Research graph
References from Prolonged efavirenz exposure reduces peripheral oxytocin and vasopressin comparable to known drugs of addiction in male Sprague Dawley rats. Local targets link to admitted publications; unresolved targets remain external evidence.
The neurocircuitry involved in oxytocin modulation of methamphetamine addiction
2016 · External reference
Chronic methamphetamine self-administration dysregulates oxytocin plasma levels and oxytocin receptor fibre density in the nucleus accumbens core and subthalamic nucleus of the rat
10.1111/jne.12337 · 2016 · External reference
Dopamine and oxytocin interactions underlying behaviors: potential contributions to behavioral disorders
10.1111/j.1755-5949.2010.00154.x · 2010 · External reference
The role of the vasopressin system and dopamine D1 receptors in the effects of social housing condition on morphine reward
10.1016/j.drugalcdep.2018.03.021 · 2018 · External reference
Sex differences in animal models: focus on addiction
10.1124/pr.115.011163 · 2016 · External reference
Rebalancing the addicted brain: oxytocin interference with the neural substrates of addiction
10.1016/j.tins.2017.10.003 · 2017 · External reference
Increasing use of ‘party drugs’ in people living with HIV on antiretrovirals: a concern for patient safety
10.1097/qad.0000000000000786 · 2015 · External reference
Δ 9-Tetrahydrocannabinol-induced conditioned place preference and intracerebroventricular self-administration in rats
10.1016/j.ejphar.2004.10.043 · 2004 · External reference
Individual differences underlying susceptibility to addiction: role for the endogenous oxytocin system
10.1016/j.pbb.2013.09.005 · 2014 · External reference
CB 1 receptor signaling in the brain: extracting specificity from ubiquity
10.1038/npp.2017.206 · 2018 · External reference
Chronic exposure to Δ 9-tetrahydrocannabinol downregulates oxytocin and oxytocin-associated neurophysin in specific brain areas
10.1016/j.mcn.2006.01.008 · 2006 · External reference
Stimulant abuse: pharmacology, cocaine, methamphetamine, treatment, attempts at pharmacotherapy
10.1016/j.pop.2010.11.004 · 2011 · External reference
A review of the clinical pharmacology of methamphetamine
10.1111/j.1360-0443.2009.02564.x · 2009 · External reference
Molecular mechanisms of serotonergic action of the HIV-1 antiretroviral efavirenz
10.1016/j.phrs.2016.04.028 · 2016 · External reference
Adverse neuropsychiatric events and recreational use of efavirenz and other HIV-1 antiretroviral drugs
10.1124/pr.117.013706 · 2018 · External reference
Central nervous system penetration of antiretroviral drugs: pharmacokinetic, pharmacodynamic and pharmacogenomic considerations
10.1007/s40262-015-0257-3 · 2015 · External reference
Understanding the profile of a Nyaope addict and its connotations for law enforcement agencies
2017 · External reference
Rodent models in neuroscience research: is it a rat race?
10.1242/dmm.026120 · 2016 · External reference
Acute cocaine alters oxytocin levels in the medial preoptic area and amygdala in lactating rat dams: implications for cocaine-induced changes in maternal behavior and maternal aggression
10.1054/npep.2001.0854 · 2001 · External reference
Inhibition of monoamine oxidase activity by cannabinoids
10.1007/s00210-010-0517-6 · 2010 · External reference
The HIV antiretroviral drug efavirenz has LSD-like properties
10.1038/npp.2013.135 · 2013 · External reference
Cocaine abstinence induces emotional impairment and brain region-specific upregulation of the oxytocin receptor binding
10.1111/ejn.13348 · 2016 · External reference
Effects of alcohol and psychostimulants on the vasopressin system: behavioral implications
10.1111/jne.12611 · 2018 · External reference
Plasma vasopressin and interpersonal functioning
10.1016/j.biopsycho.2012.07.003 · 2012 · External reference
Whoonga: potential recreational use of HIV antiretroviral medication in South Africa
10.1007/s10461-013-0575-0 · 2014 · External reference
Different oxytocin responses to acute methamphetamine treatment in juvenile female rats perinatally exposed to stress and/or methamphetamine administration
10.3389/fphys.2019.00305 · 2019 · External reference
Methamphetamine consumption inhibits pair bonding and hypothalamic oxytocin in prairie voles
10.1371/journal.pone.0158178 · 2016 · External reference
The dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites
10.1016/j.neuropharm.2017.04.038 · 2017 · External reference
Acute cocaine treatment decreases oxytocin levels in the rat hippocampus
10.1016/0143-4179(93)90081-k · 1993 · External reference
Chronic cocaine treatment alters social/aggressive behavior in Sprague-Dawley rat dams and in their prenatally exposed offspring
10.1111/j.1749-6632.1998.tb09765.x · 1998 · External reference
Effects of chronic and intermittent cocaine treatment on dominance, aggression, and oxytocin levels in post-lactational rats
2010 · External reference
Methamphetamine and cardiovascular pathology: a review of the evidence
10.1111/j.1360-0443.2007.01874.x · 2007 · External reference
Cannabinoid receptors in the central nervous system: their signaling and roles in disease
2016 · External reference
Animal research: reporting in vivo experiments: the ARRIVE guidelines
10.1111/j.1476-5381.2010.00872.x · 2010 · External reference
Evolution of oxytocin pathways in the brain of vertebrates
