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References from Precision Oncology in Pediatric Cancer Surgery. Local targets link to admitted publications; unresolved targets remain external evidence.
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
10.1056/nejmoa1105185 · 2011 · External reference
Unresolved reference
External reference
Current causes of death in children and adolescents in the United States
10.1056/nejmc2201761 · 2022 · External reference
Children’s Oncology Group’s 2013 blueprint for research: survivorship and outcomes
10.1002/pbc.24422 · 2013 · External reference
Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children’s oncology group study
10.1200/jco.2007.13.8925 · 2009 · External reference
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
10.1038/nature25795 · 2018 · External reference
The genomic landscape of pediatric cancers: Implications for diagnosis and treatment
10.1126/science.aaw3535 · 2019 · External reference
Mutational heterogeneity in cancer and the search for new cancer-associated genes
10.1038/nature12213 · 2013 · External reference
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
10.1038/ng.3333 · 2015 · External reference
Mutational dynamics between primary and relapse neuroblastomas
10.1038/ng.3349 · 2015 · External reference
The landscape of genomic alterations across childhood cancers
10.1038/nature25480 · 2018 · External reference
A first-generation pediatric cancer dependency map
10.1038/s41588-021-00819-w · 2021 · External reference
Epigenetic changes in pediatric solid tumors: promising new targets
10.1158/1078-0432.ccr-11-1921 · 2012 · External reference
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
10.1038/nm.4439 · 2018 · External reference
Divergent clonal selection dominates medulloblastoma at recurrence
10.1038/nature16478 · 2016 · External reference
Genomic ALK alterations in primary and relapsed neuroblastoma
10.1038/s41416-023-02208-y · 2023 · External reference
TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
10.1038/ng.3438 · 2015 · External reference
BRAF alterations in primary brain tumors
2018 · External reference
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
10.1038/28212 · 1998 · External reference
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
10.1172/jci64400 · 2012 · External reference
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
10.1038/nature10833 · 2012 · External reference
DNA methylation-based classification of central nervous system tumours
10.1038/nature26000 · 2018 · External reference
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin’s lymphoma
10.1056/nejmoa1411087 · 2015 · External reference
Phase II study of ipilimumab in adolescents with unresectable stage III or IV malignant melanoma
10.1016/j.ejca.2017.09.032 · 2017 · External reference
The FDA approval of pembrolizumab for adult and pediatric patients with tumor mutational burden (TMB) ≥10: a decision centered on empowering patients and their physicians
10.1016/j.annonc.2020.07.002 · 2020 · External reference
Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children’s Oncology Group Study
10.1200/jco.2017.73.4830 · 2017 · External reference
Entrectinib and other ALK/TRK inhibitors for the treatment of neuroblastoma
10.2147/dddt.s147384 · 2018 · External reference
Activity of Crizotinib in Patients with ALK-Aberrant Relapsed/Refractory Neuroblastoma: A Children’s Oncology Group Study (ADVL0912)
10.1158/1078-0432.ccr-20-4224 · 2021 · External reference
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma
10.1056/nejmoa0911123 · 2010 · External reference
Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients
1984 · External reference
Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial
10.1016/s1470-2045(18)30578-3 · 2018 · External reference
Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors: The Individualized Cancer Therapy (iCat) Study
10.1001/jamaoncol.2015.5689 · 2016 · External reference
Molecular Screening for Cancer Treatment Optimization (MOSCATO-01) in Pediatric Patients: A Single-Institutional Prospective Molecular Stratification Trial
10.1158/1078-0432.ccr-17-0381 · 2017 · External reference
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
10.1038/s41591-020-1072-4 · 2020 · External reference
Precision medicine in pediatric oncology
10.1097/mop.0000000000000570 · 2018 · External reference
Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children’s Oncology Group Pediatric MATCH Trial
10.1200/jco.21.02838 · 2022 · External reference
Target and Agent Prioritization for the Children’s Oncology Group-National Cancer Institute Pediatric MATCH Trial
10.1093/jnci/djw274 · 2017 · External reference
10.1016/j.ejca.2021.03.032
10.1016/j.ejca.2021.03.032 · 2021 · External reference
Does aggressive surgical resection improve survival in advanced stage 3 and 4 neuroblastoma? A systematic review and meta-analysis
10.3109/08880018.2014.947009 · 2014 · External reference
Is complete surgical resection of stage 4 neuroblastoma a prerequisite for optimal survival or may >95 % tumour resection suffice?
