Research graph
References from Comprehensive structural and functional characterization of class 3 L-asparaginases from selected pathogenic fungi. Local targets link to admitted publications; unresolved targets remain external evidence.
Current applications and different approaches for microbial l-asparaginase production, Braz
2016 · External reference
Structural and functional diversity of asparaginases: Overview and recommendations for a revised nomenclature
10.1002/bab.2127 · 2022 · External reference
Structural and biophysical aspects of l-asparaginases: a growing family with amazing diversity
10.1107/s2052252521006011 · 2021 · External reference
Massive annotation of bacterial L-asparaginases reveals their puzzling distribution and frequent gene transfer events
10.1038/s41598-022-19689-1 · 2022 · External reference
Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy
10.1073/pnas.90.4.1474 · 1993 · External reference
Crystal structure of isoaspartyl aminopeptidase in complex with L-aspartate
10.1074/jbc.m504501200 · 2005 · External reference
Towards a dependable data set of structures for L-asparaginase research
10.1107/s2059798324005461 · 2024 · External reference
L-asparaginase and PEG asparaginase--past, present, and future
10.3109/10428199309149129 · 1993 · External reference
Erwinia chrysanthemi L-asparaginase: epitope mapping and production of antigenically modified enzymes
10.1042/bj3020921 · 1994 · External reference
Structural comparison of Ntn-hydrolases
10.1110/ps.9.12.2329 · 2000 · External reference
Expression, purification and catalytic activity of Lupinus luteus asparagine beta-amidohydrolase and its Escherichia coli homolog
10.1111/j.1432-1033.2004.04254.x · 2004 · External reference
Structural aspects of L-asparaginases, their friends and relations
10.18388/abp.2006_3291 · 2006 · External reference
Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site
10.1038/s41467-021-27105-x · 2021 · External reference
Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center
10.1107/s2059798323005648 · 2023 · External reference
Stereochemical aspects of the nucleophilic attack in different classes of L-asparaginases
10.1107/s2052252525010826 · 2026 · External reference
Controlling enzyme activity by mutagenesis and metal exchange to obtain crystal structures of stable substrate complexes of Class 3 l-asparaginase
10.1111/febs.17388 · 2025 · External reference
Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV
10.3389/fchem.2024.1381032 · 2024 · External reference
Improving the Treatment of Acute Lymphoblastic Leukemia
10.1021/acs.biochem.0c00354 · 2020 · External reference
L-Asparaginase from Lachancea thermotolerans: effect of Lys99Ala on enzyme performance and in vitro Antileukemic efficacy
10.1002/biot.202400507 · 2024 · External reference
Comparative structural and kinetic study for development of a novel candidate L-asparaginase based pharmaceutical
2023 · External reference
Cell-cycle inhibition by Helicobacter pylori L-asparaginase
10.1371/journal.pone.0013892 · 2010 · External reference
Identification and validation of l-asparaginase as a potential metabolic target against Mycobacterium tuberculosis
10.1002/jcb.27169 · 2019 · External reference
Group A Streptococcal asparagine metabolism regulates bacterial virulence
10.1038/s44319-025-00447-z · 2025 · External reference
Antimicrobial-resistant Neisseria gonorrhoeae can be targeted using inhibitors against evolutionary conservedl-asparaginase
10.1002/jcb.30271 · 2022 · External reference
Eugenol derivatives prospectively inhibit l-asparaginase: A heady target protein of Salmonella typhimurium
10.1016/j.micpath.2017.11.009 · 2018 · External reference
Antimicrobial potency evaluation of free and immobilized l-asparaginase using chitosan nanoparticles
2021 · External reference
Asparaginase – an enzyme for acrylamide reduction in food product
2010 · External reference
Evaluating the potential for enzymatic acrylamide mitigation in a range of food products using an asparaginase from Aspergillus oryzae
10.1021/jf900174q · 2009 · External reference
Safety evaluation of the food enzyme asparaginase from the genetically modified Aspergillus oryzae strain NZYM-OA
2023 · External reference
Biochemical characterization and immobilization of Erwinia carotovoral-asparaginase in a microplate for high-throughput biosensing of l-asparagine
10.1016/j.enzmictec.2016.06.013 · 2016 · External reference
L-Asparaginase-Based Biosensors
10.3390/encyclopedia1030065 · 2021 · External reference
Heterologous protein production in filamentous fungi
10.1007/s00253-023-12660-8 · 2023 · External reference
Identification and pathogenicity of Botryosphaeria parva associated with grapevine decline in Kurdistan region-Iraq
10.5586/aa.2012.045 · 2012 · External reference
Population genetic analyses of the fungal pathogen colletotrichum fructicola on tea-oil trees in China
2016 · External reference
A review of Fusarium oxysporum on its plant interaction and industrial use
10.22271/plants.2018.v6.i3b.07 · 2018 · External reference
Fusarium wilt of banana: current knowledge on epidemiology and research needs toward sustainable disease management
10.3389/fpls.2018.01468 · 2018 · External reference
Genome, transcriptome, and functional analyses of Penicillium expansum provide new insights into secondary metabolism and pathogenicity
10.1094/mpmi-09-14-0261-fi · 2015 · External reference
Diversity, application, and synthetic biology of industrially important Aspergillus fungi
10.1111/j.1365-2672.2005.02719.x · 2017 · External reference
Epidemiological and genomic landscape of azole resistance mechanisms in aspergillus fungi
10.3389/fmicb.2016.01382 · 2016 · External reference
A novel cause of invasive pulmonary infection in an immunocompetent patient: Aspergillus candidus
10.1016/j.jinf.2005.02.020 · 2005 · External reference
Biochemical characterization of L-asparaginase isoforms from Rhizobium etli-the boosting effect of zinc
10.3389/fchem.2024.1373312 · 2024 · External reference
The purification and properties of asparaginase from Lupinus species
10.1016/s0031-9422(00)94149-9 · 1978 · External reference
What makes a good new therapeutic L-asparaginase?
