Research graph
References from Laser Interstitial Thermal Therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors
10.1097/00006123-199805000-00054 · 1998 · External reference
Thirty-day outcomes after craniotomy for primary malignant brain tumors: a National Surgical Quality Improvement Program analysis
10.1093/neuros/nyy001 · 2018 · External reference
Effect of extent of resection on survival of patients with glioblastoma, IDH–Wild-Type, WHO grade 4 (WHO 2021): systematic review and meta-analysis
10.1016/j.wneu.2022.12.052 · 2023 · External reference
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
10.1056/nejmoa043330 · 2005 · External reference
Laser-induced thermal therapy for tumor ablation
10.1615/critrevbiomedeng.v38.i1.70 · 2010 · External reference
History of ablation therapies in neurosurgery
10.1016/j.nec.2022.12.002 · 2023 · External reference
MR-monitored LITT as a palliative concept in patients with high grade gliomas: preliminary clinical experience
10.1002/jmri.1880080140 · 1998 · External reference
Laser hyperthermia: past, present, and future
10.1093/neuonc/noac208 · 2022 · External reference
Magnetic resonance thermometry-guided laser-induced thermal therapy for intracranial neoplasms
10.1227/neu.0b013e31826101d4 · 2012 · External reference
Blood-brain barrier disruption following MR-guided laser interstitial thermal therapy
2025 · External reference
Modulating the glioma microenvironment with laser interstitial thermal therapy: mechanisms and therapeutic implications
10.1007/s11060-025-05305-5 · 2025 · External reference
Phototherapy of tumors
10.1007/bf01655209 · 1983 · External reference
Renaissance of laser interstitial thermal ablation
10.3171/2014.12.focus14762 · 2015 · External reference
Interstitial thermotherapy of central brain tumors with the Nd:YAG laser under real-time monitoring by MRI
10.1089/clm.1991.9.79 · 1991 · External reference
Preliminary experience with MR-guided thermal ablation of brain tumors
1995 · External reference
Interstitial laser hyperthermia in tumour therapy
1990 · External reference
Interstitial 1.06 Nd:YAG laser thermotherapy for brain tumors under real-time monitoring of MRI: experimental study and phase I clinical trial
10.1089/clm.1992.10.355 · 1992 · External reference
Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia
10.1080/0265673031000119006 · 2003 · External reference
Noninvasive MRI thermometry with the proton resonance frequency method: study of susceptibility effects
10.1002/mrm.1910340313 · 1995 · External reference
Comparison of magnetic resonance images and the histopathological findings of lesions induced by interstitial laser photocoagulation in the brain
10.1002/lsm.1900130110 · 1993 · External reference
Laser interstitial thermal therapy
2020 · External reference
Stereotactic interstitial laser-hyperthermia using Nd-YAG laser
10.1159/000100263 · 1990 · External reference
Laser interstitial thermal therapy for intra-axial brain tumors: everything the neuroradiologist should know
10.3174/ajnr.a8427 · 2025 · External reference
Preclinical assessment of a noncooled MR thermometry–based neurosurgical laser therapy system
10.3171/2023.12.jns232154 · 2024 · External reference
MR thermometry
10.1002/jmri.21265 · 2008 · External reference
Methods of monitoring thermal ablation of soft tissue tumors – a comprehensive review
10.1002/mp.15439 · 2022 · External reference
Stereotactic laser interstitial thermal therapy for recurrent high-grade gliomas