10.3389/fnbeh.2014.00031 · 2014 · External reference
Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs
2013 · External reference
Targeting the oxytocin system to treat addictive disorders: rationale and progress to date
10.1007/s40263-016-0313-z · 2016 · External reference
Intranasal oxytocin: myths and delusions
10.1016/j.biopsych.2015.05.003 · 2016 · External reference
Oxytocin and rodent models of addiction
10.1016/bs.irn.2018.07.007 · 2018 · External reference
Deficits in plasma oxytocin responses and increased negative affect, stress, and blood pressure in mothers with cocaine exposure during pregnancy
10.1016/j.addbeh.2004.02.062 · 2004 · External reference
Delta(9)-Tetrahydrocannabinol-induced desensitization of cannabinoid-mediated inhibition of synaptic transmission between hippocampal neurons in culture
10.1016/j.neuropharm.2005.07.012 · 2005 · External reference
Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
10.1016/j.pbb.2007.06.002 · 2007 · External reference
Intergenerational effects of cocaine on maternal aggressive behavior and brain oxytocin in rat dams
10.1080/10253890701850239 · 2008 · External reference
Efavirenz exposure, alone and in combination with known drugs of abuse, engenders addictive-like bio-behavioural changes in rats
2018 · External reference
Unresolved reference
External reference
Cannabinoid Conditioned Reward and Aversion: Behavioral and Neural Processes
10.1021/cn100005p · 2010 · External reference
Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors
10.1016/j.tins.2012.08.004 · 2012 · External reference
Stress increases oxytocin release within the hypothalamic paraventricular nucleus
1998 · External reference
Region and context-specific intracellular responses associated with cocaine-induced conditioned place preference expression
10.1016/j.neuroscience.2014.12.010 · 2015 · External reference
Oxytocin receptors are expressed on dopamine and glutamate neurons in the mouse ventral tegmental area that project to nucleus accumbens and other mesolimbic targets
10.1002/cne.24116 · 2017 · External reference
Oxytocin buffers cortisol responses to stress in individuals with impaired emotion regulation abilities
10.1016/j.psyneuen.2010.12.005 · 2011 · External reference
Alcohol and endocannabinoids: neuroendocrine interactions in the reproductive axis
10.1016/j.expneurol.2010.03.019 · 2010 · External reference
Arginine vasopressin gene expression changes within the nucleus accumbens during environment elicited cocaine-conditioned response in rats
10.1016/j.neuropharm.2009.06.040 · 2010 · External reference
Whoonga and the abuse and diversion of antiretrovirals in Soweto, South Africa
10.1007/s10461-013-0683-x · 2014 · External reference
Unresolved reference
1999 · External reference
Oxytocin modulates behavioural adaptation to repeated treatment with cocaine in rats
10.1016/0028-3908(92)90192-r · 1992 · External reference
Effects of cocaine on the contents of neurohypophyseal hormones in the plasma and in different brain structures in rats
10.1016/0143-4179(92)90006-i · 1992 · External reference
Plasma oxytocin levels and anxiety in patients with major depression
10.1016/j.psyneuen.2007.01.009 · 2007 · External reference
Long-lasting effects of fluoxetine and/or exercise augmentation on bio-behavioural markers of depression in pre-pubertal stress sensitive rats
2017 · External reference
Cocaine: Usage, Misuse, and Addiction Processes. An Overview
2016 · External reference
Effect of high fat diets on body mass, oleylethanolamide plasma levels and oxytocin expression in growing rats
10.1111/1750-3841.12890 · 2015 · External reference
Characterizing the cognitive effects of cocaine: a comprehensive review
10.1016/j.neubiorev.2013.07.003 · 2013 · External reference
Neuromodulation by oxytocin and vasopressin
10.1016/j.neuron.2012.09.025 · 2012 · External reference
A conditioned place preference protocol for measuring incubation of craving in rats
10.3791/58384 · 2018 · External reference
Endocannabinoid Regulation of Neuroendocrine Systems
2015 · External reference
Administration of substances to laboratory animals: Routes of administration and factors to consider
2011 · External reference
The neurobiology of addiction
2019 · External reference
Influence of extra virgin olive oil on blood pressure and kidney angiotensinase activities in spontaneously hypertensive rats
2015 · External reference
Unresolved reference
2015 · External reference
Prenatal and gestational cocaine exposure: Effects on the oxytocin system and social behavior with implications for addiction
10.1016/j.pbb.2013.07.004 · 2014 · External reference
Chronic cocaine exposure during pregnancy increases postpartum neuroendocrine stress responses
10.1111/j.1365-2826.2012.02291.x · 2012 · External reference
The effects of 4-methylethcathinone on conditioned place preference, locomotor sensitization, and anxiety-like behavior: a comparison with methamphetamine
2016 · External reference
Oxytocin and opioid addiction revisited: old drug, new applications
10.1111/bph.13757 · 2018 · External reference
Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism
10.1016/j.pbb.2013.05.009 · 2014 · External reference
Methamphetamine and the hypothalamic-pituitary-adrenal axis
10.3389/fnins.2015.00178 · 2015 · External reference
