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References from The effects of Saccharomyces boulardii on TLR4/NF-κB neuroinflammatory pathway in the hippocampus of LPS-induced rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Kojic acid reverses LPS-induced neuroinflammation and cognitive impairment by regulating the TLR4/NF-κB signaling pathway
10.3389/fphar.2024.1443552 · 2024 · External reference
Preventive Effect of Saccharomyces boulardii on memory impairment induced by lipopolysaccharide in rats
10.1021/acschemneuro.2c00500 · 2022 · External reference
Saccharomyces boulardii attenuates lipopolysaccharide-induced anxiety-like behaviors in rats
10.1016/j.neulet.2022.136600 · 2022 · External reference
Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD-2/TLR4
10.1002/jlb.3mir1118-434r · 2019 · External reference
Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism
10.1016/j.pnpbp.2019.109661 · 2019 · External reference
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
10.1007/s00018-020-03656-y · 2021 · External reference
Molecular mechanisms of neurodegeneration in Alzheimer's disease
10.1093/hmg/ddq160 · 2010 · External reference
Lipopolysaccharide-induced animal models for neuroinflammation - An overview
10.1016/j.jneuroim.2023.578273 · 2024 · External reference
Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice
10.1016/j.pnpbp.2017.03.010 · 2017 · External reference
IUPHAR review: From gut to brain: The role of gut dysbiosis, bacterial amyloids, and metabolic disease in Alzheimer's disease
10.1016/j.phrs.2025.107693 · 2025 · External reference
The Gut Microbiota and Alzheimer's Disease
10.3233/jad-161141 · 2017 · External reference
Modulation of 5-fluorouracil activation of toll-like/MyD88/NF-κB/MAPK pathway by Saccharomyces boulardii CNCM I-745 probiotic
10.1016/j.cyto.2019.154791 · 2020 · External reference
Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal neurodevelopment processes
10.1007/s11011-022-00964-z · 2022 · External reference
Administration of Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI improves cognitive and memory function in the mouse model of Alzheimer’s disease
10.3389/fnagi.2021.709091 · 2021 · External reference
Roles of cyclic AMP response element binding activation in the ERK1/2 and p38 MAPK signalling pathway in central nervous system, cardiovascular system, osteoclast differentiation and mucin and cytokine production
10.3390/ijms20061346 · 2019 · External reference
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
10.1038/s41582-020-00435-y · 2021 · External reference
Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer’s disease
10.1007/s00406-007-0764-9 · 2008 · External reference
Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit
10.1093/cercor/bhaa008 · 2020 · External reference
Apelin-13 suppresses neuroinflammation against cognitive deficit in a streptozotocin-induced rat model of Alzheimer’s disease through activation of BDNF-TrkB signaling pathway
10.3389/fphar.2019.00395 · 2019 · External reference
Probiotics May Have Beneficial Effects in Parkinson's Disease: In vitro Evidence
10.3389/fimmu.2019.00969 · 2019 · External reference
Saccharomyces boulardii Ameliorates LPS-Induced Amyloidogenesis in Rats
10.1007/s12602-024-10445-7 · 2024 · External reference
Probiotic mixture of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 attenuates hippocampal apoptosis induced by lipopolysaccharide in rats
10.1007/s10123-018-00051-3 · 2019 · External reference
The effects of probiotic formulation pretreatment (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) on a lipopolysaccharide rat model
10.1080/07315724.2018.1487346 · 2019 · External reference
Microglia in neuroinflammation and neurodegeneration: from understanding to therapy
10.3389/fnins.2021.742065 · 2021 · External reference
Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer’s disease (AD): a systematic review and meta-analysis
10.3390/ijms20020257 · 2019 · External reference
The potential role of microbiota in age-related cognitive decline: a narrative review of the underlying molecular mechanisms
