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References from The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond. Local targets link to admitted publications; unresolved targets remain external evidence.
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite
10.1172/jci29867 · 2006 · External reference
Effects of ghrelin administration after total gastrectomy: a prospective, randomized, placebo-controlled phase II Study
10.1053/j.gastro.2009.12.058 · 2010 · External reference
NTS catecholamine neurons mediate hypoglycemic hunger via medial hypothalamic feeding pathways
2020 · External reference
The vagus nerve as a regulator of growth hormone secretion
10.1016/j.regpep.2010.10.008 · 2011 · External reference
Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach
10.1111/j.1365-2982.2007.00945.x · 2007 · External reference
Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat
10.1523/jneurosci.2606-06.2006 · 2006 · External reference
Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
2001 · External reference
Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin
10.1053/gast.2001.22158 · 2001 · External reference
Ghrelin is involved in the paracrine communication between neurons and glial cells
10.1111/nmo.12171 · 2013 · External reference
Functional and chemical anatomy of the afferent vagal system
10.1016/s1566-0702(00)00215-0 · 2000 · External reference
Characterization of vagal innervation to the rat celiac, suprarenal and mesenteric ganglia
10.1016/0165-1838(93)90046-w · 1993 · External reference
Diminished gastric prokinetic response to ghrelin in a rat model of spinal cord injury
10.1111/nmo.13258 · 2018 · External reference
Ghrelin gastrokinetic action in patients with neurogenic gastroparesis
10.1016/j.peptides.2005.12.008 · 2006 · External reference
Detection of G protein-coupled receptor expression in mouse vagal afferent neurons using multiplex in situ hybridization
2021 · External reference
Expression of the ghrelin receptor gene in neurons of the medulla oblongata of the rat
10.1002/cne.23309 · 2013 · External reference
A critical re-evaluation of the specificity of action of perivagal capsaicin
10.1113/jphysiol.2012.246827 · 2013 · External reference
Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance
10.1152/ajpgi.00543.2005 · 2006 · External reference
Circulating ghrelin acts on GABA neurons of the area postrema and mediates gastric emptying in male mice
10.1210/en.2016-1815 · 2017 · External reference
Analysis of brain nuclei accessible to ghrelin present in the cerebrospinal fluid
10.1016/j.neuroscience.2013.09.008 · 2013 · External reference
Ghrelin indirectly activates hypophysiotropic CRF neurons in rodents
10.1371/journal.pone.0031462 · 2012 · External reference
Divergent neuronal circuitries underlying acute orexigenic effects of peripheral or central ghrelin: critical role of brain accessibility
10.1111/jne.12168 · 2014 · External reference
Anatomy of the vagus nerve
2015 · External reference
A molecular census of arcuate hypothalamus and median eminence cell types
10.1038/nn.4495 · 2017 · External reference
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells
10.1523/jneurosci.6451-10.2011 · 2011 · External reference
Des-acyl ghrelin acts by CRF type 2 receptors to disrupt fasted stomach motility in conscious rats
10.1053/j.gastro.2005.04.015 · 2005 · External reference
Calcitonin receptor neurons in the mouse nucleus tractus solitarius control energy balance via the non-aversive suppression of feeding
2020 · External reference
Modulatory effect of methanandamide on gastric vagal afferent satiety signals depends on nutritional status
10.1113/jp279449 · 2020 · External reference
Vagus nerve stimulation activates nucleus of solitary tract neurons via supramedullary pathways
10.1113/jp282064 · 2021 · External reference
Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract
10.1007/s00429-018-1682-5 · 2018 · External reference
The intriguing ligand-dependent and ligand-independent actions of the growth hormone secretagogue receptor on reward-related behaviors
10.1016/j.neubiorev.2020.10.017 · 2021 · External reference
The ups and downs of growth hormone secretagogue receptor signaling
10.1111/febs.15718 · 2021 · External reference
Ghrelin infused into the portal vein inhibits glucose-stimulated insulin secretion in Wistar rats
10.1016/j.peptides.2008.02.022 · 2008 · External reference
Ghrelin inhibits visceral afferent activation of catecholamine neurons in the solitary tract nucleus
10.1523/jneurosci.3187-10.2011 · 2011 · External reference
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
10.2337/diabetes.50.8.1714 · 2001 · External reference
Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery
10.1056/nejmoa012908 · 2002 · External reference
Capsaicin-induced neuronal death and proliferation of the primary sensory neurons located in the nodose ganglia of adult rats
10.1016/j.neuroscience.2008.03.055 · 2008 · External reference
Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin
10.1016/s0306-4522(03)00327-0 · 2003 · External reference
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
10.1053/gast.2002.35954 · 2002 · External reference
Ghrelin acts in the central nervous system to stimulate gastric acid secretion
10.1006/bbrc.2000.4212 · 2001 · External reference
Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus
10.1016/j.cmet.2006.09.004 · 2006 · External reference
Peripheral interaction of ghrelin with cholecystokinin on feeding regulation
10.1210/en.2004-1240 · 2005 · External reference
Ghrelin signaling affects feeding behavior, metabolism, and memory through the vagus nerve
2020 · External reference
Cocaine- and amphetamine-regulated transcript: stimulation of expression in rat vagal afferent neurons by cholecystokinin and suppression by ghrelin
10.1523/jneurosci.5508-06.2007 · 2007 · External reference
EGR1 is a target for cooperative interactions between cholecystokinin and leptin, and inhibition by ghrelin, in vagal afferent neurons
10.1210/en.2010-0106 · 2010 · External reference
The migrating motor complex: control mechanisms and its role in health and disease
10.1038/nrgastro.2012.57 · 2012 · External reference
Enteroendocrine cell signalling via the vagus nerve
10.1016/j.coph.2013.09.007 · 2013 · External reference
Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice
10.1136/gut.2004.058578 · 2005 · External reference
Ghrelin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons
10.1016/j.regpep.2004.04.001 · 2004 · External reference
Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
10.1016/j.molmet.2018.03.016 · 2018 · External reference
Neuroendocrine response to exogenous ghrelin administration, combined with alcohol, in heavy-drinking individuals: findings from a randomized, double-blind, placebo-controlled human laboratory study
10.1093/ijnp/pyab004 · 2021 · External reference
Hyperphagic effects of brainstem ghrelin administration
10.2337/diabetes.52.9.2260 · 2003 · External reference
Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus
10.1016/j.brainres.2008.04.068 · 2008 · External reference
Evidence supporting a role for constitutive ghrelin receptor signaling in fasting-induced hyperphagia in male mice
10.1210/en.2017-03101 · 2018 · External reference
Ghrelin modulates electrical activity of area postrema neurons
10.1152/ajpregu.90555.2008 · 2009 · External reference
Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats
10.1113/jphysiol.2003.040600 · 2003 · External reference
Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats
10.1080/00365520410007908 · 2004 · External reference
Synergistic action of gastrin and ghrelin on gastric acid secretion in rats
10.1016/j.bbrc.2008.06.114 · 2008 · External reference
Neural proliferation and restoration of neurochemical phenotypes and compromised functions following capsaicin-induced neuronal damage in the nodose ganglion of the adult rat
10.3389/fnins.2011.00012 · 2011 · External reference
Vagal innervation patterns following Roux-en-Y gastric bypass in the mouse
10.1038/ijo.2013.48 · 2013 · External reference
LEAP2 is an endogenous antagonist of the ghrelin receptor
2018 · External reference
The orexigenic effect of peripheral ghrelin differs between rats of different age and with different baseline food intake, and it may in part be mediated by the area postrema
10.1016/j.physbeh.2005.10.015 · 2006 · External reference
Surviving starvation: essential role of the ghrelin-growth hormone axis
10.1101/sqb.2011.76.010447 · 2011 · External reference
KATP channels in the nodose ganglia mediate the orexigenic actions of ghrelin
10.1113/jp270788 · 2015 · External reference
Ghrelin as a target for gastrointestinal motility disorders
10.1016/j.peptides.2011.03.014 · 2011 · External reference
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
10.1016/s0169-328x(97)00071-5 · 1997 · External reference
Disrupting the ghrelin-growth hormone axis limits ghrelin’s orexigenic but not glucoregulatory actions
10.1016/j.molmet.2021.101258 · 2021 · External reference
A neural circuit for gut-induced reward
2018 · External reference
Centrally and peripherally administered ghrelin potently inhibits water intake in rats
10.1210/en.2006-0993 · 2007 · External reference
Neural injury, repair, and adaptation in the GI tract. II. The elusive action of capsaicin on the vagus nerve
1998 · External reference
A receptor in pituitary and hypothalamus that functions in growth hormone release
10.1126/science.273.5277.974 · 1996 · External reference
Hippocampus ghrelin receptor signaling promotes socially-mediated learned food preference
10.1016/j.neuropharm.2017.11.039 · 2018 · External reference
Ghrelin inhibits autonomic function in healthy controls, but has no effect on obese and vagotomized subjects
10.1111/j.1365-2265.2010.03865.x · 2010 · External reference
Ghrelin counteracts insulin-induced activation of vagal afferent neurons via growth hormone secretagogue receptor
