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References from miR-125a-5p inhibits NF-κB by negatively regulating TRAF2 to alleviate inflammatory injury in ischemic stroke rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function
10.1016/j.bcmd.2021.102624 · 2021 · External reference
Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function
10.1016/j.bcmd.2021.102624 · 2021 · External reference
KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis
10.1093/nar/gkab447 · 2021 · External reference
KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis
10.1093/nar/gkab447 · 2021 · External reference
Inhibition of miR-19a-3p decreases cerebral ischemia/reperfusion injury by targeting IGFBP3 in vivo and in vitro
10.1186/s40659-020-00280-9 · 2020 · External reference
Inhibition of miR-19a-3p decreases cerebral ischemia/reperfusion injury by targeting IGFBP3 in vivo and in vitro
10.1186/s40659-020-00280-9 · 2020 · External reference
Thromboinflammation in Brain Ischemia: Recent Updates and Future Perspectives
10.1161/strokeaha.122.038733 · 2022 · External reference
Thromboinflammation in Brain Ischemia: Recent Updates and Future Perspectives
10.1161/strokeaha.122.038733 · 2022 · External reference
Amphibian-derived peptides as novel therapeutics for skin wound healing: Mechanisms, applications, and challenges
10.24272/j.issn.2095-8137.2026.076 · 2026 · External reference
Amphibian-derived peptides as novel therapeutics for skin wound healing: Mechanisms, applications, and challenges
10.24272/j.issn.2095-8137.2026.076 · 2026 · External reference
Astrocytes-derived exosomes pre-treated by berberine inhibit neuroinflammation after stroke via miR-182-5p/Rac1 pathway
10.1016/j.intimp.2023.110047 · 2023 · External reference
Astrocytes-derived exosomes pre-treated by berberine inhibit neuroinflammation after stroke via miR-182-5p/Rac1 pathway
10.1016/j.intimp.2023.110047 · 2023 · External reference
The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond
10.1152/physrev.00045.2017 · 2019 · External reference
The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond
10.1152/physrev.00045.2017 · 2019 · External reference
Anti-inflammatory treatments for stroke: from bench to bedside
10.1177/1756286418789854 · 2018 · External reference
Anti-inflammatory treatments for stroke: from bench to bedside
10.1177/1756286418789854 · 2018 · External reference
Neuroprotective approach in acute ischemic stroke: a systematic review of clinical and experimental studies
10.4103/bc.bc_52_22 · 2022 · External reference
Neuroprotective approach in acute ischemic stroke: a systematic review of clinical and experimental studies
10.4103/bc.bc_52_22 · 2022 · External reference
The ischemic penumbra: From concept to reality
10.1177/1747493020975229 · 2021 · External reference
The ischemic penumbra: From concept to reality
10.1177/1747493020975229 · 2021 · External reference
Multifunctional pH-responsive HA-c-FZ1 hydrogel presents a promising therapeutic strategy for diabetic skin wounds
10.1093/burnst/tkag046 · 2026 · External reference
Multifunctional pH-responsive HA-c-FZ1 hydrogel presents a promising therapeutic strategy for diabetic skin wounds
10.1093/burnst/tkag046 · 2026 · External reference
A frog bioactive peptide suppresses inflammation by modulating autophagy for skin wound regeneration
10.1038/s42003-026-10766-z · 2026 · External reference
A frog bioactive peptide suppresses inflammation by modulating autophagy for skin wound regeneration
10.1038/s42003-026-10766-z · 2026 · External reference
Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation
10.1161/01.str.26.4.627 · 1995 · External reference
Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation
10.1161/01.str.26.4.627 · 1995 · External reference
The combination of RL-QN15 and OH-CATH30 promotes the repair of acne via the TLR2/NF-κB pathway
10.1016/j.ejphar.2024.177233 · 2025 · External reference
The combination of RL-QN15 and OH-CATH30 promotes the repair of acne via the TLR2/NF-κB pathway
10.1016/j.ejphar.2024.177233 · 2025 · External reference
Emerging ferroptosis inhibitors as a novel therapeutic strategy for the treatment of neonatal hypoxic-ischemic encephalopathy
10.1016/j.ejmech.2024.116453 · 2024 · External reference
Emerging ferroptosis inhibitors as a novel therapeutic strategy for the treatment of neonatal hypoxic-ischemic encephalopathy
10.1016/j.ejmech.2024.116453 · 2024 · External reference
Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke
10.1161/strokeaha.120.032810 · 2021 · External reference
Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke
10.1161/strokeaha.120.032810 · 2021 · External reference
Molecular pathophysiological mechanisms of ischemia/reperfusion injuries after recanalization therapy for acute ischemic stroke
10.31083/j.jin2003078 · 2021 · External reference
Molecular pathophysiological mechanisms of ischemia/reperfusion injuries after recanalization therapy for acute ischemic stroke
10.31083/j.jin2003078 · 2021 · External reference
Neuroinflammation in Cerebral Ischemia and Ischemia/Reperfusion Injuries: From Pathophysiology to Therapeutic Strategies
10.3390/ijms23010014 · 2021 · External reference
Neuroinflammation in Cerebral Ischemia and Ischemia/Reperfusion Injuries: From Pathophysiology to Therapeutic Strategies
10.3390/ijms23010014 · 2021 · External reference
KEGG: new perspectives on genomes, pathways, diseases and drugs
10.1093/nar/gkw1092 · 2017 · External reference
KEGG: new perspectives on genomes, pathways, diseases and drugs
10.1093/nar/gkw1092 · 2017 · External reference
Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier
10.1016/j.ecoenv.2025.118465 · 2025 · External reference
Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier
10.1016/j.ecoenv.2025.118465 · 2025 · External reference
TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis
10.1038/cddis.2014.404 · 2014 · External reference
TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis
10.1038/cddis.2014.404 · 2014 · External reference
miR-125a-5p in astrocytes attenuates peripheral neuropathy in type 2 diabetic mice through targeting TRAF6
10.1016/j.endinu.2021.01.007 · 2022 · External reference
miR-125a-5p in astrocytes attenuates peripheral neuropathy in type 2 diabetic mice through targeting TRAF6
10.1016/j.endinu.2021.01.007 · 2022 · External reference
Epigenetic regulation of transcription factors involved in NLRP3 inflammasome and NF-κB signaling pathways
10.3389/fimmu.2025.1529756 · 2025 · External reference
Epigenetic regulation of transcription factors involved in NLRP3 inflammasome and NF-κB signaling pathways
10.3389/fimmu.2025.1529756 · 2025 · External reference
The open field test for measuring locomotor activity and anxiety-like behavior
10.1007/978-1-4939-8994-2_9 · 2019 · External reference
The open field test for measuring locomotor activity and anxiety-like behavior
10.1007/978-1-4939-8994-2_9 · 2019 · External reference
Filling the gaps on stroke research: Focus on inflammation and immunity
10.1016/j.bbi.2020.09.025 · 2021 · External reference
Filling the gaps on stroke research: Focus on inflammation and immunity
10.1016/j.bbi.2020.09.025 · 2021 · External reference
Gomisin N attenuated cerebral ischemia-reperfusion injury through inhibition of autophagy by activating the PI3K/AKT/mTOR pathway
10.1016/j.phymed.2023.154644 · 2023 · External reference
Gomisin N attenuated cerebral ischemia-reperfusion injury through inhibition of autophagy by activating the PI3K/AKT/mTOR pathway
10.1016/j.phymed.2023.154644 · 2023 · External reference
Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
10.1161/01.str.24.1.117 · 1993 · External reference
Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
10.1161/01.str.24.1.117 · 1993 · External reference
Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation
10.3389/fimmu.2019.02408 · 2019 · External reference
Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation
10.3389/fimmu.2019.02408 · 2019 · External reference
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression
10.2174/1570159x21666230502111013 · 2023 · External reference
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression
10.2174/1570159x21666230502111013 · 2023 · External reference
First identification of an amphibian-derived peptide with anti-vascular aging activity
2026 · External reference
First identification of an amphibian-derived peptide with anti-vascular aging activity
2026 · External reference
Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury
10.1186/s12974-020-01761-0 · 2020 · External reference
Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury
10.1186/s12974-020-01761-0 · 2020 · External reference
Dynamic regulation and targeted interventions of macrophages in ischemia-reperfusion injury
10.1016/j.jare.2025.05.006 · 2026 · External reference
Dynamic regulation and targeted interventions of macrophages in ischemia-reperfusion injury
10.1016/j.jare.2025.05.006 · 2026 · External reference
Propofol Attenuates Inflammatory Damage via Inhibiting NLRP1-Casp1-Casp6 Signaling in Ischemic Brain Injury