10.1007/s11274-019-2731-9 · 2019 · External reference
Sato, l-Asparaginase from Aspergillus spp.: production based on kinetics, thermal stability and biochemical characterization, 3
2019 · External reference
Role of asparaginase enzyme in food processing industry to reduce the acrylamide level-a review
2018 · External reference
Probing the active site of class 3 L-asparaginase by mutagenesis: mutations of the Ser-Lys tandems of ReAV
10.3390/biom15070944 · 2025 · External reference
Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification
10.1038/s42004-024-01236-w · 2024 · External reference
Efficient acrylamide adduct formation suggests dual applications of ReAIV L-asparaginase
2026 · External reference
Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase
10.1073/pnas.75.10.4806 · 1978 · External reference
Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
10.1021/bi9007963 · 2009 · External reference
Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance
10.1074/jbc.ra119.012489 · 2020 · External reference
What can be done with a good crystal and an accurate beamline?
10.1107/s0907444906038534 · 2006 · External reference
Molecular basis of bicyclic boronate beta-lactamase inhibitors of ultrabroad efficacy - insights from molecular dynamics simulation studies
10.3389/fmicb.2021.721826 · 2021 · External reference
Antifungal agent tavaborole as a potential broad-spectrum serine and metallo-beta-lactamases inhibitor
10.1016/j.ebiom.2025.105754 · 2025 · External reference
ZINC20-a free ultralarge-scale chemical database for ligand discovery
10.1021/acs.jcim.0c00675 · 2020 · External reference
Automatic clustering of docking poses in virtual screening process using self-organizing map
10.1093/bioinformatics/btp623 · 2010 · External reference
UniProt: the universal protein knowledgebase in 2023
10.1093/nar/gkac1052 · 2023 · External reference
Protein database searches using compositionally adjusted substitution matrices
10.1111/j.1742-4658.2005.04945.x · 2005 · External reference
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10.1016/s0168-9525(00)02024-2 · 2000 · External reference
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
10.1093/nar/22.22.4673 · 1994 · External reference
BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT
1999 · External reference
Protein identification and analysis tools on the expasy server
2005 · External reference
eSPC: an online data-analysis platform for molecular biophysics
10.1107/s2059798321008998 · 2021 · External reference
The MORPHEUS protein crystallization screen
10.1107/s0021889809042022 · 2009 · External reference
P13, the EMBL macromolecular crystallography beamline at the low-emittance PETRA III ring for high- and low-energy phasing with variable beam focusing
10.1107/s1600577516016465 · 2017 · External reference
Xds
10.1107/s0907444909047337 · 2010 · External reference
Phaser crystallographic software
10.1107/s0021889807021206 · 2007 · External reference
Accurate structure prediction of biomolecular interactions with AlphaFold 3
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ACHESYM: an algorithm and server for standardized placement of macromolecular models in the unit cell
10.1107/s1399004714024572 · 2014 · External reference
Towards automated crystallographic structure refinement with phenix.refine
10.1107/s0907444912001308 · 2012 · External reference
Macromolecular TLS refinement in REFMAC at moderate resolutions
10.1016/s0076-6879(03)74014-2 · 2003 · External reference
Features and development of Coot
10.1107/s0907444910007493 · 2010 · External reference
Uni-dock: GPU-accelerated docking enables ultralarge virtual screening
10.1021/acs.jctc.2c01145 · 2023 · External reference
Contact-based ligand-clustering approach for the identification of active compounds in virtual screening
2012 · External reference
UCSF Chimera--a visualization system for exploratory research and analysis
10.1002/jcc.20084 · 2004 · External reference
MolProbity: all-atom structure validation for macromolecular crystallography
10.1107/s0907444909042073 · 2010 · External reference
CheckMyMetal: a macromolecular metal-binding validation tool
10.1107/s2059798317001061 · 2017 · External reference
Automated and accurate deposition of structures solved by X-ray diffraction to the Protein Data Bank
10.1107/s0907444904019419 · 2004 · External reference