10.1016/j.npep.2015.06.003 · 2015 · External reference
Diet-induced adaptation of vagal afferent function: adaptation of afferent function
10.1113/jphysiol.2011.222158 · 2012 · External reference
Regulation of gastrointestinal motility by motilin and ghrelin in vertebrates
10.3389/fendo.2019.00278 · 2019 · External reference
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
10.1038/45230 · 1999 · External reference
10.1111/bph.13439
10.1111/bph.13439 · 2016 · External reference
Specific postoperative syndromes after total and selective vagotomies in the rat
10.1016/s0195-6663(86)80038-1 · 1986 · External reference
An atlas of vagal sensory neurons and their molecular specialization
2019 · External reference
Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy
10.1210/jc.2004-2537 · 2005 · External reference
Ghrelin acts on the dorsal vagal complex to stimulate pancreatic protein secretion
10.1152/ajpgi.00493.2005 · 2006 · External reference
Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
10.1161/01.hyp.0000122803.91559.55 · 2004 · External reference
Ghrelin’s relationship to blood glucose
10.1210/en.2019-00074 · 2019 · External reference
Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse: characterization of Ghsr-egfp reporter mouse
10.1002/cne.23627 · 2014 · External reference
Genetic suppression of ghrelin receptors activates brown adipocyte function and decreases fat storage in rats
10.1016/j.regpep.2009.11.010 · 2010 · External reference
Ghrelin prevents incidence of malignant arrhythmia after acute myocardial infarction through vagal afferent nerves
10.1210/en.2012-1065 · 2012 · External reference
Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region
10.1016/j.jchemneu.2008.12.007 · 2009 · External reference
Ghrelin stimulates gastric acid secretion and motility in rats
10.1006/bbrc.2000.3568 · 2000 · External reference
Central ghrelin modulates sympathetic activity in conscious rabbits
10.1161/01.hyp.0000035395.51441.10 · 2002 · External reference
Ghrelin inhibits autonomic response to gastric distension in rats by acting on vagal pathway
10.1038/s41598-020-67053-y · 2020 · External reference
How reliable are G-protein-coupled receptor antibodies?
10.1007/s00210-009-0395-y · 2009 · External reference
Arterial baroreceptors sense blood pressure through decorated aortic claws
2019 · External reference
N-terminal liver-expressed antimicrobial peptide 2 (LEAP2) region exhibits inverse agonist activity toward the ghrelin receptor
10.1021/acs.jmedchem.8b01644 · 2019 · External reference
Ghrelin
10.1016/j.molmet.2015.03.005 · 2015 · External reference
Hemodynamic and hormonal effects of human ghrelin in healthy volunteers
10.1152/ajpregu.2001.280.5.r1483 · 2001 · External reference
A role for ghrelin in the central regulation of feeding
10.1038/35051587 · 2001 · External reference
Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation
10.1530/joe-15-0139 · 2015 · External reference
A method for selective section of vagal afferent or efferent axons in the rat
1994 · External reference
Analysis of peripheral ghrelin signaling via the vagus nerve in ghrelin receptor–restored GHSR-null mice
10.1016/j.neulet.2018.05.035 · 2018 · External reference
The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus
10.1016/j.euroneuro.2017.12.004 · 2018 · External reference
Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents
2007 · External reference
Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats
10.1152/ajpendo.90796.2008 · 2009 · External reference
Brain accessibility delineates the central effects of circulating ghrelin
10.1111/jne.12677 · 2019 · External reference
Long-term regeneration of abdominal vagus: efferents fail while afferents succeed
10.1002/cne.10470 · 2003 · External reference
Capsaicin receptor: TRPV1 a promiscuous TRP channel
10.1007/978-3-540-34891-7_9 · 2007 · External reference
Gastrointestinal tract innervation of the mouse: afferent regeneration and meal patterning after vagotomy
10.1152/ajpregu.00167.2005 · 2005 · External reference
Capsaicin-induced neuronal degeneration: silver impregnation of cell bodies, axons, and terminals in the central nervous system of the adult rat
10.1002/cne.902710109 · 1988 · External reference
The chemical neuroanatomy of vagus nerve stimulation
10.1016/j.jchemneu.2010.12.002 · 2011 · External reference
Plasticity of nodose ganglion neurons after capsaicin- and vagotomy-induced nerve damage in adult rats
10.1016/j.neuroscience.2010.02.049 · 2010 · External reference
Growth hormone secretagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion
10.1016/s0304-3940(03)00294-5 · 2003 · External reference
Comparison of the actions of acylated and desacylated ghrelin on acid secretion in the rat stomach
10.1007/s00535-010-0269-6 · 2010 · External reference
Ghrelin and motilin control systems in GI physiology and therapeutics
10.1007/164_2016_104 · 2017 · External reference
