Research graph
References from Moringa oleifera Leaf-Derived Exosome-Like Nanoparticles Target Macrophage Senescence to Drive M2 Polarisation and Attenuate Alveolar Bone Loss. Local targets link to admitted publications; unresolved targets remain external evidence.
New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration
10.1186/s12951-023-02261-y · 2024 · External reference
Immunotherapies based on macrophage reprogramming in periodontitis and apical periodontitis
10.1007/s00784-026-06918-4 · 2026 · External reference
Trem1 induces periodontal inflammation via regulating M1 polarization
10.1177/00220345211044681 · 2022 · External reference
A new direction in periodontitis treatment: biomaterial-mediated macrophage immunotherapy
10.1186/s12951-024-02592-4 · 2024 · External reference
Effect and mechanism of apoptotic bodies from inflammatory periodontal ligament stem cells on macrophage M1 polarisation
10.1016/j.identj.2025.103981 · 2026 · External reference
The immune regulatory mechanism of adrenomedullin on promoting the proliferation and differentiation of dental pulp stem cells
10.1016/j.identj.2024.04.022 · 2024 · External reference
Plant exosome nanovesicles (PENs): green delivery platforms
10.1039/d3mh01030a · 2023 · External reference
The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment
10.3389/fimmu.2022.896745 · 2022 · External reference
Therapeutic potential of ginger exosome-like nanoparticles for alleviating periodontitis-induced tissue damage
10.2147/ijn.s483091 · 2024 · External reference
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
10.1186/s40425-019-0817-4 · 2019 · External reference
Rgl-exomiR-7972, a novel plant exosomal microRNA derived from fresh Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung injury and gut dysbiosis
10.1016/j.biopha.2023.115007 · 2023 · External reference
Metabolic profile, antioxidant, antimicrobial, contractile, and anti-inflammatory potential of Moringa oleifera leaves (India)
2025 · External reference
Moringa oleifera: a review of the pharmacology, chemical constituents, and application for dental health
10.3390/ph17010142 · 2024 · External reference
Effect of Moringa oleifera on inflammatory diseases: an umbrella review of 26 systematic reviews
10.3389/fphar.2025.1572337 · 2025 · External reference
Moringa oleifera Lam. leaf extract safely inhibits periodontitis by regulating the expression of p38alpha/MAPK14-OPG/RANKL
10.1016/j.archoralbio.2021.105280 · 2021 · External reference
Plant exosome-like nanovesicles derived from sesame leaves as carriers for luteolin delivery: molecular docking, stability and bioactivity
10.1016/j.foodchem.2023.137963 · 2024 · External reference
Mesoporous Iron(III)-doped hydroxyapatite nanopowders obtained via iron oxalate
2021 · External reference
Bone marrow mesenchymal stem cells have tissue-specific characteristic in promoting the potential of periodontal ligament stem cells for periodontal regeneration
2026 · External reference
Contribution of macrophage polarization in bone metabolism: a literature review
10.1016/j.cyto.2024.156768 · 2024 · External reference
Engineering strategies of plant-derived exosome-like nanovesicles: current knowledge and future perspectives
10.2147/ijn.s496664 · 2024 · External reference
Structural basis for the ligand recognition and signaling of free fatty acid receptors
10.1126/sciadv.adj2384 · 2024 · External reference
An updated review of pro- and anti-inflammatory properties of plasma lysophosphatidylcholines in the vascular system
10.3390/ijms21124501 · 2020 · External reference
Pyroptotic macrophages induce disruption of glutamate metabolism in periodontal ligament stem cells contributing to their compromised osteogenic potential
10.1111/cpr.13663 · 2024 · External reference
CDllb+ targeted depletion of macrophages negatively affects bone fracture healing
10.1016/j.bone.2020.115479 · 2020 · External reference
Inducing in situ M2 macrophage polarization to promote the repair of bone defects via scaffold-mediated sustained delivery of luteolin
10.1016/j.jconrel.2023.11.015 · 2024 · External reference
X-box binding protein 1 regulates osteogenesis of periodontal ligament cells during aging by modulating P53 signaling pathway
10.1155/sci/2846096 · 2026 · External reference
The role of macrophage death in periodontitis: a review
10.1007/s10753-024-02015-4 · 2024 · External reference
Cellular senescence: a new perspective on the suppression of periodontitis (Review)
10.3892/mmr.2024.13362 · 2024 · External reference
A new model and precious tool to study molecular mechanisms of macrophage aging
10.18632/aging.206124 · 2024 · External reference
Comparative testing of two ligature-induced periodontitis models in rats: a clinical, histological and biochemical study
2022 · External reference
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery
10.7150/thno.97096 · 2024 · External reference
Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment
10.1016/j.phrs.2023.106733 · 2023 · External reference
