Research graph
References from Childhood trauma and genetic variation in the DAT 40-bp VNTR contribute to HIV-associated neurocognitive disorders. Local targets link to admitted publications; unresolved targets remain external evidence.
Cerebrospinal fluid biomarkers and HIV-associated neurocognitive disorders in HIV-infected individuals in Rakai, Uganda
10.1007/s13365-016-0505-9 · 2017 · External reference
Gender-based violence and HIV: relevance for HIV prevention in hyperendemic countries of southern Africa
10.1097/01.aids.0000341778.73038.86 · 2008 · External reference
Updated research nosology for HIV-associated neurocognitive disorders
10.1212/01.wnl.0000287431.88658.8b · 2007 · External reference
Effect of human immunodeficiency virus on blood-brain barrier integrity and function: an update
10.3389/fncel.2015.00212 · 2015 · External reference
What does dopamine mean?
10.1038/s41593-018-0152-y · 2018 · External reference
Development and validation of a brief screening version of the childhood trauma questionnaire
10.1016/s0145-2134(02)00541-0 · 2003 · External reference
Impact of COMT Val158Met on executive functioning in the context of HIV and methamphetamine
10.2147/nbhiv.s8245 · 2010 · External reference
Impact of the COMT Val108/158 Met and DAT genotypes on prefrontal function in healthy subjects
10.1016/j.neuroimage.2007.06.021 · 2007 · External reference
Functional connectivity in virally suppressed patients with hiv-associated neurocognitive disorder: a resting-state analysis
10.3174/ajnr.a5246 · 2017 · External reference
Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse
10.1016/j.neuroimage.2008.05.011 · 2008 · External reference
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain
10.1086/425589 · 2004 · External reference
Maladaptive coping mediates the influence of childhood trauma on depression and PTSD among pregnant women in South Africa
10.1007/s00737-015-0501-8 · 2015 · External reference
Analysis of DRD4 and DAT polymorphisms and behavioral inhibition in healthy adults: implications for impulsivity
10.1002/ajmg.b.30557 · 2008 · External reference
Serotonin and dopamine: unifying affective, activational, and decision functions
10.1038/npp.2010.121 · 2011 · External reference
Association of the dopamine transporter (DAT1) 10/10-repeat genotype with ADHD symptoms and response inhibition in a general population sample
10.1038/sj.mp.4001641 · 2005 · External reference
Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid
10.1097/00002030-200009080-00010 · 2000 · External reference
Posttraumatic stress disorder and neurocognitive impairment in a U.S. military cohort of persons living with HIV
2019 · External reference
10.1080/20008198.2017.1394146
10.1080/20008198.2017.1394146 · External reference
Cortical synaptic density is reduced in mild to moderate human immunodeficiency virus neurocognitive disorder
10.1111/j.1750-3639.1999.tb00219.x · 1999 · External reference
‘Regulation of firing of dopaminergic neurons and control of goal-directed behaviors’
10.1016/j.tins.2007.03.003 · 2007 · External reference
Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline
10.1212/wnl.0000000000000492 · 2014 · External reference
Sustained High HIV Incidence in Young Women in Southern Africa: Social, Behavioral and Structural Factors and Emerging Intervention Approaches
10.1007/s11904-015-0261-0 · 2015 · External reference
Neurobehavioral effects of human immunodeficiency virus infection among former plasma donors in rural China
10.1080/13550280802378880 · 2008 · External reference
HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
10.1007/s13365-010-0006-1 · 2011 · External reference
Genotype influences in vivo dopamine transporter availability in human striatum
10.1016/s0893-133x(99)00099-8 · 2000 · External reference
Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
10.1016/j.bbi.2014.10.008 · 2015 · External reference
Increases in CSF dopamine in HIV patients are due to the dopamine transporter 10/10-repeat allele which is more frequent in HIV-infected individuals
10.1007/s00702-013-1086-x · 2013 · External reference
The dopamine-related polymorphisms BDNF, COMT, DRD2, DRD3, and DRD4 are not linked with changes in CSF dopamine levels and frequency of HIV infection
10.1007/s00702-016-1659-6 · 2017 · External reference
Prevalence of emotional, physical and sexual abuse of women in three South African provinces
2001 · External reference
Rape of girls in South Africa
10.1016/s0140-6736(02)07530-x · 2002 · External reference
Sexual assault history and risks for sexually transmitted infections among women in an African township in Cape Town, South Africa
10.1080/09540120410331269530 · 2004 · External reference
CSF Viral Escape in a patient with HIV-Associated Neurocognitive Disorder