10.1227/neu.0000000000001443 · 2016 · External reference
10.1007/3-540-28137-1_5
10.1007/3-540-28137-1_5 · External reference
Magnetic resonance-guided laser induced thermal therapy for glioblastoma multiforme: a review
10.1155/2014/761312 · 2014 · External reference
Heat-resistant cylindrical diffuser for interstitial laser coagulation: comparison with the bare-tip fiber in a porcine liver model
10.1002/(sici)1096-9101(1997)20:3<304::aid-lsm9>3.0.co;2-u · 1997 · External reference
Complication avoidance in laser interstitial thermal therapy: lessons learned
10.3171/2016.3.jns152147 · 2017 · External reference
A novel use of the NeuroBlate SideFire probe for minimally invasive disconnection of a hypothalamic hamartoma in a child with gelastic seizures
10.3171/2017.9.peds1747 · 2018 · External reference
The ClearPoint prism® laser ablation System: a new platform for Laser Interstitial Thermal Therapy (LITT) in neuro-oncology
10.1227/neuprac.0000000000000084 · 2024 · External reference
Laser interstitial thermal therapy in gliomas
10.1016/j.canlet.2020.01.024 · 2020 · External reference
Laser neurosurgery: a systematic analysis of magnetic resonance-guided laser interstitial thermal therapies
10.1016/j.jocn.2016.10.019 · 2017 · External reference
Tissue ablation dynamics during magnetic resonance–guided, laser-induced thermal therapy
10.1227/neu.0000000000000732 · 2015 · External reference
Assessment of irrigation dynamics in magnetic-resonance guided laser induced thermal therapy (MRgLITT)
10.1002/lsm.22332 · 2015 · External reference
Results of the NeuroBlate system first-in-humans phase I clinical trial for recurrent glioblastoma
10.3171/2013.1.jns1291 · 2013 · External reference
CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2017–2021
10.1093/neuonc/noae145 · 2024 · External reference
Laser interstitial thermal therapy as a primary treatment for deep inaccessible gliomas
10.1093/neuros/nyy238 · 2019 · External reference
Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme
10.1227/01.neu.0000349763.42238.e9 · 2009 · External reference
Thirty-day outcomes after craniotomy for primary malignant brain tumors
10.1093/neuros/nyy001 · 2018 · External reference
Frailty as a predictor of neurosurgical outcomes in brain tumor patients: a systematic review and meta-analysis
2023 · External reference
Barriers to expeditious post-operative chemotherapy for patients with glioblastoma
10.1016/j.clineuro.2026.109352 · 2026 · External reference
Safety and efficacy of laser interstitial thermal therapy as upfront therapy in primary glioblastoma and IDH-mutant astrocytoma: a meta-analysis
10.3390/cancers16112131 · 2024 · External reference
Survival prediction in glioblastoma: 10-year follow-up from the Dutch Neurosurgery Quality Registry
10.1007/s11060-025-05080-3 · 2025 · External reference
National trends and factors predicting outcomes following laser interstitial thermal therapy for brain lesions: nationwide inpatient sample analysis
10.1016/j.wneu.2020.03.124 · 2020 · External reference
Laser interstitial thermal therapy for the treatment of primary and metastatic brain tumors: a systematic review and meta-analysis
10.1016/j.wneu.2022.12.079 · 2023 · External reference
The safety and efficacy of laser interstitial thermal therapy for newly diagnosed deep-seated low-grade glioma: a pilot study comparing outcomes with a surgical cohort
10.1227/neu.0000000000003951 · 2026 · External reference
Recurring glioblastoma: a case for reoperation?