Regulation of GH secretagogue receptor gene expression in the rat nodose ganglion
10.1677/joe-06-0078 · 2007 · External reference
Central administration of ghrelin stimulates pancreatic exocrine secretion via the vagus in conscious rats
10.2170/jjphysiol.53.443 · 2003 · External reference
Subdiaphragmatic vagal deafferentation fails to block feeding-suppressive effects of LPS and IL-1 beta in rats
1997 · External reference
Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose
10.1371/journal.pone.0044089 · 2012 · External reference
Centrally administered ghrelin activates cardiac vagal nerve in anesthetized rabbits
10.1016/j.autneu.2011.04.001 · 2011 · External reference
Ghrelin directly targets the ventral tegmental area to increase food motivation
10.1016/j.neuroscience.2011.02.016 · 2011 · External reference
Ghrelin protects the heart against ischemia-induced arrhythmias by preserving connexin-43 protein
10.1007/s00380-013-0333-2 · 2013 · External reference
Neuroendocrine regulation of growth hormone secretion
10.1002/j.2040-4603.2016.tb00692.x · 2016 · External reference
Gut vagal sensory signaling regulates hippocampus function through multi-order pathways
10.1038/s41467-018-04639-1 · 2018 · External reference
Ghrelin increases vagally mediated gastric activity by central sites of action
10.1111/nmo.12261 · 2014 · External reference
Influence of ghrelin on interdigestive gastrointestinal motility in humans
10.1136/gut.2004.060426 · 2006 · External reference
Expression of c-Fos protein in the brain after intravenous injection of ghrelin in rats
10.1016/j.neulet.2007.02.089 · 2007 · External reference
Intravenous administration of ghrelin stimulates growth hormone secretion in vagotomized patients as well as normal subjects
10.1530/eje.0.1510447 · 2004 · External reference
Metabolic responses to exogenous ghrelin in obesity and early after Roux-en-Y gastric bypass in humans
10.1111/dom.12952 · 2017 · External reference
Effects of ghrelin on interdigestive contractions of the rat gastrointestinal tract
10.3748/wjg.14.6299 · 2008 · External reference
Highly selective brain-to-gut communication via genetically defined vagus neurons
2021 · External reference
A gut lipid messenger links excess dietary fat to dopamine deficiency
10.1126/science.1239275 · 2013 · External reference
Brainstem circuits regulating gastric function
10.1146/annurev.physiol.68.040504.094635 · 2006 · External reference
Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons
10.1016/j.molmet.2020.101070 · 2020 · External reference
Post-prandial decrease of circulating human ghrelin levels
2001 · External reference
Circulating ghrelin levels are decreased in human obesity
10.2337/diabetes.50.4.707 · 2001 · External reference
The brain-penetrating, orally bioavailable, ghrelin receptor agonist HM01 ameliorates motion-induced emesis in Suncus murinus (house musk shrew)
10.1111/bph.14924 · 2020 · External reference
Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons
10.3389/fnana.2015.00040 · 2015 · External reference
Dissecting the role of subtypes of gastrointestinal vagal afferents
10.3389/fphys.2020.00643 · 2020 · External reference
Ghrelin enhances appetite and increases food intake in humans
10.1210/jcem.86.12.8111 · 2001 · External reference
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
10.1210/endo.141.11.7873 · 2000 · External reference
Starvation after AgRP neuron ablation is independent of melanocortin signaling
10.1073/pnas.0712062105 · 2008 · External reference
Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples
10.1677/joe-10-0317 · 2011 · External reference
The growth hormone secretagogue receptor: its intracellular signaling and regulation
10.3390/ijms15034837 · 2014 · External reference
The Logic Of Carotid Body Connectivity To The Brain
10.1152/physiol.00057.2018 · 2019 · External reference
Inhibition of pancreatic protein secretion by ghrelin in the rat
10.1111/j.1469-7793.2001.0231k.x · 2001 · External reference
Ghrelin stimulates neurogenesis in the dorsal motor nucleus of the vagus: Stimulation of neurogenesis by ghrelin
10.1113/jphysiol.2004.064121 · 2004 · External reference
Functional interaction between Ghrelin and GLP-1 regulates feeding through the vagal afferent system
10.1038/s41598-020-75621-5 · 2020 · External reference
Modulation of food intake by mTOR signalling in the dorsal motor nucleus of the vagus in male rats: focus on ghrelin and nesfatin-1: mTOR in the dorsal motor nucleus of the vagus
10.1113/expphysiol.2013.074930 · 2013 · External reference
Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice
10.1073/pnas.1002271107 · 2010 · External reference
Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice
10.1111/j.1365-2982.2008.01179.x · 2009 · External reference
Expression of ghrelin receptor mRNA in the rat and the mouse brain
10.1002/cne.20823 · 2006 · External reference
Mice lacking ghrelin receptors resist the development of diet-induced obesity
10.1172/jci26002 · 2005 · External reference