10.1007/s13365-013-0175-9 · 2013 · External reference
HIV disease progression: depression, stress, and possible mechanisms
10.1016/s0006-3223(03)00323-8 · 2003 · External reference
Role of depression, stress, and trauma in HIV disease progression
10.1097/psy.0b013e3181777a5f · 2008 · External reference
Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults
10.1080/13803395.2011.623118 · 2012 · External reference
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition
10.1176/appi.ajp.159.4.652 · 2002 · External reference
Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART)
10.1136/jnnp.69.3.376 · 2000 · External reference
Differential COMT expression and behavioral effects of COMT inhibition in male and female Wistar and alcohol preferring rats
10.1016/j.alcohol.2017.08.007 · 2018 · External reference
Mesolimbic dopamine function is related to salience network connectivity: an integrative positron emission tomography and magnetic resonance study
10.1016/j.biopsych.2018.09.010 · 2019 · External reference
Expression of the dopamine transporter gene is regulated by the 3’ UTR VNTR: Evidence from brain and lymphocytes using quantitative RT-PCR
10.1002/ajmg.b.10948 · 2002 · External reference
Dopamine and the regulation of cognition and attention
10.1016/s0301-0082(02)00011-4 · 2002 · External reference
Controversies in HIV-associated neurocognitive disorders
10.1016/s1474-4422(14)70137-1 · 2014 · External reference
Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation
10.1186/1742-2094-11-34 · 2014 · External reference
The relationship between stressful life events and cognitive function in HIV-infected men
10.1176/jnp.15.4.436 · 2003 · External reference
Catecholamine metabolism in the brain by membrane-bound and soluble catechol-o-methyltransferase (COMT) estimated by enzyme kinetic values
10.1054/mehy.2001.1430 · 2001 · External reference
Attention-deficit hyperactivity disorder: a study of association with both the dopamine transporter gene and the dopamine D4 receptor gene
10.1002/ajmg.1408 · 2001 · External reference
Changing clinical phenotypes of HIV-associated neurocognitive disorders
10.1007/s13365-017-0556-6 · 2018 · External reference
COMT Val158Met polymorphism, cardiometabolic risk, and nadir CD4 synergistically increase risk of neurocognitive impairment in men living with HIV
10.1097/qai.0000000000002083 · 2019 · External reference
Catechol-O-Methyltransferase (COMT) gene (Val158Met) and brain-derived neurotropic factor (BDNF) (Val66Met) genes polymorphism in schizophrenia: a case-control study
2017 · External reference
HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment
10.1038/nrneurol.2016.27 · 2016 · External reference
Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex
10.1038/mp.2017.126 · 2018 · External reference
Changes in cognitive function in women with HIV infection and early life stress
10.1080/09540121.2016.1204417 · 2017 · External reference
Effects of HIV and childhood trauma on brain morphometry and neurocognitive function
10.1007/s13365-015-0379-2 · 2016 · External reference
Genetic predictor of working memory and prefrontal function in women with HIV
10.1007/s13365-014-0305-z · 2015 · External reference
Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters
10.1111/j.1432-1033.1994.tb19083.x · 1994 · External reference
Pathways to neurodegeneration: effects of HIV and aging on resting-state functional connectivity
10.1212/wnl.0b013e318288792b · 2013 · External reference
Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest
10.1016/j.neuroimage.2012.11.059 · 2013 · External reference
Poly-Victimization in a National Sample of Children and Youth
10.1016/j.amepre.2009.11.012 · 2010 · External reference
The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density
10.1186/1471-2156-6-55 · 2005 · External reference
Decreased brain dopaminergic transporters in HIV-associated dementia patients
2004 · External reference
Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis
10.1212/wnl.0000000000010752 · 2020 · External reference
Childhood maltreatment and HIV-associated neurocognitive disorders share similar pathophysiology: a potential sensitisation mechanism?
10.1007/s11011-017-0062-9 · 2017 · External reference
Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum
10.1523/jneurosci.0665-07.2007 · 2007 · External reference
Reduced Dopamine Transporter Availability and Neurocognitive Deficits in Male Patients with Alcohol Dependence
10.1371/journal.pone.0131017 · 2015 · External reference
Beneficial and adverse effects of cART affect neurocognitive function in HIV-1 infection: balancing viral suppression against neuronal stress and injury
2019 · External reference
Unresolved reference
External reference
