Research graph
References from Comparison of effect of crush or transection peripheral nerve lesion on lumbar spinal cord synaptic plasticity and microglial dynamics. Local targets link to admitted publications; unresolved targets remain external evidence.
Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection
10.1038/s41598-017-14450-5 · 2017 · External reference
Mechanisms and consequences of microglial responses to peripheral axotomy
10.2741/192 · 2011 · External reference
Central neuron-glial and glial-glial interactions following axon injury
10.1016/s0301-0082(97)00093-2 · 1998 · External reference
Permanent central synaptic disconnection of proprioceptors after nerve injury and regeneration. I. Loss of VGLUT1/IA synapses on motoneurons
10.1152/jn.01095.2010 · 2011 · External reference
Activity dependent therapies modulate the spinal changes that motoneurons suffer after a peripheral nerve injury
10.1016/j.expneurol.2014.10.009 · 2015 · External reference
Cytokine pathways regulating glial and leukocyte function after spinal cord and peripheral nerve injury
10.1016/j.expneurol.2014.04.006 · 2014 · External reference
Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3
10.1016/j.expneurol.2012.06.008 · 2012 · External reference
Neuronal ‘On’ and ‘Off’ signals control microglia
10.1016/j.tins.2007.08.007 · 2007 · External reference
Displacement of synaptic terminals from regenerating motoneurons by microglial cells
10.1007/bf00325030 · 1968 · External reference
Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness
10.1007/s00213-016-4218-9 · 2016 · External reference
Heterogeneity of microglial activation in the innate immune response in the brain
10.1007/s11481-009-9164-4 · 2009 · External reference
Astrocyte reactivity influences the number of presynaptic terminals opposed to spinal motoneurons after axotomy
10.1016/j.brainres.2006.04.021 · 2006 · External reference
Spinal motoneuron synaptic plasticity after axotomy in the absence of inducible nitric oxide synthase
10.1186/1742-2094-7-31 · 2010 · External reference
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
10.1126/science.1194637 · 2010 · External reference
Microglial dynamics and role in the healthy and diseased brain: a paradigm of functional plasticity
10.1177/1073858414530512 · 2015 · External reference
Deficient functional recovery after facial nerve crush in rats is associated with restricted rearrangements of synaptic terminals in the facial nucleus
10.1016/j.neuroscience.2013.06.019 · 2013 · External reference
Functional indices for sciatic, peroneal, and posterior tibial nerve lesions in the mouse
10.1002/(sici)1098-2752(1998)18:2<119::aid-micr10>3.0.co;2-0 · 1998 · External reference
Cortical and subcortical contributions to activity-dependent plasticity in primate somatosensory cortex
10.1146/annurev.neuro.23.1.1 · 2000 · External reference
How dependent is synaptic plasticity on microglial phenotype?
10.1016/j.neuropharm.2014.08.012 · 2015 · External reference
Spinal versus brain microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain
10.1016/j.bbi.2016.05.021 · 2016 · External reference
Inhibition of spinal microglia and astrocytes contributes to the anti-allodynic effect of electroacupuncture in neuropathic pain induced by spinal nerve ligation
10.1136/acupmed-2015-010773 · 2016 · External reference
Expression of iNOS, CD163 and ARG-1 taken as M1 and M2 markers of microglial polarization in human glioblastoma and the surrounding normal parenchyma
10.1016/j.neulet.2017.02.076 · 2017 · External reference
Microglia activation states and cannabinoid system: therapeutic implications
10.1016/j.pharmthera.2016.06.011 · 2016 · External reference
Neural plasticity after peripheral nerve injury and regeneration
10.1016/j.pneurobio.2007.06.005 · 2007 · External reference
Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII
10.1074/jbc.m611907200 · 2007 · External reference
Microglial M1/M2 polarization and metabolic states
10.1111/bph.13139 · 2016 · External reference
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain
10.1155/2014/762930 · 2014 · External reference
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
10.1038/nn.2923 · 2011 · External reference
Ganglioside 9-O-acetyl GD3 expression is upregulated in the regenerating peripheral nerve
10.1016/j.neuroscience.2007.03.046 · 2007 · External reference
Mice lacking GD3 synthase display morphological abnormalities in the sciatic nerve and neuronal disturbances during peripheral nerve regeneration