10.3390/ijms26041590 · 2025 · External reference
Hippocampal neuronal loss in the CA1 and CA3 areas of Alzheimer's disease patients
2012 · External reference
A window into the brain: tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders
10.1016/j.addr.2019.01.012 · 2019 · External reference
Saccharomyces boulardii ameliorates gut dysbiosis associated cognitive decline
2021 · External reference
Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial
10.1503/jpn.220117 · 2023 · External reference
β2-Integrin-induced p38 MAPK Activation Is a Key Mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes
10.1074/jbc.m803905200 · 2008 · External reference
Protective effects of Bacillus coagulans JA845 against D-galactose/AlCl3-induced cognitive decline, oxidative stress and neuroinflammation
10.4014/jmb.2111.11031 · 2022 · External reference
Gut-brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain functions
10.3390/ijms21207551 · 2020 · External reference
A probiotic modulates the microbiome and immunity in multiple sclerosis
10.1002/ana.25244 · 2018 · External reference
Saccharomyces boulardii improves the behaviour and emotions of spastic cerebral palsy rats through the gut-brain axis pathway
10.1186/s12868-021-00679-4 · 2021 · External reference
The effects of microglia-associated neuroinflammation on Alzheimer’s disease
2023 · External reference
Role of pro-inflammatory cytokines released from microglia in Alzheimer’s disease
2015 · External reference
NLRP3 inflammasome and inflammatory diseases
2020 · External reference
The gut microbiota modulates neuroinflammation in Alzheimer's disease: elucidating crucial factors and mechanistic underpinnings
10.1111/cns.70091 · 2024 · External reference
Probiotics modulate the microbiota–gut–brain axis and improve memory deficits in aged SAMP8 mice
10.1016/j.apsb.2019.07.001 · 2020 · External reference
Effect of probiotic fungi against cognitive impairment in mice via regulation of the fungal microbiota-gut-brain axis
10.1021/acs.jafc.2c03142 · 2022 · External reference
Lactobacillus gasseri NK109 and its supplement alleviate cognitive impairment in mice by modulating NF-κB activation, BDNF expression, and gut microbiota composition
10.3390/nu15030790 · 2023 · External reference
A probiotic modulates the microbiome and immunity in multiple sclerosis
10.1002/ana.25244 · ExternalCitation · doi-reference
Detecting lipopolysaccharide in the cytosol of mammalian cells: Lessons from MD-2/TLR4
10.1002/jlb.3mir1118-434r · ExternalCitation · doi-reference
TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
10.1007/s00018-020-03656-y · ExternalCitation · doi-reference
Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer’s disease
10.1007/s00406-007-0764-9 · ExternalCitation · doi-reference
Probiotic mixture of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 attenuates hippocampal apoptosis induced by lipopolysaccharide in rats
10.1007/s10123-018-00051-3 · ExternalCitation · doi-reference
Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal neurodevelopment processes
10.1007/s11011-022-00964-z · ExternalCitation · doi-reference
Saccharomyces boulardii Ameliorates LPS-Induced Amyloidogenesis in Rats
10.1007/s12602-024-10445-7 · ExternalCitation · doi-reference
A window into the brain: tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders
10.1016/j.addr.2019.01.012 · ExternalCitation · doi-reference
Probiotics modulate the microbiota–gut–brain axis and improve memory deficits in aged SAMP8 mice
10.1016/j.apsb.2019.07.001 · ExternalCitation · doi-reference
Modulation of 5-fluorouracil activation of toll-like/MyD88/NF-κB/MAPK pathway by Saccharomyces boulardii CNCM I-745 probiotic
10.1016/j.cyto.2019.154791 · ExternalCitation · doi-reference
Lipopolysaccharide-induced animal models for neuroinflammation - An overview
10.1016/j.jneuroim.2023.578273 · ExternalCitation · doi-reference
Saccharomyces boulardii attenuates lipopolysaccharide-induced anxiety-like behaviors in rats
10.1016/j.neulet.2022.136600 · ExternalCitation · doi-reference
IUPHAR review: From gut to brain: The role of gut dysbiosis, bacterial amyloids, and metabolic disease in Alzheimer's disease
