References

Relationship between wheel running, feeding, drinking, and body weight in male rats

10.1016/s0031-9384(03)00216-6 · 2003 · External reference

Moderate-intensity physical exercise protects against experimental 6-hydroxydopamine-induced hemiparkinsonism through Nrf2-antioxidant response element pathway

10.1007/s11064-015-1709-8 · 2016 · External reference

Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice

10.1007/s12640-015-9566-4 · 2016 · External reference

Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice

10.1016/j.neuroscience.2013.03.039 · 2013 · External reference

Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats

10.1191/0960327105ht509oa · 2005 · External reference

Physical exercise attenuates MPTP-induced deficits in mice

10.1007/s12640-010-9168-0 · 2010 · External reference

The 6-OHDA mouse model of Parkinson’s disease - Terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain bundle lesions

10.1016/j.bbr.2015.03.058 · 2015 · External reference

Exercise-induced oxidative-nitrosative stress is associated with impaired dynamic cerebral autoregulation and blood-brain barrier leakage

10.1113/expphysiol.2011.060178 · 2011 · External reference

Prevention of cardiovascular diseases: role of exercise, dietary interventions, obesity and smoking cessation

2005 · External reference

Effects of olive leaf polyphenols on male mouse brain NGF, BDNF and their receptors TrkA, TrkB and p75

10.1080/14786419.2014.918977 · 2014 · External reference

Higher dietary anthocyanin and flavonol intakes are associated with anti-inflammatory effects in a population of US adults

10.3945/ajcn.115.108555 · 2015 · External reference

Quercetin enhances exercise-mediated neuroprotective effects in brain ischemic rats

10.1249/mss.0000000000000310 · 2014 · External reference

Neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease

10.1016/j.nbd.2005.12.008 · 2006 · External reference

Physical activity and the risk of Parkinson disease

10.1212/01.wnl.0000151960.28687.93 · 2005 · External reference

Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway

10.1016/j.neuroscience.2017.07.031 · 2017 · External reference

Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF

10.1046/j.1471-4159.2003.01657.x · 2003 · External reference

Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: time course of protection and neurorestoration

10.1016/j.brainres.2010.11.006 · 2011 · External reference

Effects of physical exercise programs on cognitive function in Parkinson's disease patients: A systematic review of randomized controlled trials of the last 10 years

2018 · External reference

Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease

10.1097/00001756-200112040-00053 · 2001 · External reference

Effects of olive polyphenols administration on nerve growth factor and brain-derived neurotrophic factor in the mouse brain

10.1016/j.nut.2012.11.007 · 2013 · External reference

Exercise improves motor deficits and alters striatal GFAP expression in a 6-OHDA-induced rat model of Parkinson’s disease

10.1007/s10072-011-0925-5 · 2012 · External reference

The effect of red grape juice and exercise, and their combination on parkinson(’)s disease in rats

2012 · External reference

BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog

10.1016/j.neurobiolaging.2010.03.019 · 2012 · External reference

Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia

10.1002/jnr.20162 · 2004 · External reference

Habitual intake of dietary flavonoids and risk of Parkinson disease

10.1212/wnl.0b013e31824f7fc4 · 2012 · External reference

Prospective study of dietary pattern and risk of Parkinson disease

10.1093/ajcn/86.5.1486 · 2007 · External reference

Exercise protects against MPTP-induced neurotoxicity in mice

10.1016/j.brainres.2010.01.053 · 2010 · External reference

The effectiveness of exercise interventions for people with Parkinson’s disease: a systematic review and meta-analysis

10.1002/mds.21922 · 2008 · External reference

Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway

10.1016/j.freeradbiomed.2005.04.022 · 2005 · External reference

Protective effects of green tea polyphenols in the 6-OHDA rat model of Parkinson’s disease through inhibition of ROS-NO pathway

10.1016/j.biopsych.2007.04.020 · 2007 · External reference

The discovery of dopamine deficiency in the parkinsonian brain

2006 · External reference

Stress reduces the neuroprotective effect of exercise in a rat model for Parkinson’s disease

10.1016/j.bbr.2005.06.044 · 2005 · External reference

Voluntary Physical Exercise Improves Subsequent Motor and Cognitive Impairments in a Rat Model of Parkinson’s Disease