10.1248/bpb.b20-00050 · 2020 · External reference
Propofol Attenuates Inflammatory Damage via Inhibiting NLRP1-Casp1-Casp6 Signaling in Ischemic Brain Injury
10.1248/bpb.b20-00050 · 2020 · External reference
New epigenetic players in stroke pathogenesis: From non-coding RNAs to exosomal non-coding RNAs
10.1016/j.biopha.2021.111753 · 2021 · External reference
New epigenetic players in stroke pathogenesis: From non-coding RNAs to exosomal non-coding RNAs
10.1016/j.biopha.2021.111753 · 2021 · External reference
The NF-κB signaling system in the immunopathogenesis of inflammatory bowel disease
10.1126/scisignal.adh1641 · 2024 · External reference
The NF-κB signaling system in the immunopathogenesis of inflammatory bowel disease
10.1126/scisignal.adh1641 · 2024 · External reference
Targeting vascular inflammation through emerging methods and drug carriers
10.1016/j.addr.2022.114180 · 2022 · External reference
Targeting vascular inflammation through emerging methods and drug carriers
10.1016/j.addr.2022.114180 · 2022 · External reference
MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
10.1016/j.immuni.2010.09.009 · 2010 · External reference
MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
10.1016/j.immuni.2010.09.009 · 2010 · External reference
Amphibian-Derived Peptide OA-AL14 Alleviates UVB-Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway
10.1111/1749-4877.70134 · 2026 · External reference
Amphibian-Derived Peptide OA-AL14 Alleviates UVB-Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway
10.1111/1749-4877.70134 · 2026 · External reference
TRAF2 is a biologically important necroptosis suppressor
10.1038/s41418-025-01601-9 · 2026 · External reference
TRAF2 is a biologically important necroptosis suppressor
10.1038/s41418-025-01601-9 · 2026 · External reference
The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery
10.3390/biom13030571 · 2023 · External reference
The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery
10.3390/biom13030571 · 2023 · External reference
Electroacupuncture Alleviates Ischemic Brain Injury by Inhibiting the miR-223/NLRP3 Pathway
10.12659/msm.917213 · 2019 · External reference
Electroacupuncture Alleviates Ischemic Brain Injury by Inhibiting the miR-223/NLRP3 Pathway
10.12659/msm.917213 · 2019 · External reference
Downregulation of miR-125a-5p Leads to STAT3 Increased Expression in Breast Cancer Patients
10.2174/2211536611666220907125812 · 2022 · External reference
Downregulation of miR-125a-5p Leads to STAT3 Increased Expression in Breast Cancer Patients
10.2174/2211536611666220907125812 · 2022 · External reference
MiR-125a-5p silencing inhibits cerebral ischemia-induced injury through targeting IGFBP3
10.5114/fn.2021.107109 · 2021 · External reference
MiR-125a-5p silencing inhibits cerebral ischemia-induced injury through targeting IGFBP3
10.5114/fn.2021.107109 · 2021 · External reference
Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion
10.1016/j.jneuroim.2017.01.015 · 2017 · External reference
Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion
10.1016/j.jneuroim.2017.01.015 · 2017 · External reference
The non-canonical NF-κB pathway in immunity and inflammation
10.1038/nri.2017.52 · 2017 · External reference
The non-canonical NF-κB pathway in immunity and inflammation
10.1038/nri.2017.52 · 2017 · External reference
NF-κB, inflammation, immunity and cancer: coming of age
10.1038/nri.2017.142 · 2018 · External reference
NF-κB, inflammation, immunity and cancer: coming of age
10.1038/nri.2017.142 · 2018 · External reference
Emerging targets for modulation of immune response and inflammation in stroke
10.1007/s11064-023-03875-2 · 2023 · External reference
Emerging targets for modulation of immune response and inflammation in stroke
10.1007/s11064-023-03875-2 · 2023 · External reference
Estimated burden of stroke in China in 2020
10.1001/jamanetworkopen.2023.1455 · 2023 · External reference
Estimated burden of stroke in China in 2020
10.1001/jamanetworkopen.2023.1455 · 2023 · External reference
MiRNA-34c-5p protects against cerebral ischemia/reperfusion injury: involvement of anti-apoptotic and anti-inflammatory activities
10.1007/s11011-021-00724-5 · 2021 · External reference
MiRNA-34c-5p protects against cerebral ischemia/reperfusion injury: involvement of anti-apoptotic and anti-inflammatory activities
10.1007/s11011-021-00724-5 · 2021 · External reference
Food-derived peptide RDP3 mitigates pyroptosis to enhance oral mucosal repair via the IL-2Rβ/PI3K axis
10.1142/14709 · 2026 · External reference
