide (LPS)-induced inflammatory responses in Ctenopharyngodon idella through inhibiting toll/NF-κB signaling pathways
10.1016/j.fsi.2019.08.073 · 2019 · External reference
Various cellular responses of different shrimp haemocyte subpopulations to lipopolysaccharide stimulation
10.1016/j.fsi.2017.08.025 · 2017 · External reference
In vitro effects of 5-Lipoxygenase pathway inhibition on rhinovirus-associated bronchial epithelial inflammation
10.1007/s41030-021-00152-x · 2021 · External reference
Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage
10.1038/ncomms10112 · 2015 · External reference
Myocardial reperfusion injury exacerbation due to ALDH2 deficiency is mediated by neutrophil extracellular traps and prevented by leukotriene C4 inhibition
10.1093/eurheartj/ehae205 · 2024 · External reference
Biosynthetic pathway for leukotrienes is stimulated by lipopolysaccharide and cytokines in pig endometrial stromal cells
10.1038/s41598-025-86787-1 · 2025 · External reference
Deciphering the ancestral mechanisms of neural regeneration through single-cell analyses of jellyfish rhopalium repair
10.1126/sciadv.aeb8034 · 2026 · External reference
Microsomal glutathione transferase 2 modulates LTC4 synthesis and ROS production in Apostichopus japonicus
10.1016/j.molimm.2017.09.002 · 2017 · External reference
Fish species-specific TRIM gene FTRCA1 negatively regulates interferon response through attenuating IRF7 transcription
10.1016/j.fsi.2019.04.297 · 2019 · External reference
Matrix metalloproteinase 9 modulates immune response along with the formation of extracellular traps in flounder (Paralichthys olivaceus)
10.1016/j.fsi.2023.108570 · 2023 · External reference
Hippo-warts-yorkie pathway is crucial for larval survival and shell development in Pacific abalone (Haliotis discus hannai)
2024 · External reference
Vaccine adjuvants induce Formation of intraperitoneal extracellular traps in flounder (Paralichthys olivaceus)
2022 · External reference
Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling
10.1016/j.fsi.2022.08.060 · 2022 · External reference
Leukotriene C4 (LTC4) elicits a respiratory burst in peritoneal macrophages
10.1016/0014-2999(83)90384-9 · 1983 · External reference
CysLT receptor-mediated NOX2 activation is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products
10.3347/phd.24046 · 2024 · External reference
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)
10.1074/jbc.m310268200 · 2004 · External reference
NOX5: from basic biology to signaling and disease
10.1016/j.freeradbiomed.2011.11.023 · 2012 · External reference
Crystal structures and atomic model of NADPH oxidase
10.1073/pnas.1702293114 · 2017 · External reference
Arginine alleviates LPS-induced leukocytes inflammation and apoptosis via adjusted NODs signaling
10.1016/j.fsi.2024.109985 · 2024 · External reference
Cysteinyl leukotrienes in allergic inflammation
10.1146/annurev-pathmechdis-111523-023509 · 2025 · External reference
Pro- and anti-inflammatory mediators change leukotriene B4 and leukotriene C4 synthesis and secretion in an inflamed porcine endometrium
10.1016/j.domaniend.2014.05.001 · 2014 · External reference
Lactate-upregulated NADPH-dependent NOX4 expression via HCAR1/PI3K pathway contributes to ROS-induced osteoarthritis chondrocyte damage
10.1016/j.redox.2023.102867 · 2023 · External reference
Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane
10.1007/s00281-008-0118-3 · 2008 · External reference
NOX-derived ROS modulates the antibacterial immune responses in coelomocytes of Apostichopus japonicus
10.1016/j.aquaculture.2024.740953 · 2024 · External reference
AMPK-mediated glutaminolysis maintains coelomocytes redox homeostasis in Vibrio splendidus-challenged Apostichopus japonicus
10.1016/j.fsi.2022.02.012 · 2022 · External reference
Invertebrate extracellular phagocyte traps show that chromatin is an ancient defence weapon
10.1038/ncomms5627 · 2014 · External reference
High throughput measurement of extracellular DNA release and quantitative NET Formation in human neutrophils in vitro
2016 · External reference
Targeting ETosis by miR-155 inhibition mitigates mixed granulocytic asthmatic lung inflammation
10.3389/fimmu.2022.943554 · 2022 · External reference