10.1007/s00383-012-3109-3 · 2012 · External reference
A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era
10.1158/2159-8290.cd-21-1094 · 2022 · External reference
Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies
10.1158/2326-6066.cir-19-0692 · 2020 · External reference
Neuroblastoma
10.1038/nrdp.2016.78 · 2016 · External reference
The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report
10.1200/jco.2008.16.6785 · 2009 · External reference
Advances in emerging drugs for the treatment of neuroblastoma
10.1080/14728214.2017.1294159 · 2017 · External reference
Clinical and biologic features predictive of survival after relapse of neuroblastoma: a report from the International Neuroblastoma Risk Group project
10.1200/jco.2010.34.3392 · 2011 · External reference
Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy
10.3389/fonc.2020.01000 · 2020 · External reference
Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032
10.1158/1078-0432.ccr-20-3909 · 2021 · External reference
Irinotecan, Temozolomide, and Dinutuximab With GM-CSF in Children With Refractory or Relapsed Neuroblastoma: A Report From the Children’s Oncology Group
10.1200/jco.20.00203 · 2020 · External reference
Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo
10.4161/onci.19864 · 2012 · External reference
Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission
10.1158/1078-0432.ccr-13-1012 · 2014 · External reference
Long path to MYC inhibition approaches clinical trials
10.1038/s41568-019-0141-9 · 2019 · External reference
Prognostic significance of age, MYCN oncogene amplification, tumor cell ploidy, and histology in 110 infants with stage D(S) neuroblastoma: the pediatric oncology group experience--a pediatric oncology group study
10.1200/jco.1998.16.6.2007 · 1998 · External reference
Targeting of the MYCN protein with small molecule c-MYC inhibitors
10.1371/journal.pone.0097285 · 2014 · External reference
Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells
10.1186/s12935-019-1072-y · 2020 · External reference
ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma
10.1158/0008-5472.can-07-6866 · 2008 · External reference
Targeting MYCN in neuroblastoma by BET bromodomain inhibition
10.1158/2159-8290.cd-12-0418 · 2013 · External reference
Modelling Myc inhibition as a cancer therapy
10.1038/nature07260 · 2008 · External reference
Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene
10.1128/mcb.00248-19 · 2019 · External reference
Direct MYC Inhibitor Passes First Clinical Test
10.1158/2159-8290.cd-nb2022-0067 · 2023 · External reference
Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children’s Oncology Group phase 1 consortium study
10.1016/s1470-2045(13)70095-0 · 2013 · External reference
A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma
10.1002/ijc.30440 · 2017 · External reference
Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways
10.18632/oncotarget.10070 · 2016 · External reference
The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway
10.1038/onc.2009.80 · 2009 · External reference
RAS-MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma
10.1158/0008-5472.can-18-1045 · 2018 · External reference
Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53
10.1093/jnci/djp355 · 2009 · External reference
Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis
10.1016/j.bmcl.2013.08.018 · 2013 · External reference
Absence of p53 gene mutations in primary neuroblastomas
1993 · External reference
Reactivation of p53 via MDM2 inhibition
10.1038/cddis.2015.302 · 2015 · External reference
Targeted molecular therapy for neuroblastoma: the ARF/MDM2/p53 axis
10.1093/jnci/djp376 · 2009 · External reference
The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma
10.1038/cddiscovery.2015.26 · 2015 · External reference
Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma
10.1007/s10456-011-9210-8 · 2011 · External reference
Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children’s Oncology Group phase I consortium report
10.1200/jco.2009.25.9119 · 2010 · External reference
Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition
10.1158/1078-0432.ccr-15-1449 · 2016 · External reference
Exosome-like Extracellular Vesicles from MYCN-amplified Neuroblastoma Cells Contain Oncogenic miRNAs
2015 · External reference
Wilms tumor: "State-of-the-art" update, 2016
10.1053/j.sempedsurg.2016.09.003 · 2016 · External reference
Advances in Wilms Tumor Treatment and Biology: Progress Through International Collaboration
10.1200/jco.2015.62.1888 · 2015 · External reference
Systematic review of the immunological landscape of Wilms tumors
10.1016/j.omto.2021.06.016 · 2021 · External reference
Relationship of tumour-associated macrophages with poor prognosis in Wilms’ tumour
10.1016/j.jpurol.2020.03.016 · 2020 · External reference
Characterization of the inflammatory microenvironment and identification of potential therapeutic targets in Wilms tumors
10.1016/j.tranon.2014.05.008 · 2014 · External reference
Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors
10.1002/pbc.26613 · 2017 · External reference
Various checkpoint molecules, and tumor-infiltrating lymphocytes in common pediatric solid tumors: Possibilities for novel immunotherapy
10.1080/08880018.2019.1578843 · 2019 · External reference
Biomarker recommendation for PD-1/PD-L1 immunotherapy development in pediatric cancer based on digital image analysis of PD-L1 and immune cells
10.1002/cjp2.152 · 2020 · External reference
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial
10.1016/s1470-2045(19)30671-0 · 2020 · External reference
CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
10.1158/1078-0432.ccr-18-0432 · 2019 · External reference
Detection and characterization of N-glycolyated gangliosides in Wilms tumor by immunohistochemistry
10.2350/08-10-0544.1 · 2010 · External reference
A Phase I Study of the Anti-Idiotype Vaccine Racotumomab in Neuroblastoma and Other Pediatric Refractory Malignancies
10.1002/pbc.25631 · 2015 · External reference
Phase 2 trial of recombinant tumor necrosis factor-alpha in combination with dactinomycin in children with recurrent Wilms tumor
10.1097/cji.0b013e3181826d72 · 2008 · External reference
Phase I study of tumor necrosis factor-alpha and actinomycin D in pediatric patients with cancer: a Children’s Cancer Group study
10.1097/00002371-199408000-00006 · 1994 · External reference
Trends in International Incidence of Pediatric Cancers in Children Under 5 Years of Age: 1988-2012
10.1093/jncics/pkz007 · 2019 · External reference
Cancer Statistics, 2021
2021 · External reference
Risk of hepatoblastoma in familial adenomatous polyposis
10.1016/s0022-3476(05)80297-5 · 1991 · External reference
Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry
10.1016/s0022-3476(98)70008-3 · 1998 · External reference
Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups
10.1002/hep.28888 · 2017 · External reference
New insights into diagnosis and therapeutic options for proliferative hepatoblastoma
10.1002/hep.29672 · 2018 · External reference
Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
10.1016/j.jhep.2020.03.025 · 2020 · External reference
Wnt/β-Catenin Signaling in Liver Cancers
10.3390/cancers11070926 · 2019 · External reference
Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice
10.1002/hep.28975 · 2017 · External reference
Current therapeutic strategies for childhood hepatic tumors: surgical and interventional treatments for hepatoblastoma
10.1007/s10147-013-0625-7 · 2013 · External reference
Effect of sorafenib combined with cytostatic agents on hepatoblastoma cell lines and xenografts
10.1038/bjc.2012.539 · 2013 · External reference
Current Approaches in Hepatoblastoma-New Biological Insights to Inform Therapy
10.1007/s11912-022-01230-2 · 2022 · External reference
Activation of phosphatidylinositol-3’-kinase/AKT signaling is essential in hepatoblastoma survival
10.1158/1078-0432.ccr-08-2878 · 2009 · External reference
Rapamycin blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients
10.1016/j.ejca.2011.12.032 · 2012 · External reference
Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma
10.18632/oncotarget.25205 · 2018 · External reference
Transforming growth factor-beta1-induced Smad signaling, cell-cycle arrest and apoptosis in hepatoma cells
10.1093/carcin/22.3.447 · 2001 · External reference
Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas
10.1007/s100380300008 · 2003 · External reference
Volasertib preclinical activity in high-risk hepatoblastoma
10.18632/oncotarget.27237 · 2019 · External reference
Olaparib Inhibits Tumor Growth of Hepatoblastoma in Patient-Derived Xenograft Models
10.1002/hep.31919 · 2021 · External reference
MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma
10.1038/s41598-021-82542-4 · 2021 · External reference
Targeting EpCAM (CD326) for immunotherapy in hepatoblastoma
10.4161/onci.22620 · 2013 · External reference
Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2005
10.1002/cncr.24465 · 2009 · External reference
Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IV
10.1200/jco.2003.06.129 · 2003 · External reference
PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children’s oncology group report
10.1002/pbc.24532 · 2013 · External reference
Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma
10.1038/sj.onc.1204599 · 2001 · External reference
RGD liposome-protamine-siRNA (LPR) nanoparticles targeting PAX3-FOXO1 for alveolar rhabdomyosarcoma therapy
10.1016/j.jconrel.2016.05.063 · 2016 · External reference
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma
10.1126/scisignal.aau7632 · 2018 · External reference
Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma
10.1016/j.ejca.2011.09.021 · 2012 · External reference
Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children’s Oncology Group
10.1200/jco.19.00576 · 2019 · External reference
10.1016/j.ejca.2018.02.011
10.1016/j.ejca.2018.02.011 · 2018 · External reference
Phase 2 trial of cixutumumab in children, adolescents, and young adults with refractory solid tumors: a report from the Children’s Oncology Group