10.1371/journal.pone.0108919 · 2014 · External reference
Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model
10.1016/j.jneuroim.2014.09.020 · 2014 · External reference
Spinal motor circuit synaptic plasticity after peripheral nerve injury depends on microglia activation and a CCR2 mechanism
2019 · External reference
Microglia dynamics and interactions with motoneurons axotomized after nerve injuries revealed by two-photon imaging
10.1038/s41598-020-65363-9 · 2020 · External reference
Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
10.1186/s12974-015-0431-4 · 2015 · External reference
VGLUT1 synapses and P-boutons on regenerating motoneurons after nerve crush
10.1002/cne.24244 · 2017 · External reference
Three types of nerve injury
10.1093/brain/66.4.237 · 1943 · External reference
Neuroprotective effects of mesenchymal stem cells on spinal motoneurons following ventral root axotomy: synapse stability and axonal regeneration
10.1016/j.neuroscience.2013.07.043 · 2013 · External reference
Aging microglia-phenotypes, functions and implications for age-related neurodegenerative diseases
10.3389/fnagi.2017.00194 · 2017 · External reference
The classical complement cascade mediates CNS synapse elimination
10.1016/j.cell.2007.10.036 · 2007 · External reference
Microglial subtypes: diversity within the microglial community
10.15252/embj.2019101997 · 2019 · External reference
Differential expression of synaptoporin and synaptophysin in primary sensory neurons and up-regulation of synaptoporin after peripheral nerve injury
10.1016/j.neuroscience.2006.05.010 · 2006 · External reference
A classification of peripheral nerve injures producing loss of function
10.1093/brain/74.4.491 · 1951 · External reference
Synaptic density of axotomized hypoglossal motorneurons following pharmacological blockade of the microglial cell proliferation
10.1006/exnr.1993.1046 · 1993 · External reference
Use of integrated optical clearing and 2-photon imaging to investigate sex differences in neuroimmune interactions after peripheral nerve injury
10.3389/fcell.2021.624201 · 2021 · External reference
Differential changes in neuronal excitability in the spinal dorsal horn after spinal nerve ligation in rats
10.1007/s11064-016-2003-0 · 2016 · External reference
Neurotrophins 3 and 4 differentially regulate NCAM, L1 and N-cadherin expression during peripheral nerve regeneration
10.1042/ba20070040 · 2008 · External reference
Evidence for synaptic stripping by cortical microglia
10.1002/glia.20462 · 2007 · External reference
Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression
10.1038/ncomms5294 · 2014 · External reference
Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
10.1523/jneurosci.4363-08.2009 · 2009 · External reference
Dynamic structural remodelling of microglia in health and disease: a review of the models, the signals and the mechanisms
10.1016/j.bbi.2013.12.010 · 2014 · External reference
Functional reorganization in somatosensory cortical areas 3b and 1 of adult monkeys after median nerve repair: possible relationships to sensory recovery in humans
10.1523/jneurosci.06-01-00218.1986 · 1986 · External reference
Minocycline inhibits brain inflammation and attenuates spontaneous recurrent seizures following pilocarpine-induced status epilepticus
10.1016/j.neuroscience.2014.12.021 · 2015 · External reference
Sexual dimorphism of microglia and synapses during mouse postnatal development
10.1002/dneu.22568 · 2018 · External reference
Plasticity from muscle to brain
10.1016/j.pneurobio.2006.03.001 · 2006 · External reference
Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy
10.1002/cne.903600109 · 1995 · External reference
Fine-tuning the central nervous system: microglial modelling of cells and synapses
10.1098/rstb.2013.0593 · 2014 · External reference
Spared nerve injury increases the expression of microglia M1 markers in the prefrontal cortex of rats and provokes depression-like behaviors
10.3389/fnins.2017.00209 · 2017 · External reference
Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis
10.1002/cne.23228 · 2013 · External reference
Quantifying microglia morphology from photomicrographs of immunohistochemistry prepared tissue using ImageJ
2018 · External reference
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia
10.1073/pnas.95.26.15769 · 1998 · External reference
Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse
2008 · External reference
SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury
10.1002/cne.22186 · 2009 · External reference