Food-derived peptide RDP3 mitigates pyroptosis to enhance oral mucosal repair via the IL-2Rβ/PI3K axis
10.1142/14709 · 2026 · External reference
Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke
10.3390/antiox11122377 · 2022 · External reference
Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke
10.3390/antiox11122377 · 2022 · External reference
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
10.1038/s41419-021-03725-5 · 2021 · External reference
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
10.1038/s41419-021-03725-5 · 2021 · External reference
MicroRNA Let-7i Is a Promising Serum Biomarker for Post-stroke Cognitive Impairment and Alleviated OGD-Induced Cell Damage in vitro by Regulating Bcl-2
10.3389/fnins.2020.00215 · 2020 · External reference
MicroRNA Let-7i Is a Promising Serum Biomarker for Post-stroke Cognitive Impairment and Alleviated OGD-Induced Cell Damage in vitro by Regulating Bcl-2
10.3389/fnins.2020.00215 · 2020 · External reference
LncRNA Gm4419 contributes to OGD/R injury of cerebral microglial cells via IκB phosphorylation and NF-κB activation
10.1016/j.bbrc.2017.05.005 · 2017 · External reference
LncRNA Gm4419 contributes to OGD/R injury of cerebral microglial cells via IκB phosphorylation and NF-κB activation
10.1016/j.bbrc.2017.05.005 · 2017 · External reference
Integrated Analysis of Competitive Endogenous RNA Networks in Acute Ischemic Stroke
2022 · External reference
Integrated Analysis of Competitive Endogenous RNA Networks in Acute Ischemic Stroke
2022 · External reference
miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma
10.18632/aging.102276 · 2019 · External reference
miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma
10.18632/aging.102276 · 2019 · External reference
Reduced expression of MiR-125a-5p aggravates LPS-induced experimental acute kidney injury pathology by targeting TRAF6
10.1016/j.lfs.2021.119657 · 2022 · External reference
Reduced expression of MiR-125a-5p aggravates LPS-induced experimental acute kidney injury pathology by targeting TRAF6
10.1016/j.lfs.2021.119657 · 2022 · External reference
Peptide OM-LV20 protects astrocytes against oxidative stress via the 'PAC1R/JNK/TPH1' axis
10.1016/j.jbc.2022.102429 · 2022 · External reference
Peptide OM-LV20 protects astrocytes against oxidative stress via the 'PAC1R/JNK/TPH1' axis
10.1016/j.jbc.2022.102429 · 2022 · External reference
Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
10.1038/s41392-020-00312-6 · 2020 · External reference
Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
10.1038/s41392-020-00312-6 · 2020 · External reference
Propofol‑induced miR‑125a‑5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B
10.3892/mmr.2020.11223 · 2020 · External reference
Propofol‑induced miR‑125a‑5p inhibits the proliferation and metastasis of ovarian cancer by suppressing LIN28B
10.3892/mmr.2020.11223 · 2020 · External reference
Up-regulation of exosomal miR-125a in pneumoconiosis inhibits lung cancer development by suppressing expressions of EZH2 and hnRNPK.
10.1039/c8ra03081b · 2018 · External reference
Up-regulation of exosomal miR-125a in pneumoconiosis inhibits lung cancer development by suppressing expressions of EZH2 and hnRNPK.
10.1039/c8ra03081b · 2018 · External reference
The cystathionine β-synthase/hydrogen sulfide pathway contributes to microglia-mediated neuroinflammation following cerebral ischemia
10.1016/j.bbi.2017.07.156 · 2017 · External reference
The cystathionine β-synthase/hydrogen sulfide pathway contributes to microglia-mediated neuroinflammation following cerebral ischemia
10.1016/j.bbi.2017.07.156 · 2017 · External reference
Cell Death Mechanisms in Cerebral Ischemia-Reperfusion Injury
10.1007/s11064-022-03697-8 · 2022 · External reference
Cell Death Mechanisms in Cerebral Ischemia-Reperfusion Injury
10.1007/s11064-022-03697-8 · 2022 · External reference
Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment (Review)
10.3892/ijmm.2021.5070 · 2022 · External reference
Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment (Review)
10.3892/ijmm.2021.5070 · 2022 · External reference
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway
10.1186/s12974-021-02172-5 · 2021 · External reference
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway
10.1186/s12974-021-02172-5 · 2021 · External reference
MiR-155: An Important Regulator of Neuroinflammation
10.3390/ijms23010090 · 2021 · External reference
MiR-155: An Important Regulator of Neuroinflammation
10.3390/ijms23010090 · 2021 · External reference