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References from HOP protein expression in the hippocampal dentate gyrus is acutely downregulated in a status epilepticus mouse model. Local targets link to admitted publications; unresolved targets remain external evidence.
A common embryonic origin of stem cells drives developmental and adult neurogenesis
10.1016/j.cell.2019.02.010 · 2019 · External reference
Status epilepticus in adults
2015 · External reference
Temporal lobe epilepsy semiology
10.1155/2012/751510 · 2012 · External reference
International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods
10.1111/epi.12220 · 2013 · External reference
Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain
10.1046/j.1460-9568.2003.02567.x · 2003 · External reference
Hop is an unusual homeobox gene that modulates cardiac development
10.1016/s0092-8674(02)00932-7 · 2002 · External reference
Status epilepticus
2009 · External reference
Incidence, cause, and short-term outcome of convulsive status epilepticus in childhood: prospective population-based study
10.1016/s0140-6736(06)69043-0 · 2006 · External reference
Quantitative MRI predicts status epilepticus-induced hippocampal injury in the lithium-pilocarpine rat model
10.1016/j.eplepsyres.2009.11.013 · 2010 · External reference
Inflammatory processes, febrile seizures, and subsequent epileptogenesis
10.5698/1535-7511-14.s2.15 · 2014 · External reference
Epilepsy and Neuron Loss in the Hippocampus
10.1111/j.1528-1157.1980.tb04315.x · 1980 · External reference
Adult neurogenesis in the development of epilepsy
10.1177/1535759719868186 · 2019 · External reference
A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia
10.1212/wnl.46.4.1029 · 1996 · External reference
Anti-Inflammatory Small Molecules to Treat Seizures and Epilepsy: From Bench to Bedside
2016 · External reference
Doublecortin (DCX) is not essential for survival and differentiation of newborn neurons in the adult mouse dentate gyrus
2016 · External reference
Prolonged inflammatory gene response following soman-induced seizures in mice
10.1016/j.tox.2007.05.032 · 2007 · External reference
RNA-seq analysis of hippocampal tissues reveals novel candidate genes for drug refractory epilepsy in patients with MTLE-HS
10.1016/j.ygeno.2016.04.001 · 2016 · External reference
Inflammation is detrimental for neurogenesis in adult brain
10.1073/pnas.2234031100 · 2003 · External reference
Mesial temporal lobe epilepsy: What have we learned
10.1177/107385840100700410 · 2001 · External reference
Transcriptional regulation of the cardiac conduction system
2020 · External reference
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation
10.1016/j.stem.2018.09.009 · 2018 · External reference
Early Seizure activity accelerates depletion of hippocampal neural stem cells and impairs spatial discrimination in an Alzheimer’s disease model
10.1016/j.celrep.2019.05.101 · 2019 · External reference
Mesial temporal sclerosis: pathogenesis, diagnosis, and management
10.1111/j.1528-1157.1990.tb05860.x · 1990 · External reference
Homeodomain proteins
1994 · External reference
Neurons induce GFAP gene promoter of cultured astrocytes from transgenic mice
10.1002/(sici)1098-1136(199904)26:2<97::aid-glia1>3.0.co;2-z · 1999 · External reference
Overexpression of the neurotrophic cytokine S100β in human temporal lobe epilepsy
10.1046/j.1471-4159.1995.65010228.x · 1995 · External reference
Rapamycin attenuates acute seizure-induced astrocyte injury in mice in vivo
2017 · External reference
Brain lipid-binding protein promotes proliferation and modulates cell cycle in C6 rat glioma cells
10.3892/ijo.2017.4132 · 2017 · External reference
Specification of the cardiac conduction system by transcription factors
2009 · External reference
HOPX regulates bone marrow-derived mesenchymal stromal cell fate determination via suppression of adipogenic gene pathways
10.1038/s41598-020-68261-2 · 2020 · External reference
Effects of an acute seizure on associative learning and memory
10.1016/j.yebeh.2015.11.001 · 2016 · External reference
Intrinsic astrocyte heterogeneity influences tumor growth in Glioma Mouse Models
10.1111/bpa.12348 · 2017 · External reference
Homeobox protein Hop functions in the adult cardiac conduction system
10.1161/01.res.0000163108.47258.f3 · 2005 · External reference
Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability
10.1016/j.neuron.2006.11.004 · 2006 · External reference
Epilepsy and adult neurogenesis
2015 · External reference
Peripherally induced tolerance depends on peripheral regulatory T cells that require Hopx to inhibit intrinsic IL-2 expression
10.4049/jimmunol.1500174 · 2015 · External reference
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis
10.1016/s0165-0270(02)00007-9 · 2002 · External reference
BLBP-expression in astrocytes during experimental demyelination and in human multiple sclerosis lesions
10.1016/j.bbi.2011.05.003 · 2011 · External reference
Histopathology of human epilepsy
10.1111/j.1528-1167.2010.02823.x · 2010 · External reference
Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments (cDNA expression library/cytoskeleton/astrocytes)
