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References from Combined antibacterial activity of imipenem-funobactam with different antibiotics against carbapenem-resistant gram-negative bacteria in China. Local targets link to admitted publications; unresolved targets remain external evidence.
Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections with Polymyxins: A Review
10.2147/idr.s559556 · 2025 · External reference
Mechanisms, therapeutic strategies, and emerging therapeutic alternatives for carbapenem resistance in Gram-negative bacteria
10.1007/s00203-025-04252-z · 2025 · External reference
Carbapenem-resistant Gram-negative bacteria (CR-GNB) in ICUs: resistance genes, therapeutics, and prevention - a comprehensive review
2024 · External reference
β-Lactams and β-Lactamase Inhibitors: An Overview
10.1101/cshperspect.a025247 · 2016 · External reference
A systematic review and individual bacterial species level meta-analysis of in vitro studies on the efficacy of ceftazidime/avibactam combined with other antimicrobials against carbapenem-resistant Gram-negative bacteria
10.1093/jac/dkae451 · 2025 · External reference
Ceftazidime-avibactam combination therapy versus monotherapy for treating carbapenem-resistant gram-negative infection: a systemic review and meta-analysis
10.1007/s15010-024-02277-y · 2024 · External reference
In Vitro Susceptibility to Ceftazidime-Avibactam of Carbapenem-Nonsusceptible Enterobacteriaceae Isolates Collected during the INFORM Global Surveillance Study (2012 to 2014)
10.1128/aac.03042-15 · 2016 · External reference
Ceftazidime-avibactam activity tested against Enterobacteriaceae isolates from U.S. hospitals (2011 to 2013) and characterization of beta-lactamase-producing strains
10.1128/aac.00163-15 · 2015 · External reference
Imipenem/funobactam (formerly XNW4107) in vivo pharmacodynamics against serine carbapenemase-producing Gram-negative bacteria: a novel modelling approach for time-dependent killing
10.1093/jac/dkad242 · 2023 · External reference
In vitro and in vivo activities of a novel beta-lactamase inhibitor combination imipenem/XNW4107 against recent clinical Gram-negative bacilli from China
10.1016/j.jgar.2022.07.006 · 2022 · External reference
beta-Lactam/beta-Lactamase Inhibitor Combination Antibiotics Under Development
10.3390/pathogens14020168 · 2025 · External reference
Unresolved reference
2025 · External reference
Antimicrobial combinations
2005 · External reference
Plasma and intrapulmonary pharmacokinetics of funobactam, a novel diazabicyclooctane β-lactamase inhibitor, administered in combination with imipenem/cilastatin in healthy subjects
10.1128/aac.00524-26 · 2026 · External reference
Clinical relevance of bacteriostatic versus bactericidal mechanisms of action in the treatment of Gram-positive bacterial infections
10.1086/381972 · 2004 · External reference
Epidemiology of carbapenem-resistant Gram-negative infections globally
10.1097/qco.0000000000000608 · 2019 · External reference
Changing Epidemiology and Decreased Mortality Associated With Carbapenem-resistant Gram-negative Bacteria, 2000-2017
10.1093/cid/ciaa1464 · 2021 · External reference
New Delhi Metallo-beta-Lactamase 1 Catalyzes Avibactam and Aztreonam Hydrolysis
10.1128/aac.01224-17 · 2017 · External reference
In vitro activity of aztreonam in combination with newly developed beta-lactamase inhibitors against MDR Enterobacterales and Pseudomonas aeruginosa producing metallo-beta-lactamases
10.1093/jac/dkac360 · 2023 · External reference
Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies
10.1016/j.biotechadv.2018.11.013 · 2019 · External reference
Global spread of drug-resistant Acinetobacter baumannii: molecular epidemiology and management of antimicrobial resistance
10.2217/fmb.11.23 · 2011 · External reference
Susceptibility of Carbapenem-Resistant Acinetobacter baumannii and Carbapenem-Resistant Klebsiella pneumoniae Against Cefiderocol with Reference to Their Genetic Profile in India
10.1177/10766294261426703 · 2026 · External reference
Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii
10.1128/aac.04808-14 · 2015 · External reference
Pharmacokinetic interactions of ceftazidime, imipenem and aztreonam with amikacin in healthy volunteers
10.1016/j.ijantimicag.2003.07.001 · 2004 · External reference
Plasma and intrapulmonary pharmacokinetics of funobactam, a novel diazabicyclooctane β-lactamase inhibitor, administered in combination with imipenem/cilastatin in healthy subjects
10.1128/aac.00524-26 · 2026 · External reference
Pharmacokinetics, Safety, and Tolerability of Intravenous Durlobactam and Sulbactam in Subjects with Renal Impairment and Healthy Matched Control Subjects
2019 · External reference
Carbapenamase-Producing Acinetobacter baumannii in China, Latin America and the Caribbean: A Systematic Review and Meta-Analysis
10.37757/mr2022.v24.n1.8 · 2022 · External reference