Plant-derived exosomal nanoparticles: potential therapeutic for inflammatory bowel disease
10.1039/d3na00093a · 2023 · External reference
Paris polyphylla var. yunnanensis leaf-derived extracellular vesicle-like particles enhance periodontal regeneration
10.34133/bmr.0291 · 2025 · External reference
Immunotherapies based on macrophage reprogramming in periodontitis and apical periodontitis
10.1007/s00784-026-06918-4 · ExternalCitation · doi-reference
The role of macrophage death in periodontitis: a review
10.1007/s10753-024-02015-4 · ExternalCitation · doi-reference
Moringa oleifera Lam. leaf extract safely inhibits periodontitis by regulating the expression of p38alpha/MAPK14-OPG/RANKL
10.1016/j.archoralbio.2021.105280 · ExternalCitation · doi-reference
Rgl-exomiR-7972, a novel plant exosomal microRNA derived from fresh Rehmanniae Radix, ameliorated lipopolysaccharide-induced acute lung injury and gut dysbiosis
10.1016/j.biopha.2023.115007 · ExternalCitation · doi-reference
CDllb+ targeted depletion of macrophages negatively affects bone fracture healing
10.1016/j.bone.2020.115479 · ExternalCitation · doi-reference
Contribution of macrophage polarization in bone metabolism: a literature review
10.1016/j.cyto.2024.156768 · ExternalCitation · doi-reference
Plant exosome-like nanovesicles derived from sesame leaves as carriers for luteolin delivery: molecular docking, stability and bioactivity
10.1016/j.foodchem.2023.137963 · ExternalCitation · doi-reference
The immune regulatory mechanism of adrenomedullin on promoting the proliferation and differentiation of dental pulp stem cells
10.1016/j.identj.2024.04.022 · ExternalCitation · doi-reference
Effect and mechanism of apoptotic bodies from inflammatory periodontal ligament stem cells on macrophage M1 polarisation
10.1016/j.identj.2025.103981 · ExternalCitation · doi-reference
Inducing in situ M2 macrophage polarization to promote the repair of bone defects via scaffold-mediated sustained delivery of luteolin
10.1016/j.jconrel.2023.11.015 · ExternalCitation · doi-reference
Current understanding of plant-derived exosome-like nanoparticles in regulating the inflammatory response and immune system microenvironment
10.1016/j.phrs.2023.106733 · ExternalCitation · doi-reference
Plant exosome nanovesicles (PENs): green delivery platforms
10.1039/d3mh01030a · ExternalCitation · doi-reference
Plant-derived exosomal nanoparticles: potential therapeutic for inflammatory bowel disease
10.1039/d3na00093a · ExternalCitation · doi-reference
Pyroptotic macrophages induce disruption of glutamate metabolism in periodontal ligament stem cells contributing to their compromised osteogenic potential
10.1111/cpr.13663 · ExternalCitation · doi-reference
Structural basis for the ligand recognition and signaling of free fatty acid receptors
10.1126/sciadv.adj2384 · ExternalCitation · doi-reference
X-box binding protein 1 regulates osteogenesis of periodontal ligament cells during aging by modulating P53 signaling pathway
10.1155/sci/2846096 · ExternalCitation · doi-reference
Trem1 induces periodontal inflammation via regulating M1 polarization
10.1177/00220345211044681 · ExternalCitation · doi-reference
New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration
10.1186/s12951-023-02261-y · ExternalCitation · doi-reference
A new direction in periodontitis treatment: biomaterial-mediated macrophage immunotherapy
10.1186/s12951-024-02592-4 · ExternalCitation · doi-reference
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth
10.1186/s40425-019-0817-4 · ExternalCitation · doi-reference
A new model and precious tool to study molecular mechanisms of macrophage aging
10.18632/aging.206124 · ExternalCitation · doi-reference
Therapeutic potential of ginger exosome-like nanoparticles for alleviating periodontitis-induced tissue damage
10.2147/ijn.s483091 · ExternalCitation · doi-reference
Engineering strategies of plant-derived exosome-like nanovesicles: current knowledge and future perspectives
10.2147/ijn.s496664 · ExternalCitation · doi-reference
The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment
10.3389/fimmu.2022.896745 · ExternalCitation · doi-reference
Effect of Moringa oleifera on inflammatory diseases: an umbrella review of 26 systematic reviews
10.3389/fphar.2025.1572337 · ExternalCitation · doi-reference
An updated review of pro- and anti-inflammatory properties of plasma lysophosphatidylcholines in the vascular system
10.3390/ijms21124501 · ExternalCitation · doi-reference
Moringa oleifera: a review of the pharmacology, chemical constituents, and application for dental health
10.3390/ph17010142 · ExternalCitation · doi-reference
Paris polyphylla var. yunnanensis leaf-derived extracellular vesicle-like particles enhance periodontal regeneration
10.34133/bmr.0291 · ExternalCitation · doi-reference
Cellular senescence: a new perspective on the suppression of periodontitis (Review)
10.3892/mmr.2024.13362 · ExternalCitation · doi-reference
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery
10.7150/thno.97096 · ExternalCitation · doi-reference