10.1016/j.phrs.2025.107693 · ExternalCitation · doi-reference
Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice
10.1016/j.pnpbp.2017.03.010 · ExternalCitation · doi-reference
Interferon beta ameliorates cognitive dysfunction in a rat model of Alzheimer's disease: Modulation of hippocampal neurogenesis and apoptosis as underlying mechanism
10.1016/j.pnpbp.2019.109661 · ExternalCitation · doi-reference
Effect of probiotic fungi against cognitive impairment in mice via regulation of the fungal microbiota-gut-brain axis
10.1021/acs.jafc.2c03142 · ExternalCitation · doi-reference
Preventive Effect of Saccharomyces boulardii on memory impairment induced by lipopolysaccharide in rats
10.1021/acschemneuro.2c00500 · ExternalCitation · doi-reference
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
10.1038/s41582-020-00435-y · ExternalCitation · doi-reference
β2-Integrin-induced p38 MAPK Activation Is a Key Mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes
10.1074/jbc.m803905200 · ExternalCitation · doi-reference
The effects of probiotic formulation pretreatment (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) on a lipopolysaccharide rat model
10.1080/07315724.2018.1487346 · ExternalCitation · doi-reference
Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit
10.1093/cercor/bhaa008 · ExternalCitation · doi-reference
Molecular mechanisms of neurodegeneration in Alzheimer's disease
10.1093/hmg/ddq160 · ExternalCitation · doi-reference
The gut microbiota modulates neuroinflammation in Alzheimer's disease: elucidating crucial factors and mechanistic underpinnings
10.1111/cns.70091 · ExternalCitation · doi-reference
Saccharomyces boulardii improves the behaviour and emotions of spastic cerebral palsy rats through the gut-brain axis pathway
10.1186/s12868-021-00679-4 · ExternalCitation · doi-reference
Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial
10.1503/jpn.220117 · ExternalCitation · doi-reference
The Gut Microbiota and Alzheimer's Disease
10.3233/jad-161141 · ExternalCitation · doi-reference
Probiotics May Have Beneficial Effects in Parkinson's Disease: In vitro Evidence
10.3389/fimmu.2019.00969 · ExternalCitation · doi-reference
Administration of Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI improves cognitive and memory function in the mouse model of Alzheimer’s disease
10.3389/fnagi.2021.709091 · ExternalCitation · doi-reference
Microglia in neuroinflammation and neurodegeneration: from understanding to therapy
10.3389/fnins.2021.742065 · ExternalCitation · doi-reference
Apelin-13 suppresses neuroinflammation against cognitive deficit in a streptozotocin-induced rat model of Alzheimer’s disease through activation of BDNF-TrkB signaling pathway
10.3389/fphar.2019.00395 · ExternalCitation · doi-reference
Kojic acid reverses LPS-induced neuroinflammation and cognitive impairment by regulating the TLR4/NF-κB signaling pathway
10.3389/fphar.2024.1443552 · ExternalCitation · doi-reference
Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer’s disease (AD): a systematic review and meta-analysis
10.3390/ijms20020257 · ExternalCitation · doi-reference
Roles of cyclic AMP response element binding activation in the ERK1/2 and p38 MAPK signalling pathway in central nervous system, cardiovascular system, osteoclast differentiation and mucin and cytokine production
10.3390/ijms20061346 · ExternalCitation · doi-reference
Gut-brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain functions
10.3390/ijms21207551 · ExternalCitation · doi-reference
The potential role of microbiota in age-related cognitive decline: a narrative review of the underlying molecular mechanisms
10.3390/ijms26041590 · ExternalCitation · doi-reference
Lactobacillus gasseri NK109 and its supplement alleviate cognitive impairment in mice by modulating NF-κB activation, BDNF expression, and gut microbiota composition
10.3390/nu15030790 · ExternalCitation · doi-reference
Protective effects of Bacillus coagulans JA845 against D-galactose/AlCl3-induced cognitive decline, oxidative stress and neuroinflammation
10.4014/jmb.2111.11031 · ExternalCitation · doi-reference