10.1073/pnas.81.9.2743 · 1984 · External reference
Doublecortin-expressing cell types in temporal lobe epilepsy
10.1186/s40478-018-0566-5 · 2018 · External reference
Hopx distinguishes hippocampal from lateral ventricle neural stem cells
10.1016/j.scr.2015.09.015 · 2015 · External reference
Neuronal injury, gliosis, and glial proliferation in two models of temporal lobe epilepsy
10.1093/jnen/nlw008 · 2016 · External reference
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging
10.1016/j.stem.2010.03.017 · 2010 · External reference
Recognition memory is impaired in children after prolonged febrile seizures
10.1093/brain/aws213 · 2012 · External reference
Role of radial glia in cytogenesis, patterning and boundary formation in the developing spinal cord
2005 · External reference
Homeobox genes and axial patterning
10.1016/0092-8674(92)90471-n · 1992 · External reference
Evidence that doublecortin is dispensable for the development of adult born neurons in mice
10.1371/journal.pone.0062693 · 2013 · External reference
Adult neurogenesis in the Mammalian Brain: significant answers and significant questions
10.1016/j.neuron.2011.05.001 · 2011 · External reference
Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures
10.1073/pnas.0801372105 · 2008 · External reference
Microglial P2Y12 receptor regulates seizure-induced neurogenesis and immature neuronal projections
10.1523/jneurosci.0487-19.2019 · 2019 · External reference
A roof plate-dependent enhancer controls the expression of Homeodomain only protein in the developing cerebral cortex
10.1016/j.ydbio.2005.04.033 · 2005 · External reference
Prox 1, a prospero-related homeobox gene expressed during mouse development
10.1016/0925-4773(93)90012-m · 1993 · External reference
Altered emotional behavioral responses in mice lacking brain-type fatty acid-binding protein gene
10.1111/j.1460-9568.2006.04855.x · 2006 · External reference
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat
10.1016/0006-8993(71)90358-1 · 1971 · External reference
Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
10.1523/jneurosci.17-10-03727.1997 · 1997 · External reference
Modification of seizure activity by electrical stimulation: II. Motor seizure
10.1016/0013-4694(72)90177-0 · 1972 · External reference
The role of inflammation in the development of epilepsy
2018 · External reference
S100B expression defines a state in which GFAP-expressing cells lose their neural stem cell potential and acquire a more mature developmental stage
10.1002/glia.20445 · 2007 · External reference
Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3
10.1161/circresaha.111.260695 · 2012 · External reference
Reactive astrogliosis causes the development of spontaneous seizures
10.1523/jneurosci.1574-14.2015 · 2015 · External reference
Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression
2016 · External reference
Epileptogenesis in the parahippocampal region. Parallels with the dentate gyrus
2000 · External reference
Hippocampal abnormalities after prolonged febrile convulsion: a longitudinal MRI study
10.1093/brain/awg262 · 2003 · External reference
Rapid astrocyte and microglial activation following pilocarpine-induced seizures in rats
2008 · External reference
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein
10.1016/s0092-8674(02)00933-9 · 2002 · External reference
Molecular dissection of reactive astrogliosis and glial scar formation
10.1016/j.tins.2009.08.002 · 2009 · External reference
A transgenic mouse model for the detailed morphological study of astrocytes
10.1016/j.neures.2003.08.008 · 2003 · External reference
Mesial temporal lobe epilepsy
10.1097/wnp.0b013e31826b3ab7 · 2012 · External reference
Monitoring the neuroinflammatory response following acute brain injury
2017 · External reference
Temporal lobe sclerosis associated with hippocampal sclerosis in temporal lobe epilepsy: neuropathological features
10.1097/nen.0b013e3181b05d67 · 2009 · External reference
Brain lipid binding protein mediates the proliferation of human glioblastoma cells by regulating ERK1/2 signaling pathway in vitro
10.1007/s11626-017-0220-8 · 2018 · External reference
10.1186/1749-8104-3-13
10.1186/1749-8104-3-13 · External reference
Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study
10.1016/0166-4328(83)90136-5 · 1983 · External reference
Targeting Seizure-induced neurogenesis in a clinically relevant time period leads to transient but not persistent seizure reduction
10.1523/jneurosci.0920-19.2019 · 2019 · External reference
Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin
10.1093/brain/awm264 · 2007 · External reference
Infections, inflammation and epilepsy
2016 · External reference
The appropriate marker for astrocytes: comparing the distribution and expression of three astrocytic markers in different mouse cerebral regions
2019 · External reference
Evidence for inflammation as a driver of atrial fibrillation
10.3389/fcvm.2020.00062 · 2020 · External reference
HOPX defines heterogeneity of postnatal subventricular zone neural stem cells
10.1016/j.stemcr.2018.08.006 · 2018 · External reference
