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References from Genistein enhances expression of extracellular regulated kinases (ERK) 1/2, and learning and memory of mouse. Local targets link to admitted publications; unresolved targets remain external evidence.
Soybean phytoestrogen intake and cancer risk
10.1093/jn/125.3_suppl.757s · 1995 · External reference
Mitogen-activated protein kinase signalling and ERK1/2 biostability in asthma
10.1111/j.1365-2222.2010.03658.x · 2011 · External reference
The novel object recognition memory: neurobiology, test procedure, and its modifications
10.1007/s10339-011-0430-z · 2012 · External reference
Effects of genistein in the maternal diet on reproductive development and spatial learning in male rats
10.1016/j.yhbeh.2009.12.013 · 2010 · External reference
BDNF is essential to promote persistence of long-term memory storage
10.1073/pnas.0711863105 · 2008 · External reference
Recall and reconsolidation of contextual fear memory: differential control by ERK and Zif 268 expression dosage
10.1371/journal.pone.0072006 · 2013 · External reference
Comparative dynamics of MAPK/ERK signalling components and immediate early genes in the hippocampus and amygdala following contextual fear conditioning and retrieval
10.1007/s00429-013-0529-3 · 2014 · External reference
A Role for ERK2 in reconsolidation of fear memories in mice
10.1016/j.nlm.2006.01.003 · 2006 · External reference
Analysis of the presynaptic signaling mechanisms underlying the inhibition of LTP in rat dentate gyrus by the tyrosine kinase inhibitor, genistein
10.1002/hipo.10036 · 2002 · External reference
A novel role for protein synthesis in long-term neuronal plasticity: maintaining reduced post burst after hyperpolarization
10.1523/jneurosci.5005-09.2010 · 2010 · External reference
Beta estrogen receptor knockout (BERKO) mice present attenuated hippocampal CA1 long-term potentiation and related memory deficits in contextual fear conditioning
10.1016/j.bbr.2005.05.011 · 2005 · External reference
Activation of extracellular signal-regulated kinase- mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning
10.1111/j.1460-9568.2004.03824.x · 2005 · External reference
Phosphorylation of extra-nuclear ERK/MAPK is required for long-term memory consolidation in the crab Chasmagnathus
10.1016/j.bbr.2004.09.005 · 2005 · External reference
Eating soya improves human memory
10.1007/s002130100845 · 2001 · External reference
The role of the extracellular signal-regulated kinase pathway in memory encoding
10.1515/revneuro.2006.17.6.619 · 2006 · External reference
BDNF-induced LTP in dentate gyrus is impaired with age: analysis of changes in cell signaling events
10.1016/j.neurobiolaging.2004.01.003 · 2004 · External reference
One-trial aversive learning induces late changes in hippocampal CaMKII alpha, Homer 1a, Syntaxin 1a and ERK2 protein levels
10.1016/j.molbrainres.2004.08.016 · 2004 · External reference
MAP kinase and pain
10.1016/j.brainresrev.2008.12.011 · 2009 · External reference
Genistein attenuates isoflurane-induced neurotoxicity and improves impaired spatial learning and memory by regulating cAMP/CREB and BDNF-TrkB-PI3K/Akt signaling. Korean
2017 · External reference
Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory
10.1523/jneurosci.23-12-05354.2003 · 2003 · External reference
Genistein improves spatial learning and memory in male rats with elevated glucose level during memory consolidation
10.1016/j.physbeh.2014.12.005 · 2015 · External reference
Memory reconsolidation of an inhibitory avoidance task in mice involves cytosolic ERK2 bidirectional modulation
10.1016/j.neuroscience.2015.03.019 · 2015 · External reference
Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease
10.1371/journal.pone.0014192 · 2010 · External reference
ERK1/2: A Key Cellular component for the formation, retrieval, reconsolidation and persistence of memory
2018 · External reference
Genistein improves 3-NPA-induced memory impairment in ovariectomized rats: impact of its antioxidant, anti-inflammatory and acetylcholinesterase modulatory properties
10.1371/journal.pone.0117223 · 2015 · External reference
A novel retrieval-dependent memory process revealed by the arrest of ERK1/2 activation in the basolateral amygdala
10.1523/jneurosci.3273-17.2018 · 2018 · External reference
Reconsolidation and extinction are dissociable and mutually exclusive processes: behavioral and molecular evidence
10.1523/jneurosci.4001-13.2014 · 2014 · External reference
Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory
10.1016/j.neuron.2005.08.006 · 2005 · External reference
ERK in learning and memory: a review of recent research
10.3390/ijms11010222 · 2010 · External reference
Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer’s disease
10.1016/j.neuropharm.2019.01.030 · 2019 · External reference
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
10.1038/sj.onc.1210422 · 2007 · External reference
The phytoestrogen genistein produces similar effects as 17β-estradiol on anxiety-like behavior in rats at 12 weeks after ovariectomy
10.1155/2017/9073816 · 2017 · External reference
Role of Akt and ERK signaling in the neurogenesis following brain ischemia
10.1016/s0074-7742(09)85026-5 · 2009 · External reference
Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system
10.1002/(sici)1096-9861(19971201)388:4<507::aid-cne1>3.0.co;2-6 · 1997 · External reference
Ca2+ stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning
10.1016/j.neuron.2006.11.024 · 2007 · External reference
The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: a potential therapeutic target (Review)
10.3892/ijmm.2017.2962 · 2017 · External reference
Mitogen-activated protein kinases in synaptic plasticity and memory
10.1016/j.conb.2004.04.001 · 2004 · External reference
Participation of hippocampal metabotropic glutamate receptors, protein kinase A and mitogen-activated protein kinases in memory retrieval
10.1016/s0306-4522(00)00236-0 · 2000 · External reference
Estrogen receptor beta-selective transcriptional activity and recruitment of coregulators by phytoestrogens
10.1074/jbc.m100953200 · 2001 · External reference
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
10.1038/353558a0 · 1991 · External reference
Morphological abnormalities in the brains of estrogen receptor beta knockout mice
10.1073/pnas.041617498 · 2001 · External reference
Multiple mechanisms of soy isoflavones against oxidative stress-induced endothelium injury
10.1016/j.freeradbiomed.2009.04.021 · 2009 · External reference
Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro
10.1080/01635589709514498 · 1997 · External reference
Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells
10.1002/mnfr.201200536 · 2013 · External reference
Active protection: Learning-activated Raf/MAPK activity protects labile memory from Rac1-independent forgetting
10.1016/j.neuron.2018.02.025 · 2018 · External reference
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the ‘two hit’ hypothesis
10.1016/s0047-6374(01)00342-6 · 2001 · External reference