2018 · External reference

Survey of antioxidant capacity and phenolic composition of blueberry, blackberry, and strawberry in Nanjing

10.1631/jzus.b1100137 · 2012 · External reference

Different effects of five catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells

10.1021/jf010903r · 2001 · External reference

Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson’s disease in rats

10.1016/j.ejphar.2008.10.005 · 2008 · External reference

Grape juice, berries, and walnuts affect brain aging and behavior

10.3945/jn.109.108266 · 2009 · External reference

Effects of diet and/or exercise in enhancing spinal cord sensorimotor learning

10.1371/journal.pone.0041288 · 2012 · External reference

Nutraceutical antioxidants as novel neuroprotective agents

10.3390/molecules15117792 · 2010 · External reference

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

10.1056/nejmoa1605086 · 2016 · External reference

Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections

10.1006/exnr.2000.7463 · 2000 · External reference

Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment

10.1017/s0007114509992364 · 2010 · External reference

Blueberry supplementation improves memory in older adults

10.1021/jf9029332 · 2010 · External reference

Combination of nutritional polyphenols supplementation with exercise training counteracts insulin resistance and improves endurance in high-fat diet-induced obese rats

10.1038/s41598-018-21287-z · 2018 · External reference

A comparison of voluntary and forced exercise in protecting against behavioral asymmetry in a juvenile hemiparkinsonian rat model

10.1016/j.bbr.2013.04.002 · 2013 · External reference

Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson’s disease with moderate neurodegeneration

10.1111/j.1460-9568.2011.07626.x · 2011 · External reference

Naringin protects the nigrostriatal dopaminergic projection through induction of GDNF in a neurotoxin model of Parkinson’s disease

10.1016/j.jnutbio.2014.03.006 · 2014 · External reference

Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration

10.1046/j.1471-4159.2001.00490.x · 2001 · External reference

Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures

10.1016/s0006-2952(01)00813-9 · 2002 · External reference

Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade

10.1016/j.neuroscience.2009.02.008 · 2009 · External reference

Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundle

10.1023/b:mebr.0000027416.13070.c3 · 2004 · External reference

Effect of exercise on dopamine neuron survival in prenatally stressed rats

10.1007/s11011-009-9161-6 · 2009 · External reference

Physical activity increases the bioavailability of flavanones after dietary aronia-citrus juice intake in triathletes

10.1016/j.foodchem.2012.07.080 · 2012 · External reference

Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures

10.1016/j.bcp.2004.09.018 · 2005 · External reference

Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs

10.1016/j.exger.2004.01.007 · 2004 · External reference

Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine

10.1016/j.expneurol.2004.05.012 · 2004 · External reference

Post 6-OHDA lesion exposure to stress affects neurotrophic factor expression and aggravates motor impairment

10.1007/s11011-017-9988-1 · 2017 · External reference

Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells

10.1006/abbi.2001.2636 · 2002 · External reference

Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection

10.1016/j.neuroscience.2006.10.042 · 2007 · External reference

Levodopa: a new look at an old friend

10.1002/mds.27216 · 2018 · External reference

Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer’s disease

10.1016/j.neurobiolaging.2006.09.012 · 2008 · External reference

Potential therapeutic properties of green tea polyphenols in Parkinson’s disease

10.2165/00002512-200320100-00001 · 2003 · External reference

Neuroprotective and neurotrophic effects of Apigenin and Luteolin in MPTP induced parkinsonism in mice

10.1016/j.neuropharm.2014.07.012 · 2014 · External reference

Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays

2004 · External reference

Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats

10.1016/s0090-9556(25)07403-3 · 1993 · External reference

Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines

10.1523/jneurosci.6194-09.2010 · 2010 · External reference

Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine

10.1016/0306-4522(95)00066-r · 1995 · External reference

Effect of oral resveratrol on the BDNF gene expression in the hippocampus of the rat brain

10.1007/s11064-010-0396-8 · 2011 · External reference

Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats

10.1007/s00213-012-2719-8 · 2012 · External reference

Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency

10.1007/s12035-018-1256-9 · 2019 · External reference

Dissociation of Striatal Dopamine and Tyrosine Hydroxylase Expression from Aging-Related Motor Decline: Evidence from Calorie Restriction Intervention

