Research graph
References from CaMKIIβ knockdown decreases store-operated calcium entry in hippocampal dendritic spines. Local targets link to admitted publications; unresolved targets remain external evidence.
Purification and characterization of a calmodulin-dependent protein kinase that is highly concentrated in brain
10.1016/s0021-9258(17)44239-6 · 1983 · External reference
Dendritic spines provide cognitive resilience against Alzheimer’s disease
10.1002/ana.25049 · 2017 · External reference
Do thin spines learn to be mushroom spines that remember?
10.1016/j.conb.2007.04.009 · 2007 · External reference
Pathogenesis and Disease-modifying Therapy in Alzheimer’s Disease: The Flat Line of Progress
10.1016/j.arcmed.2012.09.009 · 2012 · External reference
Antagonist of neuronal store-operated calcium entry exerts beneficial effects in neurons expressing PSEN1ΔE9 mutant linked to familial Alzheimer disease
10.1016/j.neuroscience.2019.04.043 · 2019 · External reference
Alzheimer’s disease: MRNA expression profiles of multiple patients show alterations of genes involved with calcium signaling
10.1016/j.nbd.2005.09.004 · 2006 · External reference
Selective regulation of neurite extension and synapse formation by the β but not the α isoform of CaMKII
10.1016/s0896-6273(03)00428-8 · 2003 · External reference
Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons
10.1371/journal.pone.0019285 · 2011 · External reference
Dendritic spine geometry: Functional implication and regulation
10.1016/j.neuron.2005.05.006 · 2005 · External reference
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines
10.1038/s41593-021-00874-w · 2021 · External reference
Calcium-calmodulin-dependent protein kinase II isoforms differentially impact the dynamics and structure of the actin cytoskeleton
10.1021/bi3016586 · 2013 · External reference
Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease
10.1073/pnas.91.2.534 · 1994 · External reference
Transient Receptor Potential Channel 6 (TRPC6) Protects Podocytes during Complement-mediated Glomerular Disease *
10.1074/jbc.m113.488122 · 2013 · External reference
Expression of STIM1 in brain and puncta-like co-localization of STIM1 and ORAI1 upon depletion of Ca2+ store in neurons
10.1016/j.neuint.2008.10.005 · 2009 · External reference
Calcium dyshomeostasis and intracellular signalling in alzheimer’s disease
10.1038/nrn960 · 2002 · External reference
CaMKII Potentiates Store-Operated Ca 2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1
10.1159/000488835 · 2018 · External reference
Dendritic EGFP-STIM1 activation after type I metabotropic glutamate and muscarinic acetylcholine receptor stimulation in hippocampal neuron
10.1002/jnr.22648 · 2011 · External reference
CaMKIIβ association with the actin cytoskeleton is regulated by alternative splicing
10.1091/mbc.e06-03-0252 · 2006 · External reference
The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure
10.1073/pnas.0701656104 · 2007 · External reference
Derivatives of Piperazines as Potential Therapeutic Agents for Alzheimer’s Disease
10.1124/mol.118.114348 · 2019 · External reference
Dysregulation of Intracellular Calcium Signaling in Alzheimer’s Disease
10.1089/ars.2018.7506 · 2018 · External reference
STIM2 protects hippocampal mushroom spines from amyloid synaptotoxicity
10.1186/s13024-015-0034-7 · 2015 · External reference
Synaptic tagging and capture: Differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation
10.1523/jneurosci.3140-09.2010 · 2010 · External reference
Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
10.1371/journal.pone.0001997 · 2008 · External reference
Pridopidine stabilizes mushroom spines in mouse models of Alzheimer’s disease by acting on the sigma-1 receptor
10.1016/j.nbd.2018.12.022 · 2019 · External reference
CaMKIIβ functions as an F-actin targeting module that localizes CaMKIIα/β heterooligomers to dendritic spines
10.1016/s0896-6273(00)80569-3 · 1998 · External reference
Molecular determinants for cardiovascular TRPC6 channel regulation by Ca 2+ /calmodulin-dependent kinase II. The Authors
2013 · External reference
Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells
10.1113/jphysiol.2004.075051 · 2004 · External reference
10.55782/ane-2009-1753
10.55782/ane-2009-1753 · External reference
Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice
10.1016/j.neuron.2014.02.019 · 2014 · External reference
The dysregulation of intracellular calcium in Alzheimer disease
2010 · External reference
Thin, stubby or mushroom: spine pathology in Alzheimers disease
10.2174/156720509788486554 · 2009 · External reference
Structural rearrangement of CaMKIIalpha catalytic domains encodes activation
10.1073/pnas.0901913106 · 2009 · External reference
α- and βCaMKII: Inverse regulation by neuronal activity and opposing effects on synaptic strength
10.1016/s0896-6273(02)01049-8 · 2002 · External reference
Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs
10.1016/s0021-9258(19)84658-6 · 1989 · External reference
KN-62, 1-[N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperaz ine, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II
10.1016/s0021-9258(19)39565-1 · 1990 · External reference
Spine neck plasticity regulates compartmentalization of synapses
10.1038/nn.3682 · 2014 · External reference
Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons
10.1523/jneurosci.5528-08.2009 · 2009 · External reference
Red fluorescent Xenopus laevis: a new tool for grafting analysis
10.1186/1471-213x-9-37 · 2009 · External reference
Neuronal store-operated calcium entry and mushroom spine loss in amyloid precursor protein knock-in mouse model of Alzheimer’s disease
10.1523/jneurosci.1034-15.2015 · 2015 · External reference
Store-operated calcium channel complex in postsynaptic spines: a new therapeutic target for Alzheimer’s disease treatment
10.1523/jneurosci.1188-16.2016 · 2016 · External reference
