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References from Mid-pregnancy maternal immune activation increases Pax6-positive and Tbr2-positive neural progenitor cells and causes integrated stress response in the fetal brain in a mouse model of maternal viral infection. Local targets link to admitted publications; unresolved targets remain external evidence.
The unfolded protein response: a key player in Zika virus-associated congenital microcephaly
10.3389/fncel.2019.00094 · 2019 · External reference
Neural stem and progenitor cells shorten S-phase on commitment to neuron production
10.1038/ncomms1155 · 2011 · External reference
Association of family history of autoimmune diseases and autism spectrum disorders
10.1542/peds.2008-2445 · 2009 · External reference
QuPath: open source software for digital pathology image analysis
10.1038/s41598-017-17204-5 · 2017 · External reference
"Females Are Not Just 'Protected' Males": sex-specific vulnerabilities in placenta and brain after prenatal immune disruption
10.1523/eneuro.0358-19.2019 · 2019 · External reference
Prenatal rubella, premorbid abnormalities, and adult schizophrenia
10.1016/s0006-3223(01)01068-x · 2001 · External reference
Serologic evidence of prenatal influenza in the etiology of schizophrenia
10.1001/archpsyc.61.8.774 · 2004 · External reference
Prenatal infection as a risk factor for schizophrenia
10.1093/schbul/sbj052 · 2006 · External reference
Endoplasmic reticulum stress, inflammation, and perinatal brain damage
10.1203/pdr.0b013e3181baa083 · 2009 · External reference
Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons
10.1038/mp.2015.222 · 2016 · External reference
Placental TNF-α signaling in illness-induced complications of pregnancy
10.1016/j.ajpath.2011.02.042 · 2011 · External reference
Stereotypical alterations in cortical patterning are associated with maternal illness-induced placental dysfunction
10.1523/jneurosci.4654-12.2013 · 2013 · External reference
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
10.1126/science.aad0314 · 2016 · External reference
Neuron number and size in prefrontal cortex of children with autism
10.1001/jama.2011.1638 · 2011 · External reference
Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex
10.1523/jneurosci.2899-04.2005 · 2005 · External reference
Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis
10.1074/jbc.m110.140699 · 2010 · External reference
Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway
10.1016/j.stem.2013.10.002 · 2013 · External reference
Effects of maternal immune activation on gene expression patterns in the fetal brain
10.1038/tp.2012.24 · 2012 · External reference
ShinyGO: a graphical gene-set enrichment tool for animals and plants
10.1093/bioinformatics/btz931 · 2020 · External reference
Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity
10.3389/fncel.2017.00359 · 2017 · External reference
Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly
10.1038/s41593-017-0038-4 · 2018 · External reference
Emerging roles for the unfolded protein response in the developing nervous system
10.1016/j.tins.2016.04.002 · 2016 · External reference
The cell biology of neurogenesis
10.1038/nrm1739 · 2005 · External reference
The spectrum of structural and functional network alterations in malformations of cortical development
10.1093/brain/awx145 · 2017 · External reference
Activation of the maternal immune system induces endocrine changes in the placenta via IL-6
10.1016/j.bbi.2010.12.017 · 2011 · External reference
Maternal immune activation in mice disrupts proteostasis in the fetal brain
10.1038/s41593-020-00762-9 · 2021 · External reference
Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring
10.1016/j.bbi.2019.09.011 · 2020 · External reference
A dynamic unfolded protein response contributes to the control of cortical neurogenesis
10.1016/j.devcel.2015.11.005 · 2015 · External reference
Heat shock alters the expression of schizophrenia and autism candidate genes in an induced pluripotent stem cell model of the human telencephalon
10.1371/journal.pone.0094968 · 2014 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
10.1006/meth.2001.1262 · 2001 · External reference
The integrated stress response
10.15252/embr.201642195 · 2016 · External reference
Regulation of radial glial survival by signals from the meninges
10.1523/jneurosci.5537-08.2009 · 2009 · External reference
Cell cycle control of mammalian neural stem cells: putting a speed limit on G1
10.1016/j.tcb.2010.01.006 · 2010 · External reference
Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus
10.1016/j.ijdevneu.2004.05.005 · 2005 · External reference
Reversing behavioural abnormalities in mice exposed to maternal inflammation
10.1038/nature23909 · 2017 · External reference
Maternal immune activation alters fetal brain development through interleukin-6
10.1523/jneurosci.2178-07.2007 · 2007 · External reference
Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse
10.1093/brain/awr237 · 2011 · External reference
Patches of disorganization in the neocortex of children with autism
10.1056/nejmoa1307491 · 2014 · External reference
Molecular mechanisms underlying the models of neurodevelopmental disorders in maternal immune activation relevant to the placenta
2018 · External reference
The suppression of maternal-fetal leukemia inhibitory factor signal relay pathway by maternal immune activation impairs brain development in mice
10.1371/journal.pone.0129011 · 2015 · External reference
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes
10.1007/s00401-010-0655-4 · 2010 · External reference
The placental interleukin-6 signaling controls fetal brain development and behavior
10.1016/j.bbi.2016.11.007 · 2017 · External reference