10.1093/gerona/glx119 · 2017 · External reference

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat

10.1016/0306-4522(94)90605-x · 1994 · External reference

Effect of High-Intensity Treadmill Exercise on Motor Symptoms in Patients With De Novo Parkinson Disease: A Phase 2 Randomized Clinical Trial

10.1001/jamaneurol.2017.3517 · 2018 · External reference

Increased blood-brain barrier permeability following acute short-term swimming exercise in conscious normotensive young rats

10.1016/0168-0102(91)90058-7 · 1991 · External reference

Rehabilitation training and resveratrol improve the recovery of neurological and motor function in rats after cerebral ischemic injury through the sirt1 signaling pathway

10.1155/2016/1732163 · 2016 · External reference

The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing

10.1017/s0007114515003451 · 2015 · External reference

Effects of Concord grape juice on cognitive and motor deficits in aging

10.1016/j.nut.2005.07.016 · 2006 · External reference

Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats

10.1016/j.nut.2008.10.018 · 2009 · External reference

Effect of AdGDNF on dopaminergic neurotransmission in the striatum of 6-OHDA-treated rats

10.1016/j.expneurol.2005.01.010 · 2005 · External reference

Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain

10.1371/journal.pone.0024652 · 2011 · External reference

Continuous dopaminergic stimulation in early and advanced Parkinson's disease

10.1212/wnl.62.1_suppl_1.s56 · 2004 · External reference

Plant-derived flavanol (-)epicatechin mitigates anxiety in association with elevated hippocampal monoamine and BDNF levels, but does not influence pattern separation in mice

10.1038/tp.2014.135 · 2015 · External reference

Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system

10.1016/j.expneurol.2005.08.013 · 2005 · External reference

Exercise exerts neuroprotective effects on Parkinson’s disease model of rats

10.1016/j.brainres.2009.10.075 · 2010 · External reference

Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson’s disease

10.1016/j.neurobiolaging.2013.10.077 · 2014 · External reference

Automated imaging system for fast quantitation of neurons, cell morphology and neurite morphometry in vivo and in vitro

10.1016/j.nbd.2012.11.018 · 2013 · External reference

Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease

10.1016/s0306-4522(03)00096-4 · 2003 · External reference

Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine

10.1523/jneurosci.21-12-04427.2001 · 2001 · External reference

Vastly different exercise programs similarly improve parkinsonian symptoms: a randomized clinical trial

10.1159/000493127 · 2019 · External reference

Environmental risk factors of young onset Parkinson’s disease: a case-control study

10.1016/s0303-8467(02)00027-6 · 2002 · External reference

Long-Term Voluntary Physical Exercise Exerts Neuroprotective Effects and Motor Disturbance Alleviation in a Rat Model of Parkinson’s Disease

10.1155/2019/4829572 · 2019 · External reference

Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson’s disease: a double-blind, randomised controlled trial

10.1016/s1474-4422(19)30285-6 · 2019 · External reference

Beneficial effects of dietary EGCG and voluntary exercise on behavior in an Alzheimer’s disease mouse model

10.3233/jad-140981 · 2015 · External reference

Blood-brain barrier integrity may be threatened by exercise in a warm environment

2005 · External reference

Dose-dependent effects of walnuts on motor and cognitive function in aged rats

10.1017/s0007114508059369 · 2009 · External reference

Treadmill exercise suppresses nigrostriatal dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson’s rats

10.1016/j.neulet.2007.06.031 · 2007 · External reference

Histological, behavioural and neurochemical evaluation of medial forebrain bundle and striatal 6-OHDA lesions as rat models of Parkinson’s disease

10.1016/j.jneumeth.2004.10.004 · 2005 · External reference

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson’s disease

10.1080/10715760500233113 · 2005 · External reference

Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate-stage Amyloid Precursor Protein/Presenilin 1 Mice

10.4103/0973-1296.182174 · 2016 · External reference

Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical parkinsonism

10.1001/archneur.1984.04050190062015 · 1984 · External reference