10.1002/pbc.24605 · 2014 · External reference
The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma: A report from the Children’s Oncology Group
10.1002/cncr.31770 · 2019 · External reference
Phase II study of cixutumumab in combination with temsirolimus in pediatric patients and young adults with recurrent or refractory sarcoma: a report from the Children’s Oncology Group
10.1002/pbc.25334 · 2015 · External reference
Phase 2 trial of sorafenib in children and young adults with refractory solid tumors: A report from the Children’s Oncology Group
10.1002/pbc.25548 · 2015 · External reference
Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols
10.1200/jco.2002.20.3.776 · 2002 · External reference
Neoadjuvant chemotherapy in the treatment of osteosarcoma of the extremities: preliminary results in 131 cases treated preoperatively with methotrexate and cisdiamminoplatinum
1988 · External reference
Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma
10.1016/j.celrep.2014.03.003 · 2014 · External reference
Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma
10.18632/oncotarget.18236 · 2017 · External reference
Osteosarcoma: Current Treatment and a Collaborative Pathway to Success
10.1200/jco.2014.59.4895 · 2015 · External reference
Novel Immunotherapies for Osteosarcoma
10.3389/fonc.2022.830546 · 2022 · External reference
Exosomal communication by metastatic osteosarcoma cells modulates alveolar macrophages to an M2 tumor-promoting phenotype and inhibits tumoricidal functions
10.1080/2162402x.2020.1747677 · 2020 · External reference
Ganglioside GD2 as a therapeutic target for antibody-mediated therapy in patients with osteosarcoma
10.1002/cncr.28461 · 2014 · External reference
Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma
10.1002/pbc.25688 · 2016 · External reference
Initial testing (stage 1) of glembatumumab vedotin (CDX-011) by the pediatric preclinical testing program
10.1002/pbc.25099 · 2014 · External reference
Phase II trial of the glycoprotein non-metastatic B-targeted antibody-drug conjugate, glembatumumab vedotin (CDX-011), in recurrent osteosarcoma AOST1521: A report from the Children’s Oncology Group
10.1016/j.ejca.2019.08.015 · 2019 · External reference
Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells
10.1242/jcs.094029 · 2012 · External reference
Apatinib plus camrelizumab (anti-PD1 therapy, SHR-1210) for advanced osteosarcoma (APFAO) progressing after chemotherapy: a single-arm, open-label, phase 2 trial
10.1136/jitc-2020-000798 · 2020 · External reference
Adoptive transfer of TILs plus anti-PD1 therapy: An alternative combination therapy for treating metastatic osteosarcoma
10.1016/j.jbo.2020.100332 · 2020 · External reference
Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy - Observational prospective single institution analysis
10.1016/j.jbo.2021.100362 · 2021 · External reference
Inhibition of M2-like macrophages by all-trans retinoic acid prevents cancer initiation and stemness in osteosarcoma cells
10.1038/s41401-019-0262-4 · 2019 · External reference
Mechanism-based cancer therapy: resistance to therapy, therapy for resistance
10.1038/onc.2014.314 · 2015 · External reference
Unresolved reference
2008 · External reference
Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth
10.1001/jama.2015.10080 · 2015 · External reference
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study
10.1016/j.ejca.2016.06.009 · 2016 · External reference
Phase II study of neoadjuvant bevacizumab and radiotherapy for resectable soft tissue sarcomas
10.1016/j.ijrobp.2010.07.024 · 2011 · External reference
Effect of tyrosine kinase inhibitors on wound healing and tissue repair: implications for surgery in cancer patients
10.1007/s40264-014-0139-x · 2014 · External reference
A systematic approach to minimizing wound problems for de novo sirolimus-treated kidney transplant recipients
10.1097/tp.0b013e318192dd56 · 2009 · External reference
Risk of bleeding associated with antiangiogenic monoclonal antibodies bevacizumab and ramucirumab: a meta-analysis of 85 randomized controlled trials
10.2147/ott.s166151 · 2018 · External reference
Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma
10.1200/jco.18.02374 · 2019 · External reference
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
10.1038/s41587-021-00857-z · 2021 · External reference
Blood-Derived Liquid Biopsies Using Foundation One(®) Liquid CDx for Children and Adolescents with High-Risk Malignancies: A Monocentric Experience
10.3390/cancers14112774 · 2022 · External reference
Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab
10.1038/s43018-020-0096-5 · 2020 · External reference
Analysis of circulating tumor DNA to monitor metastatic breast cancer
10.1056/nejmoa1213261 · 2013 · External reference
Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study
10.1038/s41591-019-0407-5 · 2019 · External reference
Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study
10.1186/s13073-021-00969-w · 2021 · External reference