2017 · External reference
Association of the extent of resection with survival in glioblastoma
10.1001/jamaoncol.2016.1373 · 2016 · External reference
Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma
10.1093/neuonc/not137 · 2014 · External reference
A cohort study on prognostic factors for laser interstitial thermal therapy success in newly diagnosed glioblastoma
10.1093/neuros/nyab193 · 2021 · External reference
The impact of extent of ablation on survival of patients with newly diagnosed glioblastoma treated with laser interstitial thermal therapy: a large single-institutional cohort
10.1227/neu.0000000000002430 · 2023 · External reference
Laser interstitial thermal therapy in neurosurgery: a single-surgeon experience of 313 patients
10.3171/2024.3.jns245 · 2024 · External reference
Neurocognitive outcomes in patients with brain metastases: a systematic review
10.1016/s1470-2045(25)00525-x · 2025 · External reference
Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial
10.1016/s1470-2045(17)30414-x · 2017 · External reference
Laser thermal therapy: real-time MRI-guided and computer-controlled procedures for metastatic brain tumors
10.1002/lsm.21138 · 2011 · External reference
The role of laser interstitial thermal therapy in surgical neuro-oncology: series of 100 consecutive patients
10.1093/neuros/nyz424 · 2020 · External reference
Outcomes and principles of patient selection for laser interstitial thermal therapy for metastatic brain tumor management: a multisite institutional case series
10.1016/j.wneu.2022.06.095 · 2022 · External reference
Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience
10.3171/2016.7.focus16227 · 2016 · External reference
Repeated in-field radiosurgery for locally recurrent brain metastases: feasibility, results and survival in a heavily treated patient cohort
10.1371/journal.pone.0198692 · 2018 · External reference
Reirradiation with stereotactic radiosurgery after local or marginal recurrence of brain metastases from previous radiosurgery
10.1016/j.ijrobp.2021.10.008 · 2022 · External reference
Hypofractionated stereotactic radiosurgery (HSRS) as a salvage treatment for brain metastases failing prior stereotactic radiosurgery (SRS)
10.1007/s11060-023-04265-y · 2023 · External reference
Laser interstitial thermal therapy for intracranial dural-based lesions: a single center case series of 20 patients
10.1016/j.clineuro.2026.109384 · 2026 · External reference
MR-guided stereotactic laser ablation of epileptogenic foci in children
10.1016/j.yebeh.2012.04.135 · 2012 · External reference
Magnetic resonance–guided laser interstitial thermal therapy for mesial temporal epilepsy: a case series analysis of outcomes and complications at 2-Year Follow-Up
10.1016/j.wneu.2019.03.057 · 2019 · External reference
Interstitial thermal therapy in mesial temporal lobe epilepsy
10.1001/jamaneurol.2025.1897 · 2025 · External reference
MRI-guided laser interstitial thermal therapy in epilepsy: indications, technique and outcome in an adult population. A single-center data analysis
10.1007/s00701-025-06429-3 · 2025 · External reference
Outcome of surgery for hypothalamic hamartoma-related epilepsy
10.1212/wnl.0000000000210060 · 2024 · External reference
Magnetic resonance imaging-guided laser interstitial thermal therapy for epilepsy: systematic review of technique, indications, and outcomes
10.1093/neuros/nyz556 · 2020 · External reference
Surgical treatment of hypothalamic hamartomas
10.1007/s10143-020-01298-z · 2021 · External reference
Focal cortical dysplasia and refractory epilepsy: role of multimodality imaging and outcome of surgery
10.3174/ajnr.a6041 · 2019 · External reference
MR-guided laser interstitial thermal therapy for pediatric drug-resistant lesional epilepsy
10.1111/epi.13106 · 2015 · External reference
A comparison between magnetic resonance-guided laser interstitial thermal therapy and resective surgery for drug-resistant epilepsy in patients with MRI-positive focal cortical dysplasia: a systematic review and meta-analysis
10.1016/j.eplepsyres.2025.107660 · 2025 · External reference
MRI-guided stereotactic laser corpus callosotomy for epilepsy: distinct methods and outcomes
10.3171/2020.7.jns20498 · 2021 · External reference
Laser ablation for corpus callosotomy: systematic review and pooled analysis
10.1016/j.seizure.2022.02.002 · 2022 · External reference
Single-institution comparative study of magnetic resonance–guided laser interstitial thermal therapy and open corpus callosotomy
10.1016/j.wneu.2023.03.082 · 2023 · External reference
The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
10.1038/s41568-019-0205-x · 2020 · External reference
Therapeutic enhancement of blood–brain and blood–tumor barriers permeability by laser interstitial thermal therapy
2020 · External reference
Prolonged blood-brain barrier disruption following laser interstitial ablation in epilepsy: a case series with a case report of postablation optic neuritis
10.1016/j.wneu.2017.05.009 · 2017 · External reference
Hyperthermic laser ablation of recurrent glioblastoma leads to temporary disruption of the peritumoral blood brain barrier
10.1371/journal.pone.0148613 · 2016 · External reference
MR-guided laser interstitial thermal therapy followed by early application of temozolomide for recurrent IDH-wildtype glioblastomas: preliminary results from a prospective study
10.1007/s10143-025-03402-7 · 2025 · External reference
A phase II study of laser interstitial thermal therapy combined with doxorubicin in patients with recurrent glioblastoma
2021 · External reference
Effects of the proteasome inhibitor ritonavir on glioma growth in vitro and in vivo
10.1158/1535-7163.129.3.2 · 2004 · External reference
CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma
10.1084/jem.20211631 · 2022 · External reference
Effects of HIV protease inhibitor ritonavir on akt-regulated cell proliferation in breast cancer
10.1158/1078-0432.ccr-05-1167 · 2006 · External reference
Antitumour effects of antiretroviral therapy
10.1038/nrc1479 · 2004 · External reference
Antiretroviral drug repositioning for glioblastoma
10.3390/cancers16091754 · 2024 · External reference
The future of clinical trials in surgical neuro-oncology is bright
10.3390/brainsci15121274 · 2025 · External reference
Synergistic Treatment with Antiretrovirals and Laser Interstitial Thermal ThErapy (STARLITE) for unresectable glioblastoma: a phase 1 study protocol
10.1371/journal.pone.0328204 · 2025 · External reference
Laser ablation: heating up the anti-tumor response in the intracranial compartment
10.1016/j.addr.2022.114311 · 2022 · External reference
A comprehensive single-cell analysis reveals the impact of laser interstitial thermal therapy on the tumor microenvironment in glioblastoma
10.1093/jimmun/vkaf327 · 2026 · External reference
Laser interstitial thermal therapy induces robust local immune response for newly diagnosed glioblastoma with long-term survival and disease control
10.1097/cji.0000000000000485 · 2023 · External reference
Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter
10.1093/neuonc/noac116 · 2022 · External reference
Effect of nivolumab vs bevacizumab in patients with recurrent glioblastoma
10.1001/jamaoncol.2020.1024 · 2020 · External reference
Randomized phase II and biomarker study of pembrolizumab plus bevacizumab versus pembrolizumab alone for patients with recurrent glioblastoma
10.1158/1078-0432.ccr-20-2500 · 2021 · External reference
Anti-PD-1 and anti-PD-L1 antibodies for glioma
2025 · External reference
Understanding the immunosuppressive microenvironment of glioma: mechanistic insights and clinical perspectives
10.1186/s13045-024-01544-7 · 2024 · External reference
Laser interstitial thermal therapy and adjuvant pembrolizumab in recurrent high-grade astrocytoma: a phase 1/randomized phase 2b trial
10.1038/s41467-026-69522-w · 2026 · External reference
Neoadjuvant PD1 blockade with laser interstitial thermal therapy for recurrent high-grade glioma
10.1016/j.jocn.2025.111823 · 2026 · External reference
Intracerebral laser interstitial thermal therapy followed by tumor resection to minimize cerebral edema
10.3171/2016.7.focus16224 · 2016 · External reference
Hybrid therapy for newly diagnosed and recurrent glioblastoma: staged procedure integrating open surgical resection with laser interstitial thermal therapy
10.1227/ons.0000000000001668 · 2026 · External reference
Laser interstitial thermal therapy followed by consolidation stereotactic radiosurgery (LITT-cSRS) in patients with newly diagnosed brain metastasis
10.1007/s11060-024-04712-4 · 2024 · External reference
Combination laser interstitial thermal therapy plus stereotactic radiotherapy increases time to progression for biopsy-proven recurrent brain metastases
2022 